RU97120998A - FUMARATE (R) - (METHYLAMINOSULFONYLMETHYL) -3- (N-METHYLPYRROLIDIN-2-YLMETHYL) -1H-INDOLA, METHOD FOR ITS PREPARATION, MEANS FOR TREATING MIGRAINE, PHARMACEUTICAL LENGIS - Google Patents
FUMARATE (R) - (METHYLAMINOSULFONYLMETHYL) -3- (N-METHYLPYRROLIDIN-2-YLMETHYL) -1H-INDOLA, METHOD FOR ITS PREPARATION, MEANS FOR TREATING MIGRAINE, PHARMACEUTICAL LENGISInfo
- Publication number
- RU97120998A RU97120998A RU97120998/04A RU97120998A RU97120998A RU 97120998 A RU97120998 A RU 97120998A RU 97120998/04 A RU97120998/04 A RU 97120998/04A RU 97120998 A RU97120998 A RU 97120998A RU 97120998 A RU97120998 A RU 97120998A
- Authority
- RU
- Russia
- Prior art keywords
- fumarate
- methylaminosulfonylmethyl
- ylmethyl
- methylpyrrolidin
- treating migraine
- Prior art date
Links
- VZCYOOQTPOCHFL-UHFFFAOYSA-N fumaric acid Chemical compound OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title claims 5
- 206010027599 Migraine Diseases 0.000 title claims 4
- 208000008085 Migraine Disorders Diseases 0.000 title claims 4
- -1 METHYLAMINOSULFONYLMETHYL Chemical class 0.000 title 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N (E)-but-2-enedioate;hydron Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 4
- BWQZTHPHLITOOZ-CQSZACIVSA-N N-methyl-1-[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indol-5-yl]methanesulfonamide Chemical compound C12=CC(CS(=O)(=O)NC)=CC=C2NC=C1C[C@H]1CCCN1C BWQZTHPHLITOOZ-CQSZACIVSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000001530 fumaric acid Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- TZQSNURHFSOKAI-WZGZYPNHSA-N (E)-but-2-enedioic acid;N-methyl-1-[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indol-5-yl]methanesulfonamide Chemical compound OC(=O)\C=C\C(O)=O.C12=CC(CS(=O)(=O)NC)=CC=C2NC=C1C[C@H]1CCCN1C TZQSNURHFSOKAI-WZGZYPNHSA-N 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
Claims (6)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9510223.2A GB9510223D0 (en) | 1995-05-20 | 1995-05-20 | Therapeutic agent |
GB9510223.2 | 1995-05-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU97120998A true RU97120998A (en) | 1999-08-27 |
RU2161618C2 RU2161618C2 (en) | 2001-01-10 |
Family
ID=10774766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU97120998/04A RU2161618C2 (en) | 1995-05-20 | 1996-04-10 | (r)-(methylaminosulfonylmethyl)-3-(n-methylpyrrolidine-2-yl- -methyl)-1h-indole fumarate, method of its preparing, agent for treatment of mirgaine, pharmaceutical composition for migraine treatment |
Country Status (42)
Country | Link |
---|---|
US (1) | US5994387A (en) |
EP (1) | EP0827503B1 (en) |
JP (1) | JP3233940B2 (en) |
KR (1) | KR100295255B1 (en) |
CN (1) | CN1063175C (en) |
AP (1) | AP738A (en) |
AR (1) | AR003949A1 (en) |
AT (1) | ATE194986T1 (en) |
AU (1) | AU701154B2 (en) |
BG (1) | BG63046B1 (en) |
BR (1) | BR9610858A (en) |
CA (1) | CA2219631C (en) |
CO (1) | CO5040221A1 (en) |
CZ (1) | CZ287939B6 (en) |
DE (1) | DE69609504T2 (en) |
DK (1) | DK0827503T3 (en) |
DZ (1) | DZ2034A1 (en) |
ES (1) | ES2148753T3 (en) |
GB (1) | GB9510223D0 (en) |
GR (1) | GR3034290T3 (en) |
HK (1) | HK1017884A1 (en) |
HR (1) | HRP960223B1 (en) |
HU (1) | HU217657B (en) |
IL (1) | IL118239A (en) |
IS (1) | IS1908B (en) |
LV (1) | LV11992B (en) |
MA (1) | MA23876A1 (en) |
MX (1) | MX9708966A (en) |
MY (1) | MY132066A (en) |
NO (1) | NO312068B1 (en) |
NZ (1) | NZ306448A (en) |
OA (1) | OA10747A (en) |
PL (1) | PL183142B1 (en) |
PT (1) | PT827503E (en) |
RU (1) | RU2161618C2 (en) |
SK (1) | SK281782B6 (en) |
TN (1) | TNSN96074A1 (en) |
TR (1) | TR199701397T1 (en) |
UA (1) | UA44320C2 (en) |
WO (1) | WO1996036632A1 (en) |
YU (1) | YU29496A (en) |
ZA (1) | ZA963938B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9825988D0 (en) * | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
US20100266638A1 (en) * | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
WO2014012859A1 (en) * | 2012-07-19 | 2014-01-23 | Boehringer Ingelheim International Gmbh | Fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy- chinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-one, its use as medicament and the preparation thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3906406C1 (en) * | 1989-03-01 | 1990-10-25 | Goedecke Ag, 1000 Berlin, De | |
EP0592438B1 (en) * | 1990-10-15 | 1997-08-27 | Pfizer Inc. | Indole derivatives |
US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
AP486A (en) * | 1993-04-27 | 1996-04-16 | Pfizer | Indole derivatives. |
-
1995
- 1995-05-20 GB GBGB9510223.2A patent/GB9510223D0/en active Pending
-
1996
- 1996-04-10 TR TR97/01397T patent/TR199701397T1/en unknown
- 1996-04-10 DK DK96912013T patent/DK0827503T3/en active
- 1996-04-10 UA UA97126158A patent/UA44320C2/en unknown
- 1996-04-10 AU AU55005/96A patent/AU701154B2/en not_active Ceased
- 1996-04-10 BR BR9610858A patent/BR9610858A/en not_active Application Discontinuation
- 1996-04-10 NZ NZ306448A patent/NZ306448A/en unknown
- 1996-04-10 WO PCT/EP1996/001560 patent/WO1996036632A1/en active IP Right Grant
- 1996-04-10 PL PL96323143A patent/PL183142B1/en unknown
- 1996-04-10 RU RU97120998/04A patent/RU2161618C2/en not_active IP Right Cessation
- 1996-04-10 MX MX9708966A patent/MX9708966A/en not_active IP Right Cessation
- 1996-04-10 HU HU9801761A patent/HU217657B/en not_active IP Right Cessation
- 1996-04-10 CZ CZ19973648A patent/CZ287939B6/en not_active IP Right Cessation
- 1996-04-10 JP JP53448896A patent/JP3233940B2/en not_active Expired - Fee Related
- 1996-04-10 CN CN96194043A patent/CN1063175C/en not_active Expired - Fee Related
- 1996-04-10 EP EP96912013A patent/EP0827503B1/en not_active Expired - Lifetime
- 1996-04-10 AT AT96912013T patent/ATE194986T1/en not_active IP Right Cessation
- 1996-04-10 KR KR1019970708280A patent/KR100295255B1/en not_active IP Right Cessation
- 1996-04-10 SK SK1541-97A patent/SK281782B6/en unknown
- 1996-04-10 US US08/952,792 patent/US5994387A/en not_active Expired - Fee Related
- 1996-04-10 PT PT96912013T patent/PT827503E/en unknown
- 1996-04-10 DE DE69609504T patent/DE69609504T2/en not_active Expired - Fee Related
- 1996-04-10 ES ES96912013T patent/ES2148753T3/en not_active Expired - Lifetime
- 1996-04-10 CA CA002219631A patent/CA2219631C/en not_active Expired - Fee Related
- 1996-04-11 AP APAP/P/1996/000801A patent/AP738A/en active
- 1996-05-10 AR ARP960102519A patent/AR003949A1/en unknown
- 1996-05-13 IL IL11823996A patent/IL118239A/en not_active IP Right Cessation
- 1996-05-16 HR HR960223A patent/HRP960223B1/en not_active IP Right Cessation
- 1996-05-16 YU YU29496A patent/YU29496A/en unknown
- 1996-05-17 CO CO96025158A patent/CO5040221A1/en unknown
- 1996-05-17 MY MYPI96001888A patent/MY132066A/en unknown
- 1996-05-17 ZA ZA9603938A patent/ZA963938B/en unknown
- 1996-05-17 TN TNTNSN96074A patent/TNSN96074A1/en unknown
- 1996-05-17 MA MA24243A patent/MA23876A1/en unknown
- 1996-05-18 DZ DZ960077A patent/DZ2034A1/en active
-
1997
- 1997-10-30 IS IS4605A patent/IS1908B/en unknown
- 1997-11-13 NO NO19975210A patent/NO312068B1/en not_active IP Right Cessation
- 1997-11-18 BG BG102053A patent/BG63046B1/en unknown
- 1997-11-20 OA OA70132A patent/OA10747A/en unknown
- 1997-12-11 LV LVP-97-256A patent/LV11992B/en unknown
-
1998
- 1998-10-20 HK HK98111337A patent/HK1017884A1/en not_active IP Right Cessation
-
2000
- 2000-08-30 GR GR20000401977T patent/GR3034290T3/en not_active IP Right Cessation
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