RU2666590C2 - Мундштук для точного обнаружения выдыхаемого no - Google Patents
Мундштук для точного обнаружения выдыхаемого no Download PDFInfo
- Publication number
- RU2666590C2 RU2666590C2 RU2015115962A RU2015115962A RU2666590C2 RU 2666590 C2 RU2666590 C2 RU 2666590C2 RU 2015115962 A RU2015115962 A RU 2015115962A RU 2015115962 A RU2015115962 A RU 2015115962A RU 2666590 C2 RU2666590 C2 RU 2666590C2
- Authority
- RU
- Russia
- Prior art keywords
- oxidizing
- filter
- mouthpiece
- outlet
- sodium
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title description 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims abstract description 48
- 238000000034 method Methods 0.000 claims abstract description 30
- 230000001590 oxidative effect Effects 0.000 claims abstract description 26
- 239000002245 particle Substances 0.000 claims abstract description 22
- 238000005259 measurement Methods 0.000 claims abstract description 16
- 239000000126 substance Substances 0.000 claims abstract description 9
- JYLNVJYYQQXNEK-UHFFFAOYSA-N 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(CN)C1=CC=C(Cl)C=C1 JYLNVJYYQQXNEK-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims abstract description 6
- 239000000758 substrate Substances 0.000 claims abstract description 6
- 238000009530 blood pressure measurement Methods 0.000 claims abstract 5
- LEHBURLTIWGHEM-UHFFFAOYSA-N pyridinium chlorochromate Chemical compound [O-][Cr](Cl)(=O)=O.C1=CC=[NH+]C=C1 LEHBURLTIWGHEM-UHFFFAOYSA-N 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 9
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 7
- 150000001875 compounds Chemical class 0.000 claims description 7
- 239000002274 desiccant Substances 0.000 claims description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- XTEGARKTQYYJKE-UHFFFAOYSA-M Chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 claims description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 6
- 239000000460 chlorine Substances 0.000 claims description 6
- AMXOYNBUYSYVKV-UHFFFAOYSA-M lithium bromide Chemical compound [Li+].[Br-] AMXOYNBUYSYVKV-UHFFFAOYSA-M 0.000 claims description 6
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims description 6
- 239000007800 oxidant agent Substances 0.000 claims description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 5
- 230000003647 oxidation Effects 0.000 claims description 5
- 238000007254 oxidation reaction Methods 0.000 claims description 5
- 229910052760 oxygen Inorganic materials 0.000 claims description 5
- 239000001301 oxygen Substances 0.000 claims description 5
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 5
- BZSXEZOLBIJVQK-UHFFFAOYSA-N 2-methylsulfonylbenzoic acid Chemical compound CS(=O)(=O)C1=CC=CC=C1C(O)=O BZSXEZOLBIJVQK-UHFFFAOYSA-N 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- MPCRDALPQLDDFX-UHFFFAOYSA-L Magnesium perchlorate Chemical compound [Mg+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O MPCRDALPQLDDFX-UHFFFAOYSA-L 0.000 claims description 3
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 3
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 3
- 239000000440 bentonite Substances 0.000 claims description 3
- 229910000278 bentonite Inorganic materials 0.000 claims description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 3
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 claims description 3
- 239000012965 benzophenone Substances 0.000 claims description 3
- 239000007844 bleaching agent Substances 0.000 claims description 3
- 239000001110 calcium chloride Substances 0.000 claims description 3
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 3
- 229910052801 chlorine Inorganic materials 0.000 claims description 3
- 229910001919 chlorite Inorganic materials 0.000 claims description 3
- 229910052619 chlorite group Inorganic materials 0.000 claims description 3
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims description 3
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 claims description 3
- 229940117975 chromium trioxide Drugs 0.000 claims description 3
- WGLPBDUCMAPZCE-UHFFFAOYSA-N chromium trioxide Inorganic materials O=[Cr](=O)=O WGLPBDUCMAPZCE-UHFFFAOYSA-N 0.000 claims description 3
- JOPOVCBBYLSVDA-UHFFFAOYSA-N chromium(6+) Chemical class [Cr+6] JOPOVCBBYLSVDA-UHFFFAOYSA-N 0.000 claims description 3
- GAMDZJFZMJECOS-UHFFFAOYSA-N chromium(6+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[Cr+6] GAMDZJFZMJECOS-UHFFFAOYSA-N 0.000 claims description 3
- 239000004927 clay Substances 0.000 claims description 3
- 229910052570 clay Inorganic materials 0.000 claims description 3
- GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 claims description 3
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 3
- 229910000366 copper(II) sulfate Inorganic materials 0.000 claims description 3
- SOCTUWSJJQCPFX-UHFFFAOYSA-N dichromate(2-) Chemical class [O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O SOCTUWSJJQCPFX-UHFFFAOYSA-N 0.000 claims description 3
- 229910052731 fluorine Inorganic materials 0.000 claims description 3
- 239000011737 fluorine Substances 0.000 claims description 3
- 229910052736 halogen Inorganic materials 0.000 claims description 3
- 150000002366 halogen compounds Chemical class 0.000 claims description 3
- 150000002367 halogens Chemical class 0.000 claims description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 3
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 3
- 239000002808 molecular sieve Substances 0.000 claims description 3
- 150000002823 nitrates Chemical class 0.000 claims description 3
- 229910017604 nitric acid Inorganic materials 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 239000012285 osmium tetroxide Substances 0.000 claims description 3
- 229910000489 osmium tetroxide Inorganic materials 0.000 claims description 3
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 claims description 3
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 claims description 3
- 150000002978 peroxides Chemical class 0.000 claims description 3
- JRKICGRDRMAZLK-UHFFFAOYSA-N peroxydisulfuric acid Chemical compound OS(=O)(=O)OOS(O)(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-N 0.000 claims description 3
- FHHJDRFHHWUPDG-UHFFFAOYSA-N peroxysulfuric acid Chemical compound OOS(O)(=O)=O FHHJDRFHHWUPDG-UHFFFAOYSA-N 0.000 claims description 3
- 239000012286 potassium permanganate Substances 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- VFWRGKJLLYDFBY-UHFFFAOYSA-N silver;hydrate Chemical compound O.[Ag].[Ag] VFWRGKJLLYDFBY-UHFFFAOYSA-N 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 3
- 229960001922 sodium perborate Drugs 0.000 claims description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 3
- 235000011152 sodium sulphate Nutrition 0.000 claims description 3
- YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 229910021580 Cobalt(II) chloride Inorganic materials 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 4
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims 4
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 claims 4
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 claims 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 claims 2
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 claims 2
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 claims 2
- 229910021529 ammonia Inorganic materials 0.000 claims 2
- 239000001569 carbon dioxide Substances 0.000 claims 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 2
- 229910002091 carbon monoxide Inorganic materials 0.000 claims 2
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Substances O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 claims 2
- CMMUKUYEPRGBFB-UHFFFAOYSA-L dichromic acid Chemical compound O[Cr](=O)(=O)O[Cr](O)(=O)=O CMMUKUYEPRGBFB-UHFFFAOYSA-L 0.000 claims 2
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 claims 2
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 claims 2
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 claims 2
- 229910000027 potassium carbonate Inorganic materials 0.000 claims 2
- 150000003464 sulfur compounds Chemical class 0.000 claims 2
- IWAFIJBVEFQJLS-UHFFFAOYSA-N C1=CC=NC=C1.[Cl+] Chemical compound C1=CC=NC=C1.[Cl+] IWAFIJBVEFQJLS-UHFFFAOYSA-N 0.000 claims 1
- 102000018697 Membrane Proteins Human genes 0.000 claims 1
- 108010052285 Membrane Proteins Proteins 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- -1 airgel Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 53
- 239000000523 sample Substances 0.000 description 12
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 8
- 230000029058 respiratory gaseous exchange Effects 0.000 description 8
- 238000010926 purge Methods 0.000 description 7
- 230000000241 respiratory effect Effects 0.000 description 7
- 239000003570 air Substances 0.000 description 5
- 238000011088 calibration curve Methods 0.000 description 5
- 230000002685 pulmonary effect Effects 0.000 description 5
- 239000007789 gas Substances 0.000 description 4
- 238000010561 standard procedure Methods 0.000 description 4
- 238000011109 contamination Methods 0.000 description 3
- 238000007405 data analysis Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 210000000115 thoracic cavity Anatomy 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 229940124446 critical care medicine Drugs 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 241000700198 Cavia Species 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 229920000557 Nafion® Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical class ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012956 testing procedure Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Pulmonology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Physiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261707070P | 2012-09-28 | 2012-09-28 | |
| US61/707,070 | 2012-09-28 | ||
| PCT/US2013/062151 WO2014052741A1 (fr) | 2012-09-28 | 2013-09-27 | Pièce buccale pour la détection précise du no exhalé |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015115962A RU2015115962A (ru) | 2016-11-20 |
| RU2666590C2 true RU2666590C2 (ru) | 2018-09-11 |
Family
ID=50388991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015115962A RU2666590C2 (ru) | 2012-09-28 | 2013-09-27 | Мундштук для точного обнаружения выдыхаемого no |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9931055B2 (fr) |
| EP (1) | EP2900132A4 (fr) |
| JP (1) | JP6396908B2 (fr) |
| KR (1) | KR20150063458A (fr) |
| CN (1) | CN104883971B (fr) |
| BR (1) | BR112015007029A2 (fr) |
| CA (1) | CA2885389A1 (fr) |
| RU (1) | RU2666590C2 (fr) |
| WO (1) | WO2014052741A1 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9420971B2 (en) | 2009-10-24 | 2016-08-23 | Carrot Sense, Inc. | Extracorporeal devices and methods for facilitating cessation of undesired behaviors |
| US11175268B2 (en) | 2014-06-09 | 2021-11-16 | Biometry Inc. | Mini point of care gas chromatographic test strip and method to measure analytes |
| AU2015274801B2 (en) | 2014-06-09 | 2020-10-15 | Biometry Inc. | Low cost test strip and method to measure analyte |
| US10206572B1 (en) | 2017-10-10 | 2019-02-19 | Carrot, Inc. | Systems and methods for quantification of, and prediction of smoking behavior |
| WO2016164484A1 (fr) * | 2015-04-07 | 2016-10-13 | Carrot Sense, Inc. | Systèmes et procédés de quantification et de prédiction d'un comportement tabagique |
| EP3442414A4 (fr) * | 2016-04-12 | 2019-11-06 | ENDO Medical, Inc | Dispositif d'analyse de la respiration |
| CN114859028A (zh) | 2016-07-19 | 2022-08-05 | 生物统计股份有限公司 | 使用批量可校准测试条测量分析物的方法和系统 |
| CN107247085B (zh) * | 2016-08-30 | 2019-08-20 | 无锡市尚沃医疗电子股份有限公司 | 一种同时测定口与鼻呼出气分子的方法与装置 |
| CN106370832B (zh) * | 2016-11-09 | 2024-02-27 | 苏州一呼医疗科技有限公司 | 智能呼气分子诊断系统 |
| US20180174486A1 (en) * | 2016-12-21 | 2018-06-21 | GM Global Technology Operations LLC | Impairment detection device with performance feedback system and method of operating the same |
| JP6558549B2 (ja) | 2017-01-24 | 2019-08-14 | 日本精密測器株式会社 | マウスピースとその製造方法、および呼気検査装置 |
| WO2018170009A1 (fr) | 2017-03-13 | 2018-09-20 | Arizona Board Of Regents On Behalf Of Arizonia State University | Systèmes et procédés de spirométrie à base d'imagerie |
| US11293875B2 (en) | 2017-09-27 | 2022-04-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Method and apparatus for continuous gas monitoring using micro-colorimetric sensing and optical tracking of color spatial distribution |
| US11209417B2 (en) * | 2017-10-12 | 2021-12-28 | Carrot, Inc. | Breath sensor apparatus and methods of use |
| JP7325006B2 (ja) * | 2018-03-30 | 2023-08-14 | パナソニックＩｐマネジメント株式会社 | ガス成分計測装置 |
| JP7189011B2 (ja) * | 2018-12-26 | 2022-12-13 | 日本特殊陶業株式会社 | 呼気ガス検知装置 |
| CN211927449U (zh) * | 2019-06-14 | 2020-11-13 | 切尔卡斯亚有限公司 | 一种水分捕获设备 |
| AU2020338979A1 (en) * | 2019-08-27 | 2022-03-17 | Trudell Medical International Inc. | Smart oscillating positive expiratory pressure device |
| WO2021094986A2 (fr) * | 2019-11-14 | 2021-05-20 | Health Innovision Company Limited | Analyseur de gaz et de substance volatile d'haleine portatif |
| MX2022008186A (es) | 2019-12-30 | 2022-09-23 | Cilag Gmbh Int | Sistemas y metodos para ayudar a individuos en un programa de cambio de comportamiento. |
| CN114901139A (zh) | 2019-12-31 | 2022-08-12 | 麦克内尔股份公司 | 呼吸传感器校准方法和装置 |
| CN117462112A (zh) * | 2023-12-25 | 2024-01-30 | 中科(安徽)智慧健康创新研究院有限公司 | 一种静息代谢率检测设备及检验装置 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020193698A1 (en) * | 2001-05-11 | 2002-12-19 | Eeva Moilanen | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| US20070240987A1 (en) * | 2006-04-14 | 2007-10-18 | Nair Balakrishnan G | Apparatus and Method for Measuring Nitric Oxide in Exhaled Breath |
| US20080107569A1 (en) * | 2006-09-14 | 2008-05-08 | Stefano George B | Detecting nitric oxide |
| WO2009030957A1 (fr) * | 2007-09-07 | 2009-03-12 | Bedfont Scientific Limited | Aappareil et procédé |
| US20100282245A1 (en) * | 2007-01-12 | 2010-11-11 | Alexander Star | Detection of nitric oxide |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI82367C (fi) | 1988-02-11 | 1991-03-11 | Instrumentarium Oy | Till intubationsroer kopplad spirometer och provtagningsfoerbindning i gasanalysator. |
| CA2097363A1 (fr) | 1992-06-03 | 1993-12-04 | Hideo Ueda | Appareil servant a l'examen de l'air expire, et methode d'utilisation clinique |
| ATE191560T1 (de) | 1993-07-06 | 2000-04-15 | Aerocrine Ab | System zur feststellung von no-pegeln in ausgeatmeter luft und diagnostische verfahren für zu abnormalen no-pegeln in beziehung stehenden abweichungen |
| JP3838671B2 (ja) | 1993-10-25 | 2006-10-25 | アークレイ株式会社 | 呼気採取装置 |
| WO1997038307A1 (fr) | 1996-04-09 | 1997-10-16 | Sievers Instruments, Inc. | Procede et dispositif de mesure des composants de l'haleine humaine |
| SE9701150D0 (sv) * | 1997-03-27 | 1997-03-27 | Nitrograf Ab | Anordning för att utvärdera NO-halten i en utandad luftström |
| SE9801532D0 (sv) * | 1998-04-30 | 1998-04-30 | Aerocrine Ab | Device for the collection of exhaled air samples |
| US8360771B2 (en) * | 2006-12-28 | 2013-01-29 | Therametric Technologies, Inc. | Handpiece for detection of dental demineralization |
| US10918308B2 (en) * | 2007-05-18 | 2021-02-16 | Koninklijke Philips N.V. | Respiratory component measurement system including a sensor for detecting orientation or motion |
| US8206311B2 (en) * | 2009-04-01 | 2012-06-26 | Aerocrine Ab | Analyzer for nitric oxide in exhaled breath with multiple-use sensor |
| DE102009016848B4 (de) * | 2009-04-08 | 2011-12-01 | Siemens Aktiengesellschaft | Gas-Analysegerät mit einer Kombination aus Gasentfeuchter und Gaskonverter |
| JP5706893B2 (ja) * | 2009-07-30 | 2015-04-22 | コーニンクレッカ フィリップス エヌ ヴェ | 吐出された一酸化窒素を決定する方法及び装置 |
| JP5763658B2 (ja) * | 2009-11-03 | 2015-08-12 | コーニンクレッカ フィリップス エヌ ヴェ | 呼気中特定ガス濃度の測定装置 |
| CN201870661U (zh) * | 2010-07-26 | 2011-06-22 | 深圳市中核海得威生物科技有限公司 | 一种呼气试验用的气体采样袋 |
| AU2013329171A1 (en) | 2012-10-10 | 2015-04-30 | Arizona Board Of Regents, On Behalf Of Arizona State University | Multifunctional radical quenchers |
-
2013
- 2013-09-27 KR KR1020157010482A patent/KR20150063458A/ko not_active Application Discontinuation
- 2013-09-27 WO PCT/US2013/062151 patent/WO2014052741A1/fr active Application Filing
- 2013-09-27 CN CN201380050749.0A patent/CN104883971B/zh not_active Expired - Fee Related
- 2013-09-27 CA CA2885389A patent/CA2885389A1/fr not_active Abandoned
- 2013-09-27 EP EP13841482.6A patent/EP2900132A4/fr not_active Withdrawn
- 2013-09-27 RU RU2015115962A patent/RU2666590C2/ru not_active IP Right Cessation
- 2013-09-27 JP JP2015534737A patent/JP6396908B2/ja not_active Expired - Fee Related
- 2013-09-27 BR BR112015007029A patent/BR112015007029A2/pt not_active Application Discontinuation
- 2013-09-27 US US14/431,730 patent/US9931055B2/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020193698A1 (en) * | 2001-05-11 | 2002-12-19 | Eeva Moilanen | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| US20070240987A1 (en) * | 2006-04-14 | 2007-10-18 | Nair Balakrishnan G | Apparatus and Method for Measuring Nitric Oxide in Exhaled Breath |
| US20080107569A1 (en) * | 2006-09-14 | 2008-05-08 | Stefano George B | Detecting nitric oxide |
| US20100282245A1 (en) * | 2007-01-12 | 2010-11-11 | Alexander Star | Detection of nitric oxide |
| WO2009030957A1 (fr) * | 2007-09-07 | 2009-03-12 | Bedfont Scientific Limited | Aappareil et procédé |
Non-Patent Citations (1)
| Title |
|---|
| В.Л. ВАКС и др. Применение методов и средств нестационарной спектроскопии субтерагерцовых и терагерцовых диапазонов частот для неинвазивной медицинской диагностики. Оптический журнал, N2, 2012, поступила в редакцию 10.06.2011. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104883971B (zh) | 2018-10-16 |
| BR112015007029A2 (pt) | 2017-07-04 |
| EP2900132A4 (fr) | 2016-07-06 |
| JP6396908B2 (ja) | 2018-09-26 |
| WO2014052741A1 (fr) | 2014-04-03 |
| US9931055B2 (en) | 2018-04-03 |
| CN104883971A (zh) | 2015-09-02 |
| US20150201865A1 (en) | 2015-07-23 |
| JP2016500151A (ja) | 2016-01-07 |
| CA2885389A1 (fr) | 2014-04-03 |
| RU2015115962A (ru) | 2016-11-20 |
| EP2900132A1 (fr) | 2015-08-05 |
| KR20150063458A (ko) | 2015-06-09 |
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