RU92004544A - SUBSTITUTED DERIVATIVES OF BENZOLEMONALINES, METHOD FOR THEIR PRODUCTION, ANTI-SMALL COMPOSITION AND METHOD OF TREATMENT - Google Patents

SUBSTITUTED DERIVATIVES OF BENZOLEMONALINES, METHOD FOR THEIR PRODUCTION, ANTI-SMALL COMPOSITION AND METHOD OF TREATMENT

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Publication number
RU92004544A
RU92004544A RU92004544/33A RU92004544A RU92004544A RU 92004544 A RU92004544 A RU 92004544A RU 92004544/33 A RU92004544/33 A RU 92004544/33A RU 92004544 A RU92004544 A RU 92004544A RU 92004544 A RU92004544 A RU 92004544A
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RU
Russia
Prior art keywords
benzolemonalines
treatment
production
group
substituted derivatives
Prior art date
Application number
RU92004544/33A
Other languages
Russian (ru)
Inventor
Кон Кендзи
Окада Хироси
Original Assignee
Исихара Сангио Кайся, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Исихара Сангио Кайся, Лтд. filed Critical Исихара Сангио Кайся, Лтд.
Publication of RU92004544A publication Critical patent/RU92004544A/en

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Claims (1)

Изобретение обеспечивает получение замещенного производного бензоилмочевины общей формулы
Figure 00000001

где Q является группой - R1N(Z2)Z3 или -R2N(Z4)COR1N(Z2)Z3; R1 и R2 являются соответственно алкандиильными группами, которые могут иметь в качестве заместителей низшую алкилти- и фенильную группу; Z1 - Z4 являются, соответственно водородом или низшими алкильными группами; R1 и Z2 могут быть связаны друг с другом, образуя гетероциклическое кольцо с соседним атомом азота; X - галоген, низшая алкильная группа или группа CF3; Y - галоген, или его соли, эффективных в качестве противоопухолевых агентов; способ их получения; противоопухолевую композицию, включающую эти соединения, и промежуточный продукт для их получения.EFFECT: obtaining a substituted benzoylurea derivative of general formula
Figure 00000001

where Q is a group - R 1 N (Z 2 ) Z 3 or -R 2 N (Z 4 ) COR 1 N (Z 2 ) Z 3 ; R 1 and R 2 are respectively alkanediyl groups which may have a lower alkylthi and phenyl group as substituents; Z 1 - Z 4 are, respectively, hydrogen or lower alkyl groups; R 1 and Z 2 can be linked to each other, forming a heterocyclic ring with an adjacent nitrogen atom; X is a halogen, lower alkyl group or CF 3 group; Y is halogen, or a salt thereof, effective as antitumor agents; the way they are received; an antitumor composition comprising these compounds and an intermediate product for their preparation.
RU92004544/33A 1991-12-05 1992-12-04 SUBSTITUTED DERIVATIVES OF BENZOLEMONALINES, METHOD FOR THEIR PRODUCTION, ANTI-SMALL COMPOSITION AND METHOD OF TREATMENT RU92004544A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP360431/91 1991-12-05

Publications (1)

Publication Number Publication Date
RU92004544A true RU92004544A (en) 1995-06-19

Family

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