RU2333007C3 - POLYPEPTIDE VACCINES FOR BROAD PROTECTION AGAINST A SERIES OF GENERATIONS OF MENINGOCOCCIS WITH INCREASED VIRULENCE - Google Patents

POLYPEPTIDE VACCINES FOR BROAD PROTECTION AGAINST A SERIES OF GENERATIONS OF MENINGOCOCCIS WITH INCREASED VIRULENCE

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Publication number
RU2333007C3
RU2333007C3 RU2005114366A RU2005114366A RU2333007C3 RU 2333007 C3 RU2333007 C3 RU 2333007C3 RU 2005114366 A RU2005114366 A RU 2005114366A RU 2005114366 A RU2005114366 A RU 2005114366A RU 2333007 C3 RU2333007 C3 RU 2333007C3
Authority
RU
Russia
Prior art keywords
protein
meningococcis
generations
series
protection against
Prior art date
Application number
RU2005114366A
Other languages
Russian (ru)
Other versions
RU2333007C2 (en
RU2005114366A (en
Original Assignee
Глаксосмитклайн Байолоджикалс Са
Filing date
Publication date
Priority claimed from GB0223741A external-priority patent/GB0223741D0/en
Priority claimed from GB0305831A external-priority patent/GB0305831D0/en
Application filed by Глаксосмитклайн Байолоджикалс Са filed Critical Глаксосмитклайн Байолоджикалс Са
Publication of RU2005114366A publication Critical patent/RU2005114366A/en
Application granted granted Critical
Publication of RU2333007C2 publication Critical patent/RU2333007C2/en
Publication of RU2333007C3 publication Critical patent/RU2333007C3/en

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Claims (7)

1. Композиция для индуцирования гуморального иммунного ответа у млекопитающего, содержащая пять менингококковых антигенов: (1) белок «NadA»; (2) белок «741»; (3) белок «936»; (4) белок «953» и (5) белок «287»,1. Composition for inducing a humoral immune response in a mammal, containing five meningococcal antigens: (1) protein "NadA"; (2) protein "741"; (3) protein "936"; (4) "953" protein and (5) "287" protein, в которой белок NadA включает SEQ ID NO: 2,wherein the NadA protein comprises SEQ ID NO: 2, белок «741» и белок «936» экспрессированы в виде одной полипептидной цепи, включающей SEQ ID NO: 8,protein "741" and protein "936" are expressed as one polypeptide chain, including SEQ ID NO: 8, белок «953» и белок «287» экспрессированы в виде одной полипептидной цепи, включающей SEQ ID NO: 7.the "953" protein and the "287" protein are expressed as a single polypeptide chain comprising SEQ ID NO: 7. 2. Композиция по п.1 для использования в качестве лекарственного средства.2. Composition according to claim 1 for use as a medicine. 3. Применение композиции по любому из предыдущих пунктов в производстве лекарственного средства для предотвращения и/или лечения заболевания, вызванного Neisseria.3. The use of a composition according to any of the preceding claims in the manufacture of a medicament for the prevention and/or treatment of a disease caused by Neisseria. 4. Полипептид для индуцирования гуморального иммунного ответа у млекопитающего, имеющий аминокислотную последовательность, выбранную из группы, состоящей из SEQ ID NO: 2, 7 и 8.4. A polypeptide for inducing a humoral immune response in a mammal, having an amino acid sequence selected from the group consisting of SEQ ID NOs: 2, 7 and 8.
RU2005114366A 2003-10-02 POLYPEPTIDE VACCINES FOR BROAD PROTECTION AGAINST A SERIES OF GENERATIONS OF MENINGOCOCCIS WITH INCREASED VIRULENCE RU2333007C3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0223741A GB0223741D0 (en) 2002-10-11 2002-10-11 Composition with five meningococcal antigens
GB0223741.0 2002-10-11
GB0305831.0 2003-03-13
GB0305831A GB0305831D0 (en) 2003-03-13 2003-03-13 Broad protection meningococcal vaccines
GB0309115.4 2003-04-22

Publications (3)

Publication Number Publication Date
RU2005114366A RU2005114366A (en) 2006-02-10
RU2333007C2 RU2333007C2 (en) 2008-09-10
RU2333007C3 true RU2333007C3 (en) 2023-08-14

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