RU2709198C2 - Применение изоксазолиновых соединений для лечения демодекоза - Google Patents
Применение изоксазолиновых соединений для лечения демодекоза Download PDFInfo
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- RU2709198C2 RU2709198C2 RU2017126029A RU2017126029A RU2709198C2 RU 2709198 C2 RU2709198 C2 RU 2709198C2 RU 2017126029 A RU2017126029 A RU 2017126029A RU 2017126029 A RU2017126029 A RU 2017126029A RU 2709198 C2 RU2709198 C2 RU 2709198C2
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- isoxazoline compound
- treatment
- formula
- dogs
- mammal
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Classifications
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- A—HUMAN NECESSITIES
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
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| EP14199562 | 2014-12-22 | ||
| EP14199562.1 | 2014-12-22 | ||
| PCT/EP2015/080744 WO2016102437A1 (en) | 2014-12-22 | 2015-12-21 | Use of isoxazoline compounds for treating demodicosis |
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| RU2017126029A RU2017126029A (ru) | 2019-01-24 |
| RU2017126029A3 RU2017126029A3 (enExample) | 2019-06-20 |
| RU2709198C2 true RU2709198C2 (ru) | 2019-12-17 |
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| RU2017126029A RU2709198C2 (ru) | 2014-12-22 | 2015-12-21 | Применение изоксазолиновых соединений для лечения демодекоза |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| PL3236960T3 (pl) | 2014-12-22 | 2025-07-07 | Intervet International B.V. | Fluralaner do zastosowania w leczeniu demodekozy |
| WO2018039508A1 (en) * | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| CN107501199A (zh) * | 2017-08-16 | 2017-12-22 | 南京农业大学 | 氟雷拉纳单体化合物的提取和纯化方法 |
| KR20250057155A (ko) * | 2017-12-15 | 2025-04-28 | 타르서스 파마수티칼스, 아이엔씨. | 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법 |
| US11880349B2 (en) | 2019-04-30 | 2024-01-23 | Salesforce, Inc. | System or method to query or search a metadata driven distributed ledger or blockchain |
| WO2022020585A1 (en) | 2020-07-24 | 2022-01-27 | Elanco Us Inc. | Process for making an isoxazoline compound and intermediate thereof |
| CN115785017B (zh) * | 2022-12-06 | 2023-12-08 | 海利尔药业集团股份有限公司 | 一种取代的苯酰胺异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2067863C1 (ru) * | 1994-05-25 | 1996-10-20 | Казанский государственный технологический университет | Акарицидный состав для лечения чесотки домашних животных |
| WO2009024541A2 (en) * | 2007-08-17 | 2009-02-26 | Intervet International B.V. | Isoxazoline compositions and their use as antiparasitics |
| WO2010070068A2 (en) * | 2008-12-19 | 2010-06-24 | Novartis Ag | Organic compounds |
| US20130065846A1 (en) * | 2011-09-12 | 2013-03-14 | Mark D. Soll | Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof |
| US20130203692A1 (en) * | 2012-02-06 | 2013-08-08 | Merial Limited | Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS53639B1 (sr) | 2004-03-05 | 2015-04-30 | Nissan Chemical Industries Ltd. | Izoksazolinom supstituisano benzamidno jedinjenje i sredstvo za kontrolu štetnih organizama |
| DE102004053964A1 (de) * | 2004-11-09 | 2006-05-11 | Bayer Healthcare Ag | Mittel gegen Demodikose |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| HUE037127T2 (hu) | 2007-06-27 | 2018-08-28 | Du Pont | Állati károkozó irtására szolgáló eljárás |
| TWI411395B (zh) | 2007-12-24 | 2013-10-11 | Syngenta Participations Ag | 殺蟲化合物 |
| US8377942B2 (en) | 2008-12-18 | 2013-02-19 | Novartis Ag | Isoxazolines derivatives and their use as pesticide |
| EP2658541B2 (en) | 2010-12-27 | 2025-12-17 | Intervet International B.V. | Topical localized isoxazoline formulation comprising glycofurol |
| CN103260621B (zh) | 2010-12-27 | 2016-08-24 | 英特维特国际股份有限公司 | 外用局部异噁唑啉制剂 |
| ES2585555T3 (es) | 2011-03-10 | 2016-10-06 | Zoetis Services Llc | Derivados espirocíclicos de isoxazolina como agentes antiparasitarios |
| AU2013245011B2 (en) | 2012-04-04 | 2017-11-23 | Intervet International B.V. | Solid oral pharmaceutical compositions for isoxazoline compounds |
| WO2014090918A1 (en) * | 2012-12-13 | 2014-06-19 | Novartis Ag | Process for the enantiomeric enrichment of diaryloxazoline derivatives |
| CN110327468B (zh) | 2013-12-20 | 2023-04-28 | 英特维特国际股份有限公司 | 异噁唑啉组合物及其在预防或治疗动物的寄生虫侵袭中的用途 |
| PL3236960T3 (pl) | 2014-12-22 | 2025-07-07 | Intervet International B.V. | Fluralaner do zastosowania w leczeniu demodekozy |
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2015
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- 2015-12-21 US US15/537,547 patent/US20170348286A1/en not_active Abandoned
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- 2015-12-21 AU AU2015371175A patent/AU2015371175B2/en active Active
- 2015-12-21 CN CN202210404756.7A patent/CN114681453A/zh active Pending
- 2015-12-21 BR BR112017013286-9A patent/BR112017013286A2/pt not_active Application Discontinuation
- 2015-12-21 DK DK21213190.8T patent/DK4008329T3/da active
- 2015-12-21 PT PT212131908T patent/PT4008329T/pt unknown
- 2015-12-21 EP EP15817303.9A patent/EP3236960B1/en active Active
- 2015-12-21 ES ES21213190T patent/ES3037078T3/es active Active
- 2015-12-21 ES ES15817303T patent/ES3018234T3/es active Active
- 2015-12-21 CN CN201580069964.4A patent/CN106999475B/zh active Active
- 2015-12-21 FI FIEP15817303.9T patent/FI3236960T3/fi active
- 2015-12-21 EP EP25179725.4A patent/EP4599830A3/en active Pending
- 2015-12-21 EP EP21213190.8A patent/EP4008329B1/en active Active
- 2015-12-21 PT PT158173039T patent/PT3236960T/pt unknown
- 2015-12-21 FI FIEP21213190.8T patent/FI4008329T3/fi active
- 2015-12-21 WO PCT/EP2015/080744 patent/WO2016102437A1/en not_active Ceased
- 2015-12-21 JP JP2017533378A patent/JP6706262B2/ja active Active
- 2015-12-21 RU RU2017126029A patent/RU2709198C2/ru active
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2018
- 2018-04-04 US US15/944,967 patent/US10799483B2/en active Active
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2020
- 2020-09-09 US US17/015,263 patent/US20200405692A1/en not_active Abandoned
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2021
- 2021-06-04 AU AU2021203686A patent/AU2021203686A1/en not_active Abandoned
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2023
- 2023-08-25 AU AU2023219972A patent/AU2023219972B2/en active Active
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