RU93004649A - TAXAN DERIVATIVES, METHOD OF THEIR PRODUCTION AND USE IN ONCOLOGY, PHARMACOMPOSITION - Google Patents

TAXAN DERIVATIVES, METHOD OF THEIR PRODUCTION AND USE IN ONCOLOGY, PHARMACOMPOSITION

Info

Publication number
RU93004649A
RU93004649A RU93004649/04A RU93004649A RU93004649A RU 93004649 A RU93004649 A RU 93004649A RU 93004649/04 A RU93004649/04 A RU 93004649/04A RU 93004649 A RU93004649 A RU 93004649A RU 93004649 A RU93004649 A RU 93004649A
Authority
RU
Russia
Prior art keywords
production
pharmacomposition
oncology
taxan derivatives
formula
Prior art date
Application number
RU93004649/04A
Other languages
Russian (ru)
Other versions
RU2112770C1 (en
Inventor
Бомбарделли Эцо
Габетта Бруно
Original Assignee
Индена С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI920526A external-priority patent/IT1254515B/en
Application filed by Индена С.П.А. filed Critical Индена С.П.А.
Publication of RU93004649A publication Critical patent/RU93004649A/en
Application granted granted Critical
Publication of RU2112770C1 publication Critical patent/RU2112770C1/en

Links

Claims (1)

Получение новых 3,11-циклотаксанов, имеющих общую формулу I. Циклотаксан формулы Iа может быть выделен из растений рода Тахия (соединение формулы I, в котором R'=R"=H). Новые циклотаксаны формулы I обладают противоопухолевой. активностью.Production of new 3,11-cyclotaxanes having the general formula I. The cyclotaxan of formula Ia can be isolated from plants of the genus Tachia (compound of formula I, in which R ' = R " = H). New cyclotaxanes of formula I have antitumor activity.
RU93004649A 1992-03-06 1993-03-04 Taxane derivatives, method of their preparing, pharmaceutical composition RU2112770C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITM192A000526 1992-03-06
ITMI920526A IT1254515B (en) 1992-03-06 1992-03-06 TASSANI OF ONCOLOGICAL INTEREST, THEIR METHOD OF PREPARATION AND USE

Publications (2)

Publication Number Publication Date
RU93004649A true RU93004649A (en) 1996-06-20
RU2112770C1 RU2112770C1 (en) 1998-06-10

Family

ID=11362316

Family Applications (2)

Application Number Title Priority Date Filing Date
RU93004623A RU2119485C1 (en) 1992-03-06 1993-03-04 Derivatives of taxane-iii, methods of their synthesis and a pharmaceutical composition
RU93004649A RU2112770C1 (en) 1992-03-06 1993-03-04 Taxane derivatives, method of their preparing, pharmaceutical composition

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU93004623A RU2119485C1 (en) 1992-03-06 1993-03-04 Derivatives of taxane-iii, methods of their synthesis and a pharmaceutical composition

Country Status (15)

Country Link
US (1) US5250722A (en)
EP (1) EP0559018B1 (en)
JP (1) JPH0641010A (en)
KR (1) KR100255524B1 (en)
AT (1) ATE137734T1 (en)
CA (1) CA2091002C (en)
DE (2) DE69302508T2 (en)
DK (1) DK0559018T3 (en)
ES (1) ES2049690T3 (en)
FI (1) FI112208B (en)
GR (2) GR930300141T1 (en)
HK (1) HK1007556A1 (en)
IT (1) IT1254515B (en)
NO (1) NO178965C (en)
RU (2) RU2119485C1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5475120A (en) * 1990-11-02 1995-12-12 University Of Florida Method for the isolation and purification of taxol and its natural analogues
JP2646942B2 (en) * 1991-08-12 1997-08-27 松下電器産業株式会社 Device and method for punching electronic component with guard
IT1261667B (en) * 1993-05-20 1996-05-29 TAX FOR ANTI-CANCER ACTIVITIES.
US5628978A (en) * 1994-12-23 1997-05-13 Intevep, S.A. MTW zeolite for cracking feedstock into olefins and isoparaffins
US6177456B1 (en) 1995-10-02 2001-01-23 Xechem International, Inc. Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
US5840748A (en) * 1995-10-02 1998-11-24 Xechem International, Inc. Dihalocephalomannine and methods of use therefor
US5654448A (en) * 1995-10-02 1997-08-05 Xechem International, Inc. Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
US5854278A (en) * 1995-12-13 1998-12-29 Xechem International, Inc. Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US5807888A (en) * 1995-12-13 1998-09-15 Xechem International, Inc. Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
ATE196844T1 (en) * 1996-05-22 2000-10-15 Protarga Inc COMPOSITIONS CONTAINING CONJUGATES OF CIS-DOCOSAHEXAENOIC ACID AND TAXOTERE
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
EP1427407A4 (en) 2001-03-23 2005-05-11 Luitpold Pharm Inc Fatty amine drug conjugates
ES2387562T3 (en) * 2001-03-23 2012-09-26 Luitpold Pharmaceuticals, Inc. Conjugates fatty alcohol-medication
US7201507B2 (en) 2003-12-25 2007-04-10 Ichikoh Industries, Ltd. Projector type vehicle light
JP4405279B2 (en) 2004-02-17 2010-01-27 市光工業株式会社 Projector type vehicle lamp
JP4954983B2 (en) 2005-05-18 2012-06-20 ファーマサイエンス・インコーポレイテッド BIR domain binding compound
BRPI0711591A2 (en) 2006-05-16 2011-11-16 Aegera Therapeutics Inc iap bir domain binding compound
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
CN105541631B (en) * 2015-10-26 2017-09-05 云南西力生物技术股份有限公司 Raw element A (spiratisanin A) of meadow sweet Ah Ti and preparation method thereof and the application on medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380916A (en) * 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives

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