SE0100374D0 - Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof - Google Patents

Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof

Info

Publication number
SE0100374D0
SE0100374D0 SE0100374A SE0100374A SE0100374D0 SE 0100374 D0 SE0100374 D0 SE 0100374D0 SE 0100374 A SE0100374 A SE 0100374A SE 0100374 A SE0100374 A SE 0100374A SE 0100374 D0 SE0100374 D0 SE 0100374D0
Authority
SE
Sweden
Prior art keywords
novel compositions
inhibitors
protein kinase
potassium channel
channel openers
Prior art date
Application number
SE0100374A
Other languages
Swedish (sv)
Inventor
Jan Rundegren
Bo Kreilgaard
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE0100374A priority Critical patent/SE0100374D0/en
Publication of SE0100374D0 publication Critical patent/SE0100374D0/en
Priority to JP2002562427A priority patent/JP2004518701A/en
Priority to EP02715944A priority patent/EP1357974A1/en
Priority to PCT/SE2002/000105 priority patent/WO2002062422A1/en
Priority to US10/059,658 priority patent/US20020137692A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Abstract

Novel compositions comprising one or more potassium channel openers, such as minoxidil, and one or more protein kinase C inhibitors, such as procyanidin B2. Also presented are methods for using the novel compositions for treating and preventing hair loss in a region of a patient.
SE0100374A 2001-02-07 2001-02-07 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof SE0100374D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE0100374A SE0100374D0 (en) 2001-02-07 2001-02-07 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof
JP2002562427A JP2004518701A (en) 2001-02-07 2002-01-23 Novel compositions of potassium channel openers and protein kinase C inhibitors and uses thereof
EP02715944A EP1357974A1 (en) 2001-02-07 2002-01-23 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof
PCT/SE2002/000105 WO2002062422A1 (en) 2001-02-07 2002-01-23 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof
US10/059,658 US20020137692A1 (en) 2001-02-07 2002-01-29 Novel compositions of potassium channel openers and protein kinase C inhibitors and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0100374A SE0100374D0 (en) 2001-02-07 2001-02-07 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof

Publications (1)

Publication Number Publication Date
SE0100374D0 true SE0100374D0 (en) 2001-02-07

Family

ID=20282870

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0100374A SE0100374D0 (en) 2001-02-07 2001-02-07 Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof

Country Status (4)

Country Link
EP (1) EP1357974A1 (en)
JP (1) JP2004518701A (en)
SE (1) SE0100374D0 (en)
WO (1) WO2002062422A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070208087A1 (en) 2001-11-02 2007-09-06 Sanders Virginia J Compounds, compositions and methods for the treatment of inflammatory diseases
ES2447417T3 (en) 2002-05-31 2014-03-12 Proteotech, Inc. Compounds, compositions and methods for the treatment of amyloidosis and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease
EP1921076A1 (en) * 2002-10-11 2008-05-14 Proteotech Inc. systhesis of procyanidin B2
EP1554270A2 (en) * 2002-10-11 2005-07-20 Proteotech, Inc. Isolation, purification and synthesis of procyanidin b2 and uses thereof
JP2012504135A (en) * 2008-09-27 2012-02-16 ジャイナ ファーマシューティカルズ，インコーポレーテッド Lipid-based pharmaceutical preparations for oral and topical application, and compositions, methods and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596812A (en) * 1976-05-24 1986-06-24 The Upjohn Company Methods and solutions for treating male pattern alopecia
DK0542802T3 (en) * 1990-08-10 1996-07-22 Upjohn Co Stimulation of hair growth with potassium channel openers and 5alpha reductase inhibitors
AU686691B2 (en) * 1994-01-12 1998-02-12 F. Hoffmann-La Roche Ag Novel azepanes and homologs thereof
EP0768079B1 (en) * 1994-06-30 2003-05-28 Kyowa Hakko Kogyo Co., Ltd. Hair growth stimulant
TW339325B (en) * 1995-07-05 1998-09-01 Hoffmann La Roche Novel azepane derivatives, process for the preparation thereof and pharmaceutical composition containing the same
KR100499190B1 (en) * 1996-03-29 2006-04-17 교와 핫꼬 고교 가부시끼가이샤 Hair restorer

Also Published As

Publication number Publication date
JP2004518701A (en) 2004-06-24
EP1357974A1 (en) 2003-11-05
WO2002062422A1 (en) 2002-08-15

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