RU95103852A - Immunosorbent for preparing monospecific antiserum to human transthyretin - Google Patents

Immunosorbent for preparing monospecific antiserum to human transthyretin

Info

Publication number
RU95103852A
RU95103852A RU95103852/14A RU95103852A RU95103852A RU 95103852 A RU95103852 A RU 95103852A RU 95103852/14 A RU95103852/14 A RU 95103852/14A RU 95103852 A RU95103852 A RU 95103852A RU 95103852 A RU95103852 A RU 95103852A
Authority
RU
Russia
Prior art keywords
immunosorbent
human transthyretin
preparing
proteins
specific activity
Prior art date
Application number
RU95103852/14A
Other languages
Russian (ru)
Other versions
RU2088937C1 (en
Inventor
Т.А. Иванина
В.А. Алешкин
Ю.Н. Лященко
В.Б. Хватов
Original Assignee
Московский городской научно-исследовательский институт скорой помощи им.Н.В.Склифосовского
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Московский городской научно-исследовательский институт скорой помощи им.Н.В.Склифосовского filed Critical Московский городской научно-исследовательский институт скорой помощи им.Н.В.Склифосовского
Priority to RU95103852A priority Critical patent/RU2088937C1/en
Publication of RU95103852A publication Critical patent/RU95103852A/en
Application granted granted Critical
Publication of RU2088937C1 publication Critical patent/RU2088937C1/en

Links

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

FIELD: medicine, immunology. SUBSTANCE: for preparing universal sorbent that increases specific activity of antisera to the human transthyretin proteins of "washing off" fibrinolytically active human plasma blood and ovalbumin were used. Total concentration of proteins is 75-110 mg/ml. Glutaric aldehyde is used as cross-linking agent at final concentration 0.7-0.8 vol. %. Invention can be used for immunodiagnosticum preparing. EFFECT: increased specific activity of sera to human transthyretin.

Claims (1)

Изобретение относится к иммунологии и может быть использовано при производстве иммуно-диагностикумов. Задачей изобретения является создание универсального иммуносорбента, повывающего специфическую активность антисывороток к транстиретину человека. Для приготовления такого сорбента используют белки "промывную" фибринолитически активной плазмы крови человека и овальбумин. Общая концентрация белков составляет 75 - 110 мг/мл. В качестве сшивающего агента применяется глутаровый альдегид в конечной концентрации 0,7- 0,8 объемных %.The invention relates to immunology and can be used in the production of immuno-diagnosticums. The objective of the invention is the creation of a universal immunosorbent that induces the specific activity of antisera to human transthyretin. For the preparation of such an sorbent, “wash” proteins of fibrinolytically active human blood plasma and ovalbumin are used. The total protein concentration is 75-110 mg / ml. Glutaraldehyde is used as a crosslinking agent in a final concentration of 0.7--0.8 volume%.
RU95103852A 1995-03-16 1995-03-16 Immunosorbent for preparing monospecific antiserum to the human transthyretine RU2088937C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95103852A RU2088937C1 (en) 1995-03-16 1995-03-16 Immunosorbent for preparing monospecific antiserum to the human transthyretine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95103852A RU2088937C1 (en) 1995-03-16 1995-03-16 Immunosorbent for preparing monospecific antiserum to the human transthyretine

Publications (2)

Publication Number Publication Date
RU95103852A true RU95103852A (en) 1997-06-10
RU2088937C1 RU2088937C1 (en) 1997-08-27

Family

ID=20165720

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95103852A RU2088937C1 (en) 1995-03-16 1995-03-16 Immunosorbent for preparing monospecific antiserum to the human transthyretine

Country Status (1)

Country Link
RU (1) RU2088937C1 (en)

Also Published As

Publication number Publication date
RU2088937C1 (en) 1997-08-27

Similar Documents

Publication Publication Date Title
DE69822665D1 (en) USE OF 9-DESOXY-2 ', 9-ALPHA-METHANO-3-OXA-4,5,6-TRINOR-3,7- (1', 3'-INTERPHENYLENE) -13,14-DIHYDROPROSTAGLANDIN-F1 FOR TREATMENT OF PERIPHERAL VASCULAR DISEASES
CH630115A5 (en) USE OF PREPARATIONS WITH AFFINITY TO THE HEPATITISVIRUS FOR THE REMOVAL OR CONCENTRATION OF HEPATITISVIRUS FROM OR IN MIXED BIOLOGICAL MATERIALS.
DK614987D0 (en) SYNTHETIC HTLV-III PEPTIDES, PREPARATIONS AND APPLICATIONS THEREOF
Ikeda Cystatin capture enzyme-linked immunosorbent assay for immunodiagnosis of human paragonimiasis and fascioliasis.
ATE407149T1 (en) DETOXIFICATION THROUGH F(AB')2 FRAGMENTS ADMINISTERED INTRAMUSCULARLY
RU95103852A (en) Immunosorbent for preparing monospecific antiserum to human transthyretin
Ostlund Jr Immunosorbent Chemistry: A Study of Agarose‐Based Column Sorbents for the Removal of Low‐Density Lipoprotein (LDL) from Blood
ES2180750T3 (en) CONJUGATED OF AN ACTIVE PRINCIPLE, A POLIETER AND, IF CASE, A NATIVE PROTEIN NOT CONSIDERED AS EXOGENA.
Dissous et al. Biochemical studies on the 30–40 kDa Schistosoma mansoni surface antigens
Olivos-García et al. Amebic cysteine proteinase 2 (EhCP2) plays either a minor or no role in tissue damage in acute experimental amebic liver abscess in hamsters
FI881122A (en) Method for isolating basement membrane proteins from human and animal tissues
Ekramoddoullah et al. Isolation of allergenically active cytochrome c from Kentucky blue grass pollen
EP0313005A3 (en) Method for detecting carcinomatous and precarcinomatous colo-rectal disease
JPS58501543A (en) Improvements regarding human interferon protein and antibodies against human interferon protein
BG96324A (en) PHARMACOLOGY ACTIVE SUBSTANCE VRS, METHOD OF ITS OBTAINMENT AND ITS THERAPEUTIC APPLICATION
WO1996032133A3 (en) Conjugate for treating inflammatory, infectious and/or skin diseases
CN103087194A (en) Anti-blood-cycle-venin egg yolk antibody and application thereof
SE8102267L (en) PROCEDURE FOR THE PREPARATION OF NON-COAGULATED BLOOD MEDIUM PROTEOLYTIC ENZYMES AND PROTEIN CONCENTRATE MADE THEREOF
RU2157693C1 (en) Method for treating the cases of virus-induced animal diseases
ATE207119T1 (en) THE PRODUCTION OF HUMAN MONOCLONAL ANTIBODIES ACTIVE AGAINST THE SURFACE ANTIGEN OF HEPATITIS B
JPS57142561A (en) Blood coagulation promoting agent for serum separation and its manufacture
JP3073501B2 (en) Binding of immune complexes by modified forms of C-reactive protein
RU2138812C1 (en) METHOD OF PREPARING SPECIFICALLY REACTING IN REACTION ABSORPTION-ELUTION SERA ANTI-A (α), ANTI-B (β) IN DETECTION OF ANTIGENS A, B IN HUMAN EXCRETION TRACES
Mostofa Biological studies on abomasal acid protease precursors in domestic ruminants
JPS57206623A (en) Remedy for allergic disease