RU93052669A - METHOD FOR PRODUCING SPECIFIC LACTOGLOBULIN - Google Patents

METHOD FOR PRODUCING SPECIFIC LACTOGLOBULIN

Info

Publication number
RU93052669A
RU93052669A RU93052669/14A RU93052669A RU93052669A RU 93052669 A RU93052669 A RU 93052669A RU 93052669/14 A RU93052669/14 A RU 93052669/14A RU 93052669 A RU93052669 A RU 93052669A RU 93052669 A RU93052669 A RU 93052669A
Authority
RU
Russia
Prior art keywords
immunization
antigen
lactoglobulin
cows
producing specific
Prior art date
Application number
RU93052669/14A
Other languages
Russian (ru)
Other versions
RU2090193C1 (en
Inventor
С.В. Соболева
А.П. Шепелев
Т.А. Федорова
В.С. Гугуева
Л.Н. Чернавская
Э.А. Яговкин
А.К. Адамов
Ю.М. Ломов
Original Assignee
Научно-производственное объединение "Биопрепарат"
Концерн "Иммуноген"
Filing date
Publication date
Application filed by Научно-производственное объединение "Биопрепарат", Концерн "Иммуноген" filed Critical Научно-производственное объединение "Биопрепарат"
Priority to RU93052669A priority Critical patent/RU2090193C1/en
Priority claimed from RU93052669A external-priority patent/RU2090193C1/en
Application granted granted Critical
Publication of RU2090193C1 publication Critical patent/RU2090193C1/en
Publication of RU93052669A publication Critical patent/RU93052669A/en

Links

Claims (3)

1. Способ получения специфического лактоглобулина путем многократной внутримышечной иммунизации глубокостельных коров корпускулярным микробным антигеном с последующим сбором молозива, отделением лактосыворотки, выделением и стерилизацией иммунных комплексов, отличающийся тем, что, с целью повышения выхода целевого продукта, циклы иммунизации проводят с 1 - 2 - недельным интервалом из расчета разовой дозы корпускулярного антигена 20 - 30 млрд. м.т. на корову, при этом кратность иммунизации устанавливают по формуле n = 3 + t, где n - количество циклов иммунизации, t - число недель до растела, определяемое после третьей иммунизации.1. A method for producing specific lactoglobulin by repeated intramuscular immunization of deep-body cows with a corpuscular microbial antigen followed by colostrum collection, lactoserum separation, isolation and sterilization of immune complexes, characterized in that, in order to increase the yield of the target product, immunization cycles are carried out with 1 - 2 - week the interval from the calculation of a single dose of a corpuscular antigen of 20 - 30 billion mt per cow, while the immunization rate is set according to the formula n = 3 + t, where n is the number of immunization cycles, t is the number of weeks before growing, determined after the third immunization. 2. Способ по п.1, отличающийся тем, что коров иммунизируют антигеном, дополнительно содержащим растворимый антиген из расчета разовой дозы 10 - 15 чел/доз на корову. 2. The method according to claim 1, characterized in that the cows are immunized with an antigen additionally containing a soluble antigen based on a single dose of 10-15 people / dose per cow. 3. Способ по п.2, отличающийся тем, что в качестве растворимого антигена используют химическую холерную вакцину. 3. The method according to claim 2, characterized in that a chemical cholera vaccine is used as a soluble antigen.
RU93052669A 1993-11-22 1993-11-22 Method for producing specific lactoglobulin RU2090193C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU93052669A RU2090193C1 (en) 1993-11-22 1993-11-22 Method for producing specific lactoglobulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU93052669A RU2090193C1 (en) 1993-11-22 1993-11-22 Method for producing specific lactoglobulin

Publications (2)

Publication Number Publication Date
RU2090193C1 RU2090193C1 (en) 1997-09-20
RU93052669A true RU93052669A (en) 1997-11-10

Family

ID=20149447

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93052669A RU2090193C1 (en) 1993-11-22 1993-11-22 Method for producing specific lactoglobulin

Country Status (1)

Country Link
RU (1) RU2090193C1 (en)

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