RU74289U1 - DEVICE FOR CARRYING OUT EXPERIMENTS ON SMALL ANIMALS - Google Patents

Abstract

The utility model relates to biology and experimental medicine and is intended for conducting chronic experiments and long-term studies in small experimental animals.

The objective of the utility model is to expand the capabilities of the device for conducting long-term physiological studies on the caudal region of the spine in conditions close to natural in ontogenesis, and to increase the reliability of fixation of the studied animal.

This task is achieved by the fact that the device for conducting experiments on small animals, containing a base pivotally connected to it by a cover made narrowed to the place of its attachment to the base, equipped with a device for fixing the cover relative to the base with slots for manipulation and clamps, and the device is additionally equipped interchangeable table for manipulations on the caudal region of the spine with a latch installed therein, while at the base of the table slots are made for installing and moving the fix ator.

The animal thus fixed is suitable for the formulation and implementation of the necessary experiments. An animal in such a device can be for a long time. Reliable fixation of small animals of various ages and sizes is ensured. It is now possible to conduct experiments at various levels of the caudal spine simultaneously for a long time, that is, in ontogenesis. The device is simple in design, convenient in operation, reliable in operation.

Description

The utility model relates to biology and experimental medicine and is intended for conducting chronic experiments and long-term studies in small experimental animals.

A device for conducting experiments on small animals is known, comprising a base, a hinged lid pivotally connected to it with slots for manipulations, and clamps (A.S. 401356, MKI A61D 3/00, publ. 15.01.82, BI 2).

However, the known device does not allow for long-term physiological studies on the caudal region of the spine, close to natural, in ontogenesis.

The closest in technical essence and the achieved effect is a device for conducting experiments on small animals, containing a cover made narrowed to the point of its hinge attachment to the base, the opposite end of which is equipped with a device for fixing the position of the cover relative to the base, while on this section of the cover and the base is made several rows of coaxial retainers, and the latter are the core elements (A. S. 2212863, MKI 7 A61D 3/00, publ. 09/27/2003, BI 27). This device is taken as a prototype.

However, the known device does not allow for long-term physiological studies on the caudal region of the spine, close to natural, in ontogenesis.

The objective of the utility model is to expand the capabilities of the device for conducting long-term physiological studies on the caudal region of the spine in conditions close to natural in ontogenesis, and to increase the reliability of fixation of the studied animal.

This task is achieved by the fact that the device for conducting experiments on small animals, containing a base pivotally connected to it by a cover made narrowed to the place of its attachment to the base, equipped with a device for fixing the cover relative to the base with slots for manipulation and clamps, and the device is additionally equipped interchangeable table for manipulations on the caudal region of the spine with a latch installed therein, while at the base of the table slots are made for installing and moving the fix ator.

Figure 1 shows the device, side view; figure 2 is the same, a top view; figure 3 is the same front view; figure 4 - retainer of the caudal spine top view, figure 5 the same side view; 6 is a mobile screw with internal thread.

The device comprises a cover 1 with slots 2 and a groove for the paw 3, mounted on the base 4. The tapering end of the cover 1 with screws 5 is pivotally attached to the base 4. The opposite end of the cover 1 has a device for fixing the position of the cover relative to the base, made in the form of lateral transverse slots 6, coupled with fixing screws 7, mounted on the base 4. The depth of the slots 6 allows you to change the position of the cover 1 relative to the base 4 in height depending on the size of the animal (figure 1). In this section of the lid 1 from the input side of the device, as well as in the base 4, several rows of holes 8 (Fig. 2) for the rod elements 9 (Fig. 3) locking the animal are made. The table for manipulations on the tail section of the spine 10 (Fig. 4) is fixed in the hole 11 (Fig. 2) of the base 4 (Fig. 1) with a latch

tables for manipulations on the caudal region of the spine 12 (Fig. 5). The manipulation table on the caudal region of the spine 10 comprises retainers of the caudal region of the spine 13 (FIG. 4), which moves along the groove 14 and consists of a flexible coupling 15 (FIG. 4), a tension screw of the flexible coupling 16 with a washer 17 and a lock nut 18, and a movable screw with an internal thread 19 fixing this screw to the nut 20 (FIG. 6).

The device operates as follows. To fix the experimental animal, such as rats, the rod elements 9 are pulled out of the holes 8 in the device (FIG. 2, FIG. 3). The rat is placed in the device so that the animal’s head enters the tapering part of this device and wedges there between the lid 1 and the base 4 (Fig. 1). Then insert several rod elements 9 into the holes 8 (figure 2, figure 3) and lock the animal. After that, using the slots 6, the lid 1 is installed at a level relative to the base 4 so that the animal is pressed against the base 4, and this optimum position of the lid 1 is fixed with fixing screws 7 (Fig. 1). Between the rod elements 9 (Fig. 3), the tail section of the rat spine is brought out, laid on the manipulation table on the tail section of the spine 10 and the tail section of the rat spine is fixed with the tail section of the spine 13. The fixation is carried out using a flexible sleeve 15 (figure 4) and the tension screw 16 by moving the washer 17 connected to it by a flexible coupling 15 and a lock nut 18 (Fig.6). Depending on the size of the animal under study, a movable screw with an internal thread 19 (Fig. 6) is displaced along the groove 14 (Fig. 4) and attached to the table for manipulations on the tail section of the spine 10 (Fig. 4) with a nut 20 fixing this screw (Fig. 6). In this position, the animal appears to be securely fixed in the inventive device, and it is possible to conduct experiments at any level of the caudal spine of animals, as well as to study the reaction of tissues to damage, measure edema, local temperature,

to determine the size and make imprints of wounds, to study the processes of osteogenesis. In this case, the normal physiological state of the animal is not disturbed.

The animal thus fixed is suitable for setting up and conducting experiments on the tail section of the animal. An animal in such a device can be for a long time. Reliable fixation of small animals of various ages and sizes is ensured. It is now possible to conduct experiments at various levels of the caudal spine simultaneously for a long time, that is, in ontogenesis. The device is simple in design, convenient in operation, reliable in operation.

Claims (1)

A device for conducting experiments on small animals, comprising a base, a hinge connected to it, made narrowed to the place of its attachment to the base, equipped with a device for fixing the cover relative to the base with slots for manipulation and clamps, characterized in that the device is additionally equipped with a removable table for manipulations on the caudal region of the spine with a latch installed on it, with slots made at the base of the table for installing and moving the latch.