RU2470670C1 - Medical plaster-type fixer - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to medicine, more specifically to chemical-pharmaceutical industries and medical equipment. What is described is a fixer representing an adhesive tape consisting of paper base 45-55 g/m and a pressure sensitive adhesive coating one of the base sides. The adhesive layer is protected by siliconised paper.

EFFECT: agent provides higher adhesive properties, better vapour permeability, does not irritate skin, possess higher viability.

5 cl, 2 tbl

Description

The invention relates to chemical and pharmaceutical industries and medical equipment and can be used in the manufacture of multifunctional biologically active structures, for fixing dressings and objects.

Known adhesive tape used as a protective coating for the skin (and.with. No. 460873, IPC A61L 15/06, 1971). The adhesive contains a copolymer of methacrylic acid and butyl acrylate or butyl methacrylate. Various drugs can be introduced into it.

The disadvantage of this adhesive tape is that its adhesive ability is manifested in an environment with a pH of 3.5-5.5, but with increased acidity, skin irritation is possible up to damage to the epidermis.

The closest analogue of the invention is a medical adhesive tape consisting of a base and adhesive applied to one side of it (RU No. 2173176, IPC A61L 15/58, published on 09/10/2001). The composition of the adhesive includes acrylic emulsions made from a copolymer of butyl acrylate and acrylic acid, or butyl acrylate and acrylic and methacrylic acid, or esters of acrylic acid containing carboxyl groups, as well as an aqueous solution of ammonia of 25% concentration in an amount of 1.5-5% . adhesive pH 6-8.5, viscosity 10-30 thousand mPa · s. The amount of adhesive based on 20-80 g / m ² . As a basis, elastic films with a mass of 15-90 g / m ² , or non-woven materials with a mass of 30-60 g / m ² or woven materials with a mass of 70-120 g / m ² are taken.

The disadvantages of this adhesive tape are the high consumption of adhesive to achieve the necessary adhesive characteristics, due to the large mass of the coating, low vapor permeability, insufficient environmental friendliness of the products due to the use of polymeric materials in them.

New technical results from the use of the present invention are to reduce the consumption of adhesive while maintaining the necessary adhesive characteristics, increase the vapor permeability of the adhesive layer due to a decrease in its weight, increase the environmental friendliness of products due to the use of cellulose paper as the basis.

These results are achieved by the fact that in a medical fixing agent of a plaster type, consisting of a base and a pressure sensitive adhesive deposited on one side thereof, consisting of an acrylic emulsion prepared from a copolymer of acrylic acid and a substance from a series including butyl acrylate, as well as an ammonia solution, taken in an amount providing an adhesive pH of 6.8-7.5, according to the invention, a number of substances additionally include vinyl monomers, while the acrylic emulsion is prepared from a mixture of copoly emulsions Erov acrylic acid and butyl acrylate and acrylic acid and vinyl monomers at a ratio in the adhesive, in parts by weight, 50-95: 5-50. As a base, wood pulp paper with a mass of 45-55 g / m ^{2 is used} , the adhesive contains a thickener, which is used as a composition of "Collacral VAL" in an amount that provides adhesive viscosity in the range of 10-30 thousand MPa · s, and the mass adhesive base is 20-25 g / m ² .

The medical fixing means of the plaster type are made as follows. From the prepared emulsions of copolymers of acrylic acid and butyl acrylate and acrylic acid and vinyl monomers, mixtures with a given polymer content are prepared, with stirring at a speed of the mixer blades 60-80 rpm, 25% aqueous ammonia solution is added until a pH of 6.8- 7.5 and, if necessary, a thickener in the amount necessary to achieve a viscosity of 10-30 thousand MPa · s. The obtained adhesives are applied using a doctor blade method on a siliconized surface of a protective layer of paper weighing 65 g / m ² . Then the protective paper is duplicated with the base paper.

Using the same technology, samples are prepared according to examples. The characteristics of the samples are measured by known methods. As emulsions, the compositions Ruzin 21A1 and AK-256A are used.

Table 1 shows the adhesive composition of the examples, pH and viscosity. Using each of the compositions according to examples 1-6 prepare samples of fixing means with a mass of adhesive coating of 20, 25 and 30 g / m ² .

Table 1 Examples The composition of the adhesive composition, parts by weight Ruzin 21A1 (TU 2241-013-578 45504-2005) AK-256A (TU 2241-013-55373366-2008) Water ammonia 25% concentration (GOST 24147-80) Thickener "Collacral VAL" company "BASF" parts by weight Viscosity thousand MPa · s parts by weight pH one fifty fifty 1,54 7.0 0.8 twenty 2 35 65 1.87 7.0 0.5 21 3 25 75 1.89 7.1 0.3 twenty four twenty 80 1.93 6.9 0.2 19 5 5 95 2.08 7.2 - 19 6 (prototype) - one hundred 2,35 7.1 - 19

The data on the results of testing the adhesive properties and vapor permeability of all the materials obtained are given in table 2.

An analysis of the results shows that the fixing means according to the proposed technical solution have higher adhesive characteristics with a lower adhesive coating mass, increased vapor permeability, and due to the use of cellulose paper as a base, a significantly higher biodegradation rate in natural conditions, i.e., higher environmental friendliness.

table 2 Physico-mechanical properties of the obtained material Quality indicators of the material obtained By examples one 2 3 four 5 6 (prototype) 1. The mass of the adhesive layer with an area of 1 m ² , g twenty 25 thirty twenty 25 thirty twenty 25 thirty twenty 25 thirty twenty 25 thirty twenty 25 thirty 2. The peeling resistance of the adhesive layer of the material from the metal, N / m (according to 4.5 TU 9393-196-00281022-2011) 197 230 280 213 240 294 226 256 295 265 310 362 150 175 230 120 148 195 3. The vapor permeability, g / m ² for 24 hours (according to GOST 21472-81) 745 631 430 752 650 435 755 683 440 778 690 445 803 695 448 - 698 450

Claims (5)

1. A patch-type medical fixative, consisting of a base and an adhesive applied to one side of it, consisting of an acrylic emulsion made from a copolymer of acrylic acid and a substance from a series including butyl acrylate, as well as an ammonia solution taken in an amount that ensures the pH of the adhesive on the level of 6.8-7.5, characterized in that a number of substances includes vinyl monomers, while the acrylic emulsion is prepared from a mixture of emulsions of copolymers of acrylic acid and butyl acrylate, acrylic acid and vinyl monomers when their ratio in adhesive, parts by weight, 50-95: 5-50, respectively. 2. The tool according to claim 1, characterized in that the basis of the use of paper from wood pulp with a mass of 45-55 g / m ² . 3. The tool according to claim 1, characterized in that the adhesive contains a thickener. 4. The tool according to claim 3, characterized in that the composition "Collacral VAL" is used as a thickener in an amount that provides an adhesive viscosity of 10-30 thousand mPa · s. 5. The tool according to claim 1, characterized in that the mass of adhesive based on is equal to 20-25 g / m ² .