SE435290B - PROCEDURE FOR THE PREPARATION OF GAMMA-CRYSTALLINE FORM OF SODIUM-7- (D-ALFA-FORMYLOXY-ALFA-PHENYLACETAMIDO) - (2-METHYL-1H-TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBOXYLATE - Google Patents

PROCEDURE FOR THE PREPARATION OF GAMMA-CRYSTALLINE FORM OF SODIUM-7- (D-ALFA-FORMYLOXY-ALFA-PHENYLACETAMIDO) - (2-METHYL-1H-TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBOXYLATE

Info

Publication number
SE435290B
SE435290B SE7602565A SE7602565A SE435290B SE 435290 B SE435290 B SE 435290B SE 7602565 A SE7602565 A SE 7602565A SE 7602565 A SE7602565 A SE 7602565A SE 435290 B SE435290 B SE 435290B
Authority
SE
Sweden
Prior art keywords
alfa
yltiomethyl
cefem
phenylacetamido
formyloxy
Prior art date
Application number
SE7602565A
Other languages
Swedish (sv)
Other versions
SE7602565L (en
Inventor
K-S Yang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7602565L publication Critical patent/SE7602565L/en
Publication of SE435290B publication Critical patent/SE435290B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE7602565A 1975-04-11 1976-02-26 PROCEDURE FOR THE PREPARATION OF GAMMA-CRYSTALLINE FORM OF SODIUM-7- (D-ALFA-FORMYLOXY-ALFA-PHENYLACETAMIDO) - (2-METHYL-1H-TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBOXYLATE SE435290B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/567,324 US4006138A (en) 1975-04-11 1975-04-11 Crystalline form of sodium O-formylcefamandole

Publications (2)

Publication Number Publication Date
SE7602565L SE7602565L (en) 1976-10-12
SE435290B true SE435290B (en) 1984-09-17

Family

ID=24266692

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7602565A SE435290B (en) 1975-04-11 1976-02-26 PROCEDURE FOR THE PREPARATION OF GAMMA-CRYSTALLINE FORM OF SODIUM-7- (D-ALFA-FORMYLOXY-ALFA-PHENYLACETAMIDO) - (2-METHYL-1H-TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBOXYLATE

Country Status (31)

Country Link
US (1) US4006138A (en)
JP (1) JPS51123812A (en)
AR (1) AR210880A1 (en)
AT (1) AT343806B (en)
AU (1) AU500013B2 (en)
BE (1) BE840179A (en)
CA (1) CA1045114A (en)
CH (1) CH621554A5 (en)
CS (1) CS191970B2 (en)
DD (1) DD125950A5 (en)
DE (1) DE2614669C2 (en)
DK (1) DK148022C (en)
ES (1) ES446907A1 (en)
FI (1) FI65069C (en)
FR (1) FR2306698A1 (en)
GB (1) GB1546898A (en)
GR (1) GR59912B (en)
HU (1) HU175592B (en)
IL (1) IL49100A (en)
LU (1) LU74740A1 (en)
MX (1) MX3687E (en)
NL (1) NL184258C (en)
NO (1) NO151748C (en)
OA (1) OA05290A (en)
PL (1) PL104803B1 (en)
PT (1) PT64917B (en)
RO (1) RO68501A (en)
SE (1) SE435290B (en)
SU (1) SU668608A3 (en)
YU (1) YU40643B (en)
ZA (1) ZA761103B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7503274L (en) * 1974-04-11 1975-10-13 Ciba Geigy Ag CEFALOSPORIN
US4085277A (en) * 1975-01-30 1978-04-18 Fujisawa Pharmaceutical Co., Ltd. 7(2-Phenyl or thienyl-2-isonicotinoyloxyacetamido)-3-(1-methyl-1-H tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid
FR2400519A1 (en) * 1977-08-17 1979-03-16 Roussel Uclaf CRYSTALLINE FORM OF SODIUM SALT OF AN OXIMIN DERIVATIVE OF 7-AMINO-THIAZOLYL ACETAMIDO CEPHALOSPORANIC, ITS PREPARATION PROCESS AND ITS APPLICATION AS A MEDICINAL PRODUCT
US4168376A (en) * 1978-06-05 1979-09-18 Eli Lilly And Company Process for crystalline sodium cefamandole
US4946838A (en) * 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
EP0432297A1 (en) * 1989-12-13 1991-06-19 Technologitschen Kombinat Sa Promischlena Mikrobiologia A method for the preparation of the sodium salt of O-formyl cefamandole
US5492903A (en) * 1990-06-19 1996-02-20 Takeda Chemical Industries Ltd. Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
WO2013057196A1 (en) * 2011-10-20 2013-04-25 Dsm Sinochem Pharmaceuticals Netherlands B.V. Process for the preparation of cefamandole nafate
CN104530086B (en) * 2014-12-16 2015-12-09 天津大学 The new crystal of Cefamandole nafate compounds and crystallization preparation method thereof
CN105037392A (en) * 2015-08-13 2015-11-11 青岛蓝盛洋医药生物科技有限责任公司 Bactericidal medicine efamandole nafate compound and preparing method of bactericidal medicine efamandole nafate compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887551A (en) * 1964-11-04 1975-06-03 Glaxo Lab Ltd Crystalline forms of cephaloridine
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
YU79276A (en) 1982-10-31
DE2614669C2 (en) 1984-09-27
NL7603660A (en) 1976-10-13
BE840179A (en) 1976-09-30
AU1143576A (en) 1977-09-01
NO761017L (en) 1976-10-12
HU175592B (en) 1980-09-28
ES446907A1 (en) 1977-09-16
DK150676A (en) 1976-10-12
IL49100A (en) 1979-03-12
IL49100A0 (en) 1976-04-30
GB1546898A (en) 1979-05-31
SE7602565L (en) 1976-10-12
DE2614669A1 (en) 1976-10-21
NL184258B (en) 1989-01-02
SU668608A3 (en) 1979-06-15
CS191970B2 (en) 1979-07-31
FI65069B (en) 1983-11-30
PL104803B1 (en) 1979-09-29
NO151748C (en) 1985-06-05
FI65069C (en) 1984-03-12
NO151748B (en) 1985-02-18
AU500013B2 (en) 1979-05-10
CA1045114A (en) 1978-12-26
ATA258476A (en) 1977-10-15
AR210880A1 (en) 1977-09-30
GR59912B (en) 1978-03-20
FR2306698A1 (en) 1976-11-05
OA05290A (en) 1981-02-28
CH621554A5 (en) 1981-02-13
NL184258C (en) 1989-06-01
JPS6110474B2 (en) 1986-03-29
FI760788A (en) 1976-10-12
JPS51123812A (en) 1976-10-28
ZA761103B (en) 1977-10-26
AT343806B (en) 1978-06-26
RO68501A (en) 1981-04-30
PT64917A (en) 1976-04-01
YU40643B (en) 1986-04-30
MX3687E (en) 1981-04-29
DK148022C (en) 1985-07-22
LU74740A1 (en) 1976-11-11
FR2306698B1 (en) 1979-10-05
PT64917B (en) 1977-08-24
US4006138A (en) 1977-02-01
DK148022B (en) 1985-02-04
DD125950A5 (en) 1977-06-01

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