RU2020113341A3 - - Google Patents
Download PDFInfo
- Publication number
- RU2020113341A3 RU2020113341A3 RU2020113341A RU2020113341A RU2020113341A3 RU 2020113341 A3 RU2020113341 A3 RU 2020113341A3 RU 2020113341 A RU2020113341 A RU 2020113341A RU 2020113341 A RU2020113341 A RU 2020113341A RU 2020113341 A3 RU2020113341 A3 RU 2020113341A3
- Authority
- RU
- Russia
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
USPCT/US2017/051553 | 2017-09-14 | ||
PCT/US2017/051553 WO2018053123A1 (en) | 2016-09-14 | 2017-09-14 | Method and compositions for treating viral infection |
US201862698365P | 2018-07-16 | 2018-07-16 | |
US62/698,365 | 2018-07-16 | ||
PCT/US2018/042226 WO2019055119A1 (en) | 2017-09-14 | 2018-07-16 | Method and composition for treating viral infection |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2020113341A RU2020113341A (en) | 2021-10-15 |
RU2020113341A3 true RU2020113341A3 (en) | 2021-10-15 |
Family
ID=65723839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2020113341A RU2020113341A (en) | 2017-09-14 | 2018-07-16 | METHOD AND COMPOSITION FOR VIRAL INFECTION TREATMENT |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP3681508A4 (en) |
JP (3) | JP6820450B2 (en) |
KR (2) | KR20210107904A (en) |
AU (2) | AU2018334386B2 (en) |
CA (1) | CA3075729A1 (en) |
IL (2) | IL285232B (en) |
MX (1) | MX2020002883A (en) |
RU (1) | RU2020113341A (en) |
WO (1) | WO2019055119A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112689510B (en) * | 2020-03-31 | 2022-02-01 | 菲尼克斯生物技术公司 | Methods and compositions for treating coronavirus infection |
US11806359B2 (en) | 2020-03-31 | 2023-11-07 | Phoenix Biotechnology, Inc. | Method and compositions for treating Coronavirus infection |
KR102464428B1 (en) * | 2020-03-31 | 2022-11-04 | 피닉스 바이오테크놀러지 인코포레이티드. | Methods and compositions for treatment of coronavirus infection |
EP4009981B1 (en) | 2020-03-31 | 2023-08-16 | Phoenix Biotechnology, Inc. | Method and compositions for treating coronavirus infection |
FR3109297A1 (en) * | 2020-04-19 | 2021-10-22 | Ephyla | "New non-protein furin inhibitor" |
WO2022094816A1 (en) * | 2020-11-04 | 2022-05-12 | Janssen Pharmaceuticals, Inc. | Solid formulation |
US20230310612A1 (en) * | 2022-04-01 | 2023-10-05 | Alexia Reif | Anti-viral composition and method for preparing the same |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1299100C (en) | 1986-05-13 | 1992-04-21 | Huseyin Ziya Ozel | Extracts of nerium species, methods of preparation and use therefor |
US5236132A (en) | 1992-01-03 | 1993-08-17 | Vortec, Inc. | Gradient-force comminuter/dehydrator apparatus and method |
US5598979A (en) | 1995-04-20 | 1997-02-04 | Vortec, Inc. | Closed loop gradient force comminuting and dehydrating system |
CA2191923C (en) | 1996-12-03 | 2000-10-24 | Ji-Won Yoon | Portulaca oleracea and tumor cell growth |
ATE522220T1 (en) | 1998-05-19 | 2011-09-15 | Res Dev Foundation | TRITERPONE COMPOSITIONS AND METHODS OF USE THEREOF |
AU6056999A (en) | 1998-09-24 | 2000-04-10 | Ozelle Pharmaceuticals, Inc. | Extract of nerium species, pharmaceutical composition thereof and methods for preparation thereof |
US6517015B2 (en) | 2000-03-21 | 2003-02-11 | Frank F. Rowley, Jr. | Two-stage comminuting and dehydrating system and method |
US6569842B2 (en) | 2000-08-18 | 2003-05-27 | Board Of Trustees Of The University Of Illinois, The | Method of preparing and use of prodrugs of betulinic acid derivatives |
US9931316B2 (en) * | 2004-01-06 | 2018-04-03 | Paul Edward Stamets | Antiviral activity from medicinal mushrooms and their active constituents |
US6715705B2 (en) | 2001-03-16 | 2004-04-06 | Frank F. Rowley, Jr. | Two-stage comminuting and dehydrating system and method |
ATE295087T1 (en) | 2001-04-09 | 2005-05-15 | Loders Croklaan Bv | CONCENTRATE OF TRITERPENES |
CA2446748C (en) | 2001-05-11 | 2011-03-08 | University Of Ottawa | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods |
US20040082521A1 (en) | 2002-03-29 | 2004-04-29 | Azaya Therapeutics Inc. | Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases |
CA2487732C (en) * | 2002-05-28 | 2013-10-15 | Bette Pollard | Cardiac glycosides to treat cystic fibrosis and other il-8 dependent disorders |
US7179484B2 (en) | 2002-11-06 | 2007-02-20 | Azaya Therapeutics, Inc. | Protein-stabilized liposomal formulations of pharmaceutical agents |
WO2004087121A2 (en) | 2003-03-28 | 2004-10-14 | Azaya Therapeutics, Inc. | Water soluble formulations of digitalis glycosides for treating cell-proliferative and other diseases |
RU2387665C2 (en) | 2004-03-17 | 2010-04-27 | Панакос Фармасьютикалз, Инк. | Pharmaceutical salts of 3-o-(3',3-dimethylsuccinyl) betulinic acid |
US7118508B2 (en) | 2004-07-28 | 2006-10-10 | General Motors Corporation | Planetary transmissions having three interconnected gear members and clutched input members |
EP1858910B1 (en) | 2005-02-09 | 2010-11-03 | Dabur Pharma Ltd. | Novel betulinic acid derivatives a-ring-condensed to a heterocyclic group |
AU2006230429A1 (en) | 2005-03-29 | 2006-10-05 | Regents Of The University Of Minnesota | Selective oxidation of triterpenes employing TEMPO |
US20060252733A1 (en) | 2005-04-07 | 2006-11-09 | Novelix Pharmaceuticals, Inc. | Betulin, betulin derivatives, betulinic acid and betulinic acid derivatives as novel therapeutics in the treatment of disease of lipid and/or glucose metabolism |
WO2006133314A2 (en) | 2005-06-08 | 2006-12-14 | Regents Of The University Of Minnesota | Synthesis of betulonic and betulinic aldehydes |
WO2006132033A1 (en) | 2005-06-10 | 2006-12-14 | Pola Chemical Industries Inc. | Novel triterpenic acid derivative and preparation for external application for skin comprising the same |
US7402325B2 (en) * | 2005-07-28 | 2008-07-22 | Phoenix Biotechnology, Inc. | Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander |
AU2006333084A1 (en) | 2005-12-16 | 2007-07-12 | Panacos Pharmaceuticals, Inc. | Preparation of pharmaceutical salts of 3-O-(3',3'-dimethylsuccinyl) betulinic acid |
EP1803461A1 (en) * | 2005-12-27 | 2007-07-04 | Heinz-Herbert Fiebig | Therapeutic use of an extract from the leaves of Nerium oleander |
GB0604535D0 (en) | 2006-03-07 | 2006-04-12 | Sndv Sprl | Betulonic acid derivatives |
US20090203661A1 (en) | 2006-10-12 | 2009-08-13 | Safe Stephen H | Betulinic acid, derivatives and analogs thereof and uses therefor |
WO2008057420A2 (en) | 2006-11-03 | 2008-05-15 | Panacos Pharmaceuticals, Inc. | Extended triterpene derivatives |
WO2008091532A1 (en) | 2007-01-19 | 2008-07-31 | Panacos Pharmaceuticals, Inc. | Salts of 3-o-(3',3'-dimethylsuccinyl)betulinic acid and solid state forms thereof |
US8987212B2 (en) | 2007-08-07 | 2015-03-24 | Muhammed Majeed | Oleanoyl peptide composition and method of treating skin aging |
AU2008321225B2 (en) | 2007-11-13 | 2013-08-01 | Phoenix Biotechnology Inc. | Method of determining the probability of a therapeutic response in cancer chemotherapy with cardiac glycoside |
CN102083442B (en) | 2008-04-18 | 2014-08-13 | 里亚塔医药公司 | Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at C-17 |
KR101713140B1 (en) | 2008-04-18 | 2017-03-08 | 리타 파마슈티컬스 잉크. | Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring |
TWI584808B (en) | 2008-04-18 | 2017-06-01 | 瑞塔醫藥有限責任公司 | Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives |
WO2009146216A2 (en) | 2008-04-18 | 2009-12-03 | Reata Pharmaceuticals. Inc. | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
WO2010028487A1 (en) | 2008-09-10 | 2010-03-18 | Université Du Québec À Chicoutimi | Bidesmosidic betulin and betulinic acid derivatives and uses thereof as antitumor agents |
US8778990B2 (en) | 2008-11-04 | 2014-07-15 | Trustees Of Dartmouth College | Betulinic acid derivatives and methods of use thereof |
US8802727B2 (en) | 2009-07-14 | 2014-08-12 | Hetero Research Foundation, Hetero Drugs Limited | Pharmaceutically acceptable salts of betulinic acid derivatives |
CN101704872B (en) | 2009-11-23 | 2012-06-27 | 张南 | 23-hydroxybetulinic acid derivatives as well as preparation methods and application thereof |
WO2011064710A1 (en) | 2009-11-30 | 2011-06-03 | University Of Kwazulu-Natal | In vitro anti-sickling activity of betulinic acid, oleanolic acid and their derivatives |
AU2011203933B2 (en) | 2010-01-11 | 2016-01-21 | Phoenix Biotechnology, Inc. | Method of treating neurological conditions with cardiac glycosides |
US9011937B2 (en) | 2010-11-22 | 2015-04-21 | Phoenix Biotechnology, Inc. | Method of treating neurological conditions with extract of Nerium species or Thevetia species |
TWI386415B (en) | 2010-02-02 | 2013-02-21 | Univ Kaohsiung Medical | Ursolic acid derivative and pharmaceutical composition thereof |
TWI410431B (en) | 2010-12-22 | 2013-10-01 | Ind Tech Res Inst | Use of oleanolic acid derivatives in the manufacture of a medicament to prevent or treat hepatitis c |
US20140221328A1 (en) | 2011-01-10 | 2014-08-07 | Bandi Parthasaradhi Reddy | Pharmaceutically acceptable salts of novel betulinic acid derivatives |
HUE026371T2 (en) | 2011-01-31 | 2016-05-30 | Bristol Myers Squibb Co | C-28 amines of c-3 modified betulinic acid derivatives as hiv maturation inhibitors |
CN102558280B (en) | 2011-11-18 | 2014-09-17 | 温州大学 | Method for producing 30-halogenated betulinic acid |
JP6211527B2 (en) | 2011-12-01 | 2017-10-11 | ハンジョウ ベンシェン ファーマシューティカル シーオー., エルティーディー.Hangzhou Bensheng Pharmaceutical Co., Ltd. | 2-substituted oleanolic acid derivatives, their preparation and use |
DK2787002T3 (en) | 2011-12-01 | 2016-08-29 | Hangzhou Bensheng Pharmaceutical Co Ltd | Oleanolsyreamidat derivatives, methods of making and uses thereof |
US20150119373A1 (en) | 2012-04-24 | 2015-04-30 | Hetero Research Foundation | Novel betulinic acid derivatives as hiv inhibitors |
US8921419B2 (en) | 2012-05-08 | 2014-12-30 | Trustees Of Dartmouth College | Triterpenoids and compositions containing the same |
WO2014027777A2 (en) | 2012-08-14 | 2014-02-20 | 한국콜마 주식회사 | Novel ursolic acid derivative and method for preparing same |
US9278912B2 (en) | 2012-09-10 | 2016-03-08 | Reata Pharmaceuticals, Inc. | C13-hydroxy derivatives of oleanolic acid and methods of use thereof |
ES2644615T3 (en) | 2012-09-10 | 2017-11-29 | Reata Pharmaceuticals, Inc. | C17 heteroaryl derivatives of oleanolic acid and their methods of use |
US9593074B2 (en) | 2012-09-10 | 2017-03-14 | Reata Pharmaceuticals, Inc. | C17-alkanediyl and alkenediyl derivatives of oleanolic acid and methods of use thereof |
US9637516B2 (en) | 2012-12-31 | 2017-05-02 | Hetero Research Foundation | Betulinic acid proline derivatives as HIV inhibitors |
MX2015010354A (en) | 2013-02-25 | 2015-10-09 | Squibb Bristol Myers Co | C-3 alkyl and alkenyl modified betulinic acid derivatives useful in the treatment of hiv. |
EP3105241A1 (en) * | 2014-02-12 | 2016-12-21 | Organo Balance GmbH | Yeast strain and microbial method for production of pentacyclic triterpenes and/or triterpenoids |
WO2015195776A1 (en) | 2014-06-19 | 2015-12-23 | Bristol-Myers Squibb Company | Betulinic acid derivatives with hiv maturation inhibitory activity |
US9492438B2 (en) * | 2014-07-25 | 2016-11-15 | Bette Pollard | Amphiphilic pyridinum compounds to treat epilepsy and other disorders of the nervous system |
CN108348469A (en) * | 2015-06-08 | 2018-07-31 | 德马克有限责任公司 | Therapeutic composition |
-
2018
- 2018-07-16 JP JP2020515911A patent/JP6820450B2/en not_active Expired - Fee Related
- 2018-07-16 CA CA3075729A patent/CA3075729A1/en active Pending
- 2018-07-16 EP EP18857189.7A patent/EP3681508A4/en not_active Withdrawn
- 2018-07-16 KR KR1020217026676A patent/KR20210107904A/en active IP Right Grant
- 2018-07-16 WO PCT/US2018/042226 patent/WO2019055119A1/en unknown
- 2018-07-16 KR KR1020207007406A patent/KR102295179B1/en active IP Right Grant
- 2018-07-16 AU AU2018334386A patent/AU2018334386B2/en active Active
- 2018-07-16 MX MX2020002883A patent/MX2020002883A/en unknown
- 2018-07-16 RU RU2020113341A patent/RU2020113341A/en unknown
- 2018-07-16 IL IL285232A patent/IL285232B/en unknown
-
2020
- 2020-03-09 IL IL273162A patent/IL273162B/en unknown
- 2020-06-25 AU AU2020204236A patent/AU2020204236B2/en active Active
-
2021
- 2021-01-04 JP JP2021000190A patent/JP7037673B2/en active Active
-
2022
- 2022-03-04 JP JP2022033642A patent/JP2022075755A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2020204236A1 (en) | 2020-07-16 |
JP7037673B2 (en) | 2022-03-16 |
KR20200081356A (en) | 2020-07-07 |
CA3075729A1 (en) | 2019-03-21 |
IL273162A (en) | 2020-04-30 |
KR20210107904A (en) | 2021-09-01 |
RU2020113341A (en) | 2021-10-15 |
JP6820450B2 (en) | 2021-01-27 |
AU2020204236B2 (en) | 2020-12-10 |
IL285232B (en) | 2022-07-01 |
EP3681508A1 (en) | 2020-07-22 |
EP3681508A4 (en) | 2021-05-19 |
JP2022075755A (en) | 2022-05-18 |
IL273162B (en) | 2021-08-31 |
AU2018334386A1 (en) | 2020-04-02 |
KR102295179B1 (en) | 2021-08-30 |
AU2018334386B2 (en) | 2021-11-04 |
JP2020534293A (en) | 2020-11-26 |
JP2021063105A (en) | 2021-04-22 |
IL285232A (en) | 2021-09-30 |
WO2019055119A1 (en) | 2019-03-21 |
MX2020002883A (en) | 2020-10-05 |