SE0201881D0 - Novel compounds, their use, and preparation - Google Patents

Novel compounds, their use, and preparation

Info

Publication number
SE0201881D0
SE0201881D0 SE0201881A SE0201881A SE0201881D0 SE 0201881 D0 SE0201881 D0 SE 0201881D0 SE 0201881 A SE0201881 A SE 0201881A SE 0201881 A SE0201881 A SE 0201881A SE 0201881 D0 SE0201881 D0 SE 0201881D0
Authority
SE
Sweden
Prior art keywords
preparation
relates
present
compound
compounds
Prior art date
Application number
SE0201881A
Other languages
Swedish (sv)
Inventor
Bjoern Nilsson
Erik Ringberg
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Priority to SE0201881A priority Critical patent/SE0201881D0/en
Publication of SE0201881D0 publication Critical patent/SE0201881D0/en
Priority to PT05023471T priority patent/PT1645558E/en
Priority to IL16522003A priority patent/IL165220A0/en
Priority to ES03736405T priority patent/ES2270051T3/en
Priority to MXPA04012711A priority patent/MXPA04012711A/en
Priority to DE60330864T priority patent/DE60330864D1/en
Priority to ES05023471T priority patent/ES2307102T3/en
Priority to EP03736405A priority patent/EP1529043B1/en
Priority to DK05023471T priority patent/DK1645558T3/en
Priority to JP2004530934A priority patent/JP4592417B2/en
Priority to SI200330493T priority patent/SI1529043T1/en
Priority to CA002485537A priority patent/CA2485537A1/en
Priority to PCT/SE2003/001044 priority patent/WO2004000830A1/en
Priority to CN 200610132184 priority patent/CN100999501A/en
Priority to CA2723494A priority patent/CA2723494C/en
Priority to US10/464,422 priority patent/US7226925B2/en
Priority to DK03736405T priority patent/DK1529043T3/en
Priority to DE60307286T priority patent/DE60307286T2/en
Priority to EP03760997A priority patent/EP1513831B1/en
Priority to AT05023471T priority patent/ATE398119T1/en
Priority to PCT/SE2003/001043 priority patent/WO2004000829A1/en
Priority to DE60321606T priority patent/DE60321606D1/en
Priority to EP05023471A priority patent/EP1645558B1/en
Priority to AU2003237746A priority patent/AU2003237746B8/en
Priority to CNB038141310A priority patent/CN100484933C/en
Priority to CNB038141612A priority patent/CN100334082C/en
Priority to CA2485532A priority patent/CA2485532C/en
Priority to BR0311970-0A priority patent/BR0311970A/en
Priority to PT03736405T priority patent/PT1529043E/en
Priority to AT03760997T priority patent/ATE454383T1/en
Priority to NZ536663A priority patent/NZ536663A/en
Priority to NZ536664A priority patent/NZ536664A/en
Priority to JP2004530935A priority patent/JP4460450B2/en
Priority to EA200500045A priority patent/EA008148B1/en
Priority to AU2003243089A priority patent/AU2003243089B2/en
Priority to US10/464,181 priority patent/US7129354B2/en
Priority to SI200331283T priority patent/SI1645558T1/en
Priority to AT03736405T priority patent/ATE334980T1/en
Priority to ZA200409277A priority patent/ZA200409277B/en
Priority to NO20050270A priority patent/NO20050270L/en
Priority to NO20050279A priority patent/NO20050279D0/en
Priority to HK05111675.4A priority patent/HK1079526A1/en
Priority to HK06100135.0A priority patent/HK1080079B/en
Priority to US11/359,152 priority patent/US7820677B2/en
Priority to CY20061101556T priority patent/CY1106225T1/en
Priority to JP2010002229A priority patent/JP5378241B2/en
Priority to US12/817,833 priority patent/US8030316B2/en
Priority to US13/234,510 priority patent/US20120004241A1/en
Priority to US13/234,555 priority patent/US8410113B2/en
Priority to JP2013019444A priority patent/JP2013116906A/en
Priority to US13/768,641 priority patent/US8835439B2/en
Priority to JP2013142942A priority patent/JP2013227336A/en
Priority to US14/274,131 priority patent/US20140329826A1/en

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I). The invention also relates to (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride and a process for preparing the same. Another object of the present invention is a compound of the formula (I). Another object of the present invention is a method for the treatment or prophylaxis of a serotonin-related disorder, comprising administering to a subject in need thereof an effective amount of the compound above; as well as the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
SE0201881A 2002-06-19 2002-06-19 Novel compounds, their use, and preparation SE0201881D0 (en)

Priority Applications (53)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (en) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation
PT05023471T PT1645558E (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as serotonin 5-ht2c receptor modulators
IL16522003A IL165220A0 (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation
ES03736405T ES2270051T3 (en) 2002-06-19 2003-06-18 PROCEDURE FOR THE PREPARATION OF 2-METHYLIPIPERAZINE DERIVATIVES.
MXPA04012711A MXPA04012711A (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation.
DE60330864T DE60330864D1 (en) 2002-06-19 2003-06-18 NEW CONNECTIONS, THEIR USE AND MANUFACTURE
ES05023471T ES2307102T3 (en) 2002-06-19 2003-06-18 PIPERAZINILPIRAZINAS AS MODULATORS OF THE SEROTONINE 5-HT2C RECEPTOR.
EP03736405A EP1529043B1 (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives.
DK05023471T DK1645558T3 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines such as serotonin 5-HT2C receptor modulators
JP2004530934A JP4592417B2 (en) 2002-06-19 2003-06-18 New method
SI200330493T SI1529043T1 (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives.
CA002485537A CA2485537A1 (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation
PCT/SE2003/001044 WO2004000830A1 (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation
CN 200610132184 CN100999501A (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives
CA2723494A CA2723494C (en) 2002-06-19 2003-06-18 2-methyl piperazine derivatives for treatment of serotonin-related disorders
US10/464,422 US7226925B2 (en) 2002-06-19 2003-06-18 Compounds, their use and preparation
DK03736405T DK1529043T3 (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methylpiperazine derivatives
DE60307286T DE60307286T2 (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives.
EP03760997A EP1513831B1 (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation
AT05023471T ATE398119T1 (en) 2002-06-19 2003-06-18 PIPERAZINYLPYRAZINE AS MODULATORS OF THE SEROTONIN 5-HT2C RECEPTOR
PCT/SE2003/001043 WO2004000829A1 (en) 2002-06-19 2003-06-18 Novel process
DE60321606T DE60321606D1 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as modulators of the serotonin 5-HT2C receptor
EP05023471A EP1645558B1 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as serotonin 5-HT2C receptor modulators
AU2003237746A AU2003237746B8 (en) 2002-06-19 2003-06-18 Novel process
CNB038141310A CN100484933C (en) 2002-06-19 2003-06-18 Novel pyrazine compounds, their use in preparing medicament for treating diseases correlated with serotonin
CNB038141612A CN100334082C (en) 2002-06-19 2003-06-18 Novel process
CA2485532A CA2485532C (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives
BR0311970-0A BR0311970A (en) 2002-06-19 2003-06-18 New compounds, their use and preparation
PT03736405T PT1529043E (en) 2002-06-19 2003-06-18 Process for the preparation of 2-methyl piperazine derivatives.
AT03760997T ATE454383T1 (en) 2002-06-19 2003-06-18 NEW COMPOUNDS, THEIR USE AND PRODUCTION
NZ536663A NZ536663A (en) 2002-06-19 2003-06-18 Process for the preparation of pharmaceutically acceptable salts of selective piperazinyl 5-HT2c receptor ligands
NZ536664A NZ536664A (en) 2002-06-19 2003-06-18 Piperazinylpyrazine derivative compounds, their use and preparation
JP2004530935A JP4460450B2 (en) 2002-06-19 2003-06-18 Novel compounds, their use and production
EA200500045A EA008148B1 (en) 2002-06-19 2003-06-18 New compounds, their use and preparation
AU2003243089A AU2003243089B2 (en) 2002-06-19 2003-06-18 Novel compounds, their use and preparation
US10/464,181 US7129354B2 (en) 2002-06-19 2003-06-18 Process for the preparation of stable acid addition salt of 2,3-disubstituted pyrazine compounds
SI200331283T SI1645558T1 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as serotonin 5-HT2C receptor modulators
AT03736405T ATE334980T1 (en) 2002-06-19 2003-06-18 METHOD FOR PRODUCING 2-METHYL PIPERAZINE DERIVATIVES.
ZA200409277A ZA200409277B (en) 2002-06-19 2004-11-18 Novel compounds, their use and preparation.
NO20050270A NO20050270L (en) 2002-06-19 2005-01-17 New compounds, their use and manufacture
NO20050279A NO20050279D0 (en) 2002-06-19 2005-01-18 New procedure
HK05111675.4A HK1079526A1 (en) 2002-06-19 2005-12-19 A novel pyrazine compound and its use in the manufacture of a medicament for treating diseases related to serotonin
HK06100135.0A HK1080079B (en) 2002-06-19 2006-01-04 A process for the preparation of 2-methylpiperazine derivative
US11/359,152 US7820677B2 (en) 2002-06-19 2006-02-22 Phosphoric acid addition salt of (2R)-1-[3-(2-{[2-(2-dimethylaminoethoxy)-3-pyridinyl]oxy}-ethoxy)-2-pyrazinyl]-2-methylpiperazine
CY20061101556T CY1106225T1 (en) 2002-06-19 2006-10-30 PROCEDURE FOR THE PREPARATION OF 2-METHYL PIPEZINE
JP2010002229A JP5378241B2 (en) 2002-06-19 2010-01-07 Therapeutic compound
US12/817,833 US8030316B2 (en) 2002-06-19 2010-06-17 Malate salt of (2R)-methyl-1-{3-[2-(3-pyridinyloxy)ethoxy]-2-pyrazinyl}piperazine
US13/234,510 US20120004241A1 (en) 2002-06-19 2011-09-16 Succinate salt of (2r)-methyl-1-piperazine
US13/234,555 US8410113B2 (en) 2002-06-19 2011-09-16 (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine and salts thereof
JP2013019444A JP2013116906A (en) 2002-06-19 2013-02-04 Novel process
US13/768,641 US8835439B2 (en) 2002-06-19 2013-02-15 Pharmaceutical composition containing (2R)-methyl-1-3-[2-(3-pyridinyloxy)ethoxy]-2-pyrazinylpiperazine L-malate for treatment of serotonin-related diseases
JP2013142942A JP2013227336A (en) 2002-06-19 2013-07-08 Novel process
US14/274,131 US20140329826A1 (en) 2002-06-19 2014-05-09 (2r)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine and salts thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (en) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation

Publications (1)

Publication Number Publication Date
SE0201881D0 true SE0201881D0 (en) 2002-06-19

Family

ID=20288241

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0201881A SE0201881D0 (en) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation

Country Status (3)

Country Link
CN (1) CN100999501A (en)
SE (1) SE0201881D0 (en)
ZA (1) ZA200409277B (en)

Also Published As

Publication number Publication date
CN100999501A (en) 2007-07-18
ZA200409277B (en) 2006-01-25

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