SE7900855L - PROCEDURE FOR THE PREPARATION OF MONORDS AND THEIR DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF MONORDS AND THEIR DERIVATIVES

Info

Publication number
SE7900855L
SE7900855L SE7900855A SE7900855A SE7900855L SE 7900855 L SE7900855 L SE 7900855L SE 7900855 A SE7900855 A SE 7900855A SE 7900855 A SE7900855 A SE 7900855A SE 7900855 L SE7900855 L SE 7900855L
Authority
SE
Sweden
Prior art keywords
monorden
derivatives
monords
procedure
preparation
Prior art date
Application number
SE7900855A
Other languages
Swedish (sv)
Inventor
M A Espenshade
G J Calton
Original Assignee
Grace W R & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/874,207 external-priority patent/US4166764A/en
Priority claimed from US05/955,705 external-priority patent/US4228079A/en
Application filed by Grace W R & Co filed Critical Grace W R & Co
Publication of SE7900855L publication Critical patent/SE7900855L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Monorden is produced by cultivation of Diheterospora chlamydosporia. The cultivation takes place in a nutrient medium and the monorden is isolated by adsorption or extraction. It may be converted by alkylation into new derivatives of the formula: <IMAGE> wherein R is alkyl of 2 to 8 carbon atoms, the two R groups being the same or different. Monorden is a known anti-tumour agent. The new derivatives are anti-tumour agents and nematocides.
SE7900855A 1978-02-01 1979-01-31 PROCEDURE FOR THE PREPARATION OF MONORDS AND THEIR DERIVATIVES SE7900855L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87434878A 1978-02-01 1978-02-01
US05/874,207 US4166764A (en) 1978-02-01 1978-02-01 Production of monorden
US05/955,705 US4228079A (en) 1978-10-30 1978-10-30 Dialkoxy monorden derivatives

Publications (1)

Publication Number Publication Date
SE7900855L true SE7900855L (en) 1979-08-02

Family

ID=27420481

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7900855A SE7900855L (en) 1978-02-01 1979-01-31 PROCEDURE FOR THE PREPARATION OF MONORDS AND THEIR DERIVATIVES

Country Status (4)

Country Link
DE (1) DE2903997A1 (en)
GB (1) GB2013672B (en)
NL (1) NL7900817A (en)
SE (1) SE7900855L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650430A (en) * 1990-06-06 1997-07-22 Sankyo Company, Limited Radicicol derivatives, their preparation and their anti-tumor activity
IE911915A1 (en) * 1990-06-06 1991-12-18 Sankyo Co Radicicol derivatives, their preparation and their¹anti-tumor activity

Also Published As

Publication number Publication date
GB2013672B (en) 1982-06-09
NL7900817A (en) 1979-08-03
DE2903997A1 (en) 1979-09-06
GB2013672A (en) 1979-08-15

Similar Documents

Publication Publication Date Title
BG38639A3 (en) Method for preparing ester derivatives of 6- beta- hydroxymethylpenicillanic acid
FR2416222A1 (en) PERFLUOROALKYL-THIOETHYL-ETHER DERIVATIVES
PT77344A (en) Process for the preparation of new diazabicyclo-3,3,1-nonanes
ES526318A0 (en) PROCEDURE FOR THE OBTAINING OF SUBSTITUTED 1-HYDROXYETHYL-TRIAZOLYL DERIVATIVES
RO77559A (en) PROCESS FOR PREPARING ERYTRO-9- (2-HYDROXY-3-ALKYL) HYDROXANTINE
FR2423495A1 (en) CARBOXHYDRAZIDE C-3 ANTI-TUMOR DERIVATIVES OF 4-DESACETYL VINCALEUBLASTINE
NO173549C (en) New Organic Compounds, Procedures for their Preparation, and Use thereof
FR2377367A1 (en) PROCESS FOR THE PREPARATION OF ALCOXY-KETONES
DE3070227D1 (en) Benzothiazole derivatives, pharmaceutical compositions containing them and process for their preparation
SE7900855L (en) PROCEDURE FOR THE PREPARATION OF MONORDS AND THEIR DERIVATIVES
SE7608608L (en) PROCEDURE FOR MAKING NEW DIAMINO ANDROSTANES
BG32849A3 (en) Method for obtaining of 2- chlor- 4- substituated derivatives of thiazolcarbonic acids
JPS5615298A (en) Sisomicin derivative
BG33292A3 (en) Method for obtaining of penamsulphooxide derivatives
FR2446841A1 (en) PROCESS FOR THE PREPARATION OF 1A, 3B-DIHYDROXY-D5-STEROIDES
DE2960324D1 (en) 4,5-methano-bufadienolide-rhamnosides, process for their preparation and medicines containing them
FR2369288A1 (en) PROCESS FOR THE PREPARATION OF ORGANIC TIN COMPOUNDS
ES451466A1 (en) 5-thiazole-methane-amines, and their use as antilipolytics
FI890187A0 (en) FOERFARANDE FOER FRAMSTAELLNING AV HYDROXIALKYLERANDE FOERENINGAR, SAOLUNDA ERHAOLLNA NYA FOERENINGAR OCH DERAS ANVAENDNING.
BG35896A3 (en) Method for preparing 3- halogen- 3- cephem compounds
BE846663A (en) PROCESS FOR PREPARING ALKYL DIETHERS OF ETHYLENE-GLYCOLS
SE7708452L (en) COMPOSITION CONTAINING AN ANTHRAKINON COMPOUND
FR2429211A1 (en) PROCESS FOR THE PRODUCTION OF N-METHYLBENZOTHIAZOLONE DERIVATIVES SUBSTITUTED IN POSITION 4
SE7811761L (en) 4,5,6,7-TETRAHYDROIMIDAZO- (4,5-C), PYRIDINE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
DE3260314D1 (en) Derivatives of 4-methyl-3-formyl-pentanoic acid, their process of preparation and their application in the preparation of cyclic derivatives

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7900855-3

Format of ref document f/p: F