RU95103852A - Immunosorbent for preparing monospecific antiserum to human transthyretin
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Immunosorbent for preparing monospecific antiserum to human transthyretin
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RU95103852A
RU95103852ARU95103852/14ARU95103852ARU95103852ARU 95103852 ARU95103852 ARU 95103852ARU 95103852/14 ARU95103852/14 ARU 95103852/14ARU 95103852 ARU95103852 ARU 95103852ARU 95103852 ARU95103852 ARU 95103852A
Московский городской научно-исследовательский институт скорой помощи им.Н.В.Склифосовского
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Priority to RU95103852ApriorityCriticalpatent/RU2088937C1/en
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Medicines Containing Material From Animals Or Micro-Organisms
(AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Abstract
FIELD: medicine, immunology. SUBSTANCE: for preparing universal sorbent that increases specific activity of antisera to the human transthyretin proteins of "washing off" fibrinolytically active human plasma blood and ovalbumin were used. Total concentration of proteins is 75-110 mg/ml. Glutaric aldehyde is used as cross-linking agent at final concentration 0.7-0.8 vol. %. Invention can be used for immunodiagnosticum preparing. EFFECT: increased specific activity of sera to human transthyretin.
Claims (1)
Изобретение относится к иммунологии и может быть использовано при производстве иммуно-диагностикумов. Задачей изобретения является создание универсального иммуносорбента, повывающего специфическую активность антисывороток к транстиретину человека. Для приготовления такого сорбента используют белки "промывную" фибринолитически активной плазмы крови человека и овальбумин. Общая концентрация белков составляет 75 - 110 мг/мл. В качестве сшивающего агента применяется глутаровый альдегид в конечной концентрации 0,7- 0,8 объемных %.The invention relates to immunology and can be used in the production of immuno-diagnosticums. The objective of the invention is the creation of a universal immunosorbent that induces the specific activity of antisera to human transthyretin. For the preparation of such an sorbent, “wash” proteins of fibrinolytically active human blood plasma and ovalbumin are used. The total protein concentration is 75-110 mg / ml. Glutaraldehyde is used as a crosslinking agent in a final concentration of 0.7--0.8 volume%.
RU95103852A1995-03-161995-03-16Immunosorbent for preparing monospecific antiserum to the human transthyretine
RU2088937C1
(en)
USE OF 9-DESOXY-2 ', 9-ALPHA-METHANO-3-OXA-4,5,6-TRINOR-3,7- (1', 3'-INTERPHENYLENE) -13,14-DIHYDROPROSTAGLANDIN-F1 FOR TREATMENT OF PERIPHERAL VASCULAR DISEASES
METHOD OF PREPARING SPECIFICALLY REACTING IN REACTION ABSORPTION-ELUTION SERA ANTI-A (α), ANTI-B (β) IN DETECTION OF ANTIGENS A, B IN HUMAN EXCRETION TRACES