SE1850840A1 - A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance - Google Patents

A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance

Info

Publication number
SE1850840A1
SE1850840A1 SE1850840A SE1850840A SE1850840A1 SE 1850840 A1 SE1850840 A1 SE 1850840A1 SE 1850840 A SE1850840 A SE 1850840A SE 1850840 A SE1850840 A SE 1850840A SE 1850840 A1 SE1850840 A1 SE 1850840A1
Authority
SE
Sweden
Prior art keywords
module
light
sensor
optical fiber
biosensor system
Prior art date
Application number
SE1850840A
Inventor
Daniel Aili
Erik Martinsson
Ingemar Lundström
Original Assignee
Arguseye Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arguseye Ab filed Critical Arguseye Ab
Priority to SE1850840A priority Critical patent/SE1850840A1/en
Priority to PCT/SE2019/050626 priority patent/WO2020009642A1/en
Priority to EP19737267.5A priority patent/EP3818360A1/en
Publication of SE1850840A1 publication Critical patent/SE1850840A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N2021/8411Application to online plant, process monitoring

Abstract

The present invention relates to an online biosensor system and method for combined real-time UV-light monitoring and nanoplasmonic sensing based on LSPR. The biosensor system comprises a sensor module, a light source module, optical fiber module and a detector module. The sensor module comprises at least one sensor chip which is contact with a sample. A first sensor chip of the sensor module comprises a surface and plasmonic nanoparticles. The plasmonic nanoparticles are immobilized on said surface or alternatively on an optional substrate configured above said surface. The nanoparticles capture molecules, such as the antibodies, and said molecules have specificity for one or more analytes. The light source module emits a first light in the UV light region as well as a second light in the visible region or in the near-infrared region. The optical fiber module comprises at least one optical fiber which is connected to the sensor module, light source module and the detector module. The optical fiber module passes light from the light source module to the sensor module. Moreover, the optical fiber module also passes reflected or transmitted light from the sensor module directly or indirectly to the detector module. The detector module detects reflected or transmitted UV light and LSPR shift from said sensor module.
SE1850840A 2018-07-03 2018-07-03 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance SE1850840A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE1850840A SE1850840A1 (en) 2018-07-03 2018-07-03 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance
PCT/SE2019/050626 WO2020009642A1 (en) 2018-07-03 2019-06-27 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance
EP19737267.5A EP3818360A1 (en) 2018-07-03 2019-06-27 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1850840A SE1850840A1 (en) 2018-07-03 2018-07-03 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance

Publications (1)

Publication Number Publication Date
SE1850840A1 true SE1850840A1 (en) 2020-01-04

Family

ID=67211795

Family Applications (1)

Application Number Title Priority Date Filing Date
SE1850840A SE1850840A1 (en) 2018-07-03 2018-07-03 A real-time online biosensor system for combined uv-light detection and nanoplasmonic sensing using localized surface plasmon resonance

Country Status (3)

Country Link
EP (1) EP3818360A1 (en)
SE (1) SE1850840A1 (en)
WO (1) WO2020009642A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2919086B2 (en) * 2022-06-28 2023-06-22 Fibsen Monitorizaciones S L MODULABLE MULTIPARAMETRIC PROBE FOR FIBER OPTIC SENSORS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014139031A1 (en) * 2013-03-15 2014-09-18 Concordia University Methods for fabricating morphologically transformed nano-structures (mtns) and tunable nanocomposite polymer materials, and devices using such materials

Also Published As

Publication number Publication date
WO2020009642A1 (en) 2020-01-09
EP3818360A1 (en) 2021-05-12

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