SE8107683L - xanthine - Google Patents

xanthine

Info

Publication number
SE8107683L
SE8107683L SE8107683A SE8107683A SE8107683L SE 8107683 L SE8107683 L SE 8107683L SE 8107683 A SE8107683 A SE 8107683A SE 8107683 A SE8107683 A SE 8107683A SE 8107683 L SE8107683 L SE 8107683L
Authority
SE
Sweden
Prior art keywords
substituted
diaminouracil
alkanoylamido
cyclisation
tetrahydrofuryl
Prior art date
Application number
SE8107683A
Other languages
Swedish (sv)
Inventor
Mauri J Moragues
Noverola A Vega
Soto J M Prieto
R G W Spickett
Original Assignee
Fordonal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordonal Sa filed Critical Fordonal Sa
Publication of SE8107683L publication Critical patent/SE8107683L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Xanthine derivatives of the general formula <IMAGE> in which R<1> and R<3> each denote an alkyl group having 1-6 carbon atoms and R<2> denotes a cyclohexenyl, furyl, tetrahydrofuryl or thienyl group, and pharmacologically tolerable salts thereof with an alkali metal or a nitrogen-containing base, are novel, therapeutically useful compounds. They are particularly useful in the treatment of the respiratory and cardiovascular system. They can be prepared by cyclisation of a suitable 5-alkanoylamido-substituted 4-aminouracil compound or by reaction of a suitable substituted 5,6-diaminouracil with the anhydride of an acid R<3>-COOH.
SE8107683A 1980-12-23 1981-12-21 xanthine SE8107683L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8041247 1980-12-23
GB8121332 1981-07-10

Publications (1)

Publication Number Publication Date
SE8107683L true SE8107683L (en) 1982-06-24

Family

ID=26277965

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8107683A SE8107683L (en) 1980-12-23 1981-12-21 xanthine

Country Status (16)

Country Link
AR (1) AR229037A1 (en)
AU (1) AU7868481A (en)
DE (1) DE3150550A1 (en)
DK (1) DK571581A (en)
ES (1) ES8304980A1 (en)
FI (1) FI814105L (en)
FR (1) FR2498602A1 (en)
GR (1) GR76972B (en)
IT (1) IT1195301B (en)
LU (1) LU83849A1 (en)
MA (1) MA19357A1 (en)
NL (1) NL8105749A (en)
NO (1) NO814373L (en)
NZ (1) NZ199340A (en)
PT (1) PT74190B (en)
SE (1) SE8107683L (en)

Also Published As

Publication number Publication date
GR76972B (en) 1984-09-04
ES508103A0 (en) 1983-04-01
NL8105749A (en) 1982-07-16
AU7868481A (en) 1982-07-01
PT74190A (en) 1982-01-01
NO814373L (en) 1982-06-24
FR2498602A1 (en) 1982-07-30
PT74190B (en) 1983-05-20
FI814105L (en) 1982-06-24
IT8125728A0 (en) 1981-12-21
IT1195301B (en) 1988-10-12
AR229037A1 (en) 1983-05-31
DK571581A (en) 1982-06-24
ES8304980A1 (en) 1983-04-01
DE3150550A1 (en) 1982-08-12
MA19357A1 (en) 1982-07-01
LU83849A1 (en) 1982-05-07
NZ199340A (en) 1984-07-06

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