RU92004496A - NEW PIPERASINIL AND PIPERIDINYLCICLOGEXANOLS - Google Patents

NEW PIPERASINIL AND PIPERIDINYLCICLOGEXANOLS

Info

Publication number
RU92004496A
RU92004496A RU92004496/04A RU92004496A RU92004496A RU 92004496 A RU92004496 A RU 92004496A RU 92004496/04 A RU92004496/04 A RU 92004496/04A RU 92004496 A RU92004496 A RU 92004496A RU 92004496 A RU92004496 A RU 92004496A
Authority
RU
Russia
Prior art keywords
new
piperidinylciclogexanols
piperasinil
piperidinylcyclohexanol
anxiolytics
Prior art date
Application number
RU92004496/04A
Other languages
Russian (ru)
Other versions
RU2088574C1 (en
Inventor
Дж. МЭТТСОН Рональд
Д.Кэтт Джон
Original Assignee
Бристоль-Мейерз Сквивв Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристоль-Мейерз Сквивв Компани filed Critical Бристоль-Мейерз Сквивв Компани
Publication of RU92004496A publication Critical patent/RU92004496A/en
Application granted granted Critical
Publication of RU2088574C1 publication Critical patent/RU2088574C1/en

Links

Claims (1)

Новые пиперазинил и пиперидинилциклогексанолы, полезные в качестве анксиолитических средств, обладающие психотропными свойствами.New piperazinyl and piperidinylcyclohexanol, useful as anxiolytics, with psychotropic properties.
Figure 00000001
Figure 00000001
RU9292004496A 1991-12-13 1992-12-11 Piperazinyl- and piperidinylcyclohexanoles and their pharmaceutically acceptable salts, pharmaceutical composition and a method of serotoninergic neurotransmission increase RU2088574C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US806,989 1985-12-09
US80698991A 1991-12-13 1991-12-13
US806989 1991-12-13

Publications (2)

Publication Number Publication Date
RU92004496A true RU92004496A (en) 1996-01-10
RU2088574C1 RU2088574C1 (en) 1997-08-27

Family

ID=25195310

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9292004496A RU2088574C1 (en) 1991-12-13 1992-12-11 Piperazinyl- and piperidinylcyclohexanoles and their pharmaceutically acceptable salts, pharmaceutical composition and a method of serotoninergic neurotransmission increase

Country Status (25)

Country Link
US (2) US5387593A (en)
EP (1) EP0546583B1 (en)
JP (1) JP3197963B2 (en)
KR (1) KR100251667B1 (en)
AT (1) ATE138367T1 (en)
AU (1) AU661525B2 (en)
CA (1) CA2083913C (en)
CY (1) CY1943A (en)
CZ (1) CZ290056B6 (en)
DE (1) DE69210967T2 (en)
DK (1) DK0546583T3 (en)
EG (1) EG19999A (en)
ES (1) ES2088076T3 (en)
FI (1) FI925595A (en)
GR (1) GR3020239T3 (en)
HK (1) HK181396A (en)
HU (1) HU215963B (en)
IL (1) IL103875A (en)
MX (1) MX9207074A (en)
MY (1) MY110162A (en)
NO (1) NO301326B1 (en)
NZ (1) NZ245386A (en)
RU (1) RU2088574C1 (en)
TW (1) TW234120B (en)
ZA (1) ZA929008B (en)

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US6572880B2 (en) 1996-10-24 2003-06-03 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
US6479074B2 (en) 1996-10-24 2002-11-12 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
US6290986B1 (en) 1996-10-24 2001-09-18 Pharmaceutical Applications Associates, Llc Method and composition for transdermal administration of pharmacologic agents
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US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
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ID27178A (en) 1998-04-01 2001-03-08 Nortran Pharmaceuticals Inc COMPOUND AMINOSICLOHEXIC COMPOUNDS AND ITS USE
CA2360683A1 (en) 1999-01-28 2000-08-03 Joseph P. Yevich Antidepressant heterocyclic compounds
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
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US7524879B2 (en) 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
ES2188344B1 (en) * 2000-11-29 2004-09-16 Laboratorios Vita, S.A. COMPOUNDS DERIVED FROM BENZOTIOPHENE, ITS PROCEDURE FOR OBTAINING AND USING THEMSELVES.
GB0116594D0 (en) 2001-07-06 2001-08-29 Cancer Res Ventures Ltd Therapeutic compounds
US6855830B2 (en) 2001-07-16 2005-02-15 Genzyme Corporation Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
ATE437639T1 (en) 2002-12-20 2009-08-15 Cancer Rec Tech Ltd 4-(1-(SULFONYL)-1H-INDOL-2-YL)-4-(HYDROXY)-CYCLOHEXA-2,5-DIENONE COMPOUNDS AND THEIR ANALOGUES AS THERAPEUTIC ACTIVE INGREDIENTS
US7153858B2 (en) * 2003-01-31 2006-12-26 Epix Delaware, Inc. Arylpiperazinyl compounds
US7276603B2 (en) 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
BR122018009866B8 (en) 2003-05-02 2021-07-27 Cardiome Pharma Corp methods for preparing aminocyclohexyl ether compounds and intermediate compounds
US7674820B2 (en) 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
CA2561819A1 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
WO2005097087A2 (en) 2004-04-01 2005-10-20 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
CA2586918C (en) 2004-11-08 2021-01-19 Cardiome Pharma Corp. Use of ion channel modulating compounds for treating acute atrial fibrillation in a human
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (en) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates.
TR201908314T4 (en) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutathione based drug delivery system.
IL295075A (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
PT3133070T (en) 2009-11-27 2019-11-11 Genzyme Corp Eliglustat (genz 112638) as inhibitor of glucosylceramide synthase for use in a method of treating fabry's or gaucher's disease, the method comprising adjusting the individual therapeutical dose to the p-450 metabolism of the patient
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

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US3965180A (en) * 1971-11-01 1976-06-22 The Upjohn Company 4'-Fluoro-4-{[4-(phenyl)-4-alkoxy-cyclo-hexyl]amino}butyrophenones and the salts thereof
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GR73633B (en) * 1980-03-10 1984-03-26 Janssen Pharmaceutica Nv
CA1280421C (en) * 1985-07-02 1991-02-19 Albert A. Carr 1,4-disubstituted piperidinyl derivatives
US5047406A (en) * 1989-12-06 1991-09-10 Warner-Lambert Co. Substituted cyclohexanols as central nervous system agents
US4975445A (en) * 1989-12-06 1990-12-04 Warner-Lambert Company Substituted cyclohexenes as central nervous system agents
US4957921A (en) * 1989-12-06 1990-09-18 Warner-Lambert Company Substituted cyclohexanols as central nervous system agents
CA2075057A1 (en) * 1990-03-15 1991-09-16 Pharmacia & Upjohn Company Llc Therapeutically useful heterocyclic indole compounds
US5036070A (en) * 1990-06-13 1991-07-30 American Home Products Corporation Polycyclic phenalkyl amines as psychotropic agents

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