RU95114363A - Azaspiro-compound derivatives, method of their synthesis, pharmaceutical composition, agents for obesity treatment, agents for effective disorder treatment - Google Patents
Azaspiro-compound derivatives, method of their synthesis, pharmaceutical composition, agents for obesity treatment, agents for effective disorder treatmentInfo
- Publication number
- RU95114363A RU95114363A RU95114363/04A RU95114363A RU95114363A RU 95114363 A RU95114363 A RU 95114363A RU 95114363/04 A RU95114363/04 A RU 95114363/04A RU 95114363 A RU95114363 A RU 95114363A RU 95114363 A RU95114363 A RU 95114363A
- Authority
- RU
- Russia
- Prior art keywords
- group
- alkyl
- agents
- hydrogen
- rmeans
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
FIELD: organic chemistry. SUBSTANCE: product: compounds of the formula (I)and their pharmaceutically acceptable salts where: m = 1-3; n = 2-6; Rmeans phenyl containing possibly one or some substituents taken from halogen, hydroxy-group, alkoxy-group, alkanoyl, alkyl, halogenated alkyl, alkylthio-group, alkylsulfinyl, alkylsulfonyl, cyano-group, nitro-group, possibly substituted amino-group, possibly substituted sulfamoyl, possibly substituted carbamoyl or phenyl, or Rmeans naphthyl; Rmeans hydrogen, alkyl or phenyl; Rmeans hydrogen, alkyl, alkenyl or alkoxyalkyl; Rmeans hydrogen or hydroxy-group and Rmeans hydrogen, or Rand Rform together the bond. Synthesized compounds were used for obesity, EFFECTIVE disorders treatment. EFFECT: improved method of synthesis, enhanced effectiveness of treatment.
Claims (1)
и их фармацевтически пригодные соли, у которых m - число от 1 до 3; n - число от 2 до 6; R1 - фенил, возможно имеющий один или несколько заместителей, выбранных из галогена, гидроксигруппы, алкоксигруппы, алкиноила, алкила, галогенированного алкила, алкилтиогруппы, алкилсульфинила, алкилсульфонила, цианогруппы, нитрогруппы, возможно замещенной аминогруппы, возможно замещенного сульфонила, возможно замещенного карбамоила или фенила, или R1 - нафтил; R2 - водород, алкил или фенил; R3 - водород, алкил, алкенил или алкоксиалкил; R4 - водород или гидроксигруппа; R5 - водород или R5 и R4 вместе образуют связь, применяют для лечения ожирения и аффективных расстройств, например депрессивного состояния и состояния страха.Compounds of Formula I Suggested
and their pharmaceutically acceptable salts, in which m is a number from 1 to 3; n is a number from 2 to 6; R 1 is phenyl, possibly having one or more substituents selected from halogen, hydroxy, alkoxy, alkynoyl, alkyl, halogenated alkyl, alkylthio, alkylsulfinyl, alkylsulfonyl, cyano, nitro, optionally substituted amino, optionally substituted sulfonyl, optionally substituted carbamyl or R 1 is naphthyl; R 2 is hydrogen, alkyl or phenyl; R 3 is hydrogen, alkyl, alkenyl or alkoxyalkyl; R 4 is hydrogen or hydroxy; R 5 is hydrogen, or R 5 and R 4 together form a bond, used to treat obesity and affective disorders, such as depression and fear.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9223445.9 | 1992-11-09 | ||
| GB929223445A GB9223445D0 (en) | 1992-11-09 | 1992-11-09 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU95114363A true RU95114363A (en) | 1997-03-20 |
Family
ID=48434178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU95114363/04A RU95114363A (en) | 1992-11-09 | 1993-10-23 | Azaspiro-compound derivatives, method of their synthesis, pharmaceutical composition, agents for obesity treatment, agents for effective disorder treatment |
Country Status (2)
| Country | Link |
|---|---|
| RU (1) | RU95114363A (en) |
| TW (1) | TW267163B (en) |
-
1993
- 1993-10-23 RU RU95114363/04A patent/RU95114363A/en unknown
-
1994
- 1994-05-06 TW TW83104119A patent/TW267163B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW267163B (en) | 1996-01-01 |
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