RU2107504C1 - Method for recovering lipids from medicinal muds - Google Patents

Abstract

FIELD: balneology; chemical industry. SUBSTANCE: as-mined muds is subjected to extraction with organic solvent, followed by thickening extract. EFFECT: shorter process duration; increased yield of final product. 1 tbl

Description

 The invention relates to the pharmaceutical industry, namely to the preparation of biologically active substances from pelloid raw materials used for balneological treatment.

 Known methods for producing lipids from therapeutic mud by extraction of dry mud with oil / 1 /, alcohol / 3 /, a mixture of polar and non-polar solvents / 2, 4 /.

 Closest to the proposed is a method of producing lipids from therapeutic mud, which consists in drying the mud in air to a moisture content of 12%, soaking it with 95% ethanol at PH 9.0 and extraction with ethanol or a mixture of ethanol with a non-polar solvent in a ratio of 5: 1 / 5 / (prototype).

A disadvantage of the known methods is the high duration and complexity of the process:
- drying the dirt in air leads to the oxidation of the lipids contained in it, resulting in a decrease in the yield of the target product;
- grinding and granulation of air-dried mud requires significant energy and material costs and the use of special equipment: mills, granulators.

 These shortcomings lead to a decrease in the yield of the target product and a high duration of the process.

 The aim of the invention is to reduce the duration of the process, increasing the yield of the target product used for the preparation of medicines and perfumes and cosmetics / 7 - 9 /.

 This goal is achieved by eliminating the stage of drying the mud from the process.

 Example. 2.0 kg of native mud with a moisture content of 45-50% is extracted with an organic solvent and concentrated by one of the methods described in the prototype / 5 /, and the target product is standardized by a known method / 6 /.

 The table shows the data on determining the yield of the target product depending on the duration of extraction with ethanol according to the method described in the prototype (method A) and according to the proposed method (method B - as an example).

 As can be seen from the table, the proposed method can significantly increase the yield of the target product (by 65%) and significantly reduce the duration of the process (2 to 3 times).

 The method makes it possible to increase the amount of a drug manufactured from the target product from 1.5 kg (according to the method described in the prototype) to 2.5 kg with a carotenoid content of at least 1.2 mg.

Literature:
1. Copyright certificate 1172559 USSR, 1983.

 2. Copyright certificate 825080, USSR, 1981.

 3. Proceedings of the Omsk Medical Institute. Omsk, 1961, N34, p. 135 - 139.

 4. Copyright certificate 404479, USSR, 1974.

 5. RU, patent, 2043100, cl. A 61 K 37/22, 1992.

 6. Temporary pharmacopoeial article 42-2915-92.

 7. Pekhov A. V. et al. Use of extracts of spicy plants in the production of canned food. Canning and vegetable drying industry. 1969, N 7, p. 12 - 15.

8. Meerov Ya.S. et al. Use of CO ₂ -extracts in cosmetics, M., TsNIITZI pishcheprom, 1971, 23 pp.

 9. Temporary pharmacopoeial articles 42-2915-92, 42-2916-92, 42-2917-92.

Claims (1)

 A method of producing lipids from therapeutic mud, including extraction with an organic solvent and thickening of the extract, characterized in that the native mud is directly subjected to extraction.

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