RU99121654A - MEANS FOR THE PREVENTION OR TREATMENT OF DISEASES ASSOCIATED WITH EXTREME PROLIFERATION OF EPITHELIAL PIGMENTAL RETAIN CELLS - Google Patents
MEANS FOR THE PREVENTION OR TREATMENT OF DISEASES ASSOCIATED WITH EXTREME PROLIFERATION OF EPITHELIAL PIGMENTAL RETAIN CELLSInfo
- Publication number
- RU99121654A RU99121654A RU99121654/14A RU99121654A RU99121654A RU 99121654 A RU99121654 A RU 99121654A RU 99121654/14 A RU99121654/14 A RU 99121654/14A RU 99121654 A RU99121654 A RU 99121654A RU 99121654 A RU99121654 A RU 99121654A
- Authority
- RU
- Russia
- Prior art keywords
- diseases associated
- prevention
- treatment
- epithelial
- pigmental
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title claims 6
- 230000035755 proliferation Effects 0.000 title claims 6
- 230000002265 prevention Effects 0.000 title claims 5
- 210000004694 pigment cell Anatomy 0.000 claims 5
- NZHGWWWHIYHZNX-UHFFFAOYSA-N 2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)benzoic acid Chemical compound C1=C(OC)C(OC)=CC=C1C=CC(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-UHFFFAOYSA-N 0.000 claims 4
- 210000001525 Retina Anatomy 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 239000011780 sodium chloride Substances 0.000 claims 4
- 229940012356 Eye Drops Drugs 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 229930002945 all-trans-retinaldehyde Natural products 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 239000003885 eye ointment Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002207 retinal Effects 0.000 claims 1
- 235000020945 retinal Nutrition 0.000 claims 1
- 239000011604 retinal Substances 0.000 claims 1
Claims (5)
или ее фармацевтически приемлемую соль.1. Agent for the prevention or treatment of diseases associated with excessive proliferation of epithelial pigment cells of the retina, comprising as an active ingredient N- (3,4-dimethoxycinnamoyl) anthranilic acid of the formula:
or its pharmaceutically acceptable salt.
или ее фармацевтически приемлемой соли.3. The method of prevention or treatment of diseases associated with excessive proliferation of epithelial pigment cells of the retina, including the introduction of N- (3,4-dimethoxycinnamoyl) anthranilic acid of the formula:
or its pharmaceutically acceptable salt.
или ее фармацевтически приемлемой соли для изготовления фармацевтической композиции для предупреждения или лечения болезней, связанных с чрезмерной пролиферацией эпителиальных пигментных клеток сетчатки.4. The use of N- (3,4-dimethoxycinnamoyl) anthranilic acid of the formula:
or its pharmaceutically acceptable salt for the manufacture of a pharmaceutical composition for the prevention or treatment of diseases associated with excessive proliferation of epithelial pigment cells of the retina.
или ее фармацевтически приемлемой соли в качестве средства для предупреждения или лечения болезней, связанных с чрезмерной пролиферацией эпителиальных пигментных клеток сетчатки.5. The use of N- (3,4-dimethoxycinnamoyl) anthranilic acid of the formula:
or a pharmaceutically acceptable salt thereof as a means to prevent or treat diseases associated with excessive proliferation of retinal epithelial pigment cells.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9/135675 | 1997-04-18 | ||
| JP13567597 | 1997-04-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU99121654A true RU99121654A (en) | 2001-08-20 |
| RU2207852C2 RU2207852C2 (en) | 2003-07-10 |
Family
ID=15157309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU99121654/14A RU2207852C2 (en) | 1997-04-18 | 1998-04-10 | Agents for prophylaxis or treatment of diseases associated with abnormal proliferation of retina epithelial pigment cells |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6303655B1 (en) |
| EP (1) | EP1008347A4 (en) |
| KR (1) | KR20010006485A (en) |
| CN (1) | CN1252718A (en) |
| AU (1) | AU6748398A (en) |
| CA (1) | CA2286120A1 (en) |
| IL (1) | IL132391A0 (en) |
| NZ (1) | NZ500300A (en) |
| RU (1) | RU2207852C2 (en) |
| WO (1) | WO1998047504A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002363075A (en) * | 2001-06-05 | 2002-12-18 | Kao Corp | Preventive and treating agent for hypertension |
| US20050106230A1 (en) * | 2003-11-17 | 2005-05-19 | Young Janel E. | Drug-enhanced adhesion prevention |
| AU2012200202B2 (en) * | 2004-03-10 | 2013-09-05 | Ethicon, Inc. | Drug-enhanced adhesion prevention |
| WO2006073126A1 (en) * | 2005-01-06 | 2006-07-13 | Kissei Pharmaceutical Co., Ltd. | Preventive and remedy for dry eye associated with chronic graft versus host disease |
| JP2010518014A (en) | 2007-01-31 | 2010-05-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | 2-Aminopyridine derivatives useful as kinase inhibitors |
| CN102131809A (en) | 2008-07-23 | 2011-07-20 | 沃泰克斯药物股份有限公司 | Tri-cyclic pyrazolopyridine kinase inhibitors |
| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| EP2318407B1 (en) | 2008-07-23 | 2013-01-02 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridine kinase inhibitors |
| WO2010017350A1 (en) | 2008-08-06 | 2010-02-11 | Vertex Pharmaceuticals Incorporated | Aminopyridine kinase inhibitors |
| EP2200412A1 (en) * | 2008-12-17 | 2010-06-23 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Flexible electronic product and method for manufacturing the same |
| WO2010129668A1 (en) | 2009-05-06 | 2010-11-11 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridines |
| WO2011094288A1 (en) | 2010-01-27 | 2011-08-04 | Vertex Pharmaceuticals Incorporated | Pyrazolopyrazine kinase inhibitors |
| MX2012008643A (en) | 2010-01-27 | 2013-02-26 | Vertex Pharma | Pyrazolopyrimidine kinase inhibitors. |
| CA2787315A1 (en) | 2010-01-27 | 2011-08-04 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridine kinase inhibitors |
| BR112022024728A2 (en) * | 2020-06-05 | 2023-03-07 | Occurx Pty Ltd | COMPOUNDS AND METHODS FOR TREATMENT OF OPHTHALMOLOGICAL DISORDERS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07116029B2 (en) * | 1989-04-04 | 1995-12-13 | キッセイ薬品工業株式会社 | Tranilast aqueous solution formulation |
| JP2617407B2 (en) * | 1992-09-14 | 1997-06-04 | キッセイ薬品工業株式会社 | Preventive and therapeutic agent for intimal cell hyperproliferative disease |
| CN1211182A (en) * | 1996-02-15 | 1999-03-17 | 橘生药品工业株式会社 | Neovascularization inhibitor |
| JPH09278653A (en) * | 1996-04-05 | 1997-10-28 | Santen Pharmaceut Co Ltd | Retinal disease-treating preparation |
| EP0950409B1 (en) * | 1996-09-28 | 2003-04-02 | Kissei Pharmaceutical Co. Ltd. | Subepithelial turbidity inhibitor |
| CA2267320A1 (en) * | 1996-10-14 | 1998-04-23 | Hiroshi Miyata | Secondary cataract inhibitor |
| BR9807330A (en) * | 1997-02-14 | 2000-04-18 | Kissei Pharmaceutical | Agents that inhibit pterygium progress and postoperative recurrence |
-
1998
- 1998-04-10 EP EP98912755A patent/EP1008347A4/en not_active Withdrawn
- 1998-04-10 WO PCT/JP1998/001654 patent/WO1998047504A1/en not_active Application Discontinuation
- 1998-04-10 RU RU99121654/14A patent/RU2207852C2/en not_active IP Right Cessation
- 1998-04-10 CN CN98804256A patent/CN1252718A/en active Pending
- 1998-04-10 KR KR1019997009575A patent/KR20010006485A/en not_active Application Discontinuation
- 1998-04-10 US US09/403,010 patent/US6303655B1/en not_active Expired - Fee Related
- 1998-04-10 AU AU67483/98A patent/AU6748398A/en not_active Abandoned
- 1998-04-10 CA CA002286120A patent/CA2286120A1/en not_active Abandoned
- 1998-04-10 IL IL13239198A patent/IL132391A0/en unknown
- 1998-04-10 NZ NZ500300A patent/NZ500300A/en unknown
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