RU93004665A - MICROBIOLOGICAL METHOD FOR HYDROXYLATION OF NITROGEN-HETEROCYCLIC-CARBOXYLIC ACIDS - Google Patents

MICROBIOLOGICAL METHOD FOR HYDROXYLATION OF NITROGEN-HETEROCYCLIC-CARBOXYLIC ACIDS

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Publication number
RU93004665A
RU93004665A RU93004665/13A RU93004665A RU93004665A RU 93004665 A RU93004665 A RU 93004665A RU 93004665/13 A RU93004665/13 A RU 93004665/13A RU 93004665 A RU93004665 A RU 93004665A RU 93004665 A RU93004665 A RU 93004665A
Authority
RU
Russia
Prior art keywords
carboxylic acids
nitrogen
hydroxylation
heterocyclic
microbiological method
Prior art date
Application number
RU93004665/13A
Other languages
Russian (ru)
Other versions
RU2122029C1 (en
Inventor
Кинер Андреас
Чех Андреас
Тиншерт Андреас
Хайнцман Клаус
Original Assignee
Лонца Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лонца Аг filed Critical Лонца Аг
Publication of RU93004665A publication Critical patent/RU93004665A/en
Application granted granted Critical
Publication of RU2122029C1 publication Critical patent/RU2122029C1/en

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Claims (1)

Изобретение касается нового микробиологического метода получения гидрокси-азотсодержащих гетероциклических карбоновых кислот и их растворимых солей с общей формулой I
Figure 00000001

на основе соответствующих азотсодержащих гетероциклических карбоновых кислот, а также нового типа микроорганизмов, используемых для данного процесса.The invention relates to a new microbiological method for producing hydroxy-nitrogen-containing heterocyclic carboxylic acids and their soluble salts with the general formula I
Figure 00000001

based on the corresponding nitrogen-containing heterocyclic carboxylic acids, as well as a new type of microorganism used for this process.
RU93004665/13A 1992-03-04 1993-03-01 Method of producing nitrogen-containing heterocyclic carboxylic acids containing hydroxyl group or their soluble salts, strain of bacterium for metabolism of nitrogen-containing heterocyclic carboxylic acids to hydroxyl group-containing nitrogen-containing heterocyclic carboxylic acids RU2122029C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH672/92 1992-03-04
CH67292 1992-03-04

Publications (2)

Publication Number Publication Date
RU93004665A true RU93004665A (en) 1997-01-20
RU2122029C1 RU2122029C1 (en) 1998-11-20

Family

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RU93004665/13A RU2122029C1 (en) 1992-03-04 1993-03-01 Method of producing nitrogen-containing heterocyclic carboxylic acids containing hydroxyl group or their soluble salts, strain of bacterium for metabolism of nitrogen-containing heterocyclic carboxylic acids to hydroxyl group-containing nitrogen-containing heterocyclic carboxylic acids

Country Status (17)

Country Link
US (2) US5306630A (en)
EP (1) EP0559116B1 (en)
JP (1) JPH06199797A (en)
KR (1) KR100274205B1 (en)
CN (1) CN1077748A (en)
AT (1) ATE153698T1 (en)
CA (1) CA2091005C (en)
CZ (1) CZ282939B6 (en)
DE (1) DE59306547D1 (en)
DK (1) DK0559116T3 (en)
ES (1) ES2101887T3 (en)
GE (1) GEP19991710B (en)
GR (1) GR3024286T3 (en)
LT (1) LT3114B (en)
LV (1) LV10504B (en)
RU (1) RU2122029C1 (en)
SK (1) SK279322B6 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9426293D0 (en) * 1994-12-28 1995-02-22 Zeneca Ltd Composition,compound and use
US5763232A (en) * 1996-02-15 1998-06-09 Mitsubishi Chemical Corporation Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound
JP4972261B2 (en) * 1999-08-27 2012-07-11 ライフ テクノロジーズ コーポレーション Metal binding compounds and their use in cell culture media compositions
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
AU2002220603A1 (en) * 2000-10-06 2002-04-15 Lonza A.G. Biotechnological method for preparing carboxylic acids with a hydroxy-nitrogen heterocycle
NZ584157A (en) * 2007-09-27 2012-04-27 Toyama Chemical Co Ltd Organic amine salt of 6-fluoro-3-hydroxy-2-pyrazinecarbonitrile and method for producing the same
MX2013005179A (en) * 2010-11-12 2013-07-05 Fujifilm Corp Pyrazino[2,3-d]isooxazole derivative.

Family Cites Families (16)

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US4081451A (en) * 1975-03-20 1978-03-28 Schering Corporation Process for preparing 2-halogeno nicotinic acids
JPS6061567A (en) * 1983-09-14 1985-04-09 ロンザ　リミテツド Manufacture of 2-hydroxypyridine from 2-pyridinecarboxylic acid-n-oxide
CH658866A5 (en) * 1984-02-21 1986-12-15 Lonza Ag METHOD FOR PRODUCING 6-HYDROXYNICOTINIC ACID.
CH658867A5 (en) * 1984-02-22 1986-12-15 Lonza Ag METHOD FOR PRODUCING 6-HYDROXYNICOTINIC ACID.
IN170700B (en) * 1989-12-20 1992-05-02 Lonza Ag
US5236832A (en) * 1990-02-13 1993-08-17 Lonza, Ltd. Microbiological oxidation of methyl groups in heterocycles
US5242816A (en) * 1990-07-10 1993-09-07 Lonza Ltd. Microbiological oxidation of alkyl groups in heterocycles
CZ279464B6 (en) * 1990-09-24 1995-05-17 Lonza A.G. HYDROXYLATION PROCESS OF METHYL GROUPS IN AROMATIC HETERO CYCLES, HYBRID PLASMIDS pLO5 AND pLO4 AND MICRO-ORGANISMS PSEUDOMONA PUTIDA AND ESCHERICHIA COLI
CZ279488B6 (en) * 1990-09-25 1995-05-17 Lonza A.G. Micro-organisms rhodococcus erythropolis and arthrobacter sp. as well as micro-biological preparation of hydroxylated pyrazines and quinoxalines.
KR100233330B1 (en) * 1991-02-04 1999-12-01 하인즈 모제르 Microbiological process for the production of 6-hydroxypicolinic acid
US5238830A (en) * 1991-02-04 1993-08-24 Lonza Ltd. Microbiological process for the production of 6-hydroxypicolinic acid
JPH0740951B2 (en) * 1991-03-30 1995-05-10 池田食研株式会社 Method for producing hydroxide of nitrogen-containing heterocyclic compound by microorganism
JPH0728750B2 (en) * 1991-03-30 1995-04-05 池田食研株式会社 Method for producing hydroxide of pyrazinic acid by microorganism
FI922125A (en) * 1991-06-21 1992-12-22 Lonza Ag MICROBIDOGRAPHIC FOERFARANDE FOER FRAMSTAELLNING AV 5-HYDROXIPYRAZINKARBOXYLSYRA
MX9204902A (en) * 1991-08-30 1993-05-01 Lonza Ag MICROBIOLOGICAL PROCEDURE FOR THE PREPARATION OF 6-HYDROXIPIRAZINCARBOXILIC ACID.
JP2583719B2 (en) * 1992-08-10 1997-02-19 株式会社日立製作所 Gas controlled output stabilized gas laser system

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