RU96105946A - METHOD FOR SENSITIZING CANCER CELLS TO A LYSIS MEDIATED BY KILLER CELLS - Google Patents
METHOD FOR SENSITIZING CANCER CELLS TO A LYSIS MEDIATED BY KILLER CELLSInfo
- Publication number
- RU96105946A RU96105946A RU96105946/14A RU96105946A RU96105946A RU 96105946 A RU96105946 A RU 96105946A RU 96105946/14 A RU96105946/14 A RU 96105946/14A RU 96105946 A RU96105946 A RU 96105946A RU 96105946 A RU96105946 A RU 96105946A
- Authority
- RU
- Russia
- Prior art keywords
- antiestrogen
- killer cells
- triphenylethylene
- cells
- killer
- Prior art date
Links
- 201000011510 cancer Diseases 0.000 title claims 5
- 230000009089 cytolysis Effects 0.000 title claims 5
- 230000002934 lysing Effects 0.000 title claims 5
- 230000001404 mediated Effects 0.000 title claims 5
- 230000001235 sensitizing Effects 0.000 title claims 4
- 231100000202 sensitizing Toxicity 0.000 title claims 4
- 230000002147 killing Effects 0.000 claims 9
- 230000001833 anti-estrogenic Effects 0.000 claims 8
- 239000000328 estrogen antagonist Substances 0.000 claims 8
- MKYQPGPNVYRMHI-UHFFFAOYSA-N Triphenylethylene Chemical group C=1C=CC=CC=1C=C(C=1C=CC=CC=1)C1=CC=CC=C1 MKYQPGPNVYRMHI-UHFFFAOYSA-N 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 4
- 239000011780 sodium chloride Substances 0.000 claims 4
- 229960001603 Tamoxifen Drugs 0.000 claims 3
- NKANXQFJJICGDU-QPLCGJKRSA-N Tamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 NKANXQFJJICGDU-QPLCGJKRSA-N 0.000 claims 3
- XFCLJVABOIYOMF-QPLCGJKRSA-N Toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 claims 3
- 229960005026 toremifene Drugs 0.000 claims 3
- 102000000588 Interleukin-2 Human genes 0.000 claims 2
- 108010002350 Interleukin-2 Proteins 0.000 claims 2
- 230000003308 immunostimulating Effects 0.000 claims 2
- 229940046836 Anti-estrogens Drugs 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000005755 formation reaction Methods 0.000 claims 1
- 239000003022 immunostimulating agent Substances 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
Claims (11)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10351993A | 1993-08-09 | 1993-08-09 | |
US08/103,519 | 1993-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU96105946A true RU96105946A (en) | 1998-09-27 |
RU2153332C2 RU2153332C2 (en) | 2000-07-27 |
Family
ID=22295643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU96105946/14A RU2153332C2 (en) | 1993-08-09 | 1994-08-02 | Method of sensitization of cancer cells to lysis mediated by killer-cells |
Country Status (16)
Country | Link |
---|---|
US (1) | US5788964A (en) |
EP (1) | EP0726772B1 (en) |
JP (1) | JPH09501174A (en) |
KR (1) | KR100340091B1 (en) |
AT (1) | ATE208207T1 (en) |
AU (1) | AU693459B2 (en) |
CA (1) | CA2168584C (en) |
CZ (1) | CZ285508B6 (en) |
DE (1) | DE69429011T2 (en) |
ES (1) | ES2167373T3 (en) |
HU (1) | HUT74425A (en) |
NO (1) | NO316823B1 (en) |
NZ (1) | NZ269149A (en) |
RU (1) | RU2153332C2 (en) |
SK (1) | SK283124B6 (en) |
WO (1) | WO1995004544A1 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2686899B1 (en) * | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | NOVEL BIOLOGICALLY ACTIVE POLYPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
HU223344B1 (en) * | 1997-08-13 | 2004-06-28 | Máté Hidvégi | Immunostimulant and metastasis-inhibiting fermented dried material, pharmaceutical compositions containing same, process for its production and its uses |
US6413533B1 (en) | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
US20030130316A1 (en) * | 2000-03-20 | 2003-07-10 | Steiner Mitchell S. | Method for chemoprevention of prostate cancer |
US20040092602A1 (en) * | 1998-05-07 | 2004-05-13 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
US20040176470A1 (en) * | 1998-05-07 | 2004-09-09 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
US6632447B1 (en) | 1998-05-07 | 2003-10-14 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
ATE283043T1 (en) | 1998-05-07 | 2004-12-15 | Univ Tennessee Res Corp | MEDICATION FOR THE TREATMENT OF INTRAEPITHELIAL PROSTATE NEOPLASIA |
US6410043B1 (en) | 1998-05-07 | 2002-06-25 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
EP1372717A2 (en) * | 2001-03-23 | 2004-01-02 | Aphton Corporation | Combination treatment of pancreatic cancer |
US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
EP1401477A4 (en) * | 2001-05-25 | 2005-02-02 | Human Genome Sciences | Chemokine beta-1 fusion proteins |
CA2450898A1 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
US6555095B1 (en) | 2001-12-14 | 2003-04-29 | Avon Products, Inc. | Topical compositions and methods of application |
ES2500918T3 (en) | 2001-12-21 | 2014-10-01 | Human Genome Sciences, Inc. | Albumin and interferon beta fusion proteins |
WO2004088326A2 (en) * | 2003-03-28 | 2004-10-14 | Aphton Corporation | Gastrin hormone immunoassays |
ES2426916T3 (en) * | 2003-08-01 | 2013-10-25 | A & G Pharmaceutical, Inc. | Compositions and procedures to restore sensitivity to treatment with HER2 antagonists |
EP1730193A2 (en) * | 2004-03-29 | 2006-12-13 | Receptor Biologix, Inc. | Monoclonal antibodies to gastrin hormone |
CN101048659B (en) * | 2004-09-22 | 2013-03-13 | 受体生物技术公司 | Monoclonal antibodies to progastrin |
US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
AU2011211699B2 (en) * | 2010-02-04 | 2015-01-22 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
KR20120093002A (en) * | 2011-02-14 | 2012-08-22 | (주)에이티젠 | Method for diagnosing cancer and diagnosis kit using measurement of nk cell activity |
WO2016106146A1 (en) | 2014-12-23 | 2016-06-30 | The Regents Of The University Of California | Methods for immunomodulation of cancer and infectious disease therapy |
KR20200015943A (en) | 2017-06-15 | 2020-02-13 | 캔설 어드밴스 아이엔씨 | Compositions and Methods for Inducing Humoral and Cellular Immunity to Tumors and Cancers |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5024833A (en) * | 1988-03-10 | 1991-06-18 | Industrial Farmaceutica Serono Spa | Combined interferon/antiestrogen therapy for treatment of breast cancer |
US5057423A (en) * | 1987-12-18 | 1991-10-15 | University Of Pittsburgh | Method for the preparation of pure LAK-active lymphocytes |
US5189212A (en) * | 1990-09-07 | 1993-02-23 | University Of Georgia Research Foundation, Inc. | Triarylethylene carboxylic acids with estrogenic activity |
CA2109426A1 (en) * | 1991-04-30 | 1992-10-31 | Hiroyuki Kouji | Triphenylethylene derivative and pharmaceutical drug containing the same |
-
1994
- 1994-08-02 AT AT94922877T patent/ATE208207T1/en not_active IP Right Cessation
- 1994-08-02 KR KR1019960700689A patent/KR100340091B1/en not_active IP Right Cessation
- 1994-08-02 CZ CZ96316A patent/CZ285508B6/en not_active IP Right Cessation
- 1994-08-02 JP JP7506232A patent/JPH09501174A/en active Pending
- 1994-08-02 NZ NZ269149A patent/NZ269149A/en unknown
- 1994-08-02 EP EP94922877A patent/EP0726772B1/en not_active Expired - Lifetime
- 1994-08-02 RU RU96105946/14A patent/RU2153332C2/en not_active IP Right Cessation
- 1994-08-02 AU AU72637/94A patent/AU693459B2/en not_active Ceased
- 1994-08-02 US US08/596,121 patent/US5788964A/en not_active Expired - Lifetime
- 1994-08-02 HU HU9600294A patent/HUT74425A/en unknown
- 1994-08-02 WO PCT/FI1994/000333 patent/WO1995004544A1/en active IP Right Grant
- 1994-08-02 CA CA002168584A patent/CA2168584C/en not_active Expired - Lifetime
- 1994-08-02 ES ES94922877T patent/ES2167373T3/en not_active Expired - Lifetime
- 1994-08-02 DE DE69429011T patent/DE69429011T2/en not_active Expired - Fee Related
- 1994-08-02 SK SK180-96A patent/SK283124B6/en unknown
-
1996
- 1996-02-08 NO NO19960511A patent/NO316823B1/en unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU96105946A (en) | METHOD FOR SENSITIZING CANCER CELLS TO A LYSIS MEDIATED BY KILLER CELLS | |
JP2848556B2 (en) | Cough / cold combination drug containing non-steroidal anti-inflammatory drug | |
JPH06509099A (en) | Compositions and methods for transdermal delivery of diclofenac | |
ES2830447T3 (en) | Method for the prevention and / or treatment of cognitive impairment associated with aging and neuroinflammation | |
RU96122884A (en) | HUMAN CANCER TREATMENT METHOD | |
KR960703616A (en) | Sensitization of Cancer Cells for Killer Cell Intercalation | |
RU2007138582A (en) | ORAL DOSAGE FORMS OF HEMCITABINE DERIVATIVES | |
PT2033635E (en) | Use of phenylbutyric acid or salts thereof for treating pruritus | |
RU95101385A (en) | Products containing g-csf and tnf-binding protein | |
JP2011506505A (en) | Medicament and its production method and use in the treatment of painful neuropathy | |
ES2698363T3 (en) | Compositions of oxprenolol to treat cancer | |
KR900017577A (en) | How to raise cell-mediated immunity using polyamine derivatives | |
US9750714B2 (en) | Pharmaceutical use of 3, 4-bis-benzylsulfonylbutyronitrile | |
JP2008143856A (en) | Pharmaceutical compounded with nonsteroidal anti-inflammatory agent | |
JP2611003B2 (en) | Immunostimulants | |
JP2021506907A5 (en) | ||
US9149488B2 (en) | Pharmaceutical composition and use of diethyl (2-cyanoethyl)phosphonate | |
JPH08268884A (en) | Use of 7-substituted-2-aminotetralin for preparing medicinalcomposition being useful for therapy of septic shock and antipyretic and antiphlogistic medicinal composition | |
EA200300430A1 (en) | NEW PHARMACEUTICAL COMPOSITIONS CONTAINING EPINASTINES AND PSEVDOEDFEDRIN | |
BRPI0902144A2 (en) | process for preparing a solid oral administration pharmaceutical composition containing the active ingredients glycosamine and meloxicam and use of the association between glycosamine and meloxicam | |
RU2019180C1 (en) | Remedy for treatment of hypodermic fibrosarcoma and method of its preparation | |
CN1166320A (en) | Composite of zinc containing compound and glutamines | |
EP3110412B1 (en) | 4-benzylsulfonyl-2-butenenitrile | |
RU2021118773A (en) | COMPOUNDS SUITABLE FOR HIV THERAPY | |
JP2015189758A (en) | external pharmaceutical composition |