SE0203746D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE0203746D0 SE0203746D0 SE0203746A SE0203746A SE0203746D0 SE 0203746 D0 SE0203746 D0 SE 0203746D0 SE 0203746 A SE0203746 A SE 0203746A SE 0203746 A SE0203746 A SE 0203746A SE 0203746 D0 SE0203746 D0 SE 0203746D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compounds
- compounds
- tetrahydronaphtalenes
- acromegaly
- igf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention refers to new compounds belonging to the group of substituted 1-phenyl-tetrahydronaphtalenes and the use thereof as inhibitors of the insulin-like growth factor-1 receptor. Said compounds can be used for treatment of IGF-1R dependent diseases, such as cancer, psoriasis, arteriosclerosis and acromegaly.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0203746A SE0203746D0 (en) | 2002-12-18 | 2002-12-18 | New compounds |
PCT/SE2003/002010 WO2004054996A1 (en) | 2002-12-18 | 2003-12-18 | New substituted 1-phenyl-tetrahydronaphtalene derivatives and their use as inhibitors of igf-1 receptor |
AU2003288857A AU2003288857A1 (en) | 2002-12-18 | 2003-12-18 | New substituted 1-phenyl-tetrahydronaphtalene derivatives and their use as inhibitors of igf-1 receptor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0203746A SE0203746D0 (en) | 2002-12-18 | 2002-12-18 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0203746D0 true SE0203746D0 (en) | 2002-12-18 |
Family
ID=20289899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0203746A SE0203746D0 (en) | 2002-12-18 | 2002-12-18 | New compounds |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2003288857A1 (en) |
SE (1) | SE0203746D0 (en) |
WO (1) | WO2004054996A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2621820A1 (en) * | 2005-09-09 | 2007-03-15 | Jan Gunzinger | Isoquinolines derivatives as igf-1r inhibitors |
JP2009507819A (en) | 2005-09-09 | 2009-02-26 | アナリットコン エス アー | Isoquinoline as an IGF-1R inhibitor |
WO2009100349A1 (en) | 2008-02-09 | 2009-08-13 | The Trustees Of Columbia University In The City Of New York | Analogues of (-)-picropodophyllin, synthesis and uses thereof |
WO2011083391A2 (en) | 2010-01-05 | 2011-07-14 | Pfizer Inc. | Biomarkers for anti-igf-ir cancer therapy |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0207124B1 (en) * | 1984-12-28 | 1991-10-09 | Conpharm Ab | Use of podophyllotoxin and derivatives thereof |
SE0102168D0 (en) * | 2001-06-19 | 2001-06-19 | Karolinska Innovations Ab | New use and new compounds |
-
2002
- 2002-12-18 SE SE0203746A patent/SE0203746D0/en unknown
-
2003
- 2003-12-18 WO PCT/SE2003/002010 patent/WO2004054996A1/en not_active Application Discontinuation
- 2003-12-18 AU AU2003288857A patent/AU2003288857A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2003288857A1 (en) | 2004-07-09 |
WO2004054996A1 (en) | 2004-07-01 |
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