RU2705375C2 - Фармацевтические композиции, содержащие антибактериальные агенты - Google Patents
Фармацевтические композиции, содержащие антибактериальные агенты Download PDFInfo
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- RU2705375C2 RU2705375C2 RU2017110457A RU2017110457A RU2705375C2 RU 2705375 C2 RU2705375 C2 RU 2705375C2 RU 2017110457 A RU2017110457 A RU 2017110457A RU 2017110457 A RU2017110457 A RU 2017110457A RU 2705375 C2 RU2705375 C2 RU 2705375C2
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- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- ertapenem
- formula
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- JTHRRMFZHSDGNJ-UHFFFAOYSA-N piperazine-2,3-dione Chemical compound O=C1NCCNC1=O JTHRRMFZHSDGNJ-UHFFFAOYSA-N 0.000 description 1
- 125000005575 polycyclic aromatic hydrocarbon group Chemical group 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical group C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- ILJOYZVVZZFIKA-UHFFFAOYSA-M sodium;1,1-dioxo-1,2-benzothiazol-3-olate;hydrate Chemical compound O.[Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 ILJOYZVVZZFIKA-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- BRNULMACUQOKMR-UHFFFAOYSA-N thiomorpholine Chemical compound C1CSCCN1 BRNULMACUQOKMR-UHFFFAOYSA-N 0.000 description 1
- 229930192474 thiophene Chemical group 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 239000006150 trypticase soy agar Substances 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 150000003952 β-lactams Chemical group 0.000 description 1
- 229940126085 β‑Lactamase Inhibitor Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN193/MUM/2014 | 2014-01-21 | ||
| PCT/IB2015/050421 WO2015110950A1 (en) | 2014-01-21 | 2015-01-20 | Pharmaceutical compositions comprising antibacterial agents |
| IN193MU2014 IN2014MU00193A (enExample) | 2014-01-21 | 2015-01-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017110457A3 RU2017110457A3 (enExample) | 2018-10-03 |
| RU2017110457A RU2017110457A (ru) | 2018-10-03 |
| RU2705375C2 true RU2705375C2 (ru) | 2019-11-07 |
Family
ID=52629621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017110457A RU2705375C2 (ru) | 2014-01-21 | 2015-01-20 | Фармацевтические композиции, содержащие антибактериальные агенты |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10322116B2 (enExample) |
| EP (1) | EP3217979B8 (enExample) |
| AU (2) | AU2015208830A1 (enExample) |
| CA (1) | CA2954553C (enExample) |
| ES (1) | ES2804500T3 (enExample) |
| IN (1) | IN2014MU00193A (enExample) |
| NZ (1) | NZ728036A (enExample) |
| RU (1) | RU2705375C2 (enExample) |
| WO (1) | WO2015110950A1 (enExample) |
| ZA (1) | ZA201700064B (enExample) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100278921A1 (en) * | 2009-04-30 | 2010-11-04 | Fischer Cristina M | Solid oral formulation of abt-263 |
| WO2013030733A1 (en) * | 2011-08-27 | 2013-03-07 | Wockhardt Limited | 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections |
| RU2509560C1 (ru) * | 2013-03-22 | 2014-03-20 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Новые терапевтические комбинации миртазапина для применения при болевых расстройствах |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8796257B2 (en) * | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| MX366948B (es) * | 2012-05-30 | 2019-07-30 | Meiji Seika Pharma Co Ltd | Nuevo inhibidor de beta-lactamasa y proceso para prepararlo. |
| KR20150089086A (ko) * | 2013-01-14 | 2015-08-04 | 욱크하르트 리미티드 | 박테리아 감염을 치료하기 위한 조성물 및 방법 |
-
2015
- 2015-01-20 IN IN193MU2014 patent/IN2014MU00193A/en unknown
- 2015-01-20 WO PCT/IB2015/050421 patent/WO2015110950A1/en not_active Ceased
- 2015-01-20 AU AU2015208830A patent/AU2015208830A1/en not_active Abandoned
- 2015-01-20 CA CA2954553A patent/CA2954553C/en active Active
- 2015-01-20 ES ES15708275T patent/ES2804500T3/es active Active
- 2015-01-20 NZ NZ728036A patent/NZ728036A/en not_active IP Right Cessation
- 2015-01-20 EP EP15708275.1A patent/EP3217979B8/en active Active
- 2015-01-20 US US15/323,631 patent/US10322116B2/en active Active
- 2015-01-20 RU RU2017110457A patent/RU2705375C2/ru active
-
2017
- 2017-01-04 ZA ZA2017/00064A patent/ZA201700064B/en unknown
- 2017-12-19 US US15/846,929 patent/US20180104224A1/en not_active Abandoned
-
2020
- 2020-03-18 AU AU2020201956A patent/AU2020201956B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100278921A1 (en) * | 2009-04-30 | 2010-11-04 | Fischer Cristina M | Solid oral formulation of abt-263 |
| WO2013030733A1 (en) * | 2011-08-27 | 2013-03-07 | Wockhardt Limited | 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections |
| RU2509560C1 (ru) * | 2013-03-22 | 2014-03-20 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Новые терапевтические комбинации миртазапина для применения при болевых расстройствах |
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014MU00193A (enExample) | 2015-08-28 |
| RU2017110457A3 (enExample) | 2018-10-03 |
| AU2020201956B2 (en) | 2020-07-09 |
| BR112017003444A2 (pt) | 2023-03-07 |
| EP3217979B8 (en) | 2020-06-03 |
| CA2954553C (en) | 2022-12-06 |
| US10322116B2 (en) | 2019-06-18 |
| RU2017110457A (ru) | 2018-10-03 |
| EP3217979A1 (en) | 2017-09-20 |
| EP3217979B1 (en) | 2020-04-08 |
| US20180104224A1 (en) | 2018-04-19 |
| WO2015110950A1 (en) | 2015-07-30 |
| US20170202813A1 (en) | 2017-07-20 |
| NZ728036A (en) | 2019-12-20 |
| ES2804500T3 (es) | 2021-02-08 |
| CA2954553A1 (en) | 2015-07-30 |
| AU2020201956A1 (en) | 2020-04-02 |
| ZA201700064B (en) | 2018-08-29 |
| AU2015208830A1 (en) | 2017-04-27 |
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