RU93005077ARU93005077/04ARU93005077ARU93005077ARU 93005077 ARU93005077 ARU 93005077ARU 93005077/04 ARU93005077/04 ARU 93005077/04ARU 93005077 ARU93005077 ARU 93005077ARU 93005077 ARU93005077 ARU 93005077A
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Application filed by Стерлинг Уинтроп, Инк.filedCriticalСтерлинг Уинтроп, Инк.
Priority claimed from PCT/US1991/005531external-prioritypatent/WO1992002534A2/en
Publication of RU93005077ApublicationCriticalpatent/RU93005077A/en
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Publication of RU2131436C1publicationCriticalpatent/RU2131436C1/en
Предлагаемое изобретение относится к соединениям, композициям и методам ингибирования экспрессии генов. Предлагаемые соединения включают: олигонуклеозидные последовательности, состоящие из примерно 6 - 200 оснований, с трехатомной межнуклеозидной связью или олигонуклеотидные последовательности, состоящие из примерно 9 - 200 оснований с диолом у любого или обоих их концов.The present invention relates to compounds, compositions and methods for inhibiting gene expression. The proposed compounds include: oligonucleoside sequences consisting of about 6 to 200 bases, with a triatomic internucleoside linkage, or oligonucleotide sequences consisting of about 9 to 200 bases with a diol at either or both of their ends.
RU93005077A1990-09-131991-08-02Nuclease-resistant oligonucleosides, method of preparing thereof, and nuclease-resistant nucleoside dimer
RU2131436C1
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