SE7503657L - - Google Patents

Info

Publication number
SE7503657L
SE7503657L SE7503657A SE7503657A SE7503657L SE 7503657 L SE7503657 L SE 7503657L SE 7503657 A SE7503657 A SE 7503657A SE 7503657 A SE7503657 A SE 7503657A SE 7503657 L SE7503657 L SE 7503657L
Authority
SE
Sweden
Prior art keywords
alpha
formula
diole
xylene
stands
Prior art date
Application number
SE7503657A
Other versions
SE433608B (en
Inventor
J Ruohonen
Original Assignee
Huhtamaeki Yhthymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huhtamaeki Yhthymae Oy filed Critical Huhtamaeki Yhthymae Oy
Publication of SE7503657L publication Critical patent/SE7503657L/xx
Publication of SE433608B publication Critical patent/SE433608B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a method for producing therapeutically valuable .alpha.2-tert.-butylaminomethyl-4-hydroxy-m-xylene-.alpha.2 ,.alpha.3-diole, which has the formula and its acid addition salts, characterized in that an imine derivative having the formula where R stands for a lower straight-chain or branched hydrocarbon radical containing 1 to 6 carbon atoms, and Ar stands for an aryl group, is converted by simultaneous hydrogenation and reduction into a compound having the formula and from which the arylmethyl protective group is removed by catalytic hydration. The method, according to the invention, is appropriate for industrial production work wherein .alpha.2-tert.-buty-laminomethyl-4-hydroxy-m-xylene-.alpha.1,.alpha.3-diole can be easily produced with a good yield in a continuous process, without isolating the intermediate products.
SE7503657A 1974-03-29 1975-03-27 NEW INDUSTRIAL PROCEDURE FOR PREPARING ALFA? 721-TERT.-BUTYLAMINOMETHYL-4-HYDROXY-M-XYLENE-ALFA? 721, ALFA? 723-DIOL SE433608B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI982/74A FI56673C (en) 1974-03-29 1974-03-29 NYTT FOERFARANDE FOER FRAMSTAELLNING AV ALFA-TERT-BYTYLAMINOMETHYL-4-HYDROXY-M-XYLEN-ALFA1 ALFA3-DIOL

Publications (2)

Publication Number Publication Date
SE7503657L true SE7503657L (en) 1975-09-30
SE433608B SE433608B (en) 1984-06-04

Family

ID=8504919

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7503657A SE433608B (en) 1974-03-29 1975-03-27 NEW INDUSTRIAL PROCEDURE FOR PREPARING ALFA? 721-TERT.-BUTYLAMINOMETHYL-4-HYDROXY-M-XYLENE-ALFA? 721, ALFA? 723-DIOL

Country Status (7)

Country Link
JP (1) JPS5953256B2 (en)
CA (1) CA1040658A (en)
DK (1) DK135500C (en)
FI (1) FI56673C (en)
NO (1) NO140297C (en)
SE (1) SE433608B (en)
SU (1) SU538660A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3163871D1 (en) 1980-07-09 1984-07-05 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
FI118418B (en) 2003-04-17 2007-11-15 Ecocat Oy Aluminum-rounded catalytic converter for cleaning of gas leaks
EP1747189A1 (en) 2004-05-20 2007-01-31 Teva Pharmaceutical Fine Chemicals S.R.L. Preparation of levalbuterol hydrochloride
CN110963929B (en) * 2019-11-26 2022-10-21 安徽恒星制药有限公司 Preparation method of salbutamol hydrochloride suitable for industrial production

Also Published As

Publication number Publication date
FI98274A (en) 1975-09-30
DK133975A (en) 1975-09-30
FI56673C (en) 1981-02-04
DK135500C (en) 1977-10-24
CA1040658A (en) 1978-10-17
NO140297C (en) 1979-08-08
JPS5953256B2 (en) 1984-12-24
SE433608B (en) 1984-06-04
NO751034L (en) 1975-09-30
FI56673B (en) 1979-11-30
DK135500B (en) 1977-05-09
JPS50130732A (en) 1975-10-16
NO140297B (en) 1979-04-30
SU538660A3 (en) 1976-12-05

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