SE436029B - Process for the preparation of the nitric acid ester of N- (2-hydroxyethyl) nicotinamide - Google Patents

Process for the preparation of the nitric acid ester of N- (2-hydroxyethyl) nicotinamide

Info

Publication number
SE436029B
SE436029B SE7703868A SE7703868A SE436029B SE 436029 B SE436029 B SE 436029B SE 7703868 A SE7703868 A SE 7703868A SE 7703868 A SE7703868 A SE 7703868A SE 436029 B SE436029 B SE 436029B
Authority
SE
Sweden
Prior art keywords
nicotinamide
hydroxyethyl
preparation
acid ester
nitric acid
Prior art date
Application number
SE7703868A
Other languages
Swedish (sv)
Other versions
SE7703868L (en
Inventor
H Nagano
T Mori
S Takaku
I Matsunaga
T Kujirai
T Ogasawara
S Sugano
M Shindo
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP51036101A external-priority patent/JPS5817463B2/en
Priority claimed from JP8245876A external-priority patent/JPS6052685B2/en
Priority claimed from JP8352276A external-priority patent/JPS539775A/en
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of SE7703868L publication Critical patent/SE7703868L/en
Publication of SE436029B publication Critical patent/SE436029B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
SE7703868A 1976-04-02 1977-04-01 Process for the preparation of the nitric acid ester of N- (2-hydroxyethyl) nicotinamide SE436029B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP51036101A JPS5817463B2 (en) 1976-04-02 1976-04-02 Nicotinic acid amide derivatives
JP8245876A JPS6052685B2 (en) 1976-07-13 1976-07-13 Cardiovascular disease treatment
JP8352276A JPS539775A (en) 1976-07-15 1976-07-15 Pyridine derivatives and their preparation

Publications (2)

Publication Number Publication Date
SE7703868L SE7703868L (en) 1977-10-03
SE436029B true SE436029B (en) 1984-11-05

Family

ID=27288973

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7703868A SE436029B (en) 1976-04-02 1977-04-01 Process for the preparation of the nitric acid ester of N- (2-hydroxyethyl) nicotinamide

Country Status (13)

Country Link
AR (2) AR217423A1 (en)
AT (1) AT360532B (en)
AU (1) AU509591B2 (en)
CA (1) CA1088944A (en)
CH (1) CH633535A5 (en)
DE (1) DE2714713C3 (en)
DK (1) DK145608C (en)
ES (2) ES457421A1 (en)
FI (1) FI66598C (en)
FR (1) FR2346334A1 (en)
MX (1) MX5534E (en)
NL (2) NL176674C (en)
SE (1) SE436029B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0653658B2 (en) * 1984-12-17 1994-07-20 中外製薬株式会社 Stable tablet manufacturing method
EP0223811A1 (en) * 1985-05-22 1987-06-03 Beecham Group Plc Use of nicorandil or pinacidil for the treatment of peripheral vascular disease
AU3693789A (en) * 1988-05-10 1989-11-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) New ophthalmic preparation for treating glaucoma
US4973565A (en) * 1989-07-17 1990-11-27 Corning Incorporated Fluoroborosilicate glass and clad article
ZA91291B (en) * 1990-01-16 1991-09-25 Hoechst Ag Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
EP2307380B1 (en) * 2008-07-01 2012-10-24 Politechnika Lódzka N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases
IT1403890B1 (en) 2010-12-28 2013-11-08 Procos Spa NICORANDIL PRODUCTION PROCESS

Also Published As

Publication number Publication date
ES457421A1 (en) 1978-11-16
FI66598B (en) 1984-07-31
FI66598C (en) 1984-11-12
DE2714713A1 (en) 1977-10-20
DK145608B (en) 1982-12-27
NL930042I1 (en) 1993-08-02
DE2714713B2 (en) 1980-02-21
DK145608C (en) 1983-07-11
AR217423A1 (en) 1980-03-31
ES468462A1 (en) 1979-10-01
NL930042I2 (en) 1993-09-16
NL7703624A (en) 1977-10-04
FR2346334B1 (en) 1980-02-01
ATA235077A (en) 1980-06-15
AR220907A1 (en) 1980-12-15
CH633535A5 (en) 1982-12-15
SE7703868L (en) 1977-10-03
NL176674C (en) 1985-05-17
AU2353277A (en) 1978-09-28
AU509591B2 (en) 1980-05-15
FI771024A (en) 1977-10-03
AT360532B (en) 1981-01-12
CA1088944A (en) 1980-11-04
DK128277A (en) 1977-10-03
NL176674B (en) 1984-12-17
DE2714713C3 (en) 1980-10-16
FR2346334A1 (en) 1977-10-28
MX5534E (en) 1983-09-27

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