RU95109450A - Methods for drug delivery to the respiratory system, the mode of delivery of the drug in one or both lungs of patients who are not inserted an endotracheal tube, METHOD aerosol delivery of drug in the lungs of patients: methods for drug delivery to a branched region of the respiratory system, the patient, the delivery catheter aerosol MEDICINES FOR LUNG PATIENTS (OPTIONS): CATHETER SYSTEM FOR DELIVERY OF AEROSOL OF MEDICINES IN LUNG PATIENTS, CATHETER SYSTEM A FOR DELIVERY aerosol therapy the patient's lungs, the suction catheter FOR A tracheal tube and method of making catheters for spraying liquids with gas - Google Patents

Methods for drug delivery to the respiratory system, the mode of delivery of the drug in one or both lungs of patients who are not inserted an endotracheal tube, METHOD aerosol delivery of drug in the lungs of patients: methods for drug delivery to a branched region of the respiratory system, the patient, the delivery catheter aerosol MEDICINES FOR LUNG PATIENTS (OPTIONS): CATHETER SYSTEM FOR DELIVERY OF AEROSOL OF MEDICINES IN LUNG PATIENTS, CATHETER SYSTEM A FOR DELIVERY aerosol therapy the patient's lungs, the suction catheter FOR A tracheal tube and method of making catheters for spraying liquids with gas

Info

Publication number
RU95109450A
RU95109450A RU95109450/14A RU95109450A RU95109450A RU 95109450 A RU95109450 A RU 95109450A RU 95109450/14 A RU95109450/14 A RU 95109450/14A RU 95109450 A RU95109450 A RU 95109450A RU 95109450 A RU95109450 A RU 95109450A
Authority
RU
Russia
Prior art keywords
catheter
drug
channel
distal
aerosol
Prior art date
Application number
RU95109450/14A
Other languages
Russian (ru)
Other versions
RU2141351C1 (en
Inventor
Бэран Джордж
Original Assignee
Траделл Медикал Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Траделл Медикал Лимитед filed Critical Траделл Медикал Лимитед
Publication of RU95109450A publication Critical patent/RU95109450A/en
Application granted granted Critical
Publication of RU2141351C1 publication Critical patent/RU2141351C1/en

Links

Claims (68)

1. Способ доставки лекарственного средства в дыхательную систему пациента, предусматривающий размещение интубационной трубки в дыхательной системе пациента, отличающийся тем, что размещают распыляющий катетер в дыхательной системе пациента и используют распыляющий катетер для получения аэрозоля лекарственного средства у дистального конца распыляющего катетера, при этом интубационная трубка находится в дыхательной системе пациента.1. A method of delivering a drug to the patient’s respiratory system, comprising placing an endotracheal tube in the patient’s respiratory system, characterized in that a nebulizing catheter is placed in the patient’s respiratory system and a nebulizing catheter is used to produce a drug aerosol at the distal end of the nebulizing catheter, wherein the endotracheal tube located in the respiratory system of the patient. 2. Способ по п.1, отличающийся тем, что использование распыляющего катетера далее включает подачу жидкого лекарственного средства к первому отверстию, расположенному у дистального конца распыляющего катетера, и подачу сжатого газа к второму отверстию, расположенному у дистального конца распыляющего катетера рядом с первым отверстием, для получения аэрозоля жидкого лекарственного средства у первого отверстия. 2. The method according to claim 1, characterized in that the use of a nebulizing catheter further includes supplying liquid medicine to a first opening located at the distal end of the nebulizing catheter, and supplying compressed gas to a second opening located at the distal end of the nebulizing catheter near the first opening , to obtain an aerosol of a liquid drug at the first hole. 3. Способ по п.1, отличающийся тем, что использование распыляющего катетера далее включает подсоединение контейнера под давлением, содержащего смесь лекарственного средства и жидкого газа-вытеснителя, к проксимальному концу распыляющего катетера, подачу смеси лекарственного средства и жидкого газа-вытеснителя через первый канал распыляющего катетера к первому дистальному отверстию, расположенному у дистального конца распыляющего катетера, и подачу сжатого газа через второй канал распыляющего катетера к второму отверстию, расположенному у дистального конца распыляющего катетера в непосредственной близости от первого отверстия для усиления процесса образования аэрозоля из лекарственного средства, поступающего из первого отверстия. 3. The method according to claim 1, characterized in that the use of a nebulizing catheter further includes connecting a pressure container containing a mixture of the drug and the liquid propellant to the proximal end of the nebulizing catheter, feeding the mixture of the drug and the liquid propellant through the first channel a nebulizing catheter to a first distal opening located at the distal end of the nebulizing catheter, and supplying compressed gas through a second channel of the nebulizing catheter to a second opening at the distal end of the nebulizing catheter in the immediate vicinity of the first opening to enhance the process of aerosol formation from the drug coming from the first opening. 4. Способ по п.3, отличающийся тем, что сжатый газ из второго отверстия направляют навстречу лекарственному средству и газу-распылителю, подаваемым из первого дистального отверстия. 4. The method according to claim 3, characterized in that the compressed gas from the second hole is directed towards the drug and the nebulizer gas supplied from the first distal hole. 5. Способ по п. 1, отличающийся тем, что осуществляют центрирование распыляющего катетера в интубационной трубке. 5. The method according to p. 1, characterized in that they center the nebulizing catheter in the endotracheal tube. 6. Способ по п.1, отличающийся тем, что размещение распыляющего катетера осуществляют через вспомогательный канал интубационной трубки. 6. The method according to claim 1, characterized in that the placement of the nebulizing catheter is carried out through the auxiliary channel of the endotracheal tube. 7. Способ по п.1, отличающийся тем, что осуществляют извлечение распыляющего катетера, в то время как интубационная трубка остается размещенной в дыхательной системе пациента. 7. The method according to claim 1, characterized in that the extraction of the nebulizing catheter is carried out, while the endotracheal tube remains located in the patient's respiratory system. 8. Способ по п.2, отличающийся тем, что создают пульсацию доставляемой жидкости. 8. The method according to claim 2, characterized in that it creates a pulsation of the delivered fluid. 9. Способ по п.8, отличающийся тем, что пульсацию осуществляют с частотой более 100 Гц. 9. The method according to claim 8, characterized in that the ripple is carried out with a frequency of more than 100 Hz. 10. Способ по п.8, отличающийся тем, что пульсацию прикладывают к проксимальному резервуару, на которого подают жидкое лекарственное средство. 10. The method according to claim 8, characterized in that the pulsation is applied to the proximal reservoir, which serves the liquid drug. 11. Способ по п.8, отличающийся тем, что пульсация связана с подачей менее 10 мл жидкого лекарственного средства. 11. The method according to claim 8, characterized in that the pulsation is associated with the supply of less than 10 ml of a liquid drug. 12. Способ по п. 1, отличающийся тем, что использование распыляющего катетера далее включает подачу электрического сигнала к дистальному концу распыляющего катетера для генерирования аэрозоля у указанного дистального конца. 12. The method according to p. 1, characterized in that the use of a nebulizing catheter further includes applying an electrical signal to the distal end of the nebulizing catheter to generate an aerosol at said distal end. 13. Способ по п.1, отличающийся тем, что осуществляют подачу коаксиального потока воздуха к дистальному концу распыляющего катетера, вызывая образование аэрозоля у дистального конца. 13. The method according to claim 1, characterized in that the supply of a coaxial air flow to the distal end of the nebulizing catheter, causing the formation of aerosol at the distal end. 14. Способ по п.1, отличающийся тем, что осуществляют увлажнение дыхательной системы пациента. 14. The method according to claim 1, characterized in that the hydration of the respiratory system of the patient. 15. Способ по п.1, отличающийся тем, что осуществляют: балансирование потока воздуха у дистального конца распыляющего катетера путем удаления воздуха через канал для подачи вакуума, проходящий через распыляющий катетер. 15. The method according to claim 1, characterized in that they carry out: balancing the air flow at the distal end of the nebulizing catheter by removing air through the channel for supplying vacuum passing through the nebulizing catheter. 16. Способ по п.1, отличающийся тем, что размещение распыляющего катетера далее включает получение сигнала о размещении распыляющего катетера относительно интубационной трубки. 16. The method according to claim 1, characterized in that the placement of the nebulizing catheter further includes receiving a signal on the placement of the nebulizing catheter relative to the endotracheal tube. 17. Способ по п.16, отличающийся тем, что сигнал является тактильным сигналом. 17. The method according to clause 16, wherein the signal is a tactile signal. 18. Способ по п.16, отличающийся тем, что получение сигнала далее включает получение сигнала об изменении давления у дистального конца интубационной трубки, как только мимо него проходит дистальный конец распыляющего катетера. 18. The method according to clause 16, wherein the signal further includes receiving a signal about the change in pressure at the distal end of the endotracheal tube as soon as the distal end of the nebulizing catheter passes by it. 19. Способ доставки лекарственного средства в одно или оба легких пациента, которому не вставлена интубационная трубка, отличающийся тем, что размещают распыляющий катетер в дыхательной системе пациента и используют его для получения аэрозоля лекарственного средства у дистального конца. 19. A method for delivering a drug to one or both lungs of a patient to whom an endotracheal tube is not inserted, characterized in that a nebulizing catheter is placed in the patient's respiratory system and used to obtain a drug aerosol at the distal end. 20. Способ доставки аэрозоля лекарственного средства в легкие пациента, отличающийся тем, что распыляют лекарственное средство у дистального конца катетера, размещенного в респираторном тракте пациента, при этом дистальный конец катетера нацелен в первом направлении, и нацеливают поток газа на распыленное лекарственное средство в направлении, противоположном первому. 20. A method for delivering a drug aerosol to the patient’s lungs, characterized in that the drug is sprayed at the distal end of the catheter located in the patient’s respiratory tract, the distal end of the catheter being aimed in the first direction, and the gas flow is directed towards the nebulized drug in the direction opposite to the first. 21. Способ по п.20, отличающийся тем, что первое направление на стадии распыления является дистальным направлением. 21. The method according to claim 20, characterized in that the first direction at the stage of spraying is a distal direction. 22. Способ по п.20, отличающийся тем, что первое направление на стадии распыления является проксимальным направлением. 22. The method according to claim 20, characterized in that the first direction at the stage of spraying is the proximal direction. 23. Способ по п.20, отличающийся тем, что стадия нацеливания характеризуется направлением потока газа от дистального конца интубационной трубки. 23. The method according to claim 20, characterized in that the targeting stage is characterized by the direction of the gas flow from the distal end of the endotracheal tube. 24. Способ по п.20, отличающийся тем, что указанный поток газа образован потоком воздуха при вдохе пациента через интубационную трубку. 24. The method according to claim 20, characterized in that said gas stream is formed by an air stream when the patient is inhaled through an endotracheal tube. 25. Способ доставки лекарственного средства к разветвленному участку дыхательной системы пациента, отличающийся тем, что размещают катетер в ветвь дыхательной системы человека, которая ведет к участку, отличному от участка, к которому будет доставляться лекарственное средство, подают поток воздуха через катетер, и распыляют лекарственное средство в дыхательной системе проксимально от того места, куда направляется поток воздуха, при этом поток распыленного лекарственного средства подают на участок без катетера. 25. A method for delivering a drug to a branched section of a patient’s respiratory system, characterized in that the catheter is placed in a branch of the human respiratory system, which leads to a section other than the site to which the drug will be delivered, an air stream is passed through the catheter, and the drug is sprayed means in the respiratory system proximally from the place where the air stream is directed, while the stream of nebulized drug is delivered to the site without a catheter. 26. Катетер для доставки аэрозоля лекарственного средства в легкие пациента, отличающийся тем, что имеет штифт катетера, выполненный с проксимальным концом и дистальным концом, канал по штифту катетера и соединение у проксимального конца с входным каналом для приема лекарственного средства в жидкой форме и соединение у дистального конца с дистальным отверстием, из которого выходит лекарственное средство, приспособление для распыления лекарственного средства, выходящего из дистального отверстия, для получения потока аэрозоля, состоящего из частиц лекарственного средства, и устройство для модификации потока аэрозоля, состоящего из частиц лекарственного средства. 26. A catheter for delivering an aerosol of a drug to the patient’s lungs, characterized in that it has a catheter pin made with a proximal end and a distal end, a channel along the catheter pin and a connection at the proximal end with an inlet for receiving the drug in liquid form and connection to the distal end with a distal opening from which the drug exits, a device for spraying the drug exiting the distal opening to obtain an aerosol stream consisting o of drug particles, and a device for modifying an aerosol stream consisting of drug particles. 27. Катетер по п. 26, отличающийся тем, что модифицирующее устройство включает отверстие для подачи вакуума рядом с дистальным отверстием, из которого выходит лекарственное средство, для удаления воздуха из распыленного аэрозоля. 27. The catheter according to claim 26, characterized in that the modifying device includes a hole for supplying a vacuum next to the distal opening from which the drug exits to remove air from the spray aerosol. 28. Катетер по п. 26, отличающийся тем, что модифицирующее устройство выполнено с приспособлением для уменьшения скорости частиц. 28. The catheter according to claim 26, characterized in that the modifying device is made with a device for reducing the speed of particles. 29. Катетер по п. 26, отличающийся тем, что модифицирующее устройство выполнено с приспособлением для увеличения ширины потока аэрозоля. 29. The catheter according to p. 26, characterized in that the modifying device is made with a device for increasing the width of the aerosol stream. 30. Катетерная система для доставки аэрозоля лекарственного средства в легкие пациента, отличающаяся тем, что имеет штифт катетера, выполненный проксимальным концом и дистальным концом, проходящий через штифт канал, соединяющийся у проксимального конца с входным каналом для введения лекарственного средства в жидкой форме и соединяющийся у дистального конца с дистальным отверстием, из которого может выводиться лекарственное средство, устройство для распыления лекарственного средства, которое выводится из дистального отверстия, устройство для управления потоком, соединенное с входным каналом, выполненное с проточной линией, связанной с входным отверстием, при этом проточная линия заполнена лекарственным препаратом, и вентилем, соединенным с проточной линией, для вызова пульсирующей подачи лекарственного средства через проточную линию. 30. A catheter system for delivering an aerosol of a drug to the patient’s lungs, characterized in that it has a catheter pin made with a proximal end and a distal end, passing through a pin channel connecting at the proximal end to the drug input channel in liquid form and connecting at the distal end with a distal opening from which the drug can be withdrawn, a device for spraying the drug, which is removed from the distal opening, the device GUT flow control connected to said inlet configured flow line connected to the inlet, wherein the flow line is filled with medicament and a valve connected to the flow line, to call a pulsating flow of drug through the flowline. 31. Катетерная система по п.30, отличающаяся тем, что устройство для управления потоком выполнено с участком возврата жидкости, связанным с проточной линией, при этом участок возврата жидкости организован таким образом, чтобы вызвать обратный поток жидкости через контроллер проточной линии, синхронизированный с пульсирующей подачей жидкости. 31. The catheter system according to claim 30, wherein the flow control device is configured with a fluid return portion connected to the flow line, wherein the fluid return portion is arranged so as to induce a reverse fluid flow through the flow line controller synchronized with the pulsating fluid supply. 32. Катетер для доставки аэрозоля в легкие пациента, отличающийся тем, что имеет штифт, выполненный с внешним цилиндрическим элементом конструкции, ограничивающим первый канал и заканчивающимся у дистального конца в первом дистальном отверстии, внутренним цилиндрическим элементом конструкции, ограничивающим второй канал, при этом внутренний цилиндрический элемент конструкции размещен в первом канале и заканчивается у дистального конца во втором дистальном отверстии, патрубком, присоединенным к проксимальному концу штифта, выполненным с первым входным каналом, связанным с первым каналом для подачи сжатого газа во внутренней области между внутренними и внешним цилиндрическими элементами конструкции, и вторым входным каналом, соединяющимся с вторым каналом для подачи жидкого лекарственного средства, при этом второе дистальное отверстие ориентировано относительно первого дистального отверстия, для распыления лекарственного средства из дистального кончика катетера. 32. A catheter for delivering an aerosol to the patient’s lungs, characterized in that it has a pin made with an external cylindrical structural element defining the first channel and ending at the distal end in the first distal opening, with an internal cylindrical structural element defining the second channel, while the inner cylindrical the structural element is placed in the first channel and ends at the distal end in the second distal hole, a pipe connected to the proximal end of the pin, made m with a first inlet channel connected to the first channel for supplying compressed gas in the inner region between the inner and outer cylindrical structural elements, and a second inlet channel connecting to the second channel for supplying liquid medicine, while the second distal opening is oriented relative to the first distal opening , for spraying the drug from the distal tip of the catheter. 33. Катетер по п.32, отличающийся тем, что имеет способный извлекаться стержень, размещенный во втором канале. 33. The catheter according to claim 32, characterized in that it has a removable shaft located in the second channel. 34. Катетер для доставки аэрозоля лекарственного средства в легкие пациента, отличающийся тем, что имеет штифт, содержащий первый канал, расположенный в центре штифта и приспособленный для доставки жидкого лекарственного препарата, множество каналов, расположенных по периферии вокруг первого канала и приспособленных для подачи газа, дистальное сопло для подачи жидкости, соединяющееся с первым каналом, и множество дистальных отверстий для подачи газа, соединенных с множеством каналов, при этом множество дистальных отверстий для подачи газа ориентировано относительно дистального отверстия для подачи жидкости таким образом, чтобы распылять жидкое лекарственное средство, выделяемое из канала для подачи жидкости. 34. A catheter for delivering an aerosol of a drug to the lungs of a patient, characterized in that it has a pin containing a first channel located in the center of the pin and adapted to deliver a liquid drug, a plurality of channels located peripherally around the first channel and adapted to supply gas, a distal fluid supply nozzle connecting to the first channel and a plurality of distal gas supply openings connected to the plurality of channels, the plurality of distal supplying holes r for oriented relative to the distal opening of the liquid feed so as to atomize the liquid medication is isolated from the liquid supply channel. 35. Катетерная система для доставки аэрозольной терапии в легкие пациента, отличающаяся тем, что имеет автономный распыляющий катетер, выполненный с дистальным концом для размещения в дыхательной системе пациента и проксимальным концом, при этом автономный распыляющий катетер включает штифт катетера, канал для подачи сжатого газа, проходящий через штифт катетера, дистальное отверстие для выхода газа, связанное с каналом для подачи сжатого газа, причем дистальное отверстие для выхода газа расположено у дистального конца распыляющего катетера, канал для подачи лекарства, проходящий вдоль по крайней мере части штифта катетера, и дистальное отверстие для подачи лекарства, соединенное с каналом для доставки лекарства, причем дистальное отверстие для подачи лекарства размещено в непосредственной близости от дистального отверстия для выхода газа так, что газ, поступающий из дистального отверстия для выхода газа, распыляет лекарство, подаваемое из дистального отверстия для подачи лекарства. 35. A catheter system for delivering aerosol therapy to the patient’s lungs, characterized in that it has a self-contained nebulizing catheter made with a distal end for placement in the patient’s respiratory system and a proximal end, wherein the self-contained nebulizing catheter includes a catheter pin, a channel for supplying compressed gas, passing through the catheter pin, a distal gas outlet, connected to a channel for supplying compressed gas, and a distal gas outlet is located at the distal end of the nebulizing cat ethera, a drug supply passage extending along at least a portion of the catheter pin, and a distal drug delivery port connected to the drug delivery channel, the distal drug delivery port being located in close proximity to the distal gas outlet port so that the gas coming from the distal opening for the exit of gas, sprays the medicine supplied from the distal opening for the supply of medicine. 36. Катетерная система по п.35, отличающаяся тем, что имеет интубационную трубку, выполненную с вентиляционным каналом, по которому может перемещаться распыляющий катетер. 36. The catheter system according to clause 35, characterized in that it has an endotracheal tube made with a ventilation channel through which the nebulizing catheter can move. 37. Катетерная система по п.35, отличающаяся тем, что имеет интубационную трубку, выполненную с вентиляционным каналом и вспомогательным каналом, расположенным рядом с вентиляционным каналом, при этом вспомогательный канал имеет дистальное отверстие в вентиляционный канал, так что дистальный конец вспомогательного канала выходит в вентиляционный канал рядом с его дистальным концом, а распыляющий катетер выполнен с возможностью прохода через вспомогательный канал. 37. The catheter system according to clause 35, characterized in that it has an endotracheal tube made with a ventilation channel and an auxiliary channel located next to the ventilation channel, while the auxiliary channel has a distal opening in the ventilation channel, so that the distal end of the auxiliary channel goes into a ventilation channel near its distal end, and a nebulizing catheter is configured to pass through an auxiliary channel. 38. Катетерная система по п.35, отличающаяся тем, что имеет центрирующее устройство, размещенное на штифте катетера близко к дистальному концу. 38. The catheter system according to clause 35, characterized in that it has a centering device placed on the pin of the catheter close to the distal end. 39. Катетерная система по п.35, отличающаяся тем, что имеет центрирующее устройство, имеет размер в расширенном состоянии и размер в сжатом состоянии, причем, оно принимает размер в расширенном состоянии, тогда когда оно развертывается в воздушном проходе. 39. The catheter system according to claim 35, characterized in that it has a centering device, has a size in an expanded state and a size in a compressed state, moreover, it takes a size in an expanded state when it is deployed in an air passage. 40. Катетерная система по п.35, отличающаяся тем, что центрирующее устройство имеет более одного размера в расширенном состоянии. 40. The catheter system according to clause 35, wherein the centering device has more than one size in the expanded state. 41. Катетерная система по п.35, отличающаяся тем, что центрирующее устройство имеет размер в расширенном состоянии, который может быть скорректирован после развертывания. 41. The catheter system according to clause 35, wherein the centering device has a size in the expanded state, which can be adjusted after deployment. 42. Катетерная система по п.35, отличающаяся тем, что центрирующее устройство включает газовые отверстия для центрирования. 42. The catheter system according to clause 35, wherein the centering device includes gas holes for centering. 43. Катетерная система по п.35, отличающаяся тем, что распыляющий катетер включает клапан, размещенный по крайней мере в одном из каналов. 43. The catheter system according to clause 35, wherein the nebulizing catheter includes a valve located in at least one of the channels. 44. Катетерная система по п.43, отличающаяся тем, что клапан размещен по крайней мере в одном из дистальных отверстий. 44. The catheter system according to item 43, wherein the valve is placed in at least one of the distal openings. 45. Катетерная система по п.43, отличающаяся тем, что клапан выполнен с возможностью управления от проксимального конца распыляющего катетера. 45. The catheter system according to item 43, wherein the valve is operable from the proximal end of the nebulizing catheter. 46. Катетерная система по п.43, отличающаяся тем, что клапан выполнен с возможностью привода в действие дистального конца катетера. 46. The catheter system according to item 43, wherein the valve is configured to drive the distal end of the catheter. 47. Катетерная система по п.43, отличающаяся тем, что клапан образован эластично закрывающимся кончиком. 47. The catheter system according to item 43, wherein the valve is formed by an elastically closing tip. 48. Катетерная система по п.35, отличающаяся тем, что имеет ограничитель на проксимальной части штифта катетера. 48. The catheter system according to clause 35, characterized in that it has a stopper on the proximal part of the catheter pin. 49. Катетерная система по п.35, отличающаяся тем, что имеет градуированные метки на штифте катетера. 49. The catheter system according to clause 35, characterized in that it has graduated marks on the pin of the catheter. 50. Катетерная система по п.35, отличающаяся тем, что имеет замковые соединители люерного типа на проксимальных входных каналах, соединенных с каналом для подачи сжатого газа и каналом для подачи лекарства. 50. The catheter system according to clause 35, characterized in that it has luer-type locking connectors on the proximal inlet channels connected to the channel for supplying compressed gas and the channel for supplying medication. 51. Катетерная система по п.35, отличающаяся тем, что имеет самозакрывающиеся проксимальные входные каналы, соединенные с каналом для подачи сжатого газа и каналом для подачи лекарства. 51. The catheter system according to claim 35, characterized in that it has self-closing proximal inlet channels connected to a channel for supplying compressed gas and a channel for delivering medicine. 52. Катетерная система по п.35, отличающаяся тем, что имеет средство для очистки от закупорок у дистального конца катетера. 52. The catheter system according to clause 35, characterized in that it has a means for cleaning from blockages at the distal end of the catheter. 53. Катетерная система по п.35, отличающаяся тем, что имеет способный извлекаться стержень, расположенный по крайней мере в одном из указанных каналов. 53. The catheter system according to clause 35, characterized in that it has a removable rod located in at least one of these channels. 54. Катетерная система по п.35, отличающаяся тем, что имеет полоску на штифте катетера. 54. The catheter system according to clause 35, characterized in that it has a strip on the pin of the catheter. 55. Катетерная система по п.35, отличающаяся тем, что имеет дефлектор, размещенный у дистального конца распыляющего катетера перед отверстиями. 55. The catheter system according to clause 35, characterized in that it has a deflector located at the distal end of the nebulizing catheter in front of the holes. 56. Катетерная система по п.35, отличающаяся тем, что штифт катетера включает проходящий через него третий канал и оптический волновод, проходящий через указанный третий канал. 56. The catheter system according to clause 35, wherein the catheter pin includes a third channel passing through it and an optical waveguide passing through the specified third channel. 57. Катетерная система по п.35, отличающаяся тем, что по крайней мере часть штифта, окружающего канал для доставки лекарства, изготовлена из материала, обладающего низкой эластичностью, так что контроль у дистального отверстия для выделения лекарства за потоком жидкости, поступающей по каналу для доставки лекарства, более важен, чем контроль за потоком у его дистального конца. 57. The catheter system according to clause 35, wherein at least a portion of the pin surrounding the drug delivery channel is made of a material having low elasticity, so that the control at the distal opening to isolate the drug for fluid flow entering the channel for drug delivery is more important than controlling the flow at its distal end. 58. Катетерная система по п.35, отличающаяся тем, что имеет вибрирующий материал, размещенный рядом с дистальным отверстием. 58. The catheter system according to clause 35, characterized in that it has a vibrating material located next to the distal opening. 59. Катетерная система по п.53, отличающаяся тем, что вибрирующий материал является пьезоэлектрическим материалом, который соединен с по крайней мере одним электрическим проводником, проходящим через штифт катетера. 59. The catheter system according to item 53, wherein the vibrating material is a piezoelectric material that is connected to at least one electrical conductor passing through the pin of the catheter. 60. Дренажный катетер для использования в интубационной трубке, размер которого подбирается таким, чтобы его можно было разместить в вентиляционном канале интубационной трубки, выполненный с аспирационным каналом для удаления слизи из респираторного тракта пациента, которому введена интубационная трубка, отличающийся тем, что имеет канал для подачи сжатого газа, проходящий по стенке дренажного канала рядом с аспирационным каналом, дистальное отверстие для выхода газа, соединяющееся с каналом для подачи сжатого газа и размещенное у дистального конца дренажного катетера, канал для подачи лекарства, проходящий по стенке дренажного катетера рядом с аспирационным каналом, и дистальное отверстие для подачи лекарства, соединенное с каналом для подачи жидкости, при этом отверстие для подачи лекарства размещено проксимально к дистальному отверстию для выхода газа, так что газ, выходящий из дистального отверстия для выхода газа, распыляет лекарство, выделяемое из дистального отверстия для подачи лекарства. 60. A drainage catheter for use in an endotracheal tube, the size of which is selected so that it can be placed in the ventilation duct of the endotracheal tube, made with an aspiration channel for removing mucus from the respiratory tract of the patient to whom the endotracheal tube is inserted, characterized in that it has a channel for compressed gas supply, passing along the wall of the drainage channel near the suction channel, a distal gas outlet for connecting to the channel for supplying compressed gas and located at the dist the far end of the drainage catheter, a drug supply passage extending along the wall of the drainage catheter next to the suction channel, and a distal drug delivery port connected to the fluid supply channel, wherein the drug delivery port is positioned proximal to the distal gas outlet, that the gas exiting the distal gas outlet is spraying the drug released from the distal drug delivery port. 61. Дренажный катетер по п.60, отличающийся тем, что дистальное отверстие для выхода газа и дистальное отверстие для подачи лекарства ориентированы проксимально относительно дистального дренажного отверстия, которое соединено с аспирационным каналом. 61. The drainage catheter according to claim 60, characterized in that the distal gas outlet and the distal drug delivery opening are oriented proximal to the distal drainage hole that is connected to the suction channel. 62. Дренажный катетер по п.60, отличающийся тем, что дистальное отверстие для выхода газа и дистальное отверстие для подачи лекарства ориентированы радиально относительно оси дренажного катетера. 62. The drainage catheter according to claim 60, characterized in that the distal gas outlet and the distal drug delivery opening are oriented radially relative to the axis of the drainage catheter. 63. Способ изготовления катетера для распыления жидкости с помощью газа, имеющий близко расположенные дистальные отверстия, размеры которых и расстояния между которыми выполнены с малыми допусками, отличающийся тем, что получают методом экструзии полимерную многоканальную трубку с относительно большими размерами, нагревают часть трубки до температуры перехода указанной трубки, осуществляют вытяжку указанной части трубки для получения конусообразной части с величиной вытяжки в интервале от 2 к 1 до 20 к 1, так что каналы в конусообразной части все более сближаются между собой, и формируют множество отверстий у дистального конца конусообразной части, при этом размер множества отверстий подбирают таким образом, чтобы распылять жидкость, поступающую по одному из указанных каналов, с образованием аэрозоля с помощью газа, подаваемого по другому из указанных каналов. 63. A method of manufacturing a catheter for spraying a liquid with a gas, having closely spaced distal openings, the dimensions of which and the distances between them are made with small tolerances, characterized in that the polymer multichannel tube with relatively large dimensions is obtained by extrusion, heat a portion of the tube to a transition temperature the specified tube, carry out the extraction of the specified part of the tube to obtain a cone-shaped part with a drawdown in the range from 2 to 1 to 20 to 1, so that the channels in the cone-shaped h The parts are becoming closer to each other and forming many holes at the distal end of the cone-shaped part, while the size of the many holes is selected in such a way as to spray the liquid coming through one of these channels, with the formation of aerosol using gas supplied through the other from these channels . 64. Способ по п.63, отличающийся тем, что формирование множества отверстий далее включает разрезание дистального конца конусообразной части. 64. The method according to item 63, wherein the formation of multiple holes further includes cutting the distal end of the cone-shaped part. 65. Способ по п.63, отличающийся тем, что осуществляют разрезание трубки до нужного размера, для получения штифтовой части распыляющего катетера. 65. The method according to p, characterized in that they cut the tube to the desired size, to obtain the pin part of the nebulizing catheter. 66. Способ по п.63, отличающийся тем, что воздействуют радиацией высокой энергии на часть указанной трубки. 66. The method according to p, characterized in that they are exposed to high energy radiation on a part of the specified tube. 67. Способ по п. 63, отличающийся тем, что катетер используют в дыхательной системе. 67. The method according to p. 63, characterized in that the catheter is used in the respiratory system. 68. Способ по п.63, отличающийся тем, что нагревание далее включает нагревание трубки до температуры в интервале от расплавленного состояния до ее стеклообразного состояния. 68. The method according to p, characterized in that the heating further includes heating the tube to a temperature in the range from the molten state to its glassy state.
RU95109450/14A 1994-06-17 1995-06-16 Method of delivery of medicine to patient's respiratory system; method of delivery of medicine to one or two patient's lungs into which no intubation tube is installed; method of delivery of medicine aerosol to patient's lungs; method of delivery of medicine to branching part of patient's respiratory system; catheter for delivery of medicine aerosol to patient's lung (versions); catheter system for delivery of medicine aerosol to patient's lungs; catheter system for delivery of aerosol therapy to patient's lungs draining catheter for use in intubation tube and method of manufacture of catheter for spraying liquid by means of gas RU2141351C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26186694A 1994-06-17 1994-06-17
US08/261,866 1994-06-17
US08/261866 1994-06-17

Publications (2)

Publication Number Publication Date
RU95109450A true RU95109450A (en) 1997-11-10
RU2141351C1 RU2141351C1 (en) 1999-11-20

Family

ID=22995221

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95109450/14A RU2141351C1 (en) 1994-06-17 1995-06-16 Method of delivery of medicine to patient's respiratory system; method of delivery of medicine to one or two patient's lungs into which no intubation tube is installed; method of delivery of medicine aerosol to patient's lungs; method of delivery of medicine to branching part of patient's respiratory system; catheter for delivery of medicine aerosol to patient's lung (versions); catheter system for delivery of medicine aerosol to patient's lungs; catheter system for delivery of aerosol therapy to patient's lungs draining catheter for use in intubation tube and method of manufacture of catheter for spraying liquid by means of gas

Country Status (13)

Country Link
US (3) US5964223A (en)
EP (2) EP1433493B1 (en)
JP (3) JP3746090B2 (en)
KR (1) KR960000256A (en)
AT (2) ATE527009T1 (en)
AU (1) AU700225B2 (en)
BR (1) BR9502836A (en)
CA (1) CA2152002C (en)
DE (1) DE69532843T2 (en)
IL (1) IL114154A0 (en)
NZ (1) NZ272354A (en)
RU (1) RU2141351C1 (en)
ZA (1) ZA954936B (en)

Families Citing this family (356)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676627B1 (en) * 1990-08-06 2004-01-13 Possis Medical, Inc. Crossflow thrombectomy catheter and system
US5642730A (en) * 1994-06-17 1997-07-01 Trudell Medical Limited Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister
ZA954936B (en) * 1994-06-17 1996-02-27 Trudell Medical Ltd Nebulizing catheter system and methods of use and manufacture
US6729334B1 (en) * 1994-06-17 2004-05-04 Trudell Medical Limited Nebulizing catheter system and methods of use and manufacture
SE9503141D0 (en) * 1995-09-12 1995-09-12 Siemens Elema Ab Anesthesia apparatus
FR2758089B1 (en) * 1997-01-06 1999-03-05 Georges Boussignac METHOD AND DEVICE FOR EXCHANGING RESPIRATORY TUBE IN THE TRACHEA OF A PATIENT
US6432986B2 (en) 1997-07-21 2002-08-13 Bruce H. Levin Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US6016800A (en) * 1997-10-24 2000-01-25 Century; Theodore J. Intrapulmonary aerosolizer
US6167883B1 (en) * 1998-01-23 2001-01-02 Respiratory Support Products, Inc. Medical air hose internal flow heater
EP2289423A1 (en) * 1998-05-14 2011-03-02 David N. Krag System for bracketing tissue
US6319248B1 (en) * 1998-07-29 2001-11-20 Cryocath Technologies, Inc. Spray catheter
SE512807C2 (en) * 1998-09-02 2000-05-15 Bjoern Flodin Device for supplying inhalation gas to and removing exhalation gas from a patient
AU2862200A (en) * 1999-01-27 2000-08-18 Bruce H. Levin Compositions, kits, apparatus, and methods for inhibiting cerebral neurovasculardisorders and muscular headaches
US8506519B2 (en) 1999-02-16 2013-08-13 Flowcardia, Inc. Pre-shaped therapeutic catheter
US6855123B2 (en) 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US7018365B2 (en) 1999-05-21 2006-03-28 Micro Therapeutics, Inc. Threaded syringe with quick stop
US6415788B1 (en) * 1999-07-02 2002-07-09 Enternet Medical, Inc. Apparatus for treating respiratory gases including liquid trap
US6976489B2 (en) 2000-06-30 2005-12-20 Northgate Technologies, Inc. Method and apparatus for humidification and warming of air
CA2743952C (en) 2000-06-30 2013-04-30 Northgate Technologies Inc. Method and apparatus for humidification and warming of air
US6464662B1 (en) 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US6536423B2 (en) * 2000-08-14 2003-03-25 Patrick J Conway Patient activated mouth moisturizer
FR2813197B1 (en) 2000-08-22 2003-08-08 Georges Boussignac RESPIRATORY ASSISTANCE DEVICE WITH ADMINISTRATION OF NEBULIZED PRODUCTS
US6706017B1 (en) * 2000-09-18 2004-03-16 Pavel Dulguerov Percutaneous ostomy device and method for creating a stoma and implanting a canula
CA2427628C (en) * 2000-11-03 2010-03-16 The Cleveland Clinic Foundation Catheter for removal of solids from surgical drains
ATE456332T1 (en) * 2000-11-17 2010-02-15 Calypso Medical Inc SYSTEM FOR LOCALIZING AND DEFINING A TARGET POSITION IN A HUMAN BODY
US8235919B2 (en) 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
US6517492B2 (en) 2001-02-22 2003-02-11 Texon Technologies Ltd. Method and apparatus for assessment of cardiac function by monitoring movement of the trachea
US20020132013A1 (en) * 2001-03-14 2002-09-19 Harry Moulis Liquid cautery catheter
JP2004524933A (en) * 2001-04-11 2004-08-19 カンドラー ミヒャエル Artificial respirator
US6905489B2 (en) 2001-04-24 2005-06-14 Northgate Technologies, Inc. Laparoscopic insertion device
US20030051733A1 (en) * 2001-09-10 2003-03-20 Pulmonx Method and apparatus for endobronchial diagnosis
US7883471B2 (en) 2001-09-10 2011-02-08 Pulmonx Corporation Minimally invasive determination of collateral ventilation in lungs
US20050245944A1 (en) * 2002-02-01 2005-11-03 Rezai Ali R Apparatus for facilitating delivery of at least one device to a target site in a body
FR2836384B1 (en) 2002-02-27 2004-12-10 Georges Boussignac RESPIRATORY ASSISTANCE DEVICE
US6698429B2 (en) * 2002-03-15 2004-03-02 Wolfe Tory Medical, Inc. Medical atomizer
US8245708B2 (en) * 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
US7607436B2 (en) * 2002-05-06 2009-10-27 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
EP2647400A1 (en) 2002-05-07 2013-10-09 The State University of New York at Stony Brook Devices for targeted endobronchial therapy
US6918391B1 (en) * 2002-05-20 2005-07-19 Johnny V. Moore Multi-lumen endotracheal tube
US20030226566A1 (en) * 2002-06-06 2003-12-11 Dhuper Sunil Kumar Endotracheal tube with aerosol delivery apparatus II
US8074649B2 (en) * 2002-07-18 2011-12-13 Aeon Research And Technology, Inc. Endotracheal tube with feature for delivering aerosolized medication
US9955994B2 (en) 2002-08-02 2018-05-01 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US8133236B2 (en) 2006-11-07 2012-03-13 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US7335180B2 (en) 2003-11-24 2008-02-26 Flowcardia, Inc. Steerable ultrasound catheter
US7220233B2 (en) 2003-04-08 2007-05-22 Flowcardia, Inc. Ultrasound catheter devices and methods
US7604608B2 (en) * 2003-01-14 2009-10-20 Flowcardia, Inc. Ultrasound catheter and methods for making and using same
US7137963B2 (en) 2002-08-26 2006-11-21 Flowcardia, Inc. Ultrasound catheter for disrupting blood vessel obstructions
US6942677B2 (en) 2003-02-26 2005-09-13 Flowcardia, Inc. Ultrasound catheter apparatus
ES2357566T3 (en) * 2002-09-06 2011-04-27 Philip Morris Usa Inc. AEROSOL GENERATING DEVICES AND METHODS FOR GENERATING AEROSOLS WITH CONTROLLED PARTICLE SIZES.
US7204248B2 (en) * 2002-09-27 2007-04-17 Cook Critical Care Incorporated Fiberoptic nebulizer
IL152813A0 (en) * 2002-11-13 2003-06-24 Method and device for application of medical preparations to surfaces of the closed visceral cavities for example, to the pleura or the peritoneum
US20040187864A1 (en) * 2003-03-24 2004-09-30 Cindet, Llc Inhalation device and method
US20040193100A1 (en) * 2003-03-25 2004-09-30 Kimberly-Clark Worldwide, Inc. Drain assembly with a piercing member for removing liquid from a gas directing tube
US20040193101A1 (en) * 2003-03-25 2004-09-30 Kimberly-Clark Worldwide, Inc. Drain assembly for removing liquid from a gas directing tube
US7854724B2 (en) * 2003-04-08 2010-12-21 Surgiquest, Inc. Trocar assembly with pneumatic sealing
US7654975B2 (en) * 2003-04-24 2010-02-02 Northgate Technologies, Inc. Mixed-gas insufflation system
AU2004235782B2 (en) * 2003-05-02 2009-07-02 Clearflow, Inc. Body-space drainage-tube debris removal
US6766801B1 (en) * 2003-05-05 2004-07-27 Medical Device Group, Inc. Intra-tracheal aerosol delivery system and method of using same
US20040226556A1 (en) * 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US8012136B2 (en) * 2003-05-20 2011-09-06 Optimyst Systems, Inc. Ophthalmic fluid delivery device and method of operation
DE602004031829D1 (en) * 2003-05-20 2011-04-28 Collins OPHTHALMIC DRUG DELIVERY SYSTEM
WO2005042127A2 (en) * 2003-05-29 2005-05-12 Upchurch Scientific, Inc. Improved apparatus and methods for electrospray applications
US20060129091A1 (en) * 2004-12-10 2006-06-15 Possis Medical, Inc. Enhanced cross stream mechanical thrombectomy catheter with backloading manifold
US7892205B2 (en) * 2003-06-06 2011-02-22 Boston Scientific Scimed, Inc. Device and method for delivering micronized therapeutic agents in the body
DE10337138A1 (en) 2003-08-11 2005-03-17 Freitag, Lutz, Dr. Method and arrangement for the respiratory assistance of a patient as well as tracheal prosthesis and catheter
US8381729B2 (en) 2003-06-18 2013-02-26 Breathe Technologies, Inc. Methods and devices for minimally invasive respiratory support
US7588033B2 (en) * 2003-06-18 2009-09-15 Breathe Technologies, Inc. Methods, systems and devices for improving ventilation in a lung area
CN1905917B (en) 2003-08-18 2011-08-03 门罗生命公司 Method and device for non-invasive ventilation with nasal interface
US7758510B2 (en) 2003-09-19 2010-07-20 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
CA2538456C (en) 2003-10-07 2013-01-15 Northgate Technologies Inc. System and method for delivering a substance to a body cavity
US20130211320A1 (en) * 2003-10-07 2013-08-15 Nawar Alkhamesi System and method for delivering an anti-adhesive substance to a body cavity
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
CA2543680C (en) * 2003-10-31 2012-05-22 Trudell Medical International System and method for manipulating a catheter for delivering a substance to a body cavity
US8210166B2 (en) * 2003-12-16 2012-07-03 Wolfe Tory Medical, Inc. Vial multi-access adapter
US8182501B2 (en) 2004-02-27 2012-05-22 Ethicon Endo-Surgery, Inc. Ultrasonic surgical shears and method for sealing a blood vessel using same
WO2005097250A1 (en) * 2004-03-30 2005-10-20 Cook Urological Incorporated Irrigation catheter
DE102004016985B4 (en) * 2004-04-07 2010-07-22 Pari Pharma Gmbh Aerosol generating device and inhalation device
US7273050B2 (en) * 2004-05-03 2007-09-25 Huafeng Wei Jet endotracheal device and its use in intubation
US7572244B2 (en) 2004-08-02 2009-08-11 Medrad, Inc. Miniature cross stream thrombectomy catheter
WO2006016368A2 (en) * 2004-08-12 2006-02-16 Navotek Medical Ltd. Localization of a radioactive source within a body of a subject
US7540852B2 (en) 2004-08-26 2009-06-02 Flowcardia, Inc. Ultrasound catheter devices and methods
US8052592B2 (en) * 2005-09-27 2011-11-08 Evalve, Inc. Methods and devices for tissue grasping and assessment
CA2748617C (en) 2004-09-27 2014-09-23 Evalve, Inc. Methods and devices for tissue grasping and assessment
WO2006042210A2 (en) 2004-10-08 2006-04-20 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instrument
WO2006044651A1 (en) * 2004-10-15 2006-04-27 Cook Critical Care Incorporated Endobronchial blocking device having a replaceable snare
TR200403298A1 (en) * 2004-12-03 2006-02-21 Kutluhan Ahmet Mastoid antral ventilation tube
US8262605B2 (en) * 2004-12-09 2012-09-11 Ams Research Corporation Needleless delivery systems
US8221343B2 (en) 2005-01-20 2012-07-17 Flowcardia, Inc. Vibrational catheter devices and methods for making same
US8876791B2 (en) 2005-02-25 2014-11-04 Pulmonx Corporation Collateral pathway treatment using agent entrained by aspiration flow current
US7824436B2 (en) 2005-05-13 2010-11-02 Benechill, Inc. Methods and devices for non-invasive cerebral and systemic cooling
US9358150B2 (en) 2005-05-13 2016-06-07 Benechill, Inc. Methods and devices for non-invasive cerebral and systemic cooling alternating liquid mist/gas for induction and gas for maintenance
US20070016273A1 (en) * 2005-05-26 2007-01-18 Smith & Nephew, Inc. Electrothermal intervertebral disc treatment
ITBO20050404A1 (en) * 2005-06-15 2006-12-16 Sherwood Serv Ag BRONCOTRACHEAL ACCESS VALVE FOR A BRONCHOASPIRATION EQUIPMENT
DE602006016280D1 (en) * 2005-06-29 2010-09-30 Boehringer Ingelheim Int METHOD AND DEVICE FOR SPRAYING A LIQUID
DE102005030803A1 (en) * 2005-06-29 2007-01-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Atomization of liquid for medicament formulation or cosmetic agent, by directing liquid onto hot or heated contact surface to partially vaporize part of liquid, and atomizing non-vaporized liquid into small droplets to generate aerosol
US8221348B2 (en) 2005-07-07 2012-07-17 St. Jude Medical, Cardiology Division, Inc. Embolic protection device and methods of use
JP5826450B2 (en) 2005-07-22 2015-12-02 ザ ファウンドリー， エルエルシー Systems and methods for delivery of therapeutic agents
US7655243B2 (en) 2005-07-22 2010-02-02 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
US10052465B2 (en) 2005-07-22 2018-08-21 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
US8240187B2 (en) 2005-08-16 2012-08-14 Oridion Medical (1987) Ltd. Breath sampling device and method for using same
US8116858B2 (en) * 2005-08-22 2012-02-14 John Koblanski Methods and apparatus for monitoring heart motions
EP1932920A4 (en) * 2005-09-02 2009-04-08 Eisai R&D Man Co Ltd Method for screening of substance effective on disease using gpr120 and phospholipase
US7533670B1 (en) 2005-09-20 2009-05-19 Breathe Technologies, Inc. Systems, methods and apparatus for respiratory support of a patient
US8012117B2 (en) * 2007-02-06 2011-09-06 Medrad, Inc. Miniature flexible thrombectomy catheter
US7326183B2 (en) * 2005-09-28 2008-02-05 Alcon, Inc. Intraocular pressure control
US20080188793A1 (en) 2007-02-06 2008-08-07 Possis Medical, Inc. Miniature flexible thrombectomy catheter
US20070191713A1 (en) 2005-10-14 2007-08-16 Eichmann Stephen E Ultrasonic device for cutting and coagulating
US8246642B2 (en) * 2005-12-01 2012-08-21 Ethicon Endo-Surgery, Inc. Ultrasonic medical instrument and medical instrument connection assembly
US8523782B2 (en) 2005-12-07 2013-09-03 Pulmonx Corporation Minimally invasive determination of collateral ventilation in lungs
US20070167965A1 (en) * 2006-01-05 2007-07-19 Ethicon Endo-Surgery, Inc. Ultrasonic medical instrument
US7621930B2 (en) * 2006-01-20 2009-11-24 Ethicon Endo-Surgery, Inc. Ultrasound medical instrument having a medical ultrasonic blade
US20070173872A1 (en) * 2006-01-23 2007-07-26 Ethicon Endo-Surgery, Inc. Surgical instrument for cutting and coagulating patient tissue
US20070191712A1 (en) * 2006-02-15 2007-08-16 Ethicon Endo-Surgery, Inc. Method for sealing a blood vessel, a medical system and a medical instrument
US7854735B2 (en) * 2006-02-16 2010-12-21 Ethicon Endo-Surgery, Inc. Energy-based medical treatment system and method
US7766937B2 (en) * 2006-03-13 2010-08-03 Mini-Lap Technologies, Inc. Minimally invasive surgical assembly and methods
US9282984B2 (en) 2006-04-05 2016-03-15 Flowcardia, Inc. Therapeutic ultrasound system
US7909033B2 (en) 2006-05-03 2011-03-22 Comedica Incorporated Breathing treatment apparatus
CA2652544A1 (en) 2006-05-18 2007-12-13 Breathe Technologies, Inc. Tracheostoma spacer, tracheotomy method, and device for inserting a tracheostoma spacer
US20080004596A1 (en) * 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
US8211052B1 (en) 2006-07-13 2012-07-03 Lexion Medical Llc Charged hydrator
US8663271B2 (en) 2006-08-04 2014-03-04 Northgate Technologies, Inc. In-dwelling port for access into a body
US8051854B2 (en) 2006-09-15 2011-11-08 Comedica Incorporated Continuous high-frequency oscillation breathing treatment apparatus
US20080230053A1 (en) * 2006-09-15 2008-09-25 Board Of Regents, The University Of Texas System Pulse drug nebulization systems, formulations therefore, and methods of use
US8012086B2 (en) * 2006-10-19 2011-09-06 Ethicon Endo-Surgery, Inc. Sterile transcolonic access device
US7993071B2 (en) 2006-10-25 2011-08-09 Burrell E. Clawson Assemblies for coupling two elements and coupled assemblies
US8246643B2 (en) 2006-11-07 2012-08-21 Flowcardia, Inc. Ultrasound catheter having improved distal end
NZ625605A (en) * 2006-11-08 2016-04-29 Resmed Ltd Conduit for use in a respiratory apparatus
US8991396B2 (en) * 2006-11-09 2015-03-31 The Board Of Trustees Of The University Of Illinois Endotracheal tube with two ports
US20100286791A1 (en) * 2006-11-21 2010-11-11 Goldsmith David S Integrated system for the ballistic and nonballistic infixion and retrieval of implants
US10350399B2 (en) 2006-11-27 2019-07-16 Frank Levy Apparatus and method for producing an enriched medical suspension of carbon dioxide
US11833320B2 (en) 2006-11-27 2023-12-05 Frank Levy Apparatus and process for producing CO2 enriched medical foam
US10322271B2 (en) 2006-11-27 2019-06-18 Frank Levy Delivery system and method for the effective and reliable delivery of controlled amounts of a medical fluid
US11185671B2 (en) 2006-11-27 2021-11-30 Frank Levy Apparatus and process for producing CO2 enriched medical foam
US20190070397A1 (en) * 2006-11-27 2019-03-07 Frank Levy Apparatus and method for producing co2 enriched medical foam
US20080132757A1 (en) * 2006-12-01 2008-06-05 General Electric Company System and Method for Performing Minimally Invasive Surgery Using a Multi-Channel Catheter
WO2008080153A2 (en) * 2006-12-22 2008-07-03 The Children's Hospital Of Philadelphia A novel protein kinase c therapy for the treatment of acute lung injury
US8491521B2 (en) * 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
WO2008091992A2 (en) * 2007-01-25 2008-07-31 C.R. Bard, Inc. Endotracheal and tracheostomy devices
JP2008199905A (en) * 2007-02-16 2008-09-04 Snow Brand Milk Prod Co Ltd Improving agent for survivability of lactic acid bacterium
DE202007003734U1 (en) * 2007-03-14 2008-07-17 Markus, Kai Ulf, Dr. Multi-lumen microcatheter
US8911460B2 (en) 2007-03-22 2014-12-16 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8057498B2 (en) 2007-11-30 2011-11-15 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instrument blades
US20080243050A1 (en) * 2007-03-28 2008-10-02 John Sylvester Power Insufflation of Body Cavities
US20090241948A1 (en) * 2007-03-28 2009-10-01 Dermot Joseph Clancy Humidification in breathing circuits
US8241266B2 (en) * 2007-04-05 2012-08-14 Entellus Medical, Inc. Apparatus and method for treatment of ethmoids
US20080269665A1 (en) * 2007-04-24 2008-10-30 Johan Petersen Chemotherapy delivery device
US20080283048A1 (en) * 2007-05-16 2008-11-20 Johan Petersen Two-stage reduction of aerosol droplet size
US9050434B2 (en) 2007-05-18 2015-06-09 Comedica Incorporated Lung therapy device
WO2008144589A1 (en) 2007-05-18 2008-11-27 Breathe Technologies, Inc. Methods and devices for sensing respiration and providing ventilation therapy
US8007470B2 (en) * 2007-07-10 2011-08-30 Cook Medical Technologies Llc Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall
US8808319B2 (en) 2007-07-27 2014-08-19 Ethicon Endo-Surgery, Inc. Surgical instruments
US8523889B2 (en) 2007-07-27 2013-09-03 Ethicon Endo-Surgery, Inc. Ultrasonic end effectors with increased active length
US8512365B2 (en) 2007-07-31 2013-08-20 Ethicon Endo-Surgery, Inc. Surgical instruments
US9044261B2 (en) 2007-07-31 2015-06-02 Ethicon Endo-Surgery, Inc. Temperature controlled ultrasonic surgical instruments
US8430898B2 (en) 2007-07-31 2013-04-30 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8215301B2 (en) 2007-08-29 2012-07-10 Smiths Medical Asd, Inc. Nose cannula heated/humidified gas delivery system
US8196579B2 (en) * 2007-08-29 2012-06-12 Smiths Medical Asd, Inc. Nose cannula heated/humidified gas delivery system
CN101873875B (en) 2007-09-26 2014-11-12 呼吸科技公司 Methods and devices for providing inspiratory and expiratory flow relief during ventilation therapy
CA2700869C (en) 2007-09-26 2018-10-30 Breathe Technologies, Inc. Methods and devices for treating sleep apnea
US20090088700A1 (en) * 2007-09-27 2009-04-02 Olympus Corporation Apparatus and method for liquid spray administration
MX2010003438A (en) * 2007-10-02 2010-04-21 Philip Morris Prod Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators.
US8052127B2 (en) 2007-10-19 2011-11-08 Philip Morris Usa Inc. Respiratory humidification system
US8597616B2 (en) 2007-10-22 2013-12-03 Board Of Regents Of The University Of Texas System Dry powder drug delivery formulations, methods of use, and devices therefore
JP5243548B2 (en) 2007-10-25 2013-07-24 プロテウス デジタル ヘルス， インコーポレイテッド Fluid communication port for information systems
US8419638B2 (en) 2007-11-19 2013-04-16 Proteus Digital Health, Inc. Body-associated fluid transport structure evaluation devices
JP5196672B2 (en) * 2007-11-29 2013-05-15 日本たばこ産業株式会社 Aerosol suction system
US10010339B2 (en) 2007-11-30 2018-07-03 Ethicon Llc Ultrasonic surgical blades
CA2712438C (en) 2008-01-25 2018-06-05 The Cleveland Clinic Foundation Methods and devices to clear obstructions from medical tubes
US8246752B2 (en) 2008-01-25 2012-08-21 Clear Catheter Systems, Inc. Methods and devices to clear obstructions from medical tubes
US20090212133A1 (en) * 2008-01-25 2009-08-27 Collins Jr James F Ophthalmic fluid delivery device and method of operation
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
US8770193B2 (en) 2008-04-18 2014-07-08 Breathe Technologies, Inc. Methods and devices for sensing respiration and controlling ventilator functions
WO2009151791A2 (en) 2008-04-18 2009-12-17 Breathe Technologies, Inc. Methods and devices for sensing respiration and controlling ventilator functions
US8251876B2 (en) 2008-04-22 2012-08-28 Hill-Rom Services, Inc. Breathing exercise apparatus
US9126025B2 (en) * 2008-05-01 2015-09-08 Bayer Intellectual Property Gmbh Method of coating a folded catheter balloon
CA2723183C (en) * 2008-05-06 2014-04-22 Richard W. Ducharme Apparatus and methods for delivering therapeutic agents
JP5178309B2 (en) * 2008-05-09 2013-04-10 オリンパス株式会社 Chemical solution administration device
US8088127B2 (en) 2008-05-09 2012-01-03 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
US9775632B2 (en) * 2008-05-23 2017-10-03 Medinol Ltd. Method and device for recanalization of total occlusions
US8690839B2 (en) 2008-08-01 2014-04-08 Tian Xia Devices for delivering a medicament and connector for same
US8231588B2 (en) 2008-08-01 2012-07-31 Tian Xia Methods for ameliorating pain and devices for delivering a medicament
US8905980B2 (en) 2008-08-01 2014-12-09 Tian Xia Devices for delivering a medicament and methods for ameliorating pain
CN102196837B (en) 2008-08-22 2015-09-09 呼吸科技公司 Open air flue interface is utilized to provide the method and apparatus of mechanical ventilation
US10478125B2 (en) * 2008-09-09 2019-11-19 Pulmonx Corporation Systems and methods for flushing an assessment catheter
WO2010039989A1 (en) 2008-10-01 2010-04-08 Breathe Technologies, Inc. Ventilator with biofeedback monitoring and control for improving patient activity and health
EP2189171A1 (en) * 2008-11-25 2010-05-26 Covidien AG Mobile chest drainage unit, thoracic catheter, system comprising a mobile chest drainage unit and a thoracic catheter, and manufacturing method thereof
JP5631332B2 (en) * 2008-12-23 2014-11-26 クック メディカル テクノロジーズ エルエルシーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ Apparatus and method for containing and delivering therapeutic agents
US9132250B2 (en) 2009-09-03 2015-09-15 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with an entrainment port and/or pressure feature
US9227034B2 (en) 2009-04-02 2016-01-05 Beathe Technologies, Inc. Methods, systems and devices for non-invasive open ventilation for treating airway obstructions
US8468637B2 (en) 2009-02-06 2013-06-25 Endoclear Llc Mechanically-actuated endotracheal tube cleaning device
EP2393538B1 (en) 2009-02-06 2017-10-18 Endoclear LLC Devices for cleaning endotracheal tubes
WO2011126812A1 (en) 2010-03-29 2011-10-13 Endoclear, Llc Airway cleaning and visualization
JP5603559B2 (en) * 2009-03-17 2014-10-08 オリンパス株式会社 Chemical spray device
US9962512B2 (en) 2009-04-02 2018-05-08 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with a free space nozzle feature
US8226566B2 (en) 2009-06-12 2012-07-24 Flowcardia, Inc. Device and method for vascular re-entry
EP2442861B1 (en) 2009-06-19 2019-01-02 BrainCool AB Devices for cooling the nasal cavity
US8344596B2 (en) 2009-06-24 2013-01-01 Ethicon Endo-Surgery, Inc. Transducer arrangements for ultrasonic surgical instruments
US20110030680A1 (en) * 2009-07-30 2011-02-10 Nellcor Puritan Bennett Llc Tracheal tube with drug delivery device and method of using the same
CA2774902C (en) 2009-09-03 2017-01-03 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with an entrainment port and/or pressure feature
US8567401B2 (en) 2009-09-18 2013-10-29 Kimberly Clark Worldwide, Inc. Looped tether for medical ventilating and aspirating devices
US10058675B2 (en) 2009-09-21 2018-08-28 Cook Regentec Llc Infusion catheter tip for biologics with reinforced external balloon valve
US10155099B2 (en) 2009-09-21 2018-12-18 Cook Regentec Llc Method for infusing stem cells
CN104042322B (en) 2009-10-27 2017-06-06 赫莱拉公司 Delivery apparatus with coolable energy transmitting device
US20110100360A1 (en) * 2009-11-02 2011-05-05 Joseph Dee Faram Composite lung therapy device and method
US9151425B2 (en) 2009-11-02 2015-10-06 Comedica Incorporated Multiple conduit connector apparatus and method
AU2010319477A1 (en) 2009-11-11 2012-05-24 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
US8398579B2 (en) 2009-12-16 2013-03-19 Medrad, Inc. Catheter including composite guide and methods for use of the same
US9132064B2 (en) * 2009-12-23 2015-09-15 Avent, Inc. Enteral feeding catheter assembly incorporating an indicator
US9326757B2 (en) 2009-12-31 2016-05-03 Teleflex Medical Incorporated Surgical instruments for laparoscopic aspiration and retraction
SG189763A1 (en) 2010-02-01 2013-05-31 Proteus Digital Health Inc Two-wrist data gathering system
SG182825A1 (en) 2010-02-01 2012-09-27 Proteus Biomedical Inc Data gathering system
US8486096B2 (en) 2010-02-11 2013-07-16 Ethicon Endo-Surgery, Inc. Dual purpose surgical instrument for cutting and coagulating tissue
US8951272B2 (en) 2010-02-11 2015-02-10 Ethicon Endo-Surgery, Inc. Seal arrangements for ultrasonically powered surgical instruments
US8974771B2 (en) * 2010-03-09 2015-03-10 Penn-Century, Inc. Apparatus and method for aerosol delivery to the lungs or other locations of the body
WO2011130639A1 (en) 2010-04-15 2011-10-20 Entellus Medical, Inc. Method and apparatus for treating dilating the ethmoid infundibulum
JP2011239957A (en) * 2010-05-18 2011-12-01 Tokyo Univ Of Science Pulmonary drug administration instrument, and pulmonary drug administration device
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
EA201390120A3 (en) 2010-07-15 2013-09-30 Коринтиан Офтэлмик, Инк. DELIVERY OF OPHTHALMIC MEDICINES
EP2593055A1 (en) 2010-07-15 2013-05-22 Corinthian Ophthalmic, Inc. Method and system for performing remote treatment and monitoring
BR112013001030B8 (en) 2010-07-15 2021-05-11 Corinthian Ophthalmic Inc droplet generating device for use in delivering a volume of ophthalmic fluid to a subject's eye
EP2605836A4 (en) 2010-08-16 2016-06-01 Breathe Technologies Inc Methods, systems and devices using lox to provide ventilatory support
CA3011128C (en) 2010-08-24 2019-11-19 Trudell Medical International Aerosol delivery device
CA2811423C (en) 2010-09-30 2019-03-12 Breathe Technologies, Inc. Methods, systems and devices for humidifying a respiratory tract
JP2013540040A (en) * 2010-10-20 2013-10-31 ウルフ トリー メディカル インコーポレイテッド Small fluid sprayer
US8177742B1 (en) * 2010-12-23 2012-05-15 Kimberly-Clark Wordwide, Inc. Inflatable retention system for an enteral feeding device
GB201119794D0 (en) 2011-11-16 2011-12-28 Airway Medix Spolka Z O O Ballooned ventilation tube cleaning device
US8631798B2 (en) * 2011-03-29 2014-01-21 Carefusion 207, Inc. Valving a respiratory gas pathway with a catheter balloon
WO2012131626A2 (en) * 2011-03-29 2012-10-04 Airway Medix Spolka Z.O.O. Ballooned ventilation tube cleaning device
US20120259244A1 (en) * 2011-04-08 2012-10-11 Salient Surgical Technologies, Inc. Catheter Systems and Methods of Use
EP2707146B1 (en) 2011-05-09 2021-04-28 Impel NeuroPharma Inc. Nozzles for nasal drug delivery
US20120316589A1 (en) * 2011-06-07 2012-12-13 Cook Medical Technologies Llc Balloon catheter with raised elements and visual marker
WO2013016056A2 (en) * 2011-07-25 2013-01-31 Acclarent, Inc. Devices and methods for transnasal dilation and irrigation of the sinuses
US9095364B2 (en) * 2011-07-28 2015-08-04 Acclarent, Inc. Device and method for dilating an airway stenosis
WO2013063520A1 (en) 2011-10-27 2013-05-02 Endoclear, Llc Endotracheal tube coupling adapters
TWM423561U (en) * 2011-10-27 2012-03-01 Changhua Christian Hospital Isolation device capable of replacing sputum suction tube
US10441959B2 (en) * 2011-10-28 2019-10-15 Medtronic Xomed, Inc. Multi-orifice spray head
EP2790619A1 (en) 2011-12-12 2014-10-22 Corinthian Ophthalmic, Inc. Ejector mechanism, ejector device, and methods of use
CA2857320C (en) 2012-01-18 2020-08-11 Bard Peripheral Vascular, Inc. Vascular re-entry device
EP2806931B1 (en) 2012-01-23 2019-04-10 AEON Research and Technology, LLC Modular pulmonary treatment system
US9282772B2 (en) * 2012-01-31 2016-03-15 Altria Client Services Llc Electronic vaping device
KR20140135197A (en) * 2012-02-16 2014-11-25 카프니아, 인코포레이티드 Gas dispenser with diffusing nosepiece
US9180271B2 (en) 2012-03-05 2015-11-10 Hill-Rom Services Pte. Ltd. Respiratory therapy device having standard and oscillatory PEP with nebulizer
JP6104513B2 (en) * 2012-03-09 2017-03-29 エア・ウォーター株式会社 Ventilator
WO2013160129A1 (en) * 2012-04-23 2013-10-31 Chiesi Farmaceutici S.P.A. Method and system for the administration of a pulmonary surfactant by atomization
WO2013165473A1 (en) * 2012-05-01 2013-11-07 Therox, Inc. System and method for bubble-free gas-enrichment of flowing liquid within a conduit
SG11201407429PA (en) * 2012-05-17 2014-12-30 Translational Biolog Infusion Catheter Llc Infusion catheter tip for biologics
US20130318922A1 (en) * 2012-05-30 2013-12-05 Nosocomial Containment Products Inc. Cannula holders
US10518056B2 (en) 2012-05-30 2019-12-31 Infection Prevention Products, Inc. Cannula holders
US9820768B2 (en) 2012-06-29 2017-11-21 Ethicon Llc Ultrasonic surgical instruments with control mechanisms
JP6312262B2 (en) * 2012-07-12 2018-04-18 マンカインド コーポレイション Dry powder drug delivery system
EP2879596A2 (en) 2012-08-02 2015-06-10 Flowcardia, Inc. Ultrasound catheter system
US9833207B2 (en) 2012-08-08 2017-12-05 William Harrison Zurn Analysis and clearing module, system and method
US9174001B2 (en) 2012-08-10 2015-11-03 Nordson Corporation Device and method for discharging a reactive liquid
US9713687B2 (en) 2012-08-21 2017-07-25 Philip Morris Usa Inc. Ventilator aerosol delivery system with transition adapter for introducing carrier gas
WO2014055675A1 (en) * 2012-10-02 2014-04-10 Lutz Freitag Devices and methods for pulmonary diagnosis
US11013876B2 (en) 2012-11-12 2021-05-25 Inovytec Medical Solutions Ltd. System and method for providing ventilation
IL223004A (en) * 2012-11-12 2017-01-31 Inovytec Medical Solutions Ltd System for providing non-invasive ventilation
US9795752B2 (en) 2012-12-03 2017-10-24 Mhs Care-Innovation, Llc Combination respiratory therapy device, system, and method
US12080401B2 (en) 2012-12-03 2024-09-03 Metrohealth Ventures Llc Combination respiratory therapy device, system and method
US10004863B2 (en) 2012-12-04 2018-06-26 Endoclear Llc Closed suction cleaning devices, systems and methods
WO2014089519A1 (en) 2012-12-07 2014-06-12 Bartlett Ii Rush L System for reducing local discomfort
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9962533B2 (en) 2013-02-14 2018-05-08 William Harrison Zurn Module for treatment of medical conditions; system for making module and methods of making module
US10226273B2 (en) 2013-03-14 2019-03-12 Ethicon Llc Mechanical fasteners for use with surgical energy devices
US20140261407A1 (en) 2013-03-14 2014-09-18 Patient Centered Medical Incorporated Aspiration catheters, systems, and methods
US11103684B2 (en) 2013-03-15 2021-08-31 Nuvaira, Inc. Systems, devices, and methods for treating a pulmonary disorder with an agent
US11759186B2 (en) * 2018-06-08 2023-09-19 David S. Goldsmith Ductus side-entry and prosthetic disorder response systems
US10828446B2 (en) 2013-09-12 2020-11-10 Mayo Foundation For Medical Education And Research Insulated endotracheal devices and systems for transpulmonary thermal transfer
CN105579090A (en) 2013-09-23 2016-05-11 那伽巡线导管有限公司 Endotracheal tube and method of use
TW201609206A (en) * 2013-10-22 2016-03-16 奇希製藥公司 Improved method and system for the administration of a pulmonary surfactant by atomization
US10034986B2 (en) * 2013-11-11 2018-07-31 Crossbay Medical, Inc. Method and apparatus of tubal patency catheter and delivery systems
US9028401B1 (en) 2013-11-11 2015-05-12 Cross Bay Medical, Inc. Apparatus and methods for accessing and sealing bodily vessels and cavities
US10245074B2 (en) 2013-11-11 2019-04-02 Crossbay Medical, Inc. Apparatus and methods for accessing and sealing bodily vessels and cavities
US11224767B2 (en) 2013-11-26 2022-01-18 Sanuwave Health, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
GB2521229A (en) 2013-12-16 2015-06-17 Ethicon Endo Surgery Inc Medical device
US20150224279A1 (en) * 2014-02-11 2015-08-13 Kenneth G. Miller Medical Aerosol Device
US10471189B2 (en) 2014-02-17 2019-11-12 Clearflow, Inc. Medical tube clearance device
CN116920264A (en) 2014-02-17 2023-10-24 科里福罗公司 Medical tube cleaning
US9572595B1 (en) 2014-03-05 2017-02-21 Northgate Technologies Inc. In-dwelling port for access into a body
US10456536B2 (en) 2014-03-25 2019-10-29 Koninklijke Philips N.V. Inhaler with two microphones for detection of inhalation flow
GB201408561D0 (en) * 2014-05-14 2014-06-25 The Technology Partnership Plc Aerosolisation engine for liquid drug delivery
WO2015179300A1 (en) 2014-05-18 2015-11-26 Awair, Inc. Device to reduce discomfort in the upper airway
US10016575B2 (en) 2014-06-03 2018-07-10 Endoclear Llc Cleaning devices, systems and methods
US10500360B1 (en) 2014-08-29 2019-12-10 Teleflex Life Sciences Unlimited Company Catheter for cleaning of tracheal ventilation tubes
US10398875B2 (en) 2015-01-09 2019-09-03 Accurate Medical Therapeutics Ltd. Embolization microcatheter
US20210236758A1 (en) * 2015-01-13 2021-08-05 Trudell Medical International Respiratory interface
JP6839086B2 (en) 2015-01-13 2021-03-03 トゥルーデル メディカル インターナショナル Respiratory interface
ITMI20150033U1 (en) * 2015-02-13 2016-08-13 Chiesi Farm Spa CATHETER FOR THE ADMINISTRATION OF A PULMONARY SURFACTANT
WO2016139590A1 (en) 2015-03-02 2016-09-09 Accurate Medical Therapeutics Ltd. Embolization particulates for occluding a blood vessel
EP4186548A1 (en) 2015-04-02 2023-05-31 Hill-Rom Services PTE. LTD. Mask leakage detection for a respiratory device
EP3106090A1 (en) * 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
US11219730B2 (en) * 2015-04-28 2022-01-11 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
PT108426B (en) * 2015-04-30 2017-07-24 Hovione Farmaciência S A POWDER INHALER FOR ADMINISTRATION OF HIGH DOSES OF DRUGS
US11020140B2 (en) 2015-06-17 2021-06-01 Cilag Gmbh International Ultrasonic surgical blade for use with ultrasonic surgical instruments
US10357303B2 (en) 2015-06-30 2019-07-23 Ethicon Llc Translatable outer tube for sealing using shielded lap chole dissector
EP3718590B1 (en) * 2015-07-13 2023-06-21 Cook Regentec LLC Catheters and systems useful for delivery of material to the lung
USD800981S1 (en) * 2015-10-01 2017-10-24 Foamtec International Co., Ltd. Cleaning device with tail swab
US10537462B1 (en) * 2015-11-06 2020-01-21 Wildhatch, LLC Colostomy appliance with flushable insert
GB2546082B (en) 2016-01-06 2018-05-16 Airway Medix S A Closed suction system
US11452831B2 (en) 2016-01-06 2022-09-27 Airway Medix S.A. Closed suction system
WO2017151918A1 (en) * 2016-03-02 2017-09-08 Cross Bay Medical, Inc. Method and apparatus of echogenic catheter systems
US11129960B2 (en) 2016-05-04 2021-09-28 Accurate Medical Therapeutics Ltd. Embolization microcatheter head having slitted pattern
US10946153B2 (en) 2016-05-16 2021-03-16 Teleflex Life Sciences Pte. Ltd. Mechanical user control elements for fluid input module
US10245064B2 (en) 2016-07-12 2019-04-02 Ethicon Llc Ultrasonic surgical instrument with piezoelectric central lumen transducer
MA45772A (en) 2016-07-28 2021-04-28 Chiesi Farm Spa METHOD AND SYSTEM FOR ADMINISTRATION OF A MEDICINAL IN THE FORM OF AEROSOL
RU2649500C2 (en) * 2016-08-01 2018-04-03 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Device and method for evaluating the intravital tone of trachea and bronchus wall
USD847990S1 (en) 2016-08-16 2019-05-07 Ethicon Llc Surgical instrument
US10828056B2 (en) 2016-08-25 2020-11-10 Ethicon Llc Ultrasonic transducer to waveguide acoustic coupling, connections, and configurations
US10952759B2 (en) 2016-08-25 2021-03-23 Ethicon Llc Tissue loading of a surgical instrument
JP2017140359A (en) * 2016-10-26 2017-08-17 ウルフ トリー メディカル インコーポレイテッド Miniature fluid atomizer
CN109890446B (en) * 2016-10-26 2022-03-22 奇斯药制品公司 Device for assisting in the delivery of a medicament to the lungs through a catheter
EP3537997A4 (en) 2016-11-14 2020-09-23 Gynion, LLC System and method for delivering therapeutic agents to the uterine cavity
BR112019006390A2 (en) * 2016-11-23 2019-06-25 Hoffmann La Roche reservoir for storing a liquid medicine, method for producing a reservoir, method for filling a reservoir, method for delivering a liquid medicine and medical pump for administration ”
US20180140321A1 (en) 2016-11-23 2018-05-24 C. R. Bard, Inc. Catheter With Retractable Sheath And Methods Thereof
US11596726B2 (en) 2016-12-17 2023-03-07 C.R. Bard, Inc. Ultrasound devices for removing clots from catheters and related methods
US10758256B2 (en) 2016-12-22 2020-09-01 C. R. Bard, Inc. Ultrasonic endovascular catheter
US10582983B2 (en) 2017-02-06 2020-03-10 C. R. Bard, Inc. Ultrasonic endovascular catheter with a controllable sheath
RU187720U1 (en) * 2017-02-27 2019-03-15 Владимир Михайлович Шавяк AEROSOL PROBE FOR DELIVERY OF EXTINGUISHING AND OTHER SUBSTANCES
RU2732379C1 (en) 2017-03-20 2020-09-16 Вектура Деливери Дивайсиз Лимитед Method and container for cleaning nebuliser membrane
WO2018172293A1 (en) * 2017-03-20 2018-09-27 Vectura Delivery Devices Limited Container for cleaning the membrane of a nebulizer
CN115300226A (en) 2017-06-10 2022-11-08 艾诺维亚股份有限公司 Apparatus for delivering a volume of fluid to an eye
DE102017006185A1 (en) * 2017-06-30 2019-01-03 CAPNOMED GmbH Device for the directed introduction of a substance into a cavity
AU2018297680B2 (en) * 2017-07-05 2021-04-01 Airway Medix S.A. Mechanical user control elements for fluid input module
US20190038791A1 (en) * 2017-08-02 2019-02-07 Sanovas Intellectual Property, Llc Medical Device Inspection and Sterilization
US10792449B2 (en) 2017-10-03 2020-10-06 Breathe Technologies, Inc. Patient interface with integrated jet pump
RU189311U1 (en) * 2017-10-30 2019-05-21 Ринокер Лтд Device for preparing a controlled mixture for high temperature procedures
BR112020008852A2 (en) 2017-11-02 2020-10-20 Accurate Medical Therapeutics Ltd. embolization catheter with integrated filter
RU179824U1 (en) * 2017-12-27 2018-05-24 федеральное государственное бюджетное образовательное учреждение высшего образования "Омский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОмГМУ Минздрава России) Ultrasonic oro-epipharengeal waveguide atomizer
CN111801131A (en) * 2018-01-11 2020-10-20 由退伍军人事务部代表的美国政府 Sampling catheter with articulating tip
US11185643B2 (en) * 2018-04-06 2021-11-30 Frank Levy Apparatus and method for producing an enriched medical suspension
JP2019005589A (en) * 2018-07-19 2019-01-17 ウルフ トリー メディカル インコーポレイテッド Miniature fluid atomizer
US10576248B2 (en) 2018-07-23 2020-03-03 Crossbay Medical, Inc. Apparatus and method for everting catheter for uterine access for biopsy and cytology
US20210330908A1 (en) * 2018-09-05 2021-10-28 Vikare, Llc Negative air pressure devices and uses thereof
EP3856318A4 (en) * 2018-09-28 2022-06-15 Flow Medical Corporation Catheter apparatus
EP3666320A1 (en) * 2018-12-10 2020-06-17 Brussels Medical Device Center ASBL Catheter for delivering an agent
CN109700507A (en) * 2018-12-28 2019-05-03 先健科技(深圳)有限公司 Sting device
US11406786B2 (en) 2019-04-22 2022-08-09 Sunovion Pharmaceuticals Inc. Nebulizer monitoring device, system and method
NL2023355B1 (en) * 2019-06-21 2021-02-01 Stichting Katholieke Univ Oropharyngeal airway device
CN114828761A (en) 2019-10-09 2022-07-29 克劳斯贝医疗有限公司 Apparatus and method for delivering and placing an everting catheter for an IUD in the uterine cavity
US12070554B2 (en) 2019-11-11 2024-08-27 Hill-Rom Services Pte. Ltd. Pneumatic connector apparatus and method
GB202006151D0 (en) * 2020-04-27 2020-06-10 Smiths Medical International Ltd Reinforced medico-surgical tubes anbd their manufacture
EP3932457A1 (en) * 2020-07-02 2022-01-05 Carag AG Tracheal catheter, intubation hose and treatment device
CN111632245B (en) * 2020-05-06 2022-01-04 上海交通大学医学院附属第九人民医院 Trachea cannula capable of implementing throat soothing anesthesia
KR102511585B1 (en) * 2020-11-08 2023-03-16 부산대학교 산학협력단 Talc spray module of catheter for fiber glue application under pleurography
JP2023549541A (en) 2020-11-17 2023-11-27 クリアフロー， インコーポレイテッド Medical tube cleaning device
EP4277685A1 (en) * 2021-01-18 2023-11-22 Gynion, LLC System and method for delivering therapeutic agents to the uterine cavity
KR102563113B1 (en) * 2021-01-29 2023-08-02 인제대학교 산학협력단 Endotracheal intubation tube
US20240307656A1 (en) * 2021-02-19 2024-09-19 Zoll Circulation, Inc. Catheters and systems for direct injection of gas-enriched liquid into a patient
US20220273898A1 (en) * 2021-02-28 2022-09-01 Maurizio Radicioni Assembly for tracheal instillation of fluid medicaments in infants supported by non-invasive ventilation
WO2023287963A1 (en) * 2021-07-14 2023-01-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Endotracheal tubes with baffles
US11963665B2 (en) * 2021-10-27 2024-04-23 Olympus Medical Systems Corp. Endoscope and endoscope system
GB202201107D0 (en) 2022-01-28 2022-03-16 Kindeva Drug Delivery Lp Device for delivery of a compound to specific regions of the nasal cavity
DE102022104560A1 (en) * 2022-02-25 2023-08-31 Capnopharm UG (haftungsbeschränkt) Medical instrument for introducing a fluid therapeutic substance into a body cavity

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US606240A (en) * 1898-06-28 Atomizer
US790318A (en) * 1904-01-25 1905-05-23 Walter Sams Atomizer.
US817819A (en) * 1905-08-18 1906-04-17 Liberty Walkup Air-brush.
US829952A (en) * 1905-10-14 1906-09-04 Walter M Dean Syringe.
US852154A (en) * 1906-01-16 1907-04-30 Martin Bariffi Syringe.
US970576A (en) * 1910-06-24 1910-09-20 Martha Von Trautmann Atomizer.
US1990824A (en) * 1934-04-16 1935-02-12 Binks Mfg Co Air nozzle for flat-spraying appliances
US2029423A (en) * 1935-02-28 1936-02-04 Binks Mfg Co Air nozzle for flat spraying appliances
US2070695A (en) * 1935-12-09 1937-02-16 Vilbiss Co Spray head
US2070696A (en) * 1935-12-11 1937-02-16 Vilbiss Co Spray head
US2204599A (en) * 1936-01-09 1940-06-18 Jenkins Alexander Frederick Spray gun
US2235708A (en) * 1938-01-10 1941-03-18 Alexander F Jenkins Spraying device
US2271779A (en) * 1941-05-15 1942-02-03 Vilbiss Co Spray nozzle
US2633908A (en) * 1947-01-24 1953-04-07 Ralph C Brierly Diffuser
US2638096A (en) 1949-11-08 1953-05-12 Edith A Waldhaus Apparatus for oral anesthesia
US2646314A (en) * 1950-10-19 1953-07-21 Vilbiss Co Spray nozzle
US2942790A (en) * 1959-01-23 1960-06-28 Gen Electric Air-atomizing liquid spray nozzle
US3306289A (en) * 1962-01-02 1967-02-28 Mist O2 Gen Equipment Co Oxygen tent atmosphere conditioning apparatus and method
US3269389A (en) * 1963-03-11 1966-08-30 Bernard L Meurer Compartmental dispensing container for nose and throat preparations
US3370112A (en) * 1963-09-26 1968-02-20 Raychem Corp Process and apparatus for producing plastic memory articles
US3561444A (en) * 1968-05-22 1971-02-09 Bio Logics Inc Ultrasonic drug nebulizer
US3634924A (en) * 1970-04-20 1972-01-18 American Hospital Supply Corp Method of making multilumen balloon catheter
US3788326A (en) 1970-07-29 1974-01-29 H Jacobs Distally perforated catheter for use in ventilating system
US3812854A (en) * 1972-10-20 1974-05-28 A Michaels Ultrasonic nebulizer
US4327721A (en) 1978-07-07 1982-05-04 George Hanover Endotracheal tube with topical agent delivery system and method of using the same
DE2831313A1 (en) * 1978-07-17 1980-02-07 Draegerwerk Ag DEVICE FOR SUPPORTING BREATHING AND / OR ARTIFICIAL VENTILATION
DE2847681C2 (en) * 1978-11-03 1983-01-05 Drägerwerk AG, 2400 Lübeck Tracheal tube
US4273293A (en) * 1978-12-20 1981-06-16 Nordson Corporation Nozzle assembly for electrostatic spray guns
JPS5848225B2 (en) * 1979-01-09 1983-10-27 オムロン株式会社 Atomization amount control method of ultrasonic liquid atomization device
CH627108A5 (en) 1979-03-09 1981-12-31 Charmilles Sa Ateliers
US4495946A (en) * 1981-03-17 1985-01-29 Joseph Lemer Artificial breathing device
US4662404A (en) * 1981-05-15 1987-05-05 Leveen Harry H Flexible tubing
DE3119814C2 (en) * 1981-05-19 1984-07-26 Drägerwerk AG, 2400 Lübeck HFJ ventilator with a controllable breathing gas source and device for generating negative pressure
DE3119854A1 (en) 1981-05-19 1982-12-16 Drägerwerk AG, 2400 Lübeck DEVICE FOR POSITIONING A TRACHEAL TUBE
US5116088A (en) 1981-08-10 1992-05-26 Bird F M Ventilator having an oscillatory inspiratory phase and method
US4584998A (en) * 1981-09-11 1986-04-29 Mallinckrodt, Inc. Multi-purpose tracheal tube
DE3212097C2 (en) * 1982-04-01 1985-10-03 Drägerwerk AG, 2400 Lübeck Ventilator with a breathing gas source that can be controlled via a control unit
US4567882A (en) * 1982-12-06 1986-02-04 Vanderbilt University Method for locating the illuminated tip of an endotracheal tube
US4502482A (en) * 1983-05-23 1985-03-05 Deluccia Victor C Endotracheal tube complex
US4580371A (en) * 1983-10-17 1986-04-08 Iolab Corporation Method for tumble grinding optical lens edge
US4669463A (en) * 1984-02-22 1987-06-02 Mcconnell Richard B Endotracheal tube injection site addition
US5277177A (en) * 1984-07-23 1994-01-11 Ballard Medical Products Single use medical aspirating device and method
FR2569114B1 (en) * 1984-08-20 1988-11-18 Biotrol Sa Lab HIGH-THROUGHPUT INJECTION PROBE FOR CONTRAST PRODUCT FOR RADIOLOGICAL EXAMINATIONS AND METHOD FOR OBTAINING SAME
DE3435849C2 (en) 1984-09-29 1987-04-16 Paul Peter Prof. Dr.med. 4400 Münster Lunkenheimer Air pulse generators in ventilators
DE3583141D1 (en) * 1984-11-15 1991-07-11 Stefano Nazari DEVICE FOR SELECTIVE BRONCHIAL INTUBATION AND SEPARATE LUNG VENTILATION.
CS252710B1 (en) * 1984-12-28 1987-10-15 Ondrej Brychta Multi-jet generator for high-frequency jet lung-ventilation
US4661110A (en) * 1985-05-13 1987-04-28 Sherwood Medical Company Multiple passage connector fitting for a medical tube
US4655746A (en) * 1985-12-02 1987-04-07 Target Therapeutics Catheter device
US4735620A (en) * 1986-01-16 1988-04-05 Ruiz Oscar F Non-whip catheter
GB8604328D0 (en) * 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
DE8607358U1 (en) 1986-03-18 1986-05-28 Ruß, Jürgen, 5300 Bonn Tubular, flexible probe for insertion into the trachea and bronchi
GB8614805D0 (en) * 1986-06-18 1986-07-23 British American Tobacco Co Aerosol device
US4840172A (en) * 1986-09-04 1989-06-20 Augustine Scott D Device for positioning an endotracheal tube
DE3636669C2 (en) * 1986-10-28 2001-08-16 Siemens Ag Arrangement for delivering aerosol to a patient's airways and / or lungs
US4821714A (en) * 1986-12-04 1989-04-18 Smelser Danny N Pharmaceutical endotracheal tube
US4739756A (en) * 1986-12-19 1988-04-26 Horn Sherman W Endotracheal tube
JP2656944B2 (en) * 1987-04-30 1997-09-24 クーパー ラボラトリーズ Aerosolization of protein therapeutics
US4832012A (en) * 1987-07-08 1989-05-23 Vortran Medical Technology, Inc. Intermittent signal actuated nebulizer
US4805609A (en) 1987-07-17 1989-02-21 Josephine A. Roberts Pressurized ventilation system for patients
US5119807A (en) 1987-07-17 1992-06-09 Josephine A. Roberts Pressurized medical ventilation system
EP0369012A4 (en) 1987-07-23 1990-12-27 Terumo Kabushiki Kaisha Catheter tube
US5072726A (en) 1987-10-09 1991-12-17 University Of Pittsburgh Of The Commonwealth System Of Higher Education Vaporizer for inhalation anesthetics during high-frequency jet ventilation and associated method
US4886055A (en) 1988-01-22 1989-12-12 Hoppough John M Nebulizer device
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device
US4955375A (en) * 1989-01-23 1990-09-11 Ricardo Martinez Endotracheal tube with channel for delivering drugs
US5012804A (en) 1989-03-06 1991-05-07 Trudell Medical Medication inhaler with adult mask
US5031613A (en) * 1989-06-07 1991-07-16 JoAnne Hahn Nebulizing catheter
AU650845B2 (en) * 1989-08-28 1994-07-07 K. Michael Sekins Lung cancer hyperthermia via ultrasound and/or convection with perfluorocarbon liquids
US5049137A (en) * 1989-09-08 1991-09-17 Thompson Jeffrey E Prepackaged syringe and catheter apparatus for deep administration of a fluid, and method of making same
US5515844A (en) * 1989-11-02 1996-05-14 Christopher; Kent L. Method and apparatus for weaning ventilator-dependent patients
US5207220A (en) * 1989-12-12 1993-05-04 Burroughs Wellcome Co. Method for administering pharmaceuticals, including liquid surfactant, to the lungs
US5231983A (en) * 1990-01-03 1993-08-03 Minnesota Mining And Manufacturing Method of and apparatus for the aerosol administration of medication
US5146916A (en) * 1990-01-05 1992-09-15 Catalani Angelo S Endotracheal tube incorporating a drug-irrigation device
US5062423A (en) * 1990-02-27 1991-11-05 Minnesota Mining And Manufacturing Company Equine aerosol drug delivery method and apparatus
US4990133A (en) * 1990-04-02 1991-02-05 Tenax-Glynn Corporation Removable J-J ureteral stent
US5125893A (en) * 1990-04-16 1992-06-30 Dryden Gale E Suction catheter with wall lumen for irrigation
US5025806A (en) * 1990-04-16 1991-06-25 Ballard Medical Products Medical ventilating and a spirating apparatus and methods
US5106368A (en) 1990-04-20 1992-04-21 Cook Incorporated Collapsible lumen catheter for extracorporeal treatment
US5078131A (en) 1990-05-21 1992-01-07 Trudell Medical Introduction of medication in ventilator circuit
US5193533A (en) * 1990-07-09 1993-03-16 Brigham And Women's Hospital High-pressure jet ventilation catheter
US5029580A (en) 1990-07-18 1991-07-09 Ballard Medical Products Medical aspirating apparatus with multi-lumen catheter tube and methods
US5261892A (en) 1990-07-25 1993-11-16 Abbott Laboratories Sensor delivery device
US5060646A (en) * 1990-09-10 1991-10-29
US5178138A (en) 1990-09-11 1993-01-12 Walstrom Dennis R Drug delivery device
US5233979A (en) * 1990-10-22 1993-08-10 Ballard Medical Products Methods and apparatus for a micro-tracheal catheter hub assembly
CA2054455A1 (en) 1990-11-23 1992-05-24 John James Delany Substituted-2,3-dihydro-2-oxo-1,5-benzodiazepines and their use as fungicides
US5167622A (en) * 1990-12-07 1992-12-01 Smiths Industries Medical Systems, Inc. Triple conduit suction catheter
US5285778A (en) * 1991-04-19 1994-02-15 Mackin Robert A Endotracheal tube wih fibers optic illumination and viewing and auxiliary tube
US5287850A (en) 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
US5313939A (en) 1991-10-11 1994-05-24 University Of Pittsburgh Of The Commonwealth System Of Higher Education Endotracheal™ tube for topical substance delivery and associated method of use
US5217005A (en) * 1991-11-01 1993-06-08 Weinstein James D Apparatus for performing percutaneous tracheostomies and cricothyroidectomies
US5197463A (en) * 1991-12-10 1993-03-30 Jeshuran Winston R Single stage seal adaptor for endotracheal intubation and removal of anesthesia mask
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
ATE192048T1 (en) * 1992-03-10 2000-05-15 Univ Duke ENDOTRACHEAL TUBE WITH AEROSOL GENERATING DEVICE
US5318517A (en) * 1992-03-30 1994-06-07 Reiman James A Multiple lumen thoracostomy catheter and method for administering anesthesia
US5333607A (en) 1992-10-19 1994-08-02 Sherwood Medical Company Ventilator manifold with accessory access port
US5372131A (en) 1992-04-28 1994-12-13 Heinen, Jr.; Leo F. Triangular intratracheal tube
GB9209779D0 (en) * 1992-05-06 1992-06-17 Caswell Simon J Intermittent external pulse pump
US5291882A (en) * 1992-05-11 1994-03-08 Makhoul Imad R Multi-lumen ITPV endotracheal tube
DE4221931C1 (en) * 1992-07-03 1993-07-08 Harald Dr. 8521 Moehrendorf De Mang
US5287849A (en) * 1992-07-24 1994-02-22 Vortran Medical Technology, Inc. Medicinal aerosol delivery system and method of use
US5287847A (en) 1992-07-24 1994-02-22 Vortran Medical Technology, Inc. Universal nebulizer
GB2273660B (en) * 1992-09-11 1996-07-17 Aid Medic Ltd Drug delivery arrangement
US5443447A (en) * 1992-09-24 1995-08-22 Amin I. Kassis Intracavitary delivery or withdrawal device
US5477860A (en) * 1992-11-05 1995-12-26 Synectics Medical, Inc. Catheter for measuring respiration and respiratory effort
US5329921A (en) * 1993-03-01 1994-07-19 Spiro Socaris Endotracheal tube
US5546935A (en) * 1993-03-09 1996-08-20 Medamicus, Inc. Endotracheal tube mounted pressure transducer
JP3635090B2 (en) * 1993-03-16 2005-03-30 ヴァス−カス インコーポレイテッド Catheter and method for manufacturing the same
US5433195A (en) 1993-09-30 1995-07-18 Sherwood Medical Company Respiratory support system
US5499625A (en) 1994-01-27 1996-03-19 The Kendall Company Esophageal-tracheal double lumen airway
EP0758257B1 (en) * 1994-05-06 2000-02-23 Mark Brauner Apparatus for intrapulmonary therapy and drug administration
US5803078A (en) 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
US5642730A (en) * 1994-06-17 1997-07-01 Trudell Medical Limited Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister
ZA954936B (en) * 1994-06-17 1996-02-27 Trudell Medical Ltd Nebulizing catheter system and methods of use and manufacture
US6729334B1 (en) * 1994-06-17 2004-05-04 Trudell Medical Limited Nebulizing catheter system and methods of use and manufacture
US5544648A (en) * 1995-05-12 1996-08-13 Cook Incorporated Device for intratracheal ventilation and intratracheal pulmonary ventilation including reverse venturi
US6082361A (en) * 1997-09-12 2000-07-04 Morejon; Orlando Endotracheal tube cleaning apparatus
US6595202B2 (en) * 1996-05-13 2003-07-22 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6086529A (en) * 1997-05-13 2000-07-11 Wisconsin Medical, Inc. Bronchoscopic manifold with compressible diaphragmatic valve for simultaneous airway instrumentation
US6237597B1 (en) * 1998-12-14 2001-05-29 Kovac Joann Endotracheal medication port adapter
US6102042A (en) * 1998-12-22 2000-08-15 Respironics, Inc. Insufflation system, attachment and method
US6257236B1 (en) * 1999-02-23 2001-07-10 Edward P Dutkiewicz Intubation device
US7402151B2 (en) * 2004-12-17 2008-07-22 Biocardia, Inc. Steerable guide catheters and methods for their use

Similar Documents

Publication Publication Date Title
RU95109450A (en) Methods for drug delivery to the respiratory system, the mode of delivery of the drug in one or both lungs of patients who are not inserted an endotracheal tube, METHOD aerosol delivery of drug in the lungs of patients: methods for drug delivery to a branched region of the respiratory system, the patient, the delivery catheter aerosol MEDICINES FOR LUNG PATIENTS (OPTIONS): CATHETER SYSTEM FOR DELIVERY OF AEROSOL OF MEDICINES IN LUNG PATIENTS, CATHETER SYSTEM A FOR DELIVERY aerosol therapy the patient's lungs, the suction catheter FOR A tracheal tube and method of making catheters for spraying liquids with gas
AU700225B2 (en) Nebulizing catheter system and methods of use and manufacture
US7472705B2 (en) Methods of forming a nebulizing catheter
US5642730A (en) Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister
AU2016225798B2 (en) Miniature fluid atomizer
US8146587B2 (en) Method for nasal irrigation and drug delivery
US6766801B1 (en) Intra-tracheal aerosol delivery system and method of using same
AU740924B2 (en) Nebulizing catheter system and methods of use and manufacture
CA2596438C (en) Nebulizing catheter system and methods of use and manufacture
EP4436638A1 (en) Tracheal administering device and atomizing catheter
JP2019005589A (en) Miniature fluid atomizer
JP2017140359A (en) Miniature fluid atomizer