SE7910151L - BENZOXADIAZOLES AND BENSTIADIAZOLES - Google Patents

BENZOXADIAZOLES AND BENSTIADIAZOLES

Info

Publication number
SE7910151L
SE7910151L SE7910151A SE7910151A SE7910151L SE 7910151 L SE7910151 L SE 7910151L SE 7910151 A SE7910151 A SE 7910151A SE 7910151 A SE7910151 A SE 7910151A SE 7910151 L SE7910151 L SE 7910151L
Authority
SE
Sweden
Prior art keywords
benstiadiazoles
benzoxadiazoles
compounds
spasms
muscles
Prior art date
Application number
SE7910151A
Other languages
Unknown language ( )
Swedish (sv)
Inventor
P Neumann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1288878A external-priority patent/CH640852A5/en
Priority claimed from CH1289078A external-priority patent/CH643841A5/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE7910151L publication Critical patent/SE7910151L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Compounds of formula I, <IMAGE> wherein X is oxygen or sulphur, and R1-R6 are various substituents. The compounds are useful for treating coronary insufficiency, intermittent claudication, cerebrovascular insults, spasms in muscles and hypertension.
SE7910151A 1978-12-18 1979-12-10 BENZOXADIAZOLES AND BENSTIADIAZOLES SE7910151L (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH1288878A CH640852A5 (en) 1978-12-18 1978-12-18 1,4-Dihydropyridine derivatives, their preparation and use
CH1289078A CH643841A5 (en) 1978-12-18 1978-12-18 Novel 1,4-dihydropyridine derivatives, their preparation and use
CH347779 1979-04-11
CH347279 1979-04-11
CH562779 1979-06-15

Publications (1)

Publication Number Publication Date
SE7910151L true SE7910151L (en) 1980-06-19

Family

ID=27509137

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7910151A SE7910151L (en) 1978-12-18 1979-12-10 BENZOXADIAZOLES AND BENSTIADIAZOLES

Country Status (7)

Country Link
CA (1) CA1131228A (en)
DE (1) DE2949464A1 (en)
GB (1) GB2041358B (en)
IL (1) IL58974A (en)
NZ (1) NZ192421A (en)
PT (1) PT70601A (en)
SE (1) SE7910151L (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (en) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-THIAZOLE or 4-IMIDAZOLE-SUBSTITUTED, 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM
CH655658B (en) * 1980-09-18 1986-05-15
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
ATE50987T1 (en) * 1982-05-10 1990-03-15 Takeda Chemical Industries Ltd DIHYDROPYRIDE DERIVATIVES, THEIR PREPARATION AND USE.
FR2528431B1 (en) * 1982-06-15 1986-01-10 Sandoz Sa NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
WO1985000169A1 (en) * 1983-06-21 1985-01-17 Sandoz Ag 1,4-dihydropyridine derivatives, production thereof and pharmaceutical preparations containing them
FR2554109A1 (en) * 1983-11-01 1985-05-03 Sandoz Sa NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND USE IN THERAPEUTICS AS MEDICAMENTS
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
IT1201454B (en) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-dihydropyridine-2-SUBSTITUTED

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (en) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridine-33-dicarboxylic acid alkyl ester
DE2117571C3 (en) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Asymmetrical 1,4-dihydropyridine-33-dicarboxylic acid esters, process for their preparation and their use as pharmaceuticals
DE2218644C3 (en) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basic esters of 1,4-dihydropyridines, processes for their preparation and their use as pharmaceuticals
GB1455502A (en) * 1973-02-20 1976-11-10 Yamanouchi Pharma Co Ltd 1,4-dihydropyridine derivatives
FR2320750A1 (en) * 1975-08-12 1977-03-11 Hexachimie 1,4-DIHYDRO PYRIDINES AND THEIR THERAPEUTIC APPLICATION
DE2616991A1 (en) * 1976-04-17 1977-10-27 Bayer Ag Thio-substd. dihydro-pyridine derivs. - coronary vasodilators and antihypertensives prepd. e.g. by reacting dicarbonyl cpds. with amines and thio-substd. ketones
DE2740080A1 (en) * 1977-09-06 1979-03-15 Bayer Ag 2-Aminoalkyl-1,4-di:hydro-pyridine derivs. - with broad spectrum of effects on the heart and circulation, e.g. lowering blood pressure and spasmolytic effect

Also Published As

Publication number Publication date
IL58974A (en) 1983-03-31
PT70601A (en) 1980-01-01
GB2041358B (en) 1982-11-17
DE2949464A1 (en) 1980-06-26
GB2041358A (en) 1980-09-10
IL58974A0 (en) 1980-03-31
CA1131228A (en) 1982-09-07
NZ192421A (en) 1982-09-07

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