SE401674B - Forfarande for framstellning av farmakologiskt aktiva bensocykloheptaisokinolinderivat samt syraadditionssalter derav - Google Patents
Forfarande for framstellning av farmakologiskt aktiva bensocykloheptaisokinolinderivat samt syraadditionssalter deravInfo
- Publication number
- SE401674B SE401674B SE7101475A SE147571A SE401674B SE 401674 B SE401674 B SE 401674B SE 7101475 A SE7101475 A SE 7101475A SE 147571 A SE147571 A SE 147571A SE 401674 B SE401674 B SE 401674B
- Authority
- SE
- Sweden
- Prior art keywords
- benzocycloheptaisochinoline
- derivatives
- procedure
- preparation
- pharmacologically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1030670A | 1970-02-10 | 1970-02-10 | |
| US097481A US3914305A (en) | 1970-02-10 | 1970-12-21 | N-{8 (10,11-dihydro-5H-dibenzo{8 a,d{9 cyclohepten-5-yl)methyl{9 amides |
| US510275A US3922346A (en) | 1970-02-10 | 1974-09-30 | Benzocycloheptaisoquinoline derivatives III in producing CNS depressant effects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE401674B true SE401674B (sv) | 1978-05-22 |
Family
ID=27359200
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7101475A SE401674B (sv) | 1970-02-10 | 1971-02-05 | Forfarande for framstellning av farmakologiskt aktiva bensocykloheptaisokinolinderivat samt syraadditionssalter derav |
| SE7315436A SE406195B (sv) | 1970-02-10 | 1973-11-14 | Forfarande for framstellning av bensocykloheptaisokinolinderivat samt syraadditionssalter derav |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7315436A SE406195B (sv) | 1970-02-10 | 1973-11-14 | Forfarande for framstellning av bensocykloheptaisokinolinderivat samt syraadditionssalter derav |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US3657250A (nl) |
| AR (4) | AR195768A1 (nl) |
| BE (1) | BE762595A (nl) |
| CA (1) | CA982124A (nl) |
| CH (3) | CH584201A5 (nl) |
| CS (1) | CS181207B2 (nl) |
| DE (1) | DE2106165A1 (nl) |
| DK (1) | DK139582B (nl) |
| FI (1) | FI49504C (nl) |
| FR (1) | FR2081498B1 (nl) |
| GB (1) | GB1341109A (nl) |
| NL (1) | NL170733C (nl) |
| SE (2) | SE401674B (nl) |
| ZA (1) | ZA71532B (nl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3896130A (en) * | 1972-08-04 | 1975-07-22 | Ayerst Mckenna & Harrison | Ocathydrobenzocycloheptapyridoisoquinoline derivatives and process for the preparation thereof |
| US4053604A (en) * | 1975-11-26 | 1977-10-11 | Ayerst, Mckenna & Harrison Limited | Method for improving anesthesia and compositions therefor |
| US4062851A (en) * | 1975-11-26 | 1977-12-13 | Ayerst Mckenna And Harrison Ltd. | Process for the resolution of certain octahydrobenzocycloheptapyridoisoquinolinols |
| US4059585A (en) * | 1976-07-27 | 1977-11-22 | Ayerst Mckenna And Harrison Ltd. | Process for preparing an intermediate for CNS depressants |
| FR2366839A2 (fr) * | 1976-10-08 | 1978-05-05 | Ayerst Mckenna & Harrison | Derives de benzocycloheptane-isoquinoleine |
| TWI375676B (en) * | 2005-08-29 | 2012-11-01 | Msd Oss Bv | Non-steroidal glucocorticoid receptor modulators |
| WO2017100623A1 (en) | 2015-12-09 | 2017-06-15 | Brandeis University | Dbh inhibitors for treating or preventing memory loss |
| CN109970626A (zh) * | 2018-12-30 | 2019-07-05 | 南京正荣医药化学有限公司 | 一种2-哌啶酮碱金属盐的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US336175A (en) * | 1886-02-16 | tompeins | ||
| US3052721A (en) * | 1961-01-10 | 1962-09-04 | Olin Mathieson | Dihydrodibenzocy cloheptene derivatives |
| US3403157A (en) * | 1965-09-01 | 1968-09-24 | American Home Prod | Benzo[6, 7]cyclohepta[1, 2, 3-d, e]isoquinoline derivatives |
-
1970
- 1970-02-10 US US10306A patent/US3657250A/en not_active Expired - Lifetime
- 1970-12-21 US US097481A patent/US3914305A/en not_active Expired - Lifetime
-
1971
- 1971-01-27 ZA ZA710532A patent/ZA71532B/xx unknown
- 1971-02-05 BE BE762595A patent/BE762595A/xx not_active IP Right Cessation
- 1971-02-05 SE SE7101475A patent/SE401674B/xx unknown
- 1971-02-05 FR FR7103970A patent/FR2081498B1/fr not_active Expired
- 1971-02-08 CH CH172574A patent/CH584201A5/xx not_active IP Right Cessation
- 1971-02-08 CH CH172674A patent/CH569716A5/xx not_active IP Right Cessation
- 1971-02-08 CH CH182271A patent/CH548395A/fr not_active IP Right Cessation
- 1971-02-09 DK DK57071AA patent/DK139582B/da unknown
- 1971-02-09 CS CS7100000935A patent/CS181207B2/cs unknown
- 1971-02-09 CA CA104,933A patent/CA982124A/en not_active Expired
- 1971-02-09 FI FI710353A patent/FI49504C/fi active
- 1971-02-10 AR AR233932A patent/AR195768A1/es active
- 1971-02-10 DE DE19712106165 patent/DE2106165A1/de not_active Ceased
- 1971-02-10 NL NLAANVRAGE7101752,A patent/NL170733C/nl active
- 1971-04-19 GB GB2142771A patent/GB1341109A/en not_active Expired
- 1971-12-01 AR AR239358A patent/AR195786A1/es active
- 1971-12-01 AR AR239357A patent/AR195785A1/es active
-
1972
- 1972-01-01 AR AR245635A patent/AR206589A1/es active
-
1973
- 1973-11-14 SE SE7315436A patent/SE406195B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR206589A1 (es) | 1976-08-06 |
| FI49504B (nl) | 1975-04-01 |
| AR195768A1 (es) | 1973-11-09 |
| US3657250A (en) | 1972-04-18 |
| DE2106165A1 (de) | 1971-08-19 |
| SE406195B (sv) | 1979-01-29 |
| BE762595A (fr) | 1971-08-05 |
| CS181207B2 (en) | 1978-03-31 |
| FI49504C (fi) | 1975-07-10 |
| CH584201A5 (nl) | 1977-01-31 |
| ZA71532B (en) | 1972-07-26 |
| DK139582C (nl) | 1979-09-03 |
| CH569716A5 (nl) | 1975-11-28 |
| FR2081498A1 (nl) | 1971-12-03 |
| NL170733C (nl) | 1982-12-16 |
| CA982124A (en) | 1976-01-20 |
| NL7101752A (nl) | 1971-08-12 |
| AR195786A1 (es) | 1973-11-09 |
| FR2081498B1 (nl) | 1975-01-17 |
| DK139582B (da) | 1979-03-12 |
| NL170733B (nl) | 1982-07-16 |
| GB1341109A (en) | 1973-12-19 |
| CH548395A (fr) | 1974-04-30 |
| US3914305A (en) | 1975-10-21 |
| AR195785A1 (es) | 1973-11-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO145883C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 7-methoxy-7-acylamino-cefalosporansyrederivater | |
| SE393800B (sv) | Forfarande for framstellning av bensoylamino-alkyl-fenoxi-alkylkarbonsyraderivat med lipidsenkande effekt | |
| SE409460B (sv) | Forfarande for framstellnoing av farmaceutiskt godtagbara syraadditionssalter av aminoglykosidantibiotika | |
| NO143575C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive prostansyre-derivater | |
| SE385885B (sv) | Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat | |
| SE405974B (sv) | Forfarande for framstellning av 5,10-imino-dibenso(a,d)cykloheptenderivat samt syraadditionssalter derav | |
| SE397677B (sv) | Forfarande for framstellning av en alfa-dipeptidlagalkylester av l-asparaginsyra | |
| SE385698B (sv) | Forfarande for framstellning av kinolinettiksyraderivat | |
| SE405477B (sv) | Forfarande for framstellning av tetrazolyl-kinaldinsyraderivat med farmakologisk verkan | |
| SE403911B (sv) | Forfarande for framstellning av aroylsubstituerade fenylettiksyraderivat med anti-inflammatorisk verkan | |
| SE401674B (sv) | Forfarande for framstellning av farmakologiskt aktiva bensocykloheptaisokinolinderivat samt syraadditionssalter derav | |
| SE400551B (sv) | Forfarande for framstellning av terapeutiskt aktiva 3-amino-5-karbamylbensoesyraderivat | |
| SE388199B (sv) | Forfarande for framstellning av estrar av 3-metylflavon-8-karbonsyra med aminoalkoholer samt syraadditionssalter av dessa estrar | |
| SE399708B (sv) | Forfarande for framstellning av tioxanton-2-karboxylsyraderivat | |
| SE380273B (sv) | Forfarande for framstellning av tiopyrimidinderivat | |
| SE393801B (sv) | Forfarande for framstellning av tiokarbaminsyraderivat med antifungistatisk lekemedelsverken | |
| SE385471B (sv) | Forfarande for framstellning av bensobicykloalkanaminer med analgetisk eller anti-inflammatorisk lekemedelsverkan | |
| NO139050C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive nororipavin- og tebainderivater | |
| SE384852B (sv) | Forfarande for framstellning av 2-(6-metoxi-2-naftyl) propionsyra | |
| SE392611B (sv) | Forfarande for framstellning av antrakinonkarboxylsyra | |
| SE380517B (sv) | Forfarande for framstellning av fluoren-2-ettiksyraderivat med antiinflammatorisk verkan | |
| SE401829B (sv) | Forfarande for framstellning av 5-fenyl-6,7-bensomorfanderivat och salter derav | |
| SE388195B (sv) | Forfarande for framstellning av 2,5-dihydroxibensensulfonsyraderivat med hemostatisk hypokolesterolemisk, hypotriglyceridemisk och hypolipemisk verkan | |
| NO137998C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive tebain- og oripavin-derivater | |
| SE385887B (sv) | Forfarande for framstellning av 5-substituerad-5-fenylalkylbarbitursyra med analgetisk verkan |