RU2796077C1 - Medical aerosol ozonizer - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention relates to medical technology, and can be used in clinical and experimental medicine, in particular surgery (including microsurgery) and physiotherapy, for combined drug and physiotherapy dosed effects on treated tissues through a combination of controlled aerosol spraying of medicinal liquids (due to changing the air flow rate and the supplied volume of the drug) and one-stage adjustable (due to changing the output ozone concentration over a wide range (for example, from 0 to 6.0 g/h in steps of 0.1 g/h)) ozonation of treated tissues, which increases the sensitivity of pathogens to drugs, improves the penetration of sprayed medicinal liquids into cells and can be used to prevent and treat infectious (in particular, resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as to achieve antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) both in a hospital and in combat and emergency situations.

EFFECT: using medical aerosol ozonizer.

1 cl, 2 dwg

Description

The invention relates to the field of medicine, namely to medical technology, and can be used in clinical and experimental medicine, in particular surgery (including microsurgery) and physiotherapy for combined drug-physiotherapeutic dosed effects on treated tissues due to a combination of adjustable (due to changing air flow rate and the supplied volume of the medicinal product) aerosol spraying of medicinal liquids and one-stage controlled (by changing the output ozone concentration over a wide range (for example, from 0 to 6.0 g/hour in steps of 0.1 g/hour) ozonation of treated tissues , which increases the sensitivity of pathogens to drugs, improves the penetration of sprayed medicinal liquids into cells and can be used to prevent and treat infectious (in particular, resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as for achievement of antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) both in a hospital and in combat and emergency situations.

To date, to solve such problems in medicine, analogues are used that are mainly intended for ozonizing liquids or blowing tissue surfaces with an ozone-oxygen or ozone-air mixture. Their design features do not provide for and do not allow simultaneous spraying of the drug and ozonation of the treated tissues. In addition, relatively bulky dimensions reduce the mobility of these devices, and their consumption of power mainly from the household power supply excludes the possibility of using them in combat and emergency situations. At the same time, the absence in the set of existing analogues of not only an ergonomic mini-nebulizer, but even a simple nebulizer excludes the possibility of using these devices both in surgery and in microsurgery. At the same time, the lack of the possibility of dosing the output ozone concentration and air flow rate completely excludes the possibility of using the device for such scientific purposes as determining the minimum and maximum therapeutic ozone concentrations or characterizing its destructive effect when a toxic concentration is reached when exposed to various tissues (skin, mucous membranes, nervous tissue, muscle tissue, etc.) or organs, which is of decisive importance in the development of new methods of ozone exposure for the treatment of patients with various, mainly infectious, pathologies of organs and tissues.

Thus, at present, there is no device for use in either clinical or experimental medicine, which makes it possible to combine and dose the treated tissues through their simultaneous controlled ozonation and aerosol spraying of medicinal liquids, as part of the prevention and treatment of infectious (in particular resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as to achieve antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) both in a hospital and in combat and emergency conditions. situations.

One of the analogues of the proposed invention is a portable autonomous device for generating ozone (RF patent No. 2699265, IPC F24F 3/16, С01В 13/11, publ. 2019.09.04), containing an ozone-resistant housing, a fan, a switch, a serial pulse generator, a high-voltage pulse converter , thermal protection, a battery with a boost converter, an air filter, an air dryer and a reactor chamber, which ensures a stable level of ozone production in conditions of high humidity and / or dust. Thus, this device belongs to autonomous ozone generation devices, but it is focused only on the disinfection and deodorization of small premises, warehouses and storage facilities for agricultural purposes and is not a medical device.

The described shortcomings are partially eliminated in another analogue of the proposed medical aerosol ozonizer: a portable ozonator with an ozone destructor (RF patent No. 45272, IPC A61L 9/015, publ. 2005.05.10), which is a medical device designed for the prevention and treatment of various diseases, as well as deodorization and disinfection of air in various rooms. However, its main disadvantages are the lack of autonomy (there is no provision for battery operation), the impossibility of combined action on the treated tissues by simultaneous ozonation and aerosol spraying of medicinal liquids, as well as the absence of an ozone tip (working pen), which completely excludes the possibility of using the device for local processing of human tissues (or experimental animals) as part of the prevention and treatment of infectious (in particular, those resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as to achieve antihypoxic, anti-inflammatory and regenerative effects.

The closest analogue of the proposed medical aerosol ozonizer is a reversible gasifier (RF patent No. 2532502, IPC A61M 31/00, publ. 2014.11.10), which was chosen as a prototype of the proposed invention. This device belongs to medical equipment and structurally has a tip in the form of an ozone pen, due to which it can be used in surgery, namely in the field of surgery, postoperative and other wounds, as well as soft tissues and mucous membranes in order to stop bleeding, prevent and treatment of purulent complications, infectious and dermatological diseases.

The main disadvantages of the prototype are as follows:

1. There is no technical possibility of a combined effect on the treated tissues by their simultaneous ozonation and aerosol spraying of medicinal liquids;

2. There is no technical possibility of aerosol spraying of medicinal liquids;

3. There is no technical possibility of adjusting the parameters of aerosol spraying of medicinal liquids (air flow rate, volume of drug supplied);

4. The relatively bulky design of the ozone pen is not adapted and not intended for use in microsurgery;

5. There is no technical possibility of adjusting the power of ozone exposure (the air flow regulator is not provided and it is structurally impossible to adjust the output concentration of ozone);

6. Possibility of dosing exposure to ozone exposure is not provided;

7. Powered by household power only.

The technical result of the invention is the use of a medical aerosol ozonator in clinical and experimental surgery, physiotherapy and microsurgery for a combined drug-physiotherapeutic dosed effect on the treated tissues due to a combination of adjustable (due to changes in the air flow rate and the volume of the drug supplied) aerosol spray of medicinal liquids and simultaneous controlled ozonation (by changing the output concentration of ozone in the ozone-oxygen or ozone-air mixture) of treated tissues, which increases the sensitivity of pathogens to drugs, improves the penetration of sprayed medicinal liquids into cells and can be used to prevent and treat infectious (in particular resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as to achieve antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) both in a hospital and in combat and emergency conditions. situations.

The solution to this problem is ensured by the fact that in a medical aerosol ozonator, consisting of a device body, a power cable with grounding, an air flow adjustment pedal, a set of sprayers and a connecting tube, an inlet fitting equipped with a filter and a protective cap, internal air hoses, an air compressor, a generator ozone generator, consisting of a high-voltage generator and gas discharge tubes with different parameters of the ozone output concentration or an ozone generator that allows you to adjust the output concentration using a rheostat with one ozone gas discharge tube, an ozone-resistant internal ozone hose, an outlet fitting with an air valve, a built-in battery, and also a control and adjustment unit, which includes a control board, a display showing the operating time, ozone concentration and the operating mode of the device, buttons for starting and stopping work, entering the operating time and selecting the operating mode (ozone-air), knobs for adjusting the output ozone concentration and airflow rate, as well as the ozone output concentration sensor are located directly in the device body, the airflow rate adjustment pedal is a peripheral element of the control and adjustment unit, which duplicates the functions of the airflow rate adjustment knob, the operation start-stop button and the operation mode button (ozone - air), an ergonomic mini-nebulizer has optimal weight and size parameters adapted for use in microsurgery and structurally includes a reservoir for a medicinal device and a set of replaceable nozzles, a skin nebulizer structurally includes an optimal volume of a reservoir for a medicinal product and a set of replaceable nozzles, and the connecting tube is made in the form twisted PVC air hose.

The technical result of the invention is achieved due to the fact that the medical aerosol ozonizer, which is a portable autonomous medical device, powered both from a household electrical network and from a direct current source (battery with a voltage of 12 volts), structurally adapted for use in a clinical setting. and experimental surgery, physiotherapy and microsurgery for the purpose of combined (ozonation and drug spraying) drug-physiotherapeutic dosed effects on treated tissues by combining controlled (by changing the air flow rate and the supplied volume of the drug) aerosol spraying of medicinal liquids and one-stage controlled (for by changing the output concentration of ozone in the ozone-oxygen or ozone-air mixture) ozonation of treated human tissues (or experimental animals) both in a hospital and in combat and emergency situations due to the fact that the main electronic components, battery, air line (inlet fitting, internal air hose No. 1, internal air hose No. 2 and air compressor) and ozone line (ozone discharge tubes with different parameters of ozone output concentration or one ozone gas discharge tube, which is part of an ozone generator equipped with a rheostat, resistant to ozone an internal ozone hose with an ozone output concentration sensor and an outlet fitting with an air valve), as well as the controls are located in the compact body of the device, and the design includes an ergonomic mini-nebulizer with a reservoir for the drug device and a set of interchangeable nozzles, which has optimal weight and size parameters, adapted to perform precision combined exposure (ozonation and drug spraying), a skin sprayer with an optimal volume of the drug reservoir and a set of replaceable nozzles, a connecting tube made in the form of a twisted PVC air hose and an air flow rate adjustment pedal, which is a peripheral element of the control unit and adjustment of the duplicating functions of the air flow rate adjustment knob, the start-end button and the operation mode button (ozone-air).

The invention is illustrated in FIG. 1, which schematically shows the external device of a medical aerosol ozonizer, FIG. 2, which shows a schematic diagram of its internal structure.

The medical aerosol ozonizer is schematically shown in Fig. 1 and in FIG. 2 and consists of the body of the device (1), power cable with grounding (2), pedal for adjusting the air flow rate (3), a set of nozzles (4) and a connecting tube (5). At the same time, the inlet fitting (6) equipped with a filter (7) and a protective cap (8), internal air hose No. 1 (9), internal air hose No. 2 (10), air compressor (11), ozone generator (12a), consisting of a high-voltage generator (13) and ozone gas discharge tubes with different parameters of the output ozone concentration (14a) or an ozone generator that allows you to adjust the output concentration using a rheostat (12b) with one ozone gas discharge tube equipped with a radiator (14b), ozone-resistant internal ozone a hose equipped with an ozone concentration sensor (15), an outlet fitting with an air valve (16), a built-in rechargeable battery (17), as well as a control and adjustment unit that includes a control board (18), a display (19) showing the operating time , ozone concentration and operating mode of the device, start-stop operation button (20), operation time entry buttons (21) and operation mode selection button (ozone-air) (22), ozone output concentration adjustment knob (23) and speed adjustment knob air flow (24) are placed directly in the device body (1). The airflow rate adjustment pedal (3) is a peripheral element of the control and adjustment unit, which duplicates the functions of the airflow rate adjustment knob (24), the operation start-stop button (20) and the operation mode button (ozone-air) (22). A set of nebulizers (4) is represented by an ergonomic mini-nebulizer (25), which has optimal weight and size parameters adapted for use in microsurgery, and structurally includes a small reservoir for the drug and a set of replaceable mini-nozzles, as well as a skin nebulizer (26), which structurally includes an optimal volume reservoir for the drug and a set of replacement nozzles. At the same time, the connecting tube (5) connecting the atomizers (25 and 26) with the outlet fitting with the air valve (16) is made in the form of a twisted PVC air hose.

The principle of operation of a medical aerosol ozonizer is as follows. With the help of the start-stop button of the device, the operation of the air compressor is activated, the power of which is regulated using the air flow rate adjustment knob and the duplicate air flow rate control pedal, as a result of which a negative pressure is created in the internal air hose No. 1, which leads to the supply of filtered atmospheric air or sterile oxygen (supplied from a connected cylinder) through an inlet fitting equipped with a filter and a protective cap into the internal air hose No. 2, branched and connected to 7 ozone gas discharge tubes with different parameters of the output ozone concentration (1 tube - 0, 1 g/hour (tube No. 1), 2 tubes - 0.2 g/hour (tubes No. 2 and 3), 1 tube - 0.5 g/hour (tube No. 4), 2 tubes - 1.0 g/hour hour (tubes No. 5 and 6) and 1 tube - 3.0 g / hour (tube No. 7), or connected to one ozone gas discharge tube, which is an element of an ozone generator equipped with a rheostat, powered by a high-voltage generator driven by selection buttons operating mode (ozone-air), after which the resulting (ozone-air / ozone-oxygen) ozone mixture or unchanged (air / oxygen) flow through the internal ozone hose through the outlet fitting with an air valve enters the connecting tube, made in the form of a twisted air hose made of polyvinyl chloride, connected to an ergonomic mini-nebulizer or skin nebulizer, where the drug is sprayed from the tanks included in the nebulizers (drug depot) under pressure created by the operation of an air compressor in the ozone line (internal ozone hose, outlet fitting with air valve and connecting tube), the excess of which is leveled by the operation of the air valve mounted in the outlet fitting. At the same time, the adjustment of the output ozone concentration (from 0 to 6.0 g/h in increments of 0.1 g/h) is carried out under the control of the sensor of the output ozone concentration and due to the operation of the ozone generator with the ability to adjust the output ozone concentration using a rheostat with one ozone gas discharge tube or combined operation of 7 ozone gas discharge tubes (see Table No. 1). For example, to obtain an output concentration of ozone equal to 0.1 g / h, the operation of the ozone gas discharge tube No. 1 is started, 0.2 g / h - the operation of the ozone gas discharge tube No. 2 or No. 3, 0.3 g / h - the simultaneous operation of ozone gas discharge tubes tubes No. 1 and No. 2 or No. 1 and No. 3, 0.4 g / h - simultaneous operation of ozone gas discharge tubes No. 2 and No. 3, 0.5 g / h - operation of ozone gas discharge tube No. 4 or simultaneous operation of ozone gas discharge tubes No. 1, 2 and 3, 0.6 g/h - simultaneous operation of ozone gas discharge tubes No. 1 and No. 4, 0.7 g/h - simultaneous operation of ozone gas discharge tubes No. 2 and No. 4 or No. 3 and No. 4, 0 .8 g/h - simultaneous operation of ozone gas discharge tubes No. 1, No. 2 and No. 4 or No. 1, No. 3 and No. 4, 0.9 g/h - simultaneous operation of ozone gas discharge tubes No. 2, No. 3 and No. 4, 1.0 g/hour - operation of the ozone discharge tube No. 5 or No. 6 or simultaneous operation of the ozone gas discharge tubes No. 1, No. 2, No. 3 and No. 4, and so on by analogy until a concentration of 6.0 g/hour is reached. If it is necessary to increase the maximum calculated output concentration of ozone, the medical aerosol ozonizer can be equipped with additional ozone discharge tubes.

Thus, a medical aerosol ozonizer can fundamentally operate in both combined (air/ozone and irrigation) and isolated (air or ozone or irrigation) dosed effects on treated tissues, makes it possible to perform controlled aerosol spraying of medicinal liquids (by changing the speed air flow and the volume of the supplied drug, and one-stage controlled ozonation (by changing the output concentration of ozone over a wide range, for example, from 0 to 6.0 g/hour in increments of 0.1 g/hour.

That is why, using a medical aerosol ozonizer in clinical or experimental medicine, it is possible to combine and dose the treated tissues through their simultaneous controlled ozonation and aerosol spraying of medicinal liquids, as part of the prevention and treatment of infectious diseases (in particular, those resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, which increases the sensitivity of pathogens to drugs, improves the penetration of sprayed medicinal liquids into cells and can be used to achieve antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) as in a hospital as well as in combat and emergency situations.

Distinctive features that provide the advantage of a medical aerosol ozonator over analogues are as follows:

1. The device is structurally adapted and intended for use in microsurgery;

2. Structurally, the working part is made in the form of an ergonomic mini-nebulizer with optimal weight and size parameters for use in microsurgery;

3. Due to the presence of foot control by means of a pedal, the speed and dynamism of the impact on the treated tissues increases without reducing the precision of manipulations, which is also optimal for microsurgery;

4. By changing the air flow rate and the volume of the supplied drug, it is technically possible to adjust the parameters of spraying medicinal liquids;

5. Due to the presence of an ozone generator in the device with the ability to adjust the output ozone concentration using a rheostat with one ozone gas discharge tube or the presence of at least 7 ozone gas discharge tubes with different parameters of the output ozone concentration and their combined or isolated inclusion in operation (according to table No. 1) it is structurally possible to adjust the output concentration of ozone over a wide range (for example, from 0 to 6.0 g/hour in increments of 0.1 g/hour);

6. There is a technical possibility of a combined effect on the treated tissues by their simultaneous ozonation and aerosol spraying of medicinal liquids;

7. It is possible to automatically calibrate the output concentration of ozone due to the presence of an ozone concentration sensor, which, in combination with a control unit, regulates the operation of the ozone generator;

8. Due to the technical possibility of adjusting the air flow rate, the volume of the supplied drug, as well as the output concentration of ozone, it is possible to select the most effective parameters for influencing various tissues (skin, mucous membranes, nervous tissue, muscle tissue, and so on) or organs, which plays of decisive importance in the development of new methods of ozone exposure in the treatment of patients with various, mainly infectious, pathologies of organs and tissues.

9. The presence of a timer as part of the control board determines the possibility of dosing exposure to ozone exposure;

10. It is powered by a built-in 12 volt battery, which allows you to use not only power from a household power supply and makes the medical aerosol ozonizer as mobile as possible, allowing you to use it both in clinical and experimental medicine, including surgery, microsurgery or physiotherapy. only in stationary conditions, but also in combat and emergency situations.

All this makes it possible to use a medical aerosol ozonizer in clinical and experimental medicine for a combined drug-physiotherapeutic effect on treated tissues due to the combination of aerosol spraying of medicinal liquids and simultaneous ozonation of treated tissues, which not only increases the sensitivity of pathogens to drugs, but also improves the penetration of sprayed medicinal products. liquids into cells and can be used to prevent and treat infectious (in particular, resistant to modern antibacterial drugs and disinfectants) lesions of the skin, mucous membranes, wound surfaces or cavities, as well as to achieve antihypoxic, anti-inflammatory and regenerative effects on treated human tissues (or experimental animals) both in a hospital and in combat and emergency situations.

The conducted experimental studies have shown the multilateral functionality, as well as the ease of use of the proposed invention, which for the first time demonstrates the possibility and effectiveness of the combined drug-physiotherapeutic effect on the treated tissues due to the combination of aerosol spraying of medicinal liquids and simultaneous ozonation of the treated tissues, the possibility of using the proposed medical aerosol ozonizer in microsurgery, as well as the ability to adjust the output concentration of ozone over a wide range (for example, from 0 to 6.0 g / h in increments of 0.1 g / h), thanks to the first applied technical solution in the form of combined or isolated work (according to table No. 1 ) at least 7 ozone gas discharge tubes with different parameters of the output ozone concentration.

Claims (1)

Medical aerosol ozonizer, consisting of a device body, a grounded power cable, an air flow rate adjustment pedal, a set of sprayers and a connecting tube, characterized in that it contains an inlet fitting equipped with a filter and a protective cap, internal air hoses, an air compressor, an ozone generator, consisting of a high-voltage generator and gas discharge tubes with different parameters of ozone output concentration, an ozone-resistant internal ozone hose equipped with an ozone concentration sensor, an outlet fitting with an air valve, a built-in battery, as well as a control and regulation unit, including a board control, a display capable of displaying the operating time, ozone concentration and the operating mode of the ozone-air device, the knobs for adjusting the output ozone concentration and air flow rate are located directly in the device case, while the air flow rate adjustment pedal is a peripheral element of the control and adjustment unit and is made with the possibility of duplicating the functions of the air flow rate adjustment knob, the start-stop button and the ozone-air mode button, in addition, the nebulizer has weight and size parameters adapted for use in microsurgery, and includes a reservoir for the drug and a set of replaceable nozzles, and the skin nebulizer includes the volume of the drug reservoir and a set of replaceable nozzles, while the connecting tube, configured to connect the nebulizers to the outlet fitting with an air valve, is made in the form of a twisted PVC air hose.

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