RU94026250A - DERIVATIVES OF NITROXIALKYLAMIDE - Google Patents

DERIVATIVES OF NITROXIALKYLAMIDE

Info

Publication number
RU94026250A
RU94026250A RU94026250/04A RU94026250A RU94026250A RU 94026250 A RU94026250 A RU 94026250A RU 94026250/04 A RU94026250/04 A RU 94026250/04A RU 94026250 A RU94026250 A RU 94026250A RU 94026250 A RU94026250 A RU 94026250A
Authority
RU
Russia
Prior art keywords
derivatives
nitroxialkylamide
angina pectoris
alkylene group
heterocyclic
Prior art date
Application number
RU94026250/04A
Other languages
Russian (ru)
Other versions
RU2098406C1 (en
Inventor
Исихара Садао
Сайто Фудзио
Катаока Митсуру
Койке Хироюки
Мийаке Сигеки
Мизуно Хироси
Original Assignee
Санкио Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санкио Компани Лимитед filed Critical Санкио Компани Лимитед
Priority claimed from PCT/JP1992/001419 external-priority patent/WO1993009085A1/en
Publication of RU94026250A publication Critical patent/RU94026250A/en
Application granted granted Critical
Publication of RU2098406C1 publication Critical patent/RU2098406C1/en

Links

Claims (1)

Производные нитроксиалкиламида, имеющие общую формулу:
R1 - (А)n -CONH-B-ONO2, (I)
где R1 - необязательно замещенная гетероциклическая, гетероциклическая окси, арилокси-или арилтиогруппа, A - C1 - C4-алкиленовая группа, B - C1 - C4-алкиленовая группа, n равно 0 или 1. Соединения предлагаемого изобретения обладают превосходным сосудорасширяющим действием для коллатеральных сосудов и противостенокардическим действием и являются полезными в качестве терапевтических агентов от стенокардии.Nitroxyalkylamide derivatives having the general formula:
R 1 - (A) n -CONH-B-ONO 2 , (I)
where R 1 is an optionally substituted heterocyclic, heterocyclic hydroxy, aryloxy or arylthio group, A is a C 1 to C 4 alkylene group, B is a C 1 to C 4 alkylene group, n is 0 or 1. The compounds of the present invention have an excellent vasodilator an action for collateral vessels; and an anti-angina pectoris and are useful as therapeutic agents for angina pectoris.
RU9494026250A 1991-11-07 1992-11-02 Derivatives of nitroxyalkylamide and a method of their synthesis RU2098406C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3-291410 1991-11-07
JP29141091 1991-11-07
PCT/JP1992/001419 WO1993009085A1 (en) 1991-11-07 1992-11-02 Nitroxyalkylamide derivative

Publications (2)

Publication Number Publication Date
RU94026250A true RU94026250A (en) 1995-08-20
RU2098406C1 RU2098406C1 (en) 1997-12-10

Family

ID=17768533

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9494026250A RU2098406C1 (en) 1991-11-07 1992-11-02 Derivatives of nitroxyalkylamide and a method of their synthesis

Country Status (18)

Country Link
US (1) US5580893A (en)
EP (1) EP0641768B1 (en)
JP (1) JP3454531B2 (en)
KR (1) KR100230633B1 (en)
AT (1) ATE155774T1 (en)
AU (1) AU662939B2 (en)
CA (1) CA2123101C (en)
CZ (1) CZ281710B6 (en)
DE (1) DE69221167T2 (en)
DK (1) DK0641768T3 (en)
ES (1) ES2106199T3 (en)
FI (1) FI942070A0 (en)
GR (1) GR3025056T3 (en)
HK (1) HK1001089A1 (en)
HU (1) HU220222B (en)
NO (1) NO305551B1 (en)
RU (1) RU2098406C1 (en)
WO (1) WO1993009085A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
GT200600159A (en) * 2005-04-22 2007-03-14 BENZODIOXAN AND BENZODIOXOLAN DERIVATIVES AND USES OF THE SAME
US8492428B2 (en) 2005-09-20 2013-07-23 Mayo Foundation For Medical Education And Research Small-molecule botulinum toxin inhibitors
NL2000351C2 (en) * 2005-12-22 2007-09-11 Pfizer Prod Inc Estrogen modulators.
KR100698701B1 (en) * 2006-03-28 2007-03-23 삼성에스디아이 주식회사 Organic Light Emitting Display and Driving Method Thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
JPS539775A (en) * 1976-07-15 1978-01-28 Chugai Pharmaceut Co Ltd Pyridine derivatives and their preparation
JPS57197275A (en) * 1981-05-29 1982-12-03 Nippon Zeon Co Ltd Production of alpha-lactone
DE3443998A1 (en) * 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim AMINO-PROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND INTERMEDIATE PRODUCTS
JPS62286968A (en) * 1986-06-04 1987-12-12 Chugai Pharmaceut Co Ltd Novel nicotinic acid amide derivative
DE3705622A1 (en) * 1987-02-21 1988-09-01 Boehringer Mannheim Gmbh NEW AMINO-PROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND INTERMEDIATE PRODUCTS
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
JPS6456667A (en) * 1987-08-28 1989-03-03 Hokuriku Pharmaceutical Nitric acid ester derivative
NL8802276A (en) * 1988-09-15 1990-04-02 Cedona Pharm Bv MEDICINAL PRODUCT WITH RELAXING EFFECT, CONTAINING A NITRATE ESTER AS ACTIVE SUBSTANCE.
JPH02207072A (en) * 1989-02-06 1990-08-16 Sagami Kasei Kogyo Kk Nitration of pyridinecarboxylic acid amide alcohols
US5298516A (en) * 1991-03-27 1994-03-29 Sankyo Company, Limited Thiazolidone compounds and method of using the same as a vasodilator
JP2777000B2 (en) * 1991-06-27 1998-07-16 ローム株式会社 Image sensor
JP3361836B2 (en) * 1991-07-04 2003-01-07 三共株式会社 Amino acid derivatives

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