RU93004577A - Derivatives of imidazole with a side chain of biphenylsulfonylurea - Google Patents

Derivatives of imidazole with a side chain of biphenylsulfonylurea

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Publication number
RU93004577A
RU93004577A RU93004577/04A RU93004577A RU93004577A RU 93004577 A RU93004577 A RU 93004577A RU 93004577/04 A RU93004577/04 A RU 93004577/04A RU 93004577 A RU93004577 A RU 93004577A RU 93004577 A RU93004577 A RU 93004577A
Authority
RU
Russia
Prior art keywords
biphenylsulfonylurea
side chain
imidazole
derivatives
biphenylsulfonylurethane
Prior art date
Application number
RU93004577/04A
Other languages
Russian (ru)
Other versions
RU2116300C1 (en
Inventor
Хайч Холгер
Хеннинг Райнер
Вагнер Адальберт
Герхардс Херманн
Бекер Райнхард
Шелькенс Бернвард
Original Assignee
Хехст АГ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Хехст АГ filed Critical Хехст АГ
Publication of RU93004577A publication Critical patent/RU93004577A/en
Application granted granted Critical
Publication of RU2116300C1 publication Critical patent/RU2116300C1/en

Links

Claims (1)

Предложены производные имидазола с боковой цепью бифенилсульфонилмочевины или бифенилсульфонилуретана, способ их получения и их применение. Соединения формулы
Figure 00000001

где R1 - например, этил, R2 - например, метил, n - например, O, R3 - например, COOH и R4 - например, SO2NHCONHCH3, представляют высокоактивные антагонисты ангиотензин-11-рецепторов.The proposed imidazole derivatives with a side chain of biphenylsulfonylurea or biphenylsulfonylurethane, a method for their preparation and their use. Compounds of formula
Figure 00000001

where R 1 - for example, ethyl, R 2 - for example, methyl, n - for example, O, R 3 - for example, COOH and R 4 - for example, SO 2 NHCONHCH 3 , are highly active angiotensin-11 receptor antagonists.
RU93004577A 1992-03-07 1993-03-05 Imidazole derivatives or their physiologically acceptable salts, method of their synthesis, agent for blood hypertension decrease and pharmaceutical composition for blood pressure decrease RU2116300C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4207241 1992-03-07
DEP4207241.7 1992-03-07

Publications (2)

Publication Number Publication Date
RU93004577A true RU93004577A (en) 1996-02-27
RU2116300C1 RU2116300C1 (en) 1998-07-27

Family

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Family Applications (1)

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RU93004577A RU2116300C1 (en) 1992-03-07 1993-03-05 Imidazole derivatives or their physiologically acceptable salts, method of their synthesis, agent for blood hypertension decrease and pharmaceutical composition for blood pressure decrease

Country Status (25)

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US (1) US5604251A (en)
EP (1) EP0560177B1 (en)
JP (1) JP3542813B2 (en)
KR (1) KR930019637A (en)
CN (1) CN1036341C (en)
AT (1) ATE230732T1 (en)
AU (1) AU663565B2 (en)
BR (1) BR9300761A (en)
CA (1) CA2091135A1 (en)
CZ (1) CZ281983B6 (en)
DE (1) DE59310323D1 (en)
DK (1) DK0560177T3 (en)
ES (1) ES2187501T3 (en)
FI (1) FI930970A (en)
HU (1) HUT64041A (en)
IL (1) IL104971A0 (en)
MA (1) MA22814A1 (en)
NO (1) NO303632B1 (en)
NZ (1) NZ247059A (en)
PH (1) PH31466A (en)
PL (1) PL173023B1 (en)
RU (1) RU2116300C1 (en)
SK (1) SK381192A3 (en)
TW (1) TW215434B (en)
ZA (1) ZA931585B (en)

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