SE7901799L - AMINOALDEHYDE DERIVATIVE - Google Patents
AMINOALDEHYDE DERIVATIVEInfo
- Publication number
- SE7901799L SE7901799L SE7901799A SE7901799A SE7901799L SE 7901799 L SE7901799 L SE 7901799L SE 7901799 A SE7901799 A SE 7901799A SE 7901799 A SE7901799 A SE 7901799A SE 7901799 L SE7901799 L SE 7901799L
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- cho
- acetals
- hydrogen
- independently represent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Hydrolysable acetals and hemiacetals of aminoaldehydes having the formula 1:- R(NHA<1>)rNHA<2>CHO (1> wherein R represents hydrogen or -A<3>CHO; A<1>, A<2> and A<3> independently represent divalent alkylene (including cycloalkylene) groups; and r represents 0 or an integer inhibit cell proliferation and are believed to be useful in the treatment of cancer and tissue and organ rejection and in contraception. Preferred acetals are those of the formula 5:- <IMAGE> wherein R<5> represents hydrogen, (CH2)p CHO or <IMAGE> n, m and p independently represent integers from 2 to 12; and R<3> and R<4> independently represent alkyl or alkenyl groups containing 1 to 6 carbon atoms and optionally substituted by hydroxy, alkoxy or halogen or R<3> and R<4> together represent an alkylene group containing 2 or 3 carbon atoms. Some, but not all, of the acetals and hemiacetals are novel compounds. The novel compounds include those of formula 1 in which R is hydrogen and r is 1 and those of formula 5 in which R<5> is hydrogen and r is 1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB865678 | 1978-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7901799L true SE7901799L (en) | 1979-09-04 |
Family
ID=9856702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7901799A SE7901799L (en) | 1978-03-03 | 1979-02-28 | AMINOALDEHYDE DERIVATIVE |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS55354A (en) |
| AU (1) | AU522696B2 (en) |
| BE (1) | BE874552A (en) |
| DE (1) | DE2908032A1 (en) |
| DK (1) | DK85779A (en) |
| ES (1) | ES478776A1 (en) |
| FR (1) | FR2418786A1 (en) |
| GB (1) | GB2017492B (en) |
| IN (1) | IN151435B (en) |
| IT (1) | IT1114723B (en) |
| LU (1) | LU80991A1 (en) |
| NL (1) | NL7901716A (en) |
| SE (1) | SE7901799L (en) |
| ZA (1) | ZA79925B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5998015A (en) * | 1982-11-27 | 1984-06-06 | Microbial Chem Res Found | Immunoactivator |
| AU622720B2 (en) * | 1988-10-26 | 1992-04-16 | Ortho Pharmaceutical Corporation | The use of oxidized polyamines, especially nn'-bis-(3- propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents |
| US5374658A (en) * | 1988-10-26 | 1994-12-20 | Ortho Phamaceutical Corporation | Use of oxidized polyamines, especially NN'-bis-(3-propionaldehyde)-1-4-diaminobutane (spermine dialdehye) in graft treatment |
-
1979
- 1979-02-27 ZA ZA79925A patent/ZA79925B/en unknown
- 1979-02-27 FR FR7904948A patent/FR2418786A1/en not_active Withdrawn
- 1979-02-27 AU AU44646/79A patent/AU522696B2/en not_active Ceased
- 1979-02-28 DK DK85779A patent/DK85779A/en not_active Application Discontinuation
- 1979-02-28 SE SE7901799A patent/SE7901799L/en not_active Application Discontinuation
- 1979-03-01 BE BE0/193780A patent/BE874552A/en unknown
- 1979-03-01 IN IN188/CAL/79A patent/IN151435B/en unknown
- 1979-03-01 DE DE19792908032 patent/DE2908032A1/en not_active Withdrawn
- 1979-03-02 ES ES478776A patent/ES478776A1/en not_active Expired
- 1979-03-02 JP JP2501379A patent/JPS55354A/en active Pending
- 1979-03-02 IT IT48195/79A patent/IT1114723B/en active
- 1979-03-02 NL NL7901716A patent/NL7901716A/en not_active Application Discontinuation
- 1979-03-02 LU LU80991A patent/LU80991A1/en unknown
- 1979-03-05 GB GB7907641A patent/GB2017492B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2017492B (en) | 1982-11-03 |
| DE2908032A1 (en) | 1979-09-13 |
| GB2017492A (en) | 1979-10-10 |
| IT1114723B (en) | 1986-01-27 |
| LU80991A1 (en) | 1979-10-29 |
| ES478776A1 (en) | 1979-12-16 |
| JPS55354A (en) | 1980-01-05 |
| DK85779A (en) | 1979-09-04 |
| IT7948195A0 (en) | 1979-03-02 |
| AU522696B2 (en) | 1982-06-24 |
| BE874552A (en) | 1979-09-03 |
| FR2418786A1 (en) | 1979-09-28 |
| IN151435B (en) | 1983-04-16 |
| NL7901716A (en) | 1979-09-05 |
| ZA79925B (en) | 1980-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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