RU96107054A - METHOD FOR PHOTODYNAMIC THERAPY OF MALIGNANT NON-FORMATIONS - Google Patents

METHOD FOR PHOTODYNAMIC THERAPY OF MALIGNANT NON-FORMATIONS

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Publication number
RU96107054A
RU96107054A RU96107054/14A RU96107054A RU96107054A RU 96107054 A RU96107054 A RU 96107054A RU 96107054/14 A RU96107054/14 A RU 96107054/14A RU 96107054 A RU96107054 A RU 96107054A RU 96107054 A RU96107054 A RU 96107054A
Authority
RU
Russia
Prior art keywords
photosensitizer
photodynamic therapy
zone
introduction
formations
Prior art date
Application number
RU96107054/14A
Other languages
Russian (ru)
Other versions
RU2146159C1 (en
Inventor
В.Б. Лощенов
Г.А. Меерович
А.А. Стратонников
С.С. Харнас
Р.В. Штайнер
Original Assignee
Акционерное общество закрытого типа "Биоспек"
Filing date
Publication date
Application filed by Акционерное общество закрытого типа "Биоспек" filed Critical Акционерное общество закрытого типа "Биоспек"
Priority to RU96107054A priority Critical patent/RU2146159C1/en
Priority claimed from RU96107054A external-priority patent/RU2146159C1/en
Publication of RU96107054A publication Critical patent/RU96107054A/en
Application granted granted Critical
Publication of RU2146159C1 publication Critical patent/RU2146159C1/en

Links

Claims (1)

1. Способ фотодинамической терапии злокачественных опухолей, включающий введение в организм пациента фотосенсибилизатора и облучение зоны опухолевого роста по достижению терапевтической концентрации фотосенсибилизатора в этой зоне терапевтическим оптическим излучением, поглощаемым фотосенсибилизатором, плотностью мощности 100-800 мВт/см2 и световой дозой 100-500 Дж/см2, отличающийся тем, что непосредственно перед введением фотосенсибилизатора облучают зону опухолевого роста низкоинтенсивным лазерным излучением с плотностью мощности 5-200 мВт/см2 и световой дозой 2-20 Дж/см2, во время или непосредственно после введения фотосенсибилизатора облучают упомянутую зону оптическим излучением, поглощаемым упомянутым фотосенсибилизатором, с плотностью мощности 20-800 мВт/см2 и световой дозой 20-60 Дж/см2,
2. Способ фотодинамической терапии по п. 1, отличающийся тем, что облучение зоны опухолевого роста низкоинтенсивным лазерным излучением осуществляют в спектральном диапазоне 0,8-0,9 мкм.1. The method of photodynamic therapy of malignant tumors, including the introduction of a photosensitizer into the patient’s body and irradiation of the tumor growth zone to achieve a therapeutic concentration of the photosensitizer in this zone with therapeutic optical radiation absorbed by the photosensitizer, a power density of 100-800 mW / cm 2 and a light dose of 100-500 J / cm 2 , characterized in that immediately before the introduction of the photosensitizer, the tumor growth zone is irradiated with low-intensity laser radiation with a power density of 5- 200 mW / cm 2 and a light dose of 2-20 J / cm 2 , during or immediately after the introduction of the photosensitizer, the said zone is irradiated with optical radiation absorbed by the photosensitizer, with a power density of 20-800 mW / cm 2 and a light dose of 20-60 J / cm 2
2. The method of photodynamic therapy according to claim 1, characterized in that the irradiation of the tumor growth zone with low-intensity laser radiation is carried out in the spectral range of 0.8-0.9 microns.
RU96107054A 1996-04-11 1996-04-11 Method for applying photodynamic therapy of malignant neoplasms RU2146159C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU96107054A RU2146159C1 (en) 1996-04-11 1996-04-11 Method for applying photodynamic therapy of malignant neoplasms

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU96107054A RU2146159C1 (en) 1996-04-11 1996-04-11 Method for applying photodynamic therapy of malignant neoplasms

Publications (2)

Publication Number Publication Date
RU96107054A true RU96107054A (en) 1998-07-27
RU2146159C1 RU2146159C1 (en) 2000-03-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU96107054A RU2146159C1 (en) 1996-04-11 1996-04-11 Method for applying photodynamic therapy of malignant neoplasms

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RU (1) RU2146159C1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2196623C2 (en) * 2000-07-21 2003-01-20 Соколов Виктор Викторович Method for treating malignant tumors
RU2187347C1 (en) * 2001-01-12 2002-08-20 Государственный научный центр Российской Федерации "НИОПИК" Method and applicator for photodynamic therapy
RU2704202C1 (en) * 2019-07-03 2019-10-24 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) Method of photodynamic therapy of growth surface solid connective-tissue sarcoma of m-1 rats
RU2724867C2 (en) * 2020-02-25 2020-06-25 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) Method of photodynamic therapy of transplanted ectodermal tumor of melanoma b16 of mice

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