RU2596503C1 - Method of passive immune protection of broiler chickens - Google Patents

Abstract

FIELD: agriculture.

SUBSTANCE: invention relates to agriculture, particularly to poultry farming, and can be used for passive immune protection of broiler chickens. For this purpose an immunostimulating drug prepared from the chickens blood is used, killed at the end of fattening. Allogenic immune serum is used in the form of aerosols for treatment of daily chickens in the same birdhouse at the moment of its filling of daily chickens.

EFFECT: use of the given method enables to perform passive immune protection of livestock in the birdhouse by the set of specific antibodies of an allogenic immune serum, thus providing the principle of non-waste technology.

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Description

The invention relates to poultry, and in particular to methods for increasing the resistance of chickens.

Known methods for the prevention of bird diseases include the method for the prevention of infectious bird laryngotracheitis, RF patent No. 1743608, IPC A61K 39/00, 39/245. The method consists in aerosol administration of a vaccine containing a viral antigen in a culture medium into a poultry organism according to immunization schemes.

The known method allows the successful prevention of ILT and thereby increases the safety of the poultry head, increases the weight gain and egg production of birds.

The disadvantages of this method include the complexity of the manufacture of the vaccine and its high cost

A known method for the prevention of disease of birds (RF patent No. 1671310, A61K 39/00, 37/02). The method consists in using the immunostimulant N-acetylglucosaminyl - (β-1 → 4) N-acetylmuramylolanyl-D-azoglutamine, which is administered intramuscularly at the same time as the vaccine, and then orally in the same dose daily for 3-10 days.

This method allows you to increase immunity and thereby reduce the percentage of death by an average of 2.8 times, and increase the average daily gain by an average of 65.3%.

However, the known method has several disadvantages: intramuscular administration of a vaccine and an immunostimulant causes stress in a bird and requires large labor costs, and also increases the cost of bio-production.

Closest to the proposed is a method of increasing immunity of birds, RF patent 2280982, A61K 67/02. The method consists in using an aqueous suspension of ultradispersed basalt as a stimulant when feeding chickens, feeding chickens and incubating eggs.

Technical challenge

The solution to the technical result is achieved by using prefabricated blood serum of broiler chickens, the so-called allogeneic immune serum - AIS, obtained from the blood collected at the time of slaughter (the principle of waste-free technology) and after its corresponding processing: filtering through Zeitz or Salnikov filters, checking for sterility, harmlessness, toxicity, preserving up to 0.5% phenol concentration, packaging, and use AIS in the form of aerosols for processing day-old chickens at the time of picking the same house, from which horn was sent to slaughter a bird at the end of fattening.

The essence of the protection method is that during the feeding period broiler chickens develop their own antibodies against all biotic environmental factors. The preparation is prepared from the blood of broilers that are killed at the end of feeding, using allogeneic immune serum in the form of aerosols for processing daily chickens in the same house as it is filled with daily chickens.

The daily broiler chickens, at the time of completing the poultry house, are placed in a special chamber 40 × 60 cm in size, in the amount of 80 chickens, and treated with AIS aerosol. AIS aerosol is created at the rate of 1.0 ml / m ³ and is supplied under a pressure of 3.5 atm with an exposure of 10 seconds. Stand 2 minutes and served in the appropriate battery of the house.

The essence of the method is illustrated in tables 1-3.

Example 1

The experiment was taken 1520 day old chickens, which were treated with aerosols AIS. The control was 30,000 chickens not treated with AIS.

Table 1 shows the dynamics of the daily increase in live weight of chickens in the experiment and control.

From table 1 it is seen that when using AIS aerosols, the average live weight of the broiler at the age of 30 days was higher than the control by 34 g.

Example 2

In the first experiment, 1135 day old chickens were taken, which were treated with AIS aerosols. In the control (without treatment) 2137 chickens - analogues were selected. The experience was set in the house number 59.

In the II experiment, 1146 chickens treated with AIS aerosols (experiment) were selected. The control (without AIS processing) was 2128 analog chickens (house No. 66) (Table 2).

From table 2 it can be seen that the chickens treated at the daily age of AIS had a clear advantage over the control counterparts both by the average daily gain in live weight and by the end of feeding, by 180 g. The safety of the chickens both in the experiment and in the control was one level.

Example 3

The experimental group was taken 2612 chickens. Allogeneic immune serum was prepared from the blood of chicken house No. 37, sent for slaughter, and was used on chickens of a new batch during the acquisition of the same house (No. 37).

The control group was represented by chickens-analogues of the experimental group (53790 heads) of the same house, with the only difference being that they were not processed by AIS (Table 3).

From table 3 it is seen that at the end of the feeding, the average slaughter weight of 1 carcass from the experimental group was 133 g higher than in the control, i.e. without AIS processing.

Using AIS, both passive immune protection of the new livestock in a particular house is achieved using a set of antibodies (immunoglobulins produced by an adult livestock during feeding in the same house and transmitted to the new livestock through AIS, as well as saturation of the chickens with all the components necessary for the body that are part of the AIS .

Thus, in a closed cycle of poultry reproduction, the use of a waste-free technology product - the blood of broiler chickens killed at the end of feeding, is extremely effective, environmentally friendly, and can contribute to the production of organic products.

Claims (1)

A method of passive immune protection of broiler chickens, including the use of an immunostimulating drug, characterized in that the preparation is prepared from the blood of broilers that are killed at the end of feeding, using allogeneic immune serum in the form of aerosols for processing daily chickens in the same house at the moment of filling it with daily chickens.