RU99120946A - METHOD FOR DIAGNOSTIC OF IMMUNO DEFICIENCY STATE - Google Patents
METHOD FOR DIAGNOSTIC OF IMMUNO DEFICIENCY STATEInfo
- Publication number
- RU99120946A RU99120946A RU99120946/14A RU99120946A RU99120946A RU 99120946 A RU99120946 A RU 99120946A RU 99120946/14 A RU99120946/14 A RU 99120946/14A RU 99120946 A RU99120946 A RU 99120946A RU 99120946 A RU99120946 A RU 99120946A
- Authority
- RU
- Russia
- Prior art keywords
- indicator
- prt
- pot
- cells
- less
- Prior art date
Links
- 206010061598 Immunodeficiency Diseases 0.000 title claims 3
- 210000001744 T-Lymphocytes Anatomy 0.000 claims 3
- 108010044279 T-activin Proteins 0.000 claims 3
- 210000004027 cells Anatomy 0.000 claims 2
- 239000011435 rock Substances 0.000 claims 2
- 238000010241 blood sampling Methods 0.000 claims 1
- 230000000403 immunocorrecting Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Claims (1)
где Е-РОКн - показатель нормы, определяемый для каждой лаборатории в регионе;
Е-РОКб - показатель Е-РОК больного,
где Е-РОКб - показатель Е-РОК больного без Т-активина;
Е-РОКт - показатель Е-РОК больного при нагрузке Т-активином, и при значении ПОТ, равном или более 0,8, ПРТ, равном или более 1,0, диагностируют нормальное состояние организма;
при ПОТ более 0,8, ПРТ менее 1,0, диагностируют компенсированный гипореактивный 1 тип иммунодефицитного состояния (ИДС),
при ПОТ меньше 0,8, ПРТ равном или более 1,0 судят о наличии компенсированного 2 типа ИДС,
при ПОТ менее 0,8, ПРТ менее 1,0 диагностируют декомпенсированный 3 тип ИДС и определяют показания к иммунокоррегирующей терапии.A method for diagnosing an immunodeficiency state, including blood sampling, isolation of mononuclear cells, conducting a rosette reaction and evaluating the quantitative content of T cells, characterized in that they further determine the immunoreactivity of the cells in an in vitro rosette load test with T-activin concentration of 1.5 · 10 -4 μg / ml and determine the indicator of the relative content of T cells (POT) and the indicator of reactivity of T cells (PRT) according to the formulas:
where E-ROKn is the norm indicator determined for each laboratory in the region;
E-ROKb - an indicator of the patient's E-ROK,
where E-ROKb is an indicator of the patient's E-ROK without T-activin;
E-ROCK - the indicator of the patient's E-ROCK when loaded with T-activin, and when the value of POT equal to or more than 0.8, PRT equal to or more than 1.0, diagnose the normal state of the body;
with POT more than 0.8, PRT less than 1.0, diagnosed with compensated hyporeactive type 1 immunodeficiency state (IDS),
when POT less than 0.8, PRT equal to or more than 1.0 judge the presence of compensated type 2 IDS,
with POT less than 0.8, PRT less than 1.0, a decompensated type 3 of IDS is diagnosed and indications for immunocorrective therapy are determined.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU99120946/14A RU2179316C2 (en) | 1999-10-01 | 1999-10-01 | Method of diagnosis of immunodeficiency state |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU99120946/14A RU2179316C2 (en) | 1999-10-01 | 1999-10-01 | Method of diagnosis of immunodeficiency state |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU99120946A true RU99120946A (en) | 2001-08-10 |
| RU2179316C2 RU2179316C2 (en) | 2002-02-10 |
Family
ID=20225500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU99120946/14A RU2179316C2 (en) | 1999-10-01 | 1999-10-01 | Method of diagnosis of immunodeficiency state |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2179316C2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2564938C1 (en) * | 2014-07-31 | 2015-10-10 | Федеральное государственное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Method for prevention of variable immunodeficiency with predominant immunoregulatory t-cell disorder in children aged 3 years and more taking drinking water with hyperchlorination product residues |
| RU2568853C1 (en) * | 2014-09-30 | 2015-11-20 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Method for preventing variable immunodeficiency with predominant variance of b-cell count and functional activity in children of three years and more using drinking water with residual amount of hyperchlorination products |
| RU2574003C1 (en) * | 2014-10-24 | 2016-01-27 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Method for prevention of variable immunodeficiency primarily involving monocytes and macrophages of immune system in children aged 3 years and older, consuming drinking water with residual amounts of hyperchlorination products |
| RU2734029C1 (en) * | 2020-01-10 | 2020-10-12 | федеральное государственное бюджетное образовательное учреждение высшего образования "Северный государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for determining immunodeficiency states based on determining intracellular vitamins |
-
1999
- 1999-10-01 RU RU99120946/14A patent/RU2179316C2/en not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wu et al. | Analysis of the Albumin cobalt Binding (ACB TM) test as an adjunct to cardiac troponin I for the early detection of acute myocardial infarction | |
| Phelps et al. | Prevalence of genetic haemochromatosis among diabetic patients | |
| Roche et al. | Study of urinary and fecal excretion of radioactive chromium Cr 51 in man. Its use in the measurement of intestinal blood loss associated with hookworm infection | |
| Duane et al. | Intestinal iron absorption in chronic alcoholics | |
| Hägg et al. | Value of basal plasma cortisol assays in the assessment of pituitary‐adrenal insufficiency | |
| Cacciari et al. | Short stature and celiac disease: a relationship to consider even in patients with no gastrointestinal tract symptoms | |
| Hodgkin et al. | Vitamin-D deficiency in Asians at home and in Britain | |
| Gopal et al. | Abnormal findings on liver function tests: Interpreting results to narrow the diagnosis and establish a prognosis | |
| Whiting et al. | Serum and urine N-acetyl-β-D-glucosaminidase in diabetics on diagnosis and subsequent treatment, and stable insulin dependent diabetics | |
| Roberts et al. | Serum fructosamine: a screening test for diabetes in pregnancy | |
| Sheehan et al. | Predictive values of various liver function tests with respect to the diagnosis of liver disease | |
| Wood et al. | The orotic aciduria of pregnancy | |
| Forbes et al. | Techniques for estimating body composition | |
| RU99120946A (en) | METHOD FOR DIAGNOSTIC OF IMMUNO DEFICIENCY STATE | |
| Woloszczuk et al. | Neopterin and interferon gamma serum levels in patients with heart and kidney transplants | |
| Zuckier et al. | Schiling evaluation of permicious anemia: current status | |
| Aisen et al. | A rapid screening test for deficiency of plasma ceruloplasmin and its value in the diagnosis of Wilson's disease | |
| Chen et al. | Radioimmunoassay of parathyroid hormone: peripheral plasma immunoreactive parathyroid hormone response to ethylenediaminetetraacetate | |
| Jelen et al. | The possible relation between late pregnancy hypertension and 5‐hydroxytryptamine levels in maternal blood | |
| Carlson et al. | D-Xylose hydrogen breath tests compared to absorption kinetics in human patients with and without malabsorption | |
| Arola et al. | Strip test is reliable in common prevalences of hypolactasia | |
| Walsh et al. | Significance of non-steady-state serum digoxin concentrations | |
| WATANABE et al. | Primary Aldosteronism with Ipsilateral Adrenal Cyst Report of a Case | |
| Kind et al. | The effect of C3H mouse mammary tumour on the levels of serum and urine analytes in vivo | |
| Lucas et al. | Jejunal surface pH measurements in tropical sprue |