RU2015115948A - 4 - [(4-Acetoxybenzoyl) amino] lithium butyrate with cerebroprotective effect - Google Patents

4 - [(4-Acetoxybenzoyl) amino] lithium butyrate with cerebroprotective effect Download PDF

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Publication number
RU2015115948A
RU2015115948A RU2015115948A RU2015115948A RU2015115948A RU 2015115948 A RU2015115948 A RU 2015115948A RU 2015115948 A RU2015115948 A RU 2015115948A RU 2015115948 A RU2015115948 A RU 2015115948A RU 2015115948 A RU2015115948 A RU 2015115948A
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Prior art keywords
acetoxybenzoyl
amino
lithium butyrate
cerebroprotective effect
butyrate
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RU2015115948A
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Russian (ru)
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RU2617233C2 (en
Inventor
Анатолий Кузьмич Брель
Иван Николаевич Тюренков
Светлана Викторовна Лисина
Юлия Николаевна Будаева
Елена Владимировна Волотова
Денис Владимирович Куркин
Дмитрий Александрович Бакулин
Original Assignee
Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации ГБОУ ВПО ВолгГМУ МЗ РФ
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Priority to RU2015115948A priority Critical patent/RU2617233C2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Применение нового водорастворимого производного гамма-аминомасляной кислоты - 4-[(4-Ацетоксибензоил)амино]бутират лития - формулыв качестве средства для лечения ишемических нарушений мозгового кровообращения.The use of a new water-soluble derivative of gamma-aminobutyric acid - 4 - [(4-Acetoxybenzoyl) amino] lithium butyrate - formulas as a tool for the treatment of ischemic disorders of cerebral circulation.

Claims (1)

Применение нового водорастворимого производного гамма-аминомасляной кислоты - 4-[(4-Ацетоксибензоил)амино]бутират лития - формулыThe use of a new water-soluble derivative of gamma-aminobutyric acid - 4 - [(4-Acetoxybenzoyl) amino] lithium butyrate - formula
Figure 00000001
Figure 00000001
 в качестве средства для лечения ишемических нарушений мозгового кровообращения. as a tool for the treatment of ischemic cerebrovascular accident.
RU2015115948A 2015-04-27 2015-04-27 4-[(4-acetoxybenzoyl)amino]butyrate of lithium, having cerebroprotective action RU2617233C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2015115948A RU2617233C2 (en) 2015-04-27 2015-04-27 4-[(4-acetoxybenzoyl)amino]butyrate of lithium, having cerebroprotective action

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2015115948A RU2617233C2 (en) 2015-04-27 2015-04-27 4-[(4-acetoxybenzoyl)amino]butyrate of lithium, having cerebroprotective action

Publications (2)

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RU2015115948A true RU2015115948A (en) 2016-11-20
RU2617233C2 RU2617233C2 (en) 2017-04-24

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2748035C1 (en) * 2020-10-08 2021-05-19 Общество С Ограниченной Ответственностью "Научно-Производственное Объединение "Фарматрон" Combined drug for pharmacorrection of cognitive dysfunctions after ketamine anesthesia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
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RU2216322C1 (en) * 2002-02-28 2003-11-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Agent eliciting anti-ischemic, hypotensive, anti- -arrhythmic and nootropic activity
CN101544579B (en) * 2009-05-07 2013-05-22 兰州大学 Use and preparation method of 4-(-2-acetoxybenzoyl)aminobutyric acid and ester derivative thereof
RU2495866C1 (en) * 2012-06-19 2013-10-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации Gamma-aminobutyric acid derivative, having nootropic activity coupled with tranquilising activity

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