RU2336892C2 - Method of obtaining of extract for maintenance of organism vital activity - Google Patents

Abstract

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention concerns medicine area. Perform digestion on birch buds alcohol in several stages. At the first stage presoak 100 g of birch buds with the maintenance of essential oils of 5-8% in a tightly closed glass container in 300 ml of alcohol-rectificate of 95-96.2% strength and condition for 14-16 hours. At the second stage in the obtained solution at the first stage add as the catalyst potable water in amount of 300-306 ml at temperature of 45°C and condition within 2.5-4 hours up to obtaining of white cream colour by the solution and depression of alcohol strength to 45%. At the third stage add 0.5 litres of alcohol of 95-96.2% strength in a solution, condition the solution in a dark place at temperature of 24-26°C within two weeks in a hermetically sealed container up to obtaining of brownish-green colour. At the fourth stage add 180-200 ml of potable water with temperature 36°C and 180-200 ml of alcohol of 95-96.2% strength before depression of alcohol strength to 62.5% and digest within two weeks up to obtaining of dark brown colour.

EFFECT: decrease of toxicity of the product.

2 cl, 3 tbl, 3 ex

Description

The invention relates to medicine, namely to methods for the production of medicines based on plant materials.

A known method of preparing an extract of birch buds infused on the basis of 90% alcohol (1: 5) in relation to the raw material to the extractor. Used for lotions for purulent wounds, mastitis, furunculosis, etc. [one].

The main disadvantage of the known method (1: 5) in relation to the raw material to the extractor when using 90% alcohol is the viscosity (stickiness) of the resulting product, which for external use in our case as an antispasmodic for all organs and systems of the body is not suitable. Insoluble substances found in birch buds can cause a feeling of not only an unpleasant sensation, irritation, but also poisoning. Saponins located in birch buds have this effect [1; 2].

Also known tincture based on birch buds and alcohol with a strength of 70% (1: 5) for a similar purpose [3].

The main significant disadvantage of this method is also the viscosity, the supersaturation of the solution with substances located in birch buds, i.e. incomplete dissolution and neutralization of toxic substances.

The claimed invention eliminates the above disadvantages, and the extract obtained by this method when used increases the therapeutic effect.

The problem set by the inventor is solved in the invention due to the fact that the infusion of birch buds is carried out using rectified alcohol with a strength of 95-96.2% in four stages, where in the first stage, 100 g of birch soaked in a hermetically sealed glass container in 300 ml of rectified alcohol kidneys with an essential oil content of 5-8% and can withstand 14-16 hours. At the second stage, drinking water in the amount of 300-306 ml at a temperature of 45 ° C is added to the resulting solution at the first stage to better dissolve the substances found in birch buds. In the third stage, add 0.5 l of alcohol with a strength of 95-96.2%, keep the solution in a dark place for better dissolution of the substances and the sedimentation rate and precipitation of the remaining undissolved substances, and in the fourth final stage, the remaining 180-200 ml are added to the solution water with a temperature of 36 ° C and 180-200 ml of alcohol with a strength of 95-96.2% until the alcohol strength is reduced to 62.5%, and insist for two weeks to obtain from light brown to brown or dark brown, which depends on the percentage of birch buds u irnogo oil, a colorant, the degree of dissolution, which in turn depends on the strength of the alcohol and the degree of purification. As a result, we have the complete dissolution (melting) of substances found in birch buds under the influence of alcohol with a strength of 95-96.2% and water (in the second stage at a temperature of 45 ° C, in the fourth at a temperature of 36 ° C). In total, the ratio of raw materials to the extractor and the percentage of water was (1: 10: 5). In this form, the solution does not contain toxic substances, which means that it can be rubbed in any quantity, while such substances as ascorbic acid, vitamin P groups, provitamin A and glucose, the main energy-generating substrate, which is free in lymph, blood, cerebrospinal fluid, brain tissue, cardiac and skeletal muscles, is instantly absorbed through the pores of the skin when used and has both a pronounced antispasmodic analgesic effect and a stimulating effect, normalizes to oxygen metabolism at the cellular level.

Thus, the proposed extract in its practical use (rubbing) increases the tone of the body’s vital activity, does not cause side effects, as the test results showed, which confirms the applicant’s thesis about the nontoxicity of the extract. In addition, the task is solved in the invention due to the fact that the preparation of the extract is carried out at a room temperature of 24-26 ° C and kept in a dark meta, for better dissolution of substances in solution.

The above set of essential features is not known both from healthcare practice, and from patent-technical and specialized literature. So, this set of essential features is new and forms significant differences. The whole set of new, essential features is connected by a causal relationship, which is solved by the invention.

Given these theses, it is legitimate to conclude that the proposed solutions meet the criteria: "novelty" inventive step. The claimed solution, set forth by a set of essential features, when implemented, provides a solution to the problem, and more than once. Based on this, it is legitimate to conclude that the proposed solution meets the criterion of "industrial applicability".

The inventive essence of the proposed solution is tested in a laboratory. The results of this testing are given below.

Example 1: Birch buds with an essential oil content of 5 to 6%.

They took 100 g of birch buds with the content of essential oils from 5 to 6%. They were poured into a reaction glass vessel with a hermetically sealed stopper and added 300 ml of rectified alcohol to it and kept for 16 hours in a warm place. Then, drinking water with a temperature of 45 ° C was added to the solution as a catalyst to better dissolve the substances in birch buds. The mixture takes the form of milk, and the percentage of alcohol by strength was 45%. Dissolution time 2.5 hours.

At the next stage, alcohol in the amount of 0.5 liters and a strength of 95% was added to the solution and left it for 2 weeks in a dark place. The solution acquired a greenish-brown color, with a small amount of substances precipitated. At the next stage, drinking water was added in a thin stream at a temperature of 36 ° С and alcohol until its strength reached 62.5%. In this case, the initial product was completely dissolved, and the infusion acquired a milky-white color. The solution was kept for two weeks. At the final stage, the percentage of alcohol strength should be 62.5% in it.

Example 2: Birch buds with an essential oil content of 6-7%.

100 g of birch buds with an essential oil content of 6-7% were taken, they were poured into a reaction glass vessel with a hermetically sealed stopper and 300 ml of rectified alcohol 96.2% were added to it, kept for 14 hours in a warm place, then into the solution in As a catalyst, 306 ml of drinking water with a temperature of 45 ° C was added to better dissolve the substances in them. The mixture took the form of milk, and the percentage of alcohol by strength was 45%. At the same time, the substances contained in the birch buds began to dissolve. Dissolution time 3 hours.

At the next stage, alcohol in an amount of 500 ml and a strength of 96.2% was added to the solution and left it for two weeks in a dark place. The solution turned greenish brown, with a small amount of undissolved substance precipitating. At the next stage, 180-200 ml of drinking water at a temperature of 45 ° С and alcohol in an amount of 180-200 ml with a strength of 96.2% were added in a thin stream until the alcohol strength in solution of 62.5% was reached. In this case, complete dissolution of the starting product occurred. The solution was kept for two weeks. The extract is ready for use, while its color will be brown.

Example 3: Birch buds with an essential oil content of 7-8%.

100 g of birch buds with an essential oil content of 7-8% were taken, they were poured into a reaction glass vessel with a hermetically sealed stopper and 300 ml of rectified alcohol with a strength of 95% were added to it, kept for 15 hours in a dark place. Then, drinking water with a temperature of 45 ° C was added to the solution as a catalyst to better dissolve the substances in solution. The mixture takes the form of milk, and the percentage of alcohol by strength is 45%. In this case, most of the substances found in birch buds are dissolved. Dissolution time 4 hours.

At the next stage, rectified alcohol with a strength of 95% in the amount of 500 ml was added to the solution and left for two weeks in a dark place. The solution turned greenish brown. However, a small amount of substances precipitated. At the next stage, 180-200 g of drinking water was added in a thin stream at a temperature of 36 ° C and the same amount of alcohol with a strength of 95% until its strength reached 62.5%. In this case, the substances contained in the birch buds are completely dissolved, after the solution is kept for two weeks. In this case, its color will become brown. The extract is ready to use.

According to hygienic requirements for the quality of drinking water, it should be safe from an epidemic point of view, harmless in chemical composition, including radioactive substances.

The summary data of Table 1-3 is presented below:

Table 1 Example Rectified alcohol 95% ml Water Exposure time, h Alcohol strength,% ml t Stage 1 300 - - 16 95 2 stage - 300 45 2,5 45 3 stage 500 - - 336 62.5 4th stage 180-200 180-200 36 336 62.5

Table 2. Example Rectified alcohol 96.2%, ml Water Exposure time, h Alcohol strength,% ml t Stage 1 300 - - fourteen 96.2 2 stage - 306 45 3 45 3 stage 500 - - 336 62.5 4th stage 180-200 180-200 36 336 62.5 Table 3. Example Distilled alcohol 95%, ml Water Exposure time, h Alcohol strength,% ml t Stage 1 300 - - fifteen 95 2 stage - 300 45 four 45 3 stage 500 - - 336 62.5 4th stage 180-200 180-200 36 336 62.5

These examples indicate that the use of birch buds and other components to obtain the extract is possible strictly within certain limits.

A small percentage of substances precipitated is allowed.

The therapeutic effect of using an extract obtained by one of the above methods is similar.

The extract is completely non-toxic and has a pleasant herbal odor. Used to rub into a sore spot. It does not have side effects. Indicated for use for external rubbing in children, adults, the elderly.

Information sources

1. L. Ya. Sklyarevsky, I. A. Gubanov “Medicinal plants in everyday life” M .: Rosselkhozizdat, 1986, p. 45.

2. NP Maksyutina “Herbal Medicines” Kiev: Health Publishing House, 1985, p.69-84.

3. V. Anipko “Treatment of influenza and catarrhal diseases using traditional medicine” St. Petersburg: DIAMOND SMIO PRESS, 1997, p.24-25.

Claims (2)

1. The method of obtaining the extract to maintain the vital functions of the body, which consists in infusion of alcohol from birch buds, characterized in that the infusion of birch buds is obtained in several stages, where at the first stage in a hermetically sealed glass container soaked in 300 ml of rectified alcohol with a strength of 95-96 , 2% 100 g of birch buds with an essential oil content of 5-8% and incubated for 14-16 hours, at the second stage, in the first solution, drinking water in the amount of 300-306 ml is added to the resulting solution at a temperature of 45 ° C and maintained in t 2.5-4 hours before giving the solution a white, milky color and lowering the alcohol strength to 45%, at the third stage, add 0.5 l of alcohol to the solution with a strength of 95-96.2%, keep the solution in a dark place at a temperature of 24- 26 ° C for two weeks in a hermetically sealed container until brownish-green in color, and in the fourth stage add 180-200 ml of drinking water with a temperature of 36 ° C and 180-200 ml of alcohol with a strength of 95-96.2% to reduce the strength alcohol up to 62.5% and insist for two weeks until a dark brown color is obtained. 2. The method according to claim 1, characterized in that the preparation of the extract is carried out at a room temperature of 24-26 ° C and kept in a dark place at a temperature of 24-26 ° C.