SE7908060L - PROCEDURE FOR THE PREPARATION OF A THERAPEUTIC ACTIVE PROPANOLAMINE - Google Patents
PROCEDURE FOR THE PREPARATION OF A THERAPEUTIC ACTIVE PROPANOLAMINEInfo
- Publication number
- SE7908060L SE7908060L SE7908060A SE7908060A SE7908060L SE 7908060 L SE7908060 L SE 7908060L SE 7908060 A SE7908060 A SE 7908060A SE 7908060 A SE7908060 A SE 7908060A SE 7908060 L SE7908060 L SE 7908060L
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- propanolamine
- procedure
- therapeutic active
- isopropylamino
- Prior art date
Links
- WUGQZFFCHPXWKQ-UHFFFAOYSA-N Propanolamine Chemical compound NCCCO WUGQZFFCHPXWKQ-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- OFRYBPCSEMMZHR-UHFFFAOYSA-N alpha-Hydroxymetoprolol Chemical compound COCC(O)C1=CC=C(OCC(O)CNC(C)C)C=C1 OFRYBPCSEMMZHR-UHFFFAOYSA-N 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229960004592 isopropanol Drugs 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to a process for the preparation of 1-isopropylamino-3-[4-(2-methoxyethyl]-phenoxy]-2- propanol with the formula <IMAGE> by reacting 1-isopropylamino-3-[4-(1-hydroxy-2- methoxyethyl)-phenoxy]-2-propanol with sodium borohydride in an inert solvent containing trifluoroacetic acid, methane sulphonic acid or p-toluene sulphonic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7908060A SE426317B (en) | 1979-09-28 | 1979-09-28 | Process for the preparation of 1-isopropylamino-3-[4-(2- methoxyethyl)-phenoxy]-2-propanol or acid addition salts thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7908060A SE426317B (en) | 1979-09-28 | 1979-09-28 | Process for the preparation of 1-isopropylamino-3-[4-(2- methoxyethyl)-phenoxy]-2-propanol or acid addition salts thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7908060L true SE7908060L (en) | 1981-03-29 |
| SE426317B SE426317B (en) | 1982-12-27 |
Family
ID=20338921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7908060A SE426317B (en) | 1979-09-28 | 1979-09-28 | Process for the preparation of 1-isopropylamino-3-[4-(2- methoxyethyl)-phenoxy]-2-propanol or acid addition salts thereof |
Country Status (1)
| Country | Link |
|---|---|
| SE (1) | SE426317B (en) |
-
1979
- 1979-09-28 SE SE7908060A patent/SE426317B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE426317B (en) | 1982-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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