RU94036002A - Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition - Google Patents

Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition

Info

Publication number
RU94036002A
RU94036002A RU94036002/13A RU94036002A RU94036002A RU 94036002 A RU94036002 A RU 94036002A RU 94036002/13 A RU94036002/13 A RU 94036002/13A RU 94036002 A RU94036002 A RU 94036002A RU 94036002 A RU94036002 A RU 94036002A
Authority
RU
Russia
Prior art keywords
phe
cys
glu
gly
asn
Prior art date
Application number
RU94036002/13A
Other languages
Russian (ru)
Inventor
Норрис Фанни
Dk]
Норрис Келль
Эрик Бьерн Серен
Кристиан Петерсен Ларс
Вильстед Ольсен Оле
Кеймирон Фостер Дональд
Энн Спричер Синди
Us]
Original Assignee
Ново Нордиск А/С (DK)
Ново Нордиск А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ново Нордиск А/С (DK), Ново Нордиск А/С filed Critical Ново Нордиск А/С (DK)
Priority to RU94036002/13A priority Critical patent/RU94036002A/en
Publication of RU94036002A publication Critical patent/RU94036002A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

FIELD: biochemistry, enzymology. SUBSTANCE: inhibitor of human protease of Kunits type has the following sequence of amino acid residues: Leu-Pro-Asn-Val-Cys-Ala-Phe-Pro-Met-Glu-Lys-Gly-Pro-Cys-Gln- -Thr-Tyr-Met-Thr-Arg-Trp-Phe-Phe-Asn-Phe-Glu-Thr-Gly-Glu-Cys- -Glu-Leu-Phe-Ala-Tyr-Gly-Gly-Cys-Gly-Gly-Asn-Ser-Asn-Asn-Phe- -Leu-Arg-Lys-Glu-Lys-Cys-Glu-Lys-Phe-Cys-Lys-Phe-Thr (sequence at identification number 1), or its form showing property of protease inhibitor. EFFECT: enhanced inhibiting activity.

Claims (1)

Ингибитор протеазы человека типа Кунитца содержит следующую последовательность аминокислотных остатков: Leu Pro Asn Val Cys Ala Phe Pro Met Glu Lys Gly Pro Cys Gln Thr Tyr Met Thr Arg Trp Phe Phe Asn Phe Glu Thr Gly Glu Cys Glu Leu Phe Ala Tyr Gly Gly Cys Gly Gly Asn Ser Asn Asn Phe Leu Arg Lys Glu Lуs Cys Glu Lys Phe Cys Lys Phe Thr (последовательность с номером идентификации 1) или его форма, обладающая свойствами ингибитора протеазы.The Kunitz-type human protease inhibitor contains the following sequence of amino acid residues: Leu Pro Asn Val Cys Ala Phe Pro Met Glu Lys Gly Pro Cys Gln Thr Tyr Met Thr Arg Trp Phe Phe Asn Phe Glu Thr Gly Glu Cys Glu Leu Phe Ala Tyr Gly Gly Cys Gly Gly Asn Ser Asn Asn Phe Leu Arg Lys Glu Lus Cys Glu Lys Phe Cys Lys Phe Thr (sequence with identification number 1) or a form thereof having the properties of a protease inhibitor.
RU94036002/13A 1992-01-07 1993-01-07 Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition RU94036002A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU94036002/13A RU94036002A (en) 1992-01-07 1993-01-07 Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKDK92/00003 1992-01-07
RU94036002/13A RU94036002A (en) 1992-01-07 1993-01-07 Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition

Publications (1)

Publication Number Publication Date
RU94036002A true RU94036002A (en) 1996-09-27

Family

ID=48451318

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94036002/13A RU94036002A (en) 1992-01-07 1993-01-07 Protease inhibitor, dna, vector, cell, method of inhibitor preparing, pharmaceutical composition

Country Status (1)

Country Link
RU (1) RU94036002A (en)

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