SE8203245L - PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES - Google Patents

PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES

Info

Publication number
SE8203245L
SE8203245L SE8203245A SE8203245A SE8203245L SE 8203245 L SE8203245 L SE 8203245L SE 8203245 A SE8203245 A SE 8203245A SE 8203245 A SE8203245 A SE 8203245A SE 8203245 L SE8203245 L SE 8203245L
Authority
SE
Sweden
Prior art keywords
procedure
proline derivatives
substituted proline
enantioselective preparation
formula
Prior art date
Application number
SE8203245A
Other languages
Swedish (sv)
Inventor
E Decorte
T Kovac
V Sunjic
R Toso
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21984/81A external-priority patent/IT1194797B/en
Priority claimed from IT21201/82A external-priority patent/IT1151754B/en
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of SE8203245L publication Critical patent/SE8203245L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a novel enantioselective synthesis of the compound N-[(2S)-3-mercapto-2-methylpropionyl]-S-proline of the formula I: <IMAGE> in which X denotes an SH group, using cyclic compounds of the formula II: <IMAGE> in which Y denotes sulphur or oxygen, as starting material.
SE8203245A 1981-05-27 1982-05-25 PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES SE8203245L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21984/81A IT1194797B (en) 1981-05-27 1981-05-27 PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED DERIVATIVES OF PROLINA
IT21201/82A IT1151754B (en) 1982-05-11 1982-05-11 Prepn. of 3-mercapto-2-methyl propionyl-proline and precursors

Publications (1)

Publication Number Publication Date
SE8203245L true SE8203245L (en) 1982-11-28

Family

ID=26327821

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8203245A SE8203245L (en) 1981-05-27 1982-05-25 PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES

Country Status (6)

Country Link
DE (1) DE3219985A1 (en)
ES (1) ES512564A0 (en)
FI (1) FI77037C (en)
GR (1) GR76449B (en)
NL (1) NL8202153A (en)
SE (1) SE8203245L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
NL180746C (en) * 1983-11-18 1987-04-16 Matthijs Cornelis Evers PROCESS FOR PREPARING CAPTOPRIL.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
ES8307222A1 (en) 1983-07-01
NL8202153A (en) 1982-12-16
FI77037C (en) 1989-01-10
GR76449B (en) 1984-08-10
ES512564A0 (en) 1983-07-01
FI77037B (en) 1988-09-30
FI821859A0 (en) 1982-05-26
DE3219985A1 (en) 1982-12-16

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