RU2018107491A - Antisense oligonucleotide of the 5´-untranslated region of the APOE gene - Google Patents

Antisense oligonucleotide of the 5´-untranslated region of the APOE gene Download PDF

Info

Publication number
RU2018107491A
RU2018107491A RU2018107491A RU2018107491A RU2018107491A RU 2018107491 A RU2018107491 A RU 2018107491A RU 2018107491 A RU2018107491 A RU 2018107491A RU 2018107491 A RU2018107491 A RU 2018107491A RU 2018107491 A RU2018107491 A RU 2018107491A
Authority
RU
Russia
Prior art keywords
apoe gene
untranslated region
antisense oligonucleotide
expression
apoe
Prior art date
Application number
RU2018107491A
Other languages
Russian (ru)
Other versions
RU2018107491A3 (en
Inventor
Татьяна Николаевна Паметова
Original Assignee
Татьяна Николаевна Паметова
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Татьяна Николаевна Паметова filed Critical Татьяна Николаевна Паметова
Priority to RU2018107491A priority Critical patent/RU2018107491A/en
Publication of RU2018107491A3 publication Critical patent/RU2018107491A3/ru
Publication of RU2018107491A publication Critical patent/RU2018107491A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (4)

1. Антисмысловой олигонуклеотид, повышающий экспрессию гена АРОЕ, состоящий из 5-50 нуклеотидов, направленный на 5'-нетранслируемую область гена АРОЕ.1. Antisense oligonucleotide that increases the expression of the APOE gene, consisting of 5-50 nucleotides, aimed at the 5'-untranslated region of the APOE gene. 2. Способ повышения экспрессии гена АРОЕ, включающий доставку олигонуклеотида по п. 1, к 5'-нетранслируемой области гена АРОЕ.2. A method of increasing the expression of the APOE gene, including the delivery of the oligonucleotide according to claim 1, to the 5'-untranslated region of the APOE gene. 3. миРНК, подавляющая экспрессию гена АРОЕ, состоящая из 5-50 нуклеотидов, гибридизующаяся с 5'-нетранслируемой областью гена АРОЕ.3. siRNA, which suppresses the expression of the APOE gene, consisting of 5-50 nucleotides, hybridizing with the 5'-untranslated region of the APOE gene. 4. Способ подавления экспрессии гена АРОЕ, включающий доставку миРНК, гибридизующейся с 5'-нетранслируемой областью гена АРОЕ, состоящей из 5-50 нуклеотидов, к 5'-нетранслируемой областью гена АРОЕ.4. A method of suppressing the expression of the APOE gene, including the delivery of siRNA hybridizing with the 5'-untranslated region of the APOE gene, consisting of 5-50 nucleotides, to the 5'-untranslated region of the APOE gene.
RU2018107491A 2018-03-01 2018-03-01 Antisense oligonucleotide of the 5´-untranslated region of the APOE gene RU2018107491A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2018107491A RU2018107491A (en) 2018-03-01 2018-03-01 Antisense oligonucleotide of the 5´-untranslated region of the APOE gene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2018107491A RU2018107491A (en) 2018-03-01 2018-03-01 Antisense oligonucleotide of the 5´-untranslated region of the APOE gene

Publications (2)

Publication Number Publication Date
RU2018107491A3 RU2018107491A3 (en) 2019-09-03
RU2018107491A true RU2018107491A (en) 2019-09-03

Family

ID=67903248

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107491A RU2018107491A (en) 2018-03-01 2018-03-01 Antisense oligonucleotide of the 5´-untranslated region of the APOE gene

Country Status (1)

Country Link
RU (1) RU2018107491A (en)

Also Published As

Publication number Publication date
RU2018107491A3 (en) 2019-09-03

Similar Documents

Publication Publication Date Title
MX2020011570A (en) Extrahepatic delivery.
JP2017079776A5 (en)
JP2016526529A5 (en)
JP2012070736A5 (en)
EA201791820A1 (en) OLIGONUCLEOTIC THERAPY OF CONGENITAL AMAUROSIS LEBER
JP2015142558A5 (en)
MX2018004160A (en) 3' utr sequences for stabilization of rna.
JP2017002079A5 (en)
JP2012136542A5 (en)
JP2018513668A5 (en)
IL288490A (en) Antisense rna editing oligonucleotides comprising cytidine analogs
JP2013226147A5 (en)
JP2016528887A5 (en)
EP2788087A4 (en) Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
WO2009017803A3 (en) Antisense microrna and uses therefor
EA201791986A1 (en) Oligonucleotides, corresponding to exon 73 of the COL7A1 gene, for the therapy of bulletic epidermolysis
EP2896696A3 (en) Modifications for antisense compounds
SG11202008687XA (en) Increasing tissue specific gene delivery by capsid modification
WO2016134146A3 (en) Rna interference therapeutics against ebola virus
IL304679A (en) Antisense oligonucleotides increasing foxg1 expression
RU2018107491A (en) Antisense oligonucleotide of the 5´-untranslated region of the APOE gene
AR083445A1 (en) siRNA AGAINST FIBROSIS
RU2018107485A (en) Antisense oligonucleotide of the 5'-untranslated region of the CRE gene
RU2018107486A (en) Antisense oligonucleotide of the 5´-untranslated region of the CREBBP gene
RU2018107483A (en) Oligonucleotide hybridizing with the 5'-untranslated region of the CYP17 gene