RU2207865C1 - Method of treatment of iodine-deficient states - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: invention proposes method for treatment of patients with iodine-deficient states by oral intake of mineral water "Ustkachkinskaya 1/99" with the total mineralization 8.2-8.6 g/dm³, 2 times per a day in the dose 10 ml/kg/day, every day, for 21-22 days. EFFECT: improved treatment method, expanded assortment of agents of indicated designation. 3 ex

Description

 The invention relates to medicine, namely to balneology and physiotherapy.

 Iodine is an element necessary for the normal growth and development of a person. The most common manifestation of iodine deficiency is goiter. Endemic and other diseases caused by iodine deficiency represent an important medical and social problem. The existence of goiter endemic in the Urals, associated with iodine deficiency, has been known since the 30s. At present, the prevalence of goiter has increased significantly, especially among children and adolescents, which according to different authors is from 8 to 50% of the total population. The following factors contribute to this: inadequate iodine prophylaxis, increased radiation background, the appearance of new strumogens (thiacinates, heavy metal salts, trace elements deficiency). As a result of the cessation of preventive measures in recent years, there is a clear tendency to increase iodine deficiency. Not only the child’s brain suffers from this, but also his hearing, visual memory and speech. Iodine deficiency can affect the functioning of vital organs and lead to a delay in the physical development and growth of the child.

 For the treatment and prevention of iodine deficiency conditions, various methods are used: seafood, iodized salt, bread, and the use of medications ("Iodine deficiency conditions in children." Lecture 1. Scientific Center for the Health of Children and Adolescents of the Russian Academy of Medical Sciences. Moscow, 1998).

 Disadvantages: lack of effectiveness, the presence of contraindications, such as allergic reactions.

 The invention is aimed at solving problems: increasing the efficiency of the method, expanding the means for the treatment of iodine deficiency conditions.

These tasks are achieved by ingesting Ustkachkinskaya 1/99 mineral water with a total mineralization of 8.2-8.6 g / m ³ at a dose of 10 ml / kg / day, taking it 2 times a day 30 minutes before meals daily in within 21-22 days.

Ustkachkinskaya water of the well 1/99, depth 47.0 m with a total salinity of 8.2-8.6 g / dm ³ refers to the average saline sulphate-chloride calcium-sodium water (Cl 57-60, SO ₄ 38-43, Na 65 -72, Ca 21-22 mg / equiv%). In terms of mineralization and the ratio of the main macrocomponents, it is close to the Ergeninsky type (GOST 13273-88, group XVII).

 Mineral water wells 1/99 is recommended for drinking treatment at the resort; industrial bottling of this water as a canteen is also possible.

 This sulfate-chloride calcium-sodium mineral water is indicated for drinking treatment of diseases of the digestive system; endocrine system diseases, nutritional disorders and metabolic disorders.

 For the treatment of iodine deficiency conditions, Ustkachkinskaya 1/99 mineral water has not been previously used.

The method is as follows. The patient is recommended to take Ustkachkinskaya 1/99 mineral water with a total mineralization of 8.2-8.6 g / dm ³ 2 times a day 30 minutes before meals at a dose of 10 ml / kg / day daily for 21-22 days.

Specific performance examples
Example 1
Child J., 7 years old. Since birth, lives in the village of Ust-Kach-II of operative childbirth, birth weight 2.900. He was breast-fed for up to 8 months. Suffers from frequent respiratory diseases (4-5 times a year). Observed by a neurologist about mental retardation.

 The examination was conducted: a general blood test, a general urine test - without pathology, a urine test for ioduria from 11/24/01 - 8.5 μg / dl.

 On palpation of the thyroid gland, its increase was determined to 0-1 tbsp.

 In the conditions of the children's factory "Spark", the Ustkachkinskaya 1/99 was treated with drinking mineral water at a dose of 10 ml / kg of weight per day 2 times a day 30 minutes before meals, course 22 days.

 On the 7th day of treatment, the iodine content in the urine increased to 20.7 μg / dl (N 10-30 μg / dl), the indicator remained normal until the end of the course, and 6 days after the end of treatment, the ioduria level was 16.6 μg / dl .

Example 2
Child Z., 6 years old. Visits the children's factory "Spark" from 3 years of age.

 From the anamnesis: a child from a pathologically progressing pregnancy, I premature birth. Born with a mass of 1.800. From birth on artificial feeding. Observed by a neurologist about cerebral palsy, spastic tetraparesis. Colds are sick 3-4 times a year.

 The examination was conducted: a general blood test, a general urine test - without pathology, the iodine content in the urine - 6.8 μg / dl.

 Palpation of the thyroid gland revealed its increase to I-II art.

 The child received treatment with Ustkachkinskaya 1/99 drinking mineral water at a dose of 10 ml / kg of weight per day 2 times a day 30 minutes before meals, course 22 days.

 On the 7th day of treatment, the iodine content in the urine reached normal values (12.3 μg / dl).

Example 3
Child P., 5 years old. Visits the children's factory "Spark" resort of Ust-Kachka.

 From the anamnesis: a child from a III abnormal pregnancy, I urgent delivery. Born with a mass of 3.250. Breastfeeding up to 12 months. Observed by an allergist about allergic bronchitis.

 Examination was performed: a general blood test - eosinophilia (9%), a general urinalysis - without pathology. The iodine content in the urine is 16.9 mcg / dl. The thyroid gland during palpation is not enlarged.

 The Ustkachkinskaya 1/99 was treated with drinking mineral water at a dose of 10 ml / kg of weight per day 2 times a day 30 minutes before meals, course 21 days.

 On the 7th day of treatment, the urinary iodine content was 16.9 μg / dl, on the 14th day of treatment the iodine level remained the same (16.9 μg / dl), and on the 21st day of treatment it increased to 23.7 μg / dl.

 The positive effect of using the proposed method is as follows: the absence of contraindications; allergy prevention. Along with the treatment of iodine-deficient conditions, the treatment of concomitant diseases occurs: pathologies of the gastrointestinal tract, metabolic disorders and eating disorders.

Claims (1)

A method of treating iodine deficiency conditions by ingesting iodine in the composition of products and medicines, characterized in that the mineral water "Ustkachkinskaya 1/99" with a total salinity of 8.2-8.6 g / dm ³ is used as a source of iodine, taking it 2 times per day at a dose of 10 ml / kg / day, daily for 21-22 days.