SE8104227L - BIOLOGICAL INTERESTING ASSOCIATIONS MARKED WITH DICHLORTRIAZINYL-AMINOFLUORESCEIN - Google Patents

BIOLOGICAL INTERESTING ASSOCIATIONS MARKED WITH DICHLORTRIAZINYL-AMINOFLUORESCEIN

Info

Publication number
SE8104227L
SE8104227L SE8104227A SE8104227A SE8104227L SE 8104227 L SE8104227 L SE 8104227L SE 8104227 A SE8104227 A SE 8104227A SE 8104227 A SE8104227 A SE 8104227A SE 8104227 L SE8104227 L SE 8104227L
Authority
SE
Sweden
Prior art keywords
aminofluorescein
dichlortriazinyl
marked
amino
triazine ring
Prior art date
Application number
SE8104227A
Other languages
Swedish (sv)
Inventor
C-H J Wang
S D Stroupe
M E Jolley
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of SE8104227L publication Critical patent/SE8104227L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Fluorescent derivatives of biologically interesting compounds which permit the detection and determination of said compounds in body fluids such as serum, plasma, saliva and urine, are characterized by the formula: <IMAGE> wherein X is a biologically interesting moiety having a molecular weight of less than 2,000 and having at least one primary or secondary amine or hydroxyl group by which it attaches to a carbon atom of the triazine ring; and Z is 4-aminofluorescein or 5- aminofluorescein attached through the 4-amino or 5-amino, respectively to the 2-position of the triazine ring.
SE8104227A 1980-07-30 1981-07-07 BIOLOGICAL INTERESTING ASSOCIATIONS MARKED WITH DICHLORTRIAZINYL-AMINOFLUORESCEIN SE8104227L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17355380A 1980-07-30 1980-07-30

Publications (1)

Publication Number Publication Date
SE8104227L true SE8104227L (en) 1982-01-31

Family

ID=22632537

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104227A SE8104227L (en) 1980-07-30 1981-07-07 BIOLOGICAL INTERESTING ASSOCIATIONS MARKED WITH DICHLORTRIAZINYL-AMINOFLUORESCEIN

Country Status (9)

Country Link
JP (1) JPS5758695A (en)
AU (1) AU554360B2 (en)
BE (1) BE889788A (en)
CA (1) CA1160626A (en)
DE (1) DE3129705A1 (en)
FR (1) FR2487835A1 (en)
GB (1) GB2081257B (en)
IT (1) IT1137630B (en)
SE (1) SE8104227L (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476228A (en) * 1982-11-08 1984-10-09 Abbott Laboratories Determination of unsaturated thyroxine binding protein sites using fluorescence polarization techniques
US4476229A (en) * 1982-11-08 1984-10-09 Abbott Laboratories Substituted carboxyfluoresceins
US4681859A (en) * 1984-09-21 1987-07-21 Ortho Diagnostic Systems Inc. Fluorescence polarization immunoassay for heavy antigens
EP0199042A1 (en) * 1985-03-26 1986-10-29 Abbott Laboratories Procainamide assay, tracers, immunogens and antibodies
DE3682105D1 (en) * 1985-04-01 1991-11-28 Abbott Lab SAMPLE, TRACERS, IMMUNOGENIC AND ANTIBODIES OF ETHOSUXIMID.
EP0218010A3 (en) * 1985-07-10 1988-01-07 Abbott Laboratories Ligand detection method and substituted carboxyfluorescein tracers therefor
US4902630A (en) * 1985-07-22 1990-02-20 Abbott Laboratories Fluorescence polarization immunoassy and reagents for measurement of c-reactive protein
DE3685377D1 (en) * 1985-07-22 1992-06-25 Abbott Lab FLUORESCENCE POLARIZATION IMMUNOTEST AND REAGENT FOR MEASURING C-REACTIVE PROTEIN.
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
EP0457213B1 (en) * 1990-05-16 1997-07-23 Abbott Laboratories Barbiturate assay, tracers, immunogens, antibodies and kit
FR2683911B1 (en) * 1991-11-15 1995-02-03 Clonatec DIAGNOSTIC REAGENT, ITS APPLICATIONS IN A PROCESS FOR THE QUICK QUALITATIVE AND QUANTITATIVE DETERMINATION OF AN ANALYTE IN A TEST FLUID AND DEVICE FOR CARRYING OUT SAID METHOD.
IT1298693B1 (en) * 1996-04-24 2000-01-12 Hoffmann La Roche 4'-METHYL SUBSTITUTED FLUORESCEIN DERIVATIVES
WO2005036169A2 (en) * 2003-10-03 2005-04-21 Cumbre Inc. Fluorescent probes for ribosomes and method of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998943A (en) * 1973-10-02 1976-12-21 Syva Company Double receptor fluorescent immunoassay
CA1086306A (en) * 1976-12-06 1980-09-23 Dennis Blakeslee Immunofluorescence reagent and process for preparing same
US4213904A (en) * 1979-02-28 1980-07-22 Haugland Richard P Fluorescent labeling reagents containing the fluorescein and eosin chromophores

Also Published As

Publication number Publication date
AU554360B2 (en) 1986-08-21
CA1160626A (en) 1984-01-17
IT8123207A0 (en) 1981-07-28
DE3129705A1 (en) 1982-05-27
IT1137630B (en) 1986-09-10
GB2081257A (en) 1982-02-17
GB2081257B (en) 1984-11-07
FR2487835B1 (en) 1984-03-16
BE889788A (en) 1982-01-29
FR2487835A1 (en) 1982-02-05
AU7203681A (en) 1982-02-04
DE3129705C2 (en) 1988-03-10
JPS5758695A (en) 1982-04-08

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