RU97105593A - VACCINE FOR PREVENTION OF ABDOMINAL TYPE - Google Patents
VACCINE FOR PREVENTION OF ABDOMINAL TYPEInfo
- Publication number
- RU97105593A RU97105593A RU97105593/14A RU97105593A RU97105593A RU 97105593 A RU97105593 A RU 97105593A RU 97105593/14 A RU97105593/14 A RU 97105593/14A RU 97105593 A RU97105593 A RU 97105593A RU 97105593 A RU97105593 A RU 97105593A
- Authority
- RU
- Russia
- Prior art keywords
- sodium
- prevention
- antigen
- vaccine
- phenol
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title claims 2
- 229960005486 vaccines Drugs 0.000 title claims 2
- 230000003187 abdominal Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 claims 3
- 102000038129 antigens Human genes 0.000 claims 3
- 108091007172 antigens Proteins 0.000 claims 3
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims 3
- 229910052708 sodium Inorganic materials 0.000 claims 3
- 239000011734 sodium Substances 0.000 claims 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 108010059712 Pronase Proteins 0.000 claims 1
- 102000006382 Ribonucleases Human genes 0.000 claims 1
- 108010083644 Ribonucleases Proteins 0.000 claims 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 201000008297 typhoid fever Diseases 0.000 claims 1
Claims (1)
Ви-антиген - 0,004-0,006
Гидроортофосфат натрия - 0,01-0,02
Дигидроортофосфат натрия - 1,75-1,85
Хлорид натрия - 0,84-0,90
Фенол - 0,10-0,15
Вода дистиллированная - До 100A vaccine preparation for the prevention of typhoid fever based on a physiological solution of capsular Vi antigen isolated from Salmonella typhi containing excipients, characterized in that the preparation contains antigen additionally treated with deoxy and ribonuclease, then pronase and purified gel by filtration, and as auxiliary substances contains hydrofluorophosphate and sodium dihydroorthophosphate and phenol in the following ratio of components, wt.%:
Vi antigen - 0.004-0.006
Sodium hydroorthophosphate - 0.01-0.02
Sodium dihydroorthophosphate - 1.75-1.85
Sodium Chloride - 0.84-0.90
Phenol - 0.10-0.15
Distilled water - Up to 100
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU97105593A RU2111012C1 (en) | 1997-04-15 | 1997-04-15 | Vaccine preparation for typhoid fever prophylaxis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU97105593A RU2111012C1 (en) | 1997-04-15 | 1997-04-15 | Vaccine preparation for typhoid fever prophylaxis |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2111012C1 RU2111012C1 (en) | 1998-05-20 |
RU97105593A true RU97105593A (en) | 1999-01-27 |
Family
ID=20191731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU97105593A RU2111012C1 (en) | 1997-04-15 | 1997-04-15 | Vaccine preparation for typhoid fever prophylaxis |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2111012C1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE240118T1 (en) * | 1998-08-28 | 2003-05-15 | Glaxosmithkline Biolog Sa | SALMONELLA TYPHI VACCINE COMPOSITIONS |
WO2012154072A1 (en) * | 2011-05-06 | 2012-11-15 | Aparin Petr Gennadievich | Exopolysaccharide of shigella sonnei bacteria, method for producing same, vaccine and pharmaceutical composition containing same |
-
1997
- 1997-04-15 RU RU97105593A patent/RU2111012C1/en active
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