SE336578B - - Google Patents
Info
- Publication number
- SE336578B SE336578B SE03592/67A SE359267A SE336578B SE 336578 B SE336578 B SE 336578B SE 03592/67 A SE03592/67 A SE 03592/67A SE 359267 A SE359267 A SE 359267A SE 336578 B SE336578 B SE 336578B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- reacting
- resulting
- halide
- group
- Prior art date
Links
- -1 10 - substituted - dibenzo[a,d]cyclohepten-5-one Chemical class 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 4
- 150000002576 ketones Chemical class 0.000 abstract 4
- 229910052751 metal Inorganic materials 0.000 abstract 4
- 239000002184 metal Substances 0.000 abstract 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000000047 product Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001298 alcohols Chemical class 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 230000018044 dehydration Effects 0.000 abstract 2
- 238000006297 dehydration reaction Methods 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910001507 metal halide Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NNSCWLNBQBCFAZ-UHFFFAOYSA-N 2-(3-aminoprop-1-ynyl)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ol Chemical compound OC1(C2=C(C=CC3=C1C=CC=C3)C=CC=C2)C#CCN NNSCWLNBQBCFAZ-UHFFFAOYSA-N 0.000 abstract 1
- YRRIUDVLNTXOTL-UHFFFAOYSA-N 3-benzyltricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,9,11,13-heptaen-8-one Chemical compound C(C1=CC=CC=C1)C1=CC=CC=2C(C=CC3=C(C21)C=CC=C3)=O YRRIUDVLNTXOTL-UHFFFAOYSA-N 0.000 abstract 1
- WYAFINWXANSYGR-UHFFFAOYSA-N 5-bromodibenzo[1,2-a:1',2'-e][7]annulen-11-one Chemical compound BrC1=CC2=CC=CC=C2C(=O)C2=CC=CC=C12 WYAFINWXANSYGR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- ZXIJMRYMVAMXQP-UHFFFAOYSA-N cycloheptene Chemical compound C1CCC=CCC1 ZXIJMRYMVAMXQP-UHFFFAOYSA-N 0.000 abstract 1
- 230000020335 dealkylation Effects 0.000 abstract 1
- 238000006900 dealkylation reaction Methods 0.000 abstract 1
- 150000008508 dibenzocycloheptenes Chemical class 0.000 abstract 1
- 125000001033 ether group Chemical group 0.000 abstract 1
- 125000004969 haloethyl group Chemical group 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- JKANAVGODYYCQF-UHFFFAOYSA-N prop-2-yn-1-amine Chemical compound NCC#C JKANAVGODYYCQF-UHFFFAOYSA-N 0.000 abstract 1
- TVDSBUOJIPERQY-UHFFFAOYSA-N prop-2-yn-1-ol Chemical compound OCC#C TVDSBUOJIPERQY-UHFFFAOYSA-N 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
- C07C13/28—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
- C07C13/32—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings
- C07C13/54—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with three condensed rings
- C07C13/547—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with three condensed rings at least one ring not being six-membered, the other rings being at the most six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/31—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by at least three rings
- C07C211/32—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by at least three rings containing dibenzocycloheptane or dibenzocycloheptene ring systems or condensed derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH390466A CH471772A (de) | 1966-03-17 | 1966-03-17 | Verfahren zur Herstellung von tricyclischen Aminen |
| CH240869A CH472363A (de) | 1966-03-17 | 1966-03-17 | Verfahren zur Herstellung von tricyclischen Aminen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE336578B true SE336578B (en:Method) | 1971-07-12 |
Family
ID=25690378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE03592/67A SE336578B (en:Method) | 1966-03-17 | 1967-03-15 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3527806A (en:Method) |
| BE (1) | BE695447A (en:Method) |
| CH (2) | CH471772A (en:Method) |
| DE (1) | DE1618491A1 (en:Method) |
| FR (2) | FR7193M (en:Method) |
| GB (1) | GB1163969A (en:Method) |
| IL (1) | IL27555A (en:Method) |
| NL (1) | NL6702913A (en:Method) |
| SE (1) | SE336578B (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3917669A (en) * | 1966-11-08 | 1975-11-04 | Hoffmann La Roche | Intermediates for tricyclic amines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3409640A (en) * | 1959-07-22 | 1968-11-05 | Schering Corp | 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes |
| NL293802A (en:Method) * | 1962-06-07 | |||
| CH494730A (de) * | 1963-07-25 | 1970-08-15 | Merck & Co Inc | Verfahren zur Herstellung von Dibenzocyclopentenen |
-
1966
- 1966-03-17 CH CH390466A patent/CH471772A/de not_active IP Right Cessation
- 1966-03-17 CH CH240869A patent/CH472363A/de not_active IP Right Cessation
-
1967
- 1967-02-09 DE DE19671618491 patent/DE1618491A1/de active Pending
- 1967-02-24 NL NL6702913A patent/NL6702913A/xx unknown
- 1967-03-03 US US620241A patent/US3527806A/en not_active Expired - Lifetime
- 1967-03-08 IL IL27555A patent/IL27555A/en unknown
- 1967-03-10 FR FR98214A patent/FR7193M/fr not_active Expired
- 1967-03-14 BE BE695447D patent/BE695447A/xx unknown
- 1967-03-15 SE SE03592/67A patent/SE336578B/xx unknown
- 1967-03-16 FR FR98992A patent/FR1516519A/fr not_active Expired
- 1967-03-16 GB GB02324/67A patent/GB1163969A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3527806A (en) | 1970-09-08 |
| FR1516519A (fr) | 1968-03-08 |
| GB1163969A (en) | 1969-09-10 |
| BE695447A (en:Method) | 1967-08-14 |
| CH471772A (de) | 1969-04-30 |
| FR7193M (en:Method) | 1969-08-18 |
| NL6702913A (en:Method) | 1967-09-18 |
| CH472363A (de) | 1969-05-15 |
| IL27555A (en) | 1972-06-28 |
| DE1618491A1 (de) | 1970-10-29 |
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