RU97105384A - APPLICATION OF 5-HT1F AGONISTS FOR INHIBITION OF 5HT1F- MEDIATED NEUROGENIC MINGIAL TRANSUSIONS - Google Patents

APPLICATION OF 5-HT1F AGONISTS FOR INHIBITION OF 5HT1F- MEDIATED NEUROGENIC MINGIAL TRANSUSIONS

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Publication number
RU97105384A
RU97105384A RU97105384/14A RU97105384A RU97105384A RU 97105384 A RU97105384 A RU 97105384A RU 97105384/14 A RU97105384/14 A RU 97105384/14A RU 97105384 A RU97105384 A RU 97105384A RU 97105384 A RU97105384 A RU 97105384A
Authority
RU
Russia
Prior art keywords
agonist
transusions
mingial
5ht1f
inhibition
Prior art date
Application number
RU97105384/14A
Other languages
Russian (ru)
Other versions
RU2183457C2 (en
Inventor
Эдмунд Аудиа Джеймс
Энн Бранчек Тереза
Лоис Кохен Марлен
Вилис Джонсон Кирк
Алан Фебас Ли
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/318,330 external-priority patent/US5698571A/en
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of RU97105384A publication Critical patent/RU97105384A/en
Application granted granted Critical
Publication of RU2183457C2 publication Critical patent/RU2183457C2/en

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Claims (7)

1. Применение 5-HT1F агониста, который проявляет минимальные сосудосуживающие свойства, для производства лекарственного средства для предупреждения или лечения мигреневой боли.1. The use of a 5-HT 1F agonist, which exhibits minimal vasoconstrictive properties, for the manufacture of a medicament for the prevention or treatment of migraine pain. 2. Применение 5-HT1F агониста, который проявляет минимальные сосудосуживающие свойства, для производства лекарственного средства для ингибирования нейрогенной менингиальной транссудации.2. The use of a 5-HT 1F agonist, which exhibits minimal vasoconstrictive properties, for the manufacture of a medicament for inhibiting neurogenic meningeal extravasation. 3. Применение 5-HT1F агониста по любому из п.п. 1 или 2, где указанный 5-HT1F агонист обладает Индексом Специфичности в интервале 5-10000.3. The use of a 5-HT 1F agonist according to any one of paragraphs. 1 or 2, wherein said 5-HT 1F agonist has a Specificity Index in the range of 5-10000. 4. Применение 5-HT1F по любому из п.п. 1 или 2, где указанный 5-HT1F агонист обладает Индексом Специфичности по меньшей мере 10.4. The use of 5-HT 1F according to any one of paragraphs. 1 or 2, wherein said 5-HT 1F agonist has a Specificity Index of at least 10. 5. Применение 5-HT1F по любому из п.п. 1 или 2, где указанный 5-HT1F агонист обладает Индексом Специфичности по меньшей мере 100.5. The use of 5-HT 1F according to any one of paragraphs. 1 or 2, wherein said 5-HT 1F agonist has a Specificity Index of at least 100. 6. Применение 5-HT1F по любому из п.п. 1 или 2, где указанный 5-HT1F агонист обладает Индексом Специфичности по меньшей мере 1000.6. The use of 5-HT 1F according to any one of paragraphs. 1 or 2, wherein said 5-HT 1F agonist has a Specificity Index of at least 1000. 7. Применение 5-HT1F агониста по любому из п.п. 1 или 2, где указанный 5-HT1F агонист обладает Индексом Специфичности по меньшей мере 10000.7. The use of a 5-HT 1F agonist according to any one of paragraphs. 1 or 2, wherein said 5-HT 1F agonist has a Specificity Index of at least 10,000.
RU97105384/14A 1994-10-05 1995-10-03 Method for applying 5_ht5-ht1f-antagonist for inhibiting 5_ht5-ht1f-mediated neurogenic meningeal transudation RU2183457C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/318,330 US5698571A (en) 1994-10-05 1994-10-05 5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine
US08/318,330 1994-10-05

Publications (2)

Publication Number Publication Date
RU97105384A true RU97105384A (en) 1999-05-20
RU2183457C2 RU2183457C2 (en) 2002-06-20

Family

ID=23237717

Family Applications (1)

Application Number Title Priority Date Filing Date
RU97105384/14A RU2183457C2 (en) 1994-10-05 1995-10-03 Method for applying 5_ht5-ht1f-antagonist for inhibiting 5_ht5-ht1f-mediated neurogenic meningeal transudation

Country Status (14)

Country Link
US (1) US5698571A (en)
EP (1) EP0705600A1 (en)
JP (1) JPH08208516A (en)
AU (1) AU688168B2 (en)
CA (1) CA2159767A1 (en)
CZ (1) CZ93097A3 (en)
HU (1) HUT77885A (en)
NO (1) NO971487D0 (en)
NZ (1) NZ296252A (en)
RU (1) RU2183457C2 (en)
TW (1) TW492864B (en)
UA (1) UA44284C2 (en)
WO (1) WO1996011006A1 (en)
ZA (1) ZA958314B (en)

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AU4074897A (en) * 1996-09-18 1998-04-14 Eli Lilly And Company A method for the prevention of migraine
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US8329734B2 (en) 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
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WO2005123043A2 (en) * 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
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BR112017018944A2 (en) 2015-03-02 2018-05-15 Afgin Pharma Llc method of treating a disease state or condition in humans with a carbinoid drug, and method of treating a disease state or condition in a mammal other than a human with carbinoid drug (s)
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
TWI826514B (en) * 2018-09-04 2023-12-21 美商美國禮來大藥廠 Chronic nightly dosing of lasmiditan for migraine prevention
AR119319A1 (en) 2019-07-09 2021-12-09 Lilly Co Eli PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-IL]-BENZAMIDE HEMISUCCINATE AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-IL]-BENZAMIDE

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