RU2476232C1 - Dr lvkosmodemyanskiy's homeopathic compositions for treating and preventing inflammatory digestive diseases and complications thereof, as well as methods for using them - Google Patents

Abstract

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely agents for treating and preventing inflammatory digestive diseases. A homeopathic composition for treating and preventing inflammatory digestive diseases containing the following ingredients in homoeopathic dilutions: Aconitum napellus, Arnica montana, Belladonna, Bryonia alba, China officinalis, Eupatorium perfoliatum, Ipecacuanha, Mercurius solubilis, Nux vomica, Rhus toxicodendron, Secale cornutum (versions).

EFFECT: homeopathic compositions possess high efficacy in treating and preventing inflammatory digestive diseases.

11 cl, 7 tbl, 8 ex

Description

FIELD OF THE INVENTION

The invention relates to medicine, namely to complex homeopathic compositions (compositions) and methods of their use for the treatment and prevention of acute and chronic inflammatory diseases of the digestive system (digestive system), in particular gastritis, hepatitis, duodenitis, colitis, pancreatitis, cholecystitis, esophagitis, enteritis and others, and their complications.

State of the art

Currently, among the formulations intended for the treatment of acute and chronic inflammatory diseases of the digestive system, a group of homeopathic medicines produced is known:

Richard Bittner AG, Austria - Galstena;

Holding EDAS OJSC (Moscow, Russia) - Gastropan EDAS-954, Gepa EDAS-953, Hepaton EDAS-129, Defekol EDAS-124, Holoeton-EDAS, Kaliris-EDAS;

Doctor N LLC - Aloe-plus (Aloe-plus), Aloe DN (Aloe DN), Berberis-plus (Berberis-plus), Iris-plus (Iris-plus), Kolotsint-plus, Matricaria DN (Matricaria DN) ;

Homeopathic Pharmacy LLC, (Russia, St. Petersburg - Gastrika-GF, Choleit-GF (Choleit-GF);

Biologist Heilmittel Heel GmbH (Biologische Heilmittel Heel GmbH), Germany - Berberis-Homaccord (Berberis-Homaccord®), Gastricumeel (Gastricumeel®), Hepar compositum® (Herar compositum®), Duodenohelpel (Duodenohetel®) , Momordica compositum, Nux vomica-Homaccord (Nux vomica-Homaccord®), Spaskuprel® (Spascupreel®), Helidonium-Homaccord N (Chelidonium-Homaccord N®), Hepel® (Hepeel®);

LLC Talion-A (Russia, Moscow) - Choledius;

Homeopathic Medical and Social Center LLC (Russia, Novosibirsk) - Choledohosan (A.V. Patudin, V.S. Mishchenko, L.I. Ilyenko, L.V. Kosmodemyansky. Homeopathic medicines authorized in the Russian Federation for use in healthcare and veterinary medicine. M., "Sign", 2011, p. 352).

Among the indications for the use of these drugs are mentioned: Gastritis, Gastroduodenitis, Peptic ulcer. Duodenal ulcer, Colitis, Dyspepsia, Constipation, Hepatitis, Hepatosis, Pancreatitis, Cholecystitis, Cholangitis, Dyskinesia of the biliary tract, Gallstone disease, Dyscholia. However, in practice, known agents have a number of significant drawbacks, which limits their use.

In particular, the developers of these drugs did not take into account the typical dynamics of the course and development of acute and chronic inflammatory diseases of the digestive system. Therefore, the compositions proposed by them in their testimonies do not take into account the need for combined and / or sequential use for the prevention and treatment of the most typical and often developing inflammatory diseases of the digestive system. As a rule, the development of acute and chronic inflammatory diseases of the digestive system, in particular: gastritis, cholecystitis, pancreatitis, have a combined course, manifested by typical syndrome complexes:

- pain syndrome;

- spastic syndrome;

- dyspeptic syndrome;

- intoxication syndrome,

which are due to the stage and localization of the developing general and local inflammatory process.

The available formulations do not include all possible combinations of homeopathic preparations necessary for the treatment of gastritis, cholecystitis, colitis, enteritis, constipation, etc., occurring with typical complications. The absence of known complex homeopathic preparations that take into account the possibility of combined use for the prevention and treatment of the most typical forms of developing complications in inflammatory diseases of the digestive system requires the formation of additional formulations for the prevention and treatment of acute and chronic gastritis, cholecystitis, and other inflammatory diseases of the digestive system that occur with most common complications. So, in the existing group of drugs there are no formulations whose indications for use would take into account the prevention and treatment of complications of acute gastritis, colitis, etc., for example, such as esophagitis, enteritis.

Along with this, the known compositions contain similar components and many of them use identical doses of these components. Therefore, well-known drugs are difficult to combine with each other. For example, with the development of such a typical complication of acute and exacerbation of a chronic inflammatory disease of the digestive system, such as gastritis, it is unacceptable to combine the use of Gastropan EDAS-954 with Defecol EDAS-124, since both drugs contain the same components in an identical dose, which can cause overdose. For example, a component such as Bryonia cretica (Bryonia alba) is used in a single dose (C6) in various formulations. The same situation is observed when comparing Gastric GF (Hastrica-GF) with Choleit-GF (Choleit-GF), where, in particular, Lycopodium clavatum is contained in both drugs and also in the same dose (C6), also as well as Taraxacum officinale - C3 in Hepa EDAS-953 and Holeton-EDAS.

A significant disadvantage of the known formulations is the lack of the possibility of not only combined, but also consistent use of these compounds in the considered pathology of the digestive system.

In addition, a significant drawback of many of the known homeopathic medicines that have indications for use: "inflammatory diseases of the digestive system" is the presence in the complex preparations of components not approved for use in the Russian Federation (A.V. Patudin, V.S. Mishchenko , L.I. Ilyenko, L.V. Kosmodemyansky. Homeopathic medicines approved in the Russian Federation for use in healthcare and veterinary medicine. M., “Valang”, 2011, p. 352).

For example, the preparation Momordica compositum (Momordica compositum) of the company “Biologische Heilmittel Heel, GmbH” contains the component Mandragorae radice siccato, and the preparation Hepar compositum® (Hepar compositum®) of the same company includes a number of components that are not approved for use in the Russian Federation: Hepar suis, Duodenum suis and others

The above disadvantages of the known formulations necessitate the creation of homeopathic compositions, including a group of one-component homeopathic preparations, with the compositions proposed below that overcome these disadvantages and are highly effective in the treatment and prevention of inflammatory diseases of the digestive system and their complications.

Disclosure of invention

Thus, the technical result of the invention is to increase the effectiveness of the treatment and prevention of acute and chronic inflammatory diseases of the digestive system (digestive system) and their complications.

In addition, the technical result of the invention is the rapid achievement of a positive therapeutic effect in inflammatory diseases of the digestive system and their complications, in particular, the rapid reduction of typical complaints (pain, nausea, vomiting, increased temperature reaction, etc.).

The next technical result, which is achieved by the created invention, is to reduce the duration of the course of inflammatory diseases of the digestive system and their complications.

In addition, the technical result of the invention is the compatibility of homeopathic compositions used for the treatment and prevention of inflammatory diseases of the digestive system, in particular acute and chronic gastritis and their complications (in particular, gastric ulcer, reflux esophagitis, etc.).

Further, the technical result achieved using the complex homeopathic compositions according to this invention is to increase the adaptive reactions of the body, which reduces the incidence of inflammatory diseases of the digestive system and the development of typical complications.

The next technical result achieved by the invention is to reduce the incidence of severe forms of complications requiring the use of antibacterial, anti-inflammatory drugs, analgesics and other types of conventional therapy, which has a high incidence of side effects and has a number of contraindications.

An additional advantage of the created compositions is the presence on the territory of the Russian Federation of pharmacies with a production homeopathic department, which have all their components authorized for use on the territory of the Russian Federation and, therefore, the possibility of their manufacture.

The above technical results are achieved by creating and using complex homeopathic compositions that have the following compositions (each of the compositions below may contain at least one homeopathically acceptable target supplement, in particular a solvent or carrier):

- homeopathic composition No. 1 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions:

Aconitum napellus, Arnica montana, Belladonna, Bryonia alba, China officinalis, Eupatorium perfoliatum, Ipecacuanha, Mercurius solubilis, Nux vomica, Rhus toxicodendron, Secale cornutum;

- homeopathic composition No. 2 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Arsenicum album, Elaterium, Carbo vegetabilis, Cuprum metallicum, Lachesis mutus, Podophyllum peltatum, Veratrum album;

- homeopathic composition No. 3 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Anacardium orientale, Antimonium crudum, Argenutm nitricum, Cocculus indicus, Kalium carbonicum, Pulsatilla;

- homeopathic composition No. 4 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Ammonium muriaticum, Causticum, Manganum aceticum, Robinia, Sulfuricum acidum;

- homeopathic composition No. 5 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Aloe socotrina, Alumina, Calcarea carbonica, Copaiva officinalis, Graphites, Opium, Platinum metallicum;

- homeopathic composition No. 6 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Carduus marianus, Chamomilla recutita, Chelidonium majus, Dioscorea villosa, Leptandra virginica, Lycopodium clavatum, Magnesia muriatica, Myrica triceraerife, Myrica tricella Taraxacum officinales;

- homeopathic composition No. 7 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Conium maculatum, Iodium, Iris versicolor, Momordica balsamina, Phosphorus, Spongia tosta;

- homeopathic composition No. 8 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Agaricus muscarius, Caulophyllum thalictroides, Colocynthis, Geisemium sempervirens, Magnesium phosphoricum, Passiflora incarnata;

- homeopathic composition No. 9 for the treatment and prevention of inflammatory diseases of the digestive system / containing the following ingredients in homeopathic dilutions: Aesculus hippocastanum, Calcarea fluorica, Collinsonia canadensis, Hamamelis virginica, Nitricum acidum, Paeonia officinalis, Vipera berus;

- homeopathic composition No. 10 for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Cascarilla, Zingiber officinale, Quassia amara, Kreosotum, Natrium carbonicum, Niccolum metallicum.

Homeopathically acceptable target additives for use in the compositions according to this invention can be selected from a wide range of excipients known to a person skilled in the art, in particular purified water, ethyl alcohol of various concentrations, glycerin, milk sugar, vegetable oils, petrolatum, lanolin, cocoa butter and etc.

The present invention also relates to a method for treating inflammatory diseases of the digestive system, comprising administering to the patient at least one of the above homeopathic compositions,

The developed formulations are made and applied according to the rules of homeopathy.

The implementation of the invention

The authors of the present invention for the first time proposed a single concept for the formation of a group of one-component homeopathic preparations, from which the compositions of the invention were compiled with indications for use for the prevention and treatment of inflammatory diseases of the digestive system, in particular acute and chronic gastritis, which allowed more effective treatment of these diseases and prevent the development severe forms of complications.

The following is a complete list of one-component homeopathic medicines included in the developed composition.

1. Aconitum napellus,

2. Aesculus hippocastanum,

3. Aqaricus muscarius,

4. Aloe socotrina,

5. Alumina,

6. Ammonium muriaticum,

7. Anacardium orientate,

8. Antimonium crudum,

9. Argenutm nitricum,

10. Arnica montana,

11. Arsenicum album,

12. Belladonna,

13. Bryonia alba,

14. Calcarea carbonica,

15. Calcarea fluorica,

16. Carbo vegetabilis,

17. Carduus marianus,

18. Cascarilla,

19. Caulophyllum thalictroides,

20. Causticum,

21. Chamomilla recutita,

22. Chelidonium majus,

23. China officinalis,

24. Cocculus indicus,

25. Collinsonia canadensis,

26. Colocynthis,

27. Conium maculatum,

28. Copaiva officinalis,

29. Cuprum metallicum,

30. Dioscorea villosa,

31. Elaterium,

32. Eupatorium perfoliatum,

33. Gelsemium sempervirens,

34. Graphites,

35. Hamamelis virginica,

36. Iodium,

37. Ipecacuanha,

38. Iris versicolor,

39. Kalium carbonicum,

40. Kreosotum,

41. Lachesis mutus,

42. Leptandra virginica,

43. Lycopodium clavatum,

44. Magnesia muriatica,

45. Magnesium Phosphoricum,

46. Manganum aceticum,

47. Mercurius solubilis,

48. Momordica balsamina,

49. Myrica cerifera,

50. Natrium carbonicum,

51. Natrium sulfuricum,

52. Niccolum metallicum,

53. Nitricum acidum,

54. Nux vomica,

55. Opium,

56. Paeonia officinalis,

57. Passiflora incarnata,

58. Phosphorus,

59. Platinum metallicum,

60. Podophyllum peltatum,

61. Ptelea trifolita,

62. Pulsatilla,

63. Quassia amara,

64. Rhus toxicodendron,

65. Robinia,

66. Secale cornutum,

67. Spongia tosta,

68. Sulfuricum acidum,

69. Taraxacum officinales,

70. Veratrum album,

71. Vipera berus,

72. Zingiber officinale.

For the formation of this group and subgroups of drugs, an analysis of the database was initially used, which includes more than 3,500 items of homeopathic monotherapy and more than 100,000 rubrics of symptoms and syndrome complexes using modern computer programs on homeopathy (Homeopathic DAR software, RADAR, EH, CARA Professional, etc. .). For example, based on only one symptom of the course of gastritis - heartburn, an analysis was carried out between 202 single-component homeopathic remedies for 49 symptoms that accompany and manifest during gastritis in various stages, with subsequent clinical studies confirming the effectiveness of the developed compositions.

In homeopathic compositions according to the invention, the following dosages (dilutions) of the components can be used:

preparation on a decimal scale of dilution (1:10), is indicated in the description text - D,

preparation on a hundredth dilution scale (1: 100), indicated in the text of the description - C,

cooking according to the method of S. N. Korsakov, is indicated in the description text - K,

preparation according to the Hahnemann method ("Organ of the medical art", 6th edition, paragraph 270), is indicated in the text of the description - LM;

non-dynamized dosage forms can also be used, indicated in the description text - Q.

All these methods are known to a person skilled in the art, and a specific sequence of actions and techniques is disclosed in published sources, referenced below in the present description.

The dilution technique, as well as the dilution degree for the compositions of the present invention, can be selected by a doctor using a homeopathic method of treatment, and depends on the condition of the patient, the dynamics of his symptoms, reaction to the treatment, etc.

A method of manufacturing compositions according to the invention

First, homeopathic matrix tinctures of each individual component are made.

Matrix homeopathic tincture is prepared from trituration in the case of insoluble feedstocks and from a liquid form using soluble feedstocks. Trituration or tincture is prepared by potentiating (dynamizing) a phased dilution of the starting material with a neutral solvent (water, alcohol, milk sugar, etc.) using mechanical grinding or shaking.

In the case of the manufacture of a homeopathic tincture from an insoluble feedstock, trituration is first made by potentiation to the degree of dynamization that is capable of dissolving in alcohol or in water without residue. Preferably, a 3C or 6D degree of dynamization (potentiation) is used for this purpose.

Further, matrix homeopathic tinctures of one-component drugs are potentiated to form the main dynamization scale used in the manufacture of complex preparations, so that their degree of potentiation is one step lower than in the prescription. It is necessary to take into account the degree of toxicity of the initial medicinal raw material.

For example, homeopathic remedies such as: Lachesis mutus, Mercurius solubilis, Hahnemanni, Arsenicum album should preferably not be used below average homeopathic dilutions, therefore matrix homeopathic tinctures should preferably not be used below 5C or 11D dilutions, and matrix tinctures of homeopathic preparations such as Arnica montana Chamomilla recutita, Eupatorium perfoliatum, can be used directly in tincture and in low D or C dilutions.

For the manufacture of a homeopathic mixture, matrix tinctures of one-component preparations in the potencies indicated in the recipe are used, which are taken in equal proportions and mixed in a solvent of the specified volume or applied to an inert carrier (for example, sugar grains).

As indicated above and confirmed by the illustrative example given for the manufacture of the claimed compositions, the simplicity of their manufacture also relates to an additional advantage of these compositions. The compositions according to the invention can be manufactured by any pharmacy having a production homeopathic department, since only registered single-component homeopathic medicines are used in the manufacture, and the manufacturing procedure complies with the generally accepted regulations for the manufacture of complex homeopathic preparations of intra-pharmacy production. The manufacture of compositions according to the invention is regulated by applicable law and regulatory documentation (“Collection of Pharmacopoeial Articles on Homeopathy” under the scientific editorial member of the Academy of Medical Sciences, Prof. R.U. Khabriev, Scientific Center for Expertise of Medical Applications. Federal Service for Supervision in the field of healthcare and social development. Moscow, 2005, p.3-41).

It should also be noted that the manufacturing technology of homeopathic compositions according to this invention depends on the starting material (starting active substances) and target additives, which can be purified water, ethyl alcohol of various concentrations, glycerin, milk sugar, vegetable oils, petrolatum, lanolin, oil cocoa etc. (I.I. Krasnyuk, G.V. Mikhailova. Pharmaceutical homeopathy. Edited by N.A. Zamarenov, M., Academy, 2005).

In homeopathic compositions according to the invention, the following dosages (dilutions) of the components can be used:

Composition No. 1:

Aconitum napellus 2D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Arnica montana Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Belladonna 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Bryonia alba 1D-30D, 3C-30C, 50K-1000K, 1LM-30LM; China officinalis Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Eupatorium perfoliatum Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Ipecacuanha 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Mercurius solubilis 8D-30D, 4C-30C, 50K-1000K, 1LM-30LM; Nux vomica 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Rhus toxicodendron 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Secale cornutum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition No. 2:

Arsenicum album 12D-30D, 6C-30C, 50K-1000K, 1LM-30LM; Elaterium Q, 2D-30D, 2C-30C, 50K-1000K, 1LM-30LM; Carbo vegetabilis 10D-30D, 10C-30C, 50K-1000K, 1LM-30LM; Cuprum metallicum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Lachesis mutus 12D-30D, 6C-30C, 50K-1000K, 1LM-30LM; Podophyllum peltatum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Veratrum album 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition No. 3:

Anacardium orientale 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Antimonium crudum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Argenutm nitricum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Cocculus indicus 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Kalium carbonicum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Pulsatilla Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition No. 4:

Ammonium muriaticum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Causticum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Manganum aceticum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Robinia 4D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Sulfuricum acidum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition No. 5:

Aloe socotrina Q, 1D-30D, 1C-30C, 50K-1000K, 1LM-30LM; Alumina 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Calcarea carbonica 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Copaiva officinalis 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Graphites 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Opium 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Platinum metallicum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition number 6:

Carduus marianus Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Chamomilla recutita Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Chelidonium majus Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Dioscorea villosa 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Leptandra virginica 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Lycopodium clavatum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM, 8C; Magnesia muriatica 3D-30D, 2C-30C, 50K-1000K, 1LM-30LM; Myrica cerifera 3D-30D, 2C-30C, 50K-1000K, 1LM-30LM; Natrium sulfuricum 3D-30D, 2C-30C, 50K-1000K, 1LM-30LM; Ptelea trifolita 3D-30D, 2C-30C, 50K-1000K, 1LM-30LM; Taraxacum officinales Q, 3D-30D, 2C-30C, 50K-1000K, 1LM-30LM.

Composition No. 7:

Conium maculatum 10D-30D, 5C-30C, 50K-1000K, 1LM-30LM; Iodium 8D-30D, 4C-30C, 50K-1000K, 1LM-30LM; Iris versicolor 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Momordica balsamina 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Phosphorus 8D-30D, 4C-30C, 50K-1000K, 1LM-30LM; Spongia tosta 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition number 8:

Caulophyllum thalictroides 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Colocynthis 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Gelsemium sempervirens 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Magnesium phosphoricum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Passiflora incarnata 3D-30D, 4C-30C, 50K-1000K, 1LM-30LM.

Composition No. 9:

Aesculus hippocastanum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Calcarea fluorica 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Collinsonia canadensis 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Hamamelis virginica 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Nitricum acidum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Paeonia officinalis 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Vipera berus 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

Composition No. 10:

Cascarilla 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Zingiber officinale 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Quassia amara 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Kreosotum Q, 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Natrium carbonicum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM; Niccolum metallicum 3D-30D, 3C-30C, 50K-1000K, 1LM-30LM.

In the above embodiments of the compositions of the present invention, all homeopathic dilutions (dosages) are given as an alternative. So, for example, in composition No. 1 Aconitum napellus can be prepared on a decimal dilution scale (1:10), while dilutions are indicated as 2D-30D. If the same component is prepared on a hundredth dilution scale (1: 100), then dilutions are indicated as 3C-30C. In the case of preparation according to the method of S. N. Korsakov, dilutions are designated as 50K-1000K, and in the case of preparation according to the Hahnemann method (Organ of Medical Art, 6th edition, paragraph 270) - 1LM-30LM. However, in one composition, it is not intended to use dilutions prepared in accordance with different methods.

As noted above, the components of the composition of the present invention can be used in conventional homeopathic dilutions and should not be limited to specifying specific dosages, as they are selected by a specialist depending on the severity of certain symptoms, age, dynamics of the patient's condition, concomitant diseases and several other factors .

However, in a preferred embodiment, the components of the compositions of the invention are contained in the following dosages.

Composition No. 1:

Aconitum napellus 5C, 7C; Arnica montana 3C; Belladonna 5C, 7C; Bryonia alba 5C, 7C; China officinalis 3C; Eupatorium perfoliatum 3D; Ipecacuanha 5C; Mercurius solubilis 6C; Nux vomica 5C, 7C, 9C; Rhus toxicodendron 4C; Secale cornutum 3C.

Composition No. 2:

Arsenicum album 8C, Elaterium 3C, Carbo vegetabilis 10D, Cuprum metallicum 6C, Lachesis mutus 7C, Podophyllum peltatum 4C, Veratrum album 5C.

Composition No. 3:

Anacardium orientale 4C, 10C; Antimonium crudum 6C, 9C; Argenutm nitricum 5C, 12C; Cocculus indicus 3C; Kalium carbonicum 7C; Pulsatilla 8C.

Composition No. 4:

Ammonium muriaticum 8C; Causticum 6C, 9C; Manganum aceticum 4C; Robinia 3C; Sulfuricum acidum 5C, 7C, 10C.

Composition No. 5:

Aloe socotrina 2C, 6C; Alumina 5C; Calcarea carbonica 4, 10C, 15C; Copaiva officinalis 3C; Graphites 9C; Opium 7C; Platinum metallicum 8C, 11C.

Composition number 6:

Carduus marianus 2D, Chamomilla recutita 7C, 9C; Chelidonium majus 6D; Dioscorea villosa 3D; Leptandra virginica 4D; Lycopodium clavatum 3C, 8C, 12C; Magnesia muriatica 6C; Myrica cerifera 2C; Natrium sulfuricum 5C; Ptelea trifolita 5D; Taraxacum officinales 8D, 10C.

Composition No. 7:

Conium maculatum 7C; Iodium 6C; Iris versicolor 3C; Momordica balsamina 2C; Phosphorus 5C; Spongia tosta 4C, 8C.

Composition number 8:

Agaricus muscarius 6C; Caulophyllum thalictroides 3C; Colocynthis 4C, 8C; Gelsemium sempervirens 7C; Magnesium phosphoricum 5C; Passiflora incarnata 2C.

Composition No. 9:

Aesculus hippocastanum 3D; Calcarea fluorica 5C; Collinsonia canadensis 3C; Hamamelis virginica 4C; Nitricum acidum 6C; Paeonia officinalis 2C, Vipera berus 7C.

Composition No. 10:

Cascarilla 2C; Zingiber officinale 3C; Quassia amara 3D; Kreosotum 4C; Natrium carbonicum 6C; Niccolum metallicum 5C.

These compositions can be assigned separately and / or mixed immediately prior to administration, taking into account the main indications both during self-treatment and in complex combination treatment.

The compositions of the invention can be presented, including in the following dosage forms:

alcohol drops - are recommended for longer storage and for patients suffering from diabetes;

water drops - have the shortest shelf life and are recommended for washing the mucous membranes of the eyes, nose and for infants;

grinding (opodeldok) - it is recommended for local application with the integrity of the skin to enhance the effect by increasing local blood supply;

granules - are recommended as the most convenient form of use, but are contraindicated in patients with diabetes;

ointment / gel / oil - recommended for a longer method of local exposure and for the formation of a protective film on the surface of the skin or mucous membranes;

suppositories - recommended in cases of difficult sublingual intake of the indicated composition (for example, infants or elderly patients).

The following table No. 1 contains recommendations for determining the minimum single age-related dose of the compositions of the invention.

Table number 1 Minimum single age dose Age Minimum single age dose From 0 months to 2 years 1 drop (granule) is dissolved in 1 tsp. (5 ml) drinking water 2 years to 7 years old and elderly 2 drops (granules) to dissolve in 1 tsp. (5 ml) drinking water From 7 years old to 14 years old and older dissolve up to 3 drops (granules) in 1 dl. (10 ml) drinking water From 14 years to 21 years dissolve up to 4 drops (granules) in 1 tbsp. (15 ml) drinking water For adults at the rate of 1 cap. (1 gran.) Per 10 kg of body weight dissolved in 1 tbsp. (15 ml) drinking water

An individual single dose is determined by the individual reactivity of the body, the stage of the pathological process and the general condition of the patient and corresponds to the number of granules, drops, which causes a positive response of the body to the accepted composition. In most cases, the individual dose of the composition taken corresponds to the minimum age dose. In practice, the individual single dose is preferably determined by taking the minimum age-related single dose (see Table No. 1) with an interval of 15 minutes before the onset of a positive therapeutic effect, after which the total number of granules or drops is added up. Subsequent medications, during the occurrence or amplification of complaints corresponding to the indications of a homeopathic composition, may begin with an individual single dose. An individual single dose can also be selected taking into account the absence of the desired therapeutic effect from taking the minimum dose by gradually increasing the amount of composition to be taken until the desired therapeutic effect is achieved from its single dose. In case of strengthening the protective reaction of the body (homeopathic exacerbation) or the appearance of other complaints (development of the pathogenesis of the components), it is necessary to take a break in taking medications and, with subsequent appointments, reduce the amount of the composition taken.

The following regimens for administering the compositions of the invention are recommended.

In preferred embodiments, for the prevention of acute inflammatory diseases of the digestive system (acute condition) and typical complications, a single age-related dose is prescribed once a week for a month, with a repeat of no more than once every 2-3 months.

For the treatment of subacute inflammatory diseases of the digestive system (subacute condition) or chronic disease (chronic condition) in the acute stage, a single age-related dose is prescribed with a frequency of 2-4 times a day until improvement with a subsequent decrease in the frequency of administration.

For the treatment of acute inflammatory diseases of the digestive system (acute condition), the following mode of administration of the compositions according to this invention is preferably used. Dissolve a single age-related dose in 250 ml of drinking water and take 1 teaspoon or tablespoon (depending on age) with a gradual increase in the interval by 15-30 minutes to improve well-being, after which the intake interval is extended to 1-4 hours. The frequency of administration on the first day is no more than 5-8 times, and on the second day - no more than 4-5 times.

The invention is illustrated by the following examples of its practical use, showing the effectiveness of the developed homeopathic compositions for the treatment and prevention of inflammatory diseases of the digestive system and their complications.

Example 1

Patient S., age 29 years, height 175 cm, weight 72.5 kg.

Diagnosis: Rotovirus infection (A.08.0).

Complaints: pain in the stomach, aggravated by palpation, nausea, vomiting, loose stools, temperature - 38 ° C. Was examined by a therapist at home. The prescribed treatment was carried out: rehydron, motilium sublingually. The temperature returned to normal, but there was a sharp weakness, periodically loose stools, and did not adhere to dietary recommendations. Negatively refers to tablet dosage forms, in connection with which he applied for homeopathic treatment. The homeopathic composition No. 1 was prescribed in alternation with the homeopathic composition No. 2 (the dosage form is alcohol drops) according to the treatment regimen for the subacute condition with an additional intake at the time of increasing complaints according to the treatment regimen for the acute condition, while the well-being improved, the frequency of administration decreased.

When re-examined after a week, the patient noted an improvement in well-being on the 2nd day of taking the prescribed homeopathic compositions. On the 4th day of taking homeopathic compositions, the complaints went completely and the patient stopped the prescribed treatment.

Example 2

Patient R., age 39 years, height 175 cm, weight 77 kg.

Diagnosis: Chronic cholecystitis (K 81.1) Hypomotor biliary dyskinesia (according to ultrasound).

Complaints: bitterness in the mouth, heaviness in the right hypochondrium, periodically “nausea”. Associates aggravation with an error in the diet (fat soup, "seeds"). He independently took no-shpa, allochol irregularly.

Objectively: phrenicus symptom (+), gall bladder point (+), Ortner symptom (+). The liver is palpated at the edge of the costal arch, the edge is smooth, painless. Palpated spasmodic sigmoid colon. Signs of flatulence are noted.

The physician at the place of residence recommended choleretic antispasmodics: duspatalin, no-spa, diet No. 5. The patient noted some improvement, but after three days of treatment an allergic reaction appeared in the form of urticaria throughout the body, accompanied by itching, the condition was stopped by cetrin and a hypoallergenic diet. Due to intolerance to antispasmodics, the patient is recommended homeopathic therapy (HT) for a course of 3 months (see Table No. 2), with exacerbation of complaints, additionally take homeopathic compositions: No. 1, No. 6, No. 8, mixing together in 1-2 tbsp. tablespoons of drinking water, and take in a single dose 3 times a day until improved, then reduce the frequency of administration. Upon repeated admission after 3 months, the patient noted a steady improvement in well-being and a decrease in the frequency of exacerbation of existing complaints from the gallbladder.

To consolidate the achieved results, recommendations were given: repeat the course over the next 3 months. After the course, a control ultrasound of the liver and gall bladder was performed. With repeated administration after a repeated course, according to the ultrasound data, expressed pathological changes were not determined. There were no complaints from the patient. On examination, pathological signs were not detected.

Table number 2 Day of the week and time of reception / Number of the composition Monday Tuesday Wednesday Thursday Friday Saturday Resurrection No. 1 Morning Morning Number 8 Day Day Number 6 Evening Evening

Take for 2 weeks, then one week break.

Repeat course for 3 months.

Example 3

Patient S., age 49 years, height 190, weight 96 kg.

Diagnosis: Gastroesophageal reflux with esophagitis (K21.0).

Complaints of constant heartburn, belching of air, pain after eating behind the sternum.

Anamnesis: on FGS GER with the phenomena of esophagitis. For a long time he took antacids, proton pump inhibitors (omez, soars). The effect is incomplete and unstable. On the ECG, there were no signs of coronary insufficiency.

Given the chronic nature of the disease and the lack of a full clinical effect of the therapy, surgical treatment was proposed, which the patient refused and sought homeopathic therapy.

Homeopathic compositions No. 1, No. 3, No. 4 were prescribed according to the scheme (see Table No. 3), additionally taking medications during the period of increasing complaints according to the acute and subacute dosage regimen (see rules of use).

Upon repeated admission after 6 months, the patient noted persistent positive dynamics: the severity of complaints decreased, the frequency of exacerbation attacks decreased, which quickly stopped with the recommended GT.

Table number 3 Day of the week and time of admission / Monday Tuesday Wednesday Thursday Friday Saturday Resurrection Composition number No. 1 Morning Morning Number 3 Day Day Number 4 Evening Evening

Take for 2 weeks, then one week break. Repeat course for 6 months.

Example 4

Patient B., age 44 years. Height is 160 cm. Weight is 57 kg.

Diagnosis: Chronic pancreatitis (K 86.1) incomplete remission.

At the beginning of the year, after an error in the diet (salads with mayonnaise, oily fish, cakes), nausea, vomiting appeared, and therefore outpatient treatment was prescribed - diet No. 5P and rehydron. The treatment did not improve. After 3 days, she was sent to the surgical department for inpatient treatment, where after 5 days of infusion therapy the patient was discharged with a diagnosis of Chronic pancreatitis. Remission.

Over the next three months, the condition remained unstable, with errors in the diet, pain attacks resumed, weight loss was 4.5 kg. Given the lack of therapeutic effect of the ongoing standard drug therapy of chronic pancreatitis, I addressed the possibility of GT.

He was prescribed: a course of treatment for 2 months (see Table No. 4) and homeopathic compositions No. 1, No. 7, No. 6, No. 8 alternately with an interval of 10-40 minutes according to the acute and subacute regimen with the resumption of pain.

Table number 4 Day of the week and time of reception / Number of the composition Monday Tuesday Wednesday Thursday Friday Saturday Resurrection No. 1 Morning Morning Morning Number 7 Morning Morning Morning Number 6 Evening Evening Evening Number 8 Evening Evening Evening

Take for 2 weeks, then one week break. Repeat course for 2 months.

With repeated use after 2 months, the patient noted persistent remission. Recommendations are given for further treatment and taking GT for 6 months.

Example 5

Patient V., age 41 years, height 170 cm, weight 75 kg.

Diagnosis: gastric ulcer and 12-p. intestines (K 26.0). Chronic gastroduodenitis (K29.9).

Complaints: periodically occurring late and aching pains in the epigastrium, calming down after eating and antacid drugs.

Anamnesis: Suffers from YABZH and 12-p. Gut for the last 10 years, the cause of exacerbation - stress in the family - experiences associated with the death of a close relative; anxiety and anxiety about the future of children, irregular nutrition. On FGS antral gastritis, deformation 12-p. intestines, bulbitis. HP +. During eradication therapy, a complication of pseudomembranous colitis occurred. He is afraid to take drugs, uses only antacids urgently. For the above reason, on the advice of friends, expressed a desire to try an "alternative treatment method" in connection with which I decided to turn to GT. Assigned homeopathic compositions: No. 1, No. 2, No. 8 mixing in 1-2 tablespoons of drinking water, according to the acute scheme. Additionally, a 6-month course has been drawn up, including the intake of homeopathic compositions: No. 1A, No. 2, No. 8, see Table No. 5.

Table number 5 Day of the week and time of reception / Number of the composition Monday Tuesday Wednesday Thursday Friday Saturday Resurrection No. 1 Morning Morning Number 2 Morning Morning Number 8 Evening Evening

Take for one week, then one week break. Repeat course for 6 months.

Upon repeated admission after 6 months, the patient noted persistent remission. Recommendations are given for further treatment and administration of GT for 12 months.

Example 6

Patient K., Age 36 years, height 180 cm, weight 88 kg.

Diagnosis: Hypomotor intestinal dyskinesia (K 58.9). Constipation (K 59.0).

Suffers from constipation for five years. Abuses laxatives (regulax, senade, paraffin oil). Over the past 6 months, flatulence has intensified. I applied for homeopathic therapy in connection with a decrease in the desired effect of taking laxatives and increased flatulence.

Homeopathic therapy was prescribed: No. 5 - in the morning, No. 6 - in the evening - once a day, a single dose - 9 drops per 1 tbsp. drinking water for 2 weeks, then every other day for a month, followed by monitoring of well-being. After 1.5 months, he noted a steady improvement - the chair became regular, flatulence passed.

The examples of successful treatment of patients of different ages suffering from acute, subacute and chronic inflammatory diseases of varying severity of the digestive system are part of an extensive clinical experience with the use of homeopathic compositions according to the following claims.

Example 7

Patient D., age 32 years, height 168, weight 75 kg.

Diagnosis: Chronic atrophic gastritis (K 29.4). Constipation (K 59.0). Hemorrhoids (184). Chronic anal fissure (K 60.1).

I applied for a GT for a chronic anal fissure that occurred 6 months after the birth (29 years) against the background of developing atrophic gastritis, accompanied by constipation and hemorrhoids. Over the past 2 years, standardized treatment has been carried out, prescribed by a gastroenterologist and proctologist, but the desired positive result was not achieved.

The compositions were assigned: No. 1, No. 3, No. 5, No. 9 - according to the scheme (Table No. 6).

Table number 6 Day of the week and time of reception / Number of the composition Monday Tuesday Wednesday Thursday Friday Saturday Resurrection No. 1 Morning Morning Morning Number 3 Morning Morning Morning Number 5 Evening Evening Evening Number 9 Evening Evening Evening

Course - 2 weeks admission, 1 week break for 3 months.

Additionally, composition No. 5 in dosage form — rectal suppositories, in front of the stool, composition No. 9 in the form of an ointment locally in the area of the anal fissure after stool.

With repeated admission, the patient noted persistent improvement. Appetite improved, stool returned to normal, hemorrhoids stopped aggravating, and an anal fissure passed.

Example 8

Patient N., age 26 years, height 175, weight 69 kg.

Diagnosis: Esophagitis with gastroesophageal reflux (K 21.0).

He complained of belching with air and eaten food that develops after eating, chest pain, heartburn, a feeling of bitterness in the mouth.

The ball was prescribed GT: composition No. 10 before eating, composition No. 1 after eating, taking 3-4 times a day - the minimum single dose.

Health monitoring was carried out after 2 weeks. The patient noted a slight improvement: heartburn and bitterness in the mouth decreased.

The patient was adjusted to an individual dose of medication and was recommended to take 9-12 drops of the drug, dissolving in a small amount of drinking water. When improving, reduce the frequency of admission.

With subsequent monitoring of well-being after 3 weeks, the patient noted a normalization of well-being and a decrease in the frequency of taking medications up to 1-2 times a day. The patient was given recommendations for the further course of treatment (Table No. 7).

Table number 7 Day of the week and time of reception / Number of the composition Monday Tuesday Wednesday Thursday Friday Saturday Resurrection No. 1 Morning Morning Morning Number 10 Morning Morning Morning One week break

Take the prescribed composition for 6 months. With increasing complaints, take medication according to an acute-subacute regimen (see Table No. 1).

With the subsequent monitoring of the patient’s well-being, persistent remission was noted over the past 3 months, in connection with which the medication was discontinued.

Claims (10)

1. Homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Aconitum napellus, Arnica montana, Belladonna, Bryonia alba, China officinalis, Eupatorium perfoliatum, Ipecacuanha, Mercurius solubilis, Nux vomndum, Seculus, toxic . 2. Homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Arsenicum album, Elaterium, Carbo vegetabilis, Cuprum metallicum, Lachesis mutus, Podophyllum peltatum, Veratmm album. 3. Homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Anacardium orientale, Antimonium crudum, Argenutm nitricum, Cocculus indicus, Kalium carbonicum, Pulsatilla. 4. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Ammonium muriaticum, Causticum, Manganum aceticum, Robinia, Sulfuricum acidum. 5. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Aloe socotrina, Alumina, Calcarea carbonica, Copaiva officinalis, Graphites, Opium, Platinum metallicum. 6. A homeopathic composition for the treatment and prophylaxis of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Carduus marianus, Chamomilla recutita, Chelidonium majus, Dioscorea villosa, Leptandra virginica, Lycopodium clavatum, Magnesia muriatica, Myrica cerifera, Myrica cerifera, Myrica cerifera, Merrica tricidae Taraxacum officinales. 7. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Conium maculatum, lodium, Iris versicolor, Momordica balsamina, Phosphorus, Spongia tosta. 8. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Agaricus muscarius, Caulophyllum thalictroides, Colocynthis, Gelsemium sempervirens, Magnesium phosphoricum, Passiflora incarnate. 9. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Aesculus hippocastanum, Calcarea fluorica, Collinsonia canadensis, Hamamelis virginica, Nitricum acidum, Paeonia officinalis, Vipera berus. 10. A homeopathic composition for the treatment and prevention of inflammatory diseases of the digestive system, containing the following ingredients in homeopathic dilutions: Cascarilla, Zingiber officinale, Quassia amara, Kreosotum, Natrium carbonicum, Niccolum metallicum.